CA2164229C - Skin treatment method utilizing an alpha-hydroxy acid composition and an applicator pad - Google Patents

Skin treatment method utilizing an alpha-hydroxy acid composition and an applicator pad Download PDF

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CA2164229C
CA2164229C CA002164229A CA2164229A CA2164229C CA 2164229 C CA2164229 C CA 2164229C CA 002164229 A CA002164229 A CA 002164229A CA 2164229 A CA2164229 A CA 2164229A CA 2164229 C CA2164229 C CA 2164229C
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skin
composition
peeling
exfoliating
grams
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CA2164229A1 (en
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Burt Shaffer
Jeffrey Rapaport
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RAPAPORT MARC
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RAPAPORT MARC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q9/00Preparations for removing hair or for aiding hair removal
    • A61Q9/04Depilatories
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method employing a novel combination of a skin care composition and cosmetic applicator pad is provided for at-home skin degreasing, peeling and/or exfoliating and moisturizing, which is gentle in that the concentrations of the active skin peeling and/or degreasing, exfoliating and moisturizing ingredient, principally an alpha hydroxy acid, or a mixture of alpha hydroxy acids, preferably including acetone, is far lower than that routinely used for professional use in the offices of professional dermatologists, aestheticians and/or cosmetologists. The composition of the present invention is provided in a suitable pharmaceutical vehicle and is presaturated into a convenient cosmetic applicator pad.

Description

SKIN TREATMENT METHOD UTILIZING AN ALPHA-HYDROXY ACID
COMPOSITION AND AN APPLICATOR PAD
The present invention relates to topical compositions for producing healthy, youthful, attractive, natural, looking human skin, and for addressing certain problem skin conditions, including aging skin, dry skin, photo aged skin, i.e., sun damaged skin, hyperpigmentation [brown and black blotchesJ or darkly pigmented skin [e.g. natural skin pigmentation of black persons], acne, eczema, thin skin, which occurs commonly in Caucasian women between the ages of 25 and 40, where skin thickness is reduced, sensitive skin and composite dry-oily skin also known as T-zone oily skin.
BACKGROUND OF THE INVENTION
It is known ttiat the epidermal, or outer layers of human skin can be caused to peel by applying alpha hydroxy acid ("AHA") containing preparations, such as glycolic acid, in order to remove dead skin and to wound underlying living skin tissue. The beneficial result of such skin peeling is that when underlying layers of skin are exposed, the underlying skin is relatively free of age lines, superficial wrinkles, acne scarring, scaliness, pigment spots, aging spots, acne lesions, and, with an appropriate topical composition, without the same relative degree of hyperpigmentation as compared to the same skin before a topical peeling composition was applied.
Removing old, dead surface skin cells exposes younger underlying skin tissue, which looks more youthful in part because it is smoother and reflects light more readily, thus rendering a"healthy glow" appearance. Removal of the buildup of dead skin cells is critical to producing younger-looking skin because the dead cell buildup is partly responsible for the rough, dry look associated with superficial fine lines, crow's feet, wrinkles and the like.
Skin exfoliation involves removing the surface layer of dead skin cells. To accomplish this, the surface dead cells must be penetrated and either removed by manual met}iods employing mechanical activity or by chemical methods in which surface dead cells must be penetrated by the exfoliating agents.
The present invention also uses AHAs, and preferably and particularly the AHA glycolic acid, as an agent to loosen the bonds between dead skin cells and underlying living tissue and stimulate the living skin tissue to form new collagen and to metabolically remove and reorganize dead cells and detritus.
In contrast, products which are solely peeling agents and/or exfoliants, such as salicylic acid, even when provided in an applicator pad, involve only contact with and removal of all or a portion of the surface dead skin, without affecting the underlying living skin tissue.
Exfoliation of the skin is a more gentle skin treatment process than chemical peeling, since exfoliation, unlike peeling, removes only dead skin cells from the skin surface and does not wound living cells. Peeling, in contrast, wounds living skin cells and stimulates both healing and the production of collagen and other cellular materials.
DISCUSSION OF THE PRIOR ART
Various attempts have been made to utilize alpha-hydroxy acids, such as glycolic acid, in skin care products, as noted in U.S. patent Numbers 3,879,537, 3,920,835, 3,984,566, 3,988,470, 4,021,572, 4,105,783, 4,197,316, 4,234,599, 4,246,261, 4,363,815, 4,380,549, and 4,363,815 of Van Scott and Yu, as well as U.S. Patent Numbers 4,294,852 of Wildnauer.
However, such patents do not disclose the use of an alpha-hydroxy acid, such as glycolic acid, impregnated into a pad, such as a medicated cleansing pad or a cosmetic applicator pad for frequent periodic use and the application thereof.
Cosmetic applicator pads and/or medicated cleansing pads fabricated for very specific material compositions have been described in use with salicylic acid and alcohol, as noted in U.S. patent no. 4,891,228 of Thaman.

However, alpha hydroxy acids, such as glycolic acid are much better at treating skin conditions, because of their activity in relation to the removal of dead skin layers and moisturizing and treating live skin. Moreover, glycolic acid is the preferred alpha hydroxy acid because it penetrates the dermal layers better by virtue of its relatively smaller molecular size than other alpha hydroxy acids having larger molecular sizes, such as lactic acid.
Alternatively, glycolic acid acts at peeling and/or exfoliating skin when used synergistically in combination with relatively low concentrations of acetone.
Other related preparations for skin treatment include U.S. patent Nos. 4,035,513 of Kumano, 4,124,720 of Wenmaekers, 4,195,077 of Marsh, 4,287,214 of Van Scott and Yu, 4,608,370 of Aronsohn, 4,695,452 of Gannis, 4,824,865 of Bowser, 4,830,854 of Copelan, 4,931,591 of Buhlmayer, 5,110,603 of Rau and 5,164,413 of Willis.
In connection with the alternate topical use of acetone, the following prior art is relevant: U.S patent 5,133,967 to Smith for a skin toning composition which proposes the use of glycol ether instead of acetone and alcohol to degrease and de-fat the skin. U.S. patent 5,154,174 describes the use of acetone as a skin drying agent in preparation for attachment of transdermal electrodes to the skin. U.S. patents 5,145,858 and 5,140,047, 5,134,150 and 4,847,270 for bactericides teach acetone for drying the skin, in conjunction with moisturizers, such as glycerol or castor oil. U.S.
5,091,379 describes acetone in an anti-inflammatory composition. U.S. patent 5,049,381 and 4,980,378 disclose the use of acetone for penetration of skin tanning coloration compositions or products. Moreover, the New Jersey Department of Health "Hazardous Substances Fact Sheet: Acetone" Cas. No. 67-64-1, DOT No. UN 1090 Feb.
1989 warns that excessive use of acetone causes skin dryness.
However, none of these prior art documents teach the use of acetone as a peeling agent, as opposed to a drying 21.64229 agent. However, such use can be supported, since in high concentrations acetone has been shown to cause blistering or excessive peeling by abnormal erosion of skin layers, as noted in Kechijian, "Nail Polish Removers: Are They Harmful?", Dept. of Dermatology, N.Y.U. School of Medicine, New York, N.Y., published by W.B. Saunders Company, 1991.
In the prior art, chemical peeling has been done in dermatologists' aestheticians' and cosmetologists' offices, and has been accomplished over a period of minutes or hours, generally in a single visit. The problems with such chemical peels include use of relatively high concentrations of such peeling agents as AHAs, including the use of glycolic acid, trichloroacetic acid and phenol compounded into a suitable vehicle, with concentrations being typically from 30% up to as much as 90% in the prior art. Traditional chemical peeling, then, has been swift, harsh, often painful, and, due to the harshness has been undesirable.
In the course of chemical peeling surface debris, including dead skin cells, are removed partly through mechanical abrasive action of applying and removing the chemical peel agents and partly through the activity of the chemical peeling agents which, among other effects, break bonds by which dead skin cells adhere to living skin cells.
In the prior art, peeling agents have been applied and then neutralized and/or physically removed from the skin after the desired treatment time period has elapsed.
Chemical peeling can be done in varying degrees of depth, typically called light, or superficial, and medium and deep peels. A light peel is generally one which is comparatively superficial in effect and a deep chemical peel is one in which peeling agents are used to produce a moderate to severe wound to the skin. However, a deep peel achieves a much more profound effect, and does so quickly, in minutes or hours. As a result, pain and inflammation usually result. Deep peeling usually produces redness lasting several days, a large and deep separation of dead skin, and the exposure of what, before the deep peel, was relatively deep living skin tissue.
The results of deep peeling are not equivalent to the results of light or superficial peels or exfoliation.
5 Whereas deep peeling potentially produces undesirable redness, itching, pain, inflammation and unwanted or excessive peeling of living tissue which may last days after the deep peel treatment, light peels produce few or no such undesirable side effects. The cosmetic results of deep peeling are more dramatic and more visible than the results available with light and medium peeling and exfoliation.
But where excessive or prolonged and unwanted peeling occurs in the aftermath of a deep peel treatment, it is difficult or impossible to apply cosmetics to the affected skin due to the continued peeling and due to the pain, itching, inflammation and redness of the skin.
However, it should be noted that prior art peeling is accomplished by the application of high-concentration peeling agents either in a single treatment session, or, at most, over a period of repetitive treatments over several days or weeks in a professional setting, i.e., the office of a dermatologist, an aesthetician or a cosmetologist.
As a general matter, skin to be peeled has been first degreased in the prior art. In some prior art, there has also been another intermediate preparatory step in which various agents are applied to the skin in order to more effectively degrease it. After the skin is prepared by degreasing, the peeling agents have been applied in the prior art. The peeling agents are then neutralized and/or removed after a non-standardized duration. Finally, affected skin has been topically treated with a moisturizer or other after-care preparation.
Moreover, even where mere exfoliants are used, such as salicylic acid in combination with alcohol, as disclosed in Thaman, the results are not as beneficial as in the present invention, where alpha hydroxy acids are used.
The AHA's of the present invention serve not only as agents for skin peeling and/or exfoliating, but also as skin moisturizers, by virtue of their humectant qualities.
In addition, the prior art does not provide for standardization of peeling or exfoliation. For example, a professional practitioner, i.e., a dermatologist, aesthetician or cosmetologist applies skin peeling agents which the practitioner has purchased containing individual ingredients such as glycolic acid. Prior art practitioners have used a variety of application methods, with no standardized quantity of agents being applied. Therefore there is no standardization of any part of the chemical peeling process in any of the prior art. By so doing, there can be no standardization of peeling materials or their concentrations among skin treatment practitioners.
In addition to the widely variable ingredients and concentrations of skin peel agents, there has been no standardization in the preparation of skin before application of the peeling agents, no standardization of the duration of skin contact with the peeling agents, no standardization of the degree of abrasiveness employed in the course of treatment, and no standardization of post-treatment for affected skin. The aforementioned lack of standardization has produced unpredictable results in the art of skin peeling/exfoliation.
As a general matter,.skin to be peeled has been first cleansed in the prior art. In some prior art, there has also been another intermediate preparatory step in which various agents are applied to the skin in order to more effectively degrease it. After the skin is prepared by cleansing and/or degreasing, the peeling agents have been applied in the prior art. The peeling agents are then neutralized and/or removed after a non-standardized duration. Finally, affected skin has been topically treated with a moisturizer or other after-care preparation.
Additional disadvantages of the prior art have been the nonstandardization in the additional critical areas of variability in the effectiveness and depth of skin penetration achieved by the skin peeling agents, due to uncontrolled variability in preparatory degreasing;
variability in types and concentrations of peeling agents due to the presence or absence of solvents such as alcohol mixed with and applied w.ith the peeling agents themselves;
variability in the duration of peeling agent contact with the skin; variability in degree of abrasiveness employed in the course of skin peeling or exfoliation; and, variability in the materials, manner and frequency of post-peel skin treatment. There is also no way for a professional to know how much of the peeling agent to apply as the dose has not been premeasured or standardized.
FEATURES OF THE INVENTION
It is a feature of one embodiment of the present invention to provide a skin peeling/exfoliating system for at-home use.
It is another feature of preferred embodiments of the present invention to provide a skin peeling/exfoliating system which eliminates the necessity for expensive inconvenient professional supervision for peeling or exfoliation skin treatment. It is a further feature of the present invention to provide, in preferred embodiments, a skin peeling/exfoliating system involving frequented repeated application of peeling/exfoliating agents over a selected period of days to obtain predictable, reliable results.
It is another feature of a preferred embodiment of the present invention to provide a skin peeling/exfoliating treatment system treatment employing a skin peeling/
exfoliating agent which comprises a unique combination of skin peeling/exfoliating materials.
It is another feature of the present invention, in preferred embodiments, to provide a skin peeling/exfoliating treatment system employing a delivery system using cosmetic applicator pads and/or medicated applicator pads, preferably having a selected degree of abrasiveness.
It is another feature of preferred forms of the present invention to provide a skin peeling/exfoliating treatment system employing a delivery system using cosmetic applicator pads and/or medicated applicator pads presaturated with a desired quantity of a skin peeling exfoliating agent.
It is another feature of the present invention to provide, in preferred embodiments, a skin peeling/
exfoliating treatment system employing a'plurality of applicator pads saturated with materials for frequent periodic peeling/exfoliating steps which are also moisturizing steps.
It is another feature of a preferred embodiment of the present invention to provide a skin peeling/exfoliating treatment system which provides a method of treating and improving the appearance of skin subject to a variety of conditions, including aging skin, hyperpigmentation, acne, sensitive skin, dry-oily skin and the like.
It is another feature of a preferred embodiment of the present invention to provide a skin peeling/exfoliating treatment system wherein the skin peeling/exfoliating agent is left on the skin, and which, by the virtue of leaving it on, becomes a skin moisturizer.
It is yet another feature of a preferred embodiment of the present invention to provide a skin degreasing, skin peeling and/or exfoliating treatment system with a cosmetic and/or medicated applicator pad which provides an agent which is left on the skin, and which, by the virtue of leaving it on, serves as both a skin moisturizer and a treatment for the skin.
SUMMARY OF THE INVENTION
In addressing the problems found in the prior art, the present invention provides a method of treatment for skin 8a conditions, including an abrasive and absorbent applicator pad, preferably in a kit or at home use, for delivery of a composition for effective skin peeling and exfoliation as well as moisturization which is applied in concentrations of the active skin peeling ingredients far lower than that routinely used in dermatologists' offices. In addition, if used at frequent periodic intervals, such as daily, over a period of a few weeks, the use of the composition, preferably applied with an applicator pad, provides a light at-home chemical skin peel. The composition of the present invention, preferably as delivered by the pad, provides an effective composition and method in that the controlled concentration of at least one peeling agent permits the 2tG4229 peeling agent to be left on the skin of the user for a relatively extensive duration.
It is to be noted that the peeling agents of the various embodiments of the present invention may be treatment compositions containing a single alpha hydroxy acid (AHA) or a combination of the AHAs as set forth in detail hereinafter.
Frequent periodic treatment of the skin and long-duration skin contact with the peeling agents effects the slow peeling results which are an object of the present invention. In addition, the efficacy of the present invention substantially avoids irritating or wounding the skin in a manner perceptible to the user is a further novel advantage.
Because the peeling/exfoliation treatment composition of the present invention is thus effective without skin irritation or wounding which is perceptible, the composition of the present invention may be, and is intended to be left upon the skin of the user without the neutralization or removal required in the prior art. Thus, the present invention is designed to be used at least once daily over a period of weeks to produce the same or a superior result compared to light or superficial chemical peels alone.
The alternate embodiment of the present invention is better than a cream containing AHAs and/or glycolic acid because the acetone in the alternate embodiment of the present invention acts as a further peeling agent in its own right and further acts as an aggressive solvent to strip the skin of oil and grease and thus allows the exfoliating agents to penetrate deeper. An exfoliating agent in a cream base treatment composition which fails to employ acetone cannot penetrate as deeply and thus cannot achieve the superior results of the present invention.
Thus, with the alternate acetone component of the present invention, the exfoliating agents penetrate deeper and are more effective in exfoliating the skin. The key novel aspects is the present invention's ability to deliver the degreasing, exfoliating and moisturizing agents to the appropriate layers of skin where degreasing, exfoliating and moisturizing is to occur. , In contrast to the prior art which requires expensive and potentially inconvenient professional treatment for skin exfoliation, the present invention provides convenient and inexpensive skin degreasing, exfoliating and moisturizing at home, in a non-professional setting, utilizing treatment compositions containing exfoliating 10 and/or degreasing or moisturizing agents applied only once per day over a period lasting a minimum of five days. Other differences between the present invention and the prior art will be fully set forth herein.
In addressing the aforementioned features, the present invention provides a composition, a method of treatment and a treatment applicator pad for at-home skin exfoliating and/or degreasing or moisturizing, which is gentle in that the concentrations of the active skin exfoliating and/or degreasing or moisturizing ingredients are far lower than ttiat utilized in the professional offices of dermatologists, cosmetologists and aestheticians.
The composition of the present invention is designed to be used at least once daily over a period of weeks to produce the same or a superior result compared to chemical peels available in an intense, harsh dermatological treatment lasting merely for a period of minutes or hours.
The present invention is better than prior art AHA
containing creams or lotions because the use of the applicator pad debrides the skin, thereby providing better penetration of the skin layers by the AHAs. Better penetration, in turn, permits the slow peeling and/or exfoliating which is the object of using the AHAs. The use of at least one AIIA with the applicator pad of the present invention provides a convenient, user-friendly product intended for at least once daily use in a non-professional setting, such as at the home of the user.
The pads themselves are effective in removing the dead skin debris, dirt and oil in that the pad removes these materials. In addition, the applicator pad, which is presaturated with the AHA material, leaves the low-concentration AHA material on the skin while removing unwanted debris, dirt and oil. The clearing of debris, dirt and oil and simultaneous AfiA topical application allows far greater AHA efficacy than if the AtiAs were applied to dirty, unprepared skin. In addition, the pad enables greater AHA efficacy than if the skin had been simply cleansed prior to ttie application of the AIiAs.
Ttie pads themselves are commercially available flexible, absorbant, sponge-like cosmetic applicator pads whicti allow the presaturated AHAs to be expressed onto the skin with mild manual pressure and which also provide abrasion when drawn across the skin with mild to moderate manual pressure.
Mildly abrasive cosmetic applicat-or pads are commercially available under the name *SONTARA pads, described as a non-woven/spun laced pad comprised of rayon and polyester from KLEEN TEST PRODUCTS, P.O. Box 574 Milwaukee, WI. Moderately abrasive cosmetic applicator pads, also available from KLEEN TEST PRODUCTS are described as *NOVO pads.
Mildly abrasive and absorbant pads, e.g., SONTARA
pads, are used for AHA preparations which have a relatively low-viscosity liquid or liquid-like pharmaceutical vehicle.
The moderately abrasive NOVO pads can be used with the same relatively low-viscosity liquid or liquid-like pharmaceutical vehicle, but the NOVO pads can also be used with AFIA preparations with higher viscosities, such as lotions, creams and lipid-based pharmaceutical vehicles.
Strongly abrasive pads, such as the BUFF PUFF pad can also be presaturated with AlIAs in a pharmaceutical vehicle, but strongly abrasive applicators are not preferred in the present invention.
'I'he above-mentioned cosmetic applicator pads may also be manufactured in a two-sided embodiment. One side has relatively greater abrasiveness and the remaining side is less abrasive. The more abrasive side of the pad is used *Trade-mark to debride the skin, loosening and removing dead skin cells and debris, while at the same time depositing a material with which the pad has been presaturated. Such material is typically, but not necessarily, the peeling and/or exfoliating agent of the present invention. The pad, presaturated with an alternate material, could be used to apply a cleanser or a skin degreasing composition.
The two-sided pad's less abrasive side is used to absorb dirt, skin oil and debris from the skin to be treated. The user first applies the more abrasive side of the two-sided pad by gently wiping the skin to be treated with mild manual pressure using several wiping strokes while carefully avoiding harsh irritating pressure.
When debriding is complete, after several gentle wiping strokes,'the user would then apply the less abrasive side of the same pad in an additional series of gentle wiping strokes. The less abrasive side of the pad would absorb dirt, oil and debris from the skin to be treated which were debrided and loosened by wiping with the pad's more abrasive side.
The foregoing dual series of wiping strokes serves the additional function of depositing upon the skin to be treated the material with which the pad was presaturated.
Typically, such material is the peeling and/or exfoliating agent of the present invention, or the degreaser composition, as more fully set forth elsewhere herein.
One of the most important novel features of the present invention derives from the fact that its concentrations of skin degreasing, exfoliating and/or moisturizing agents is drastically reduced compared to typical prior art compositions. As a consequence, the present invention produces the desired skin degreasing, exfoliating and moisturizing effects in a series of painless treatments.
Prior art professional skin peeling not done in the home has generally comprised the following sequence of steps (1) cleansing the skin; (2) application of an degreaser; (3) application of active skin peeling materials; and (4) neutralizing or removal of the active skin peeling materials.
The present invention may utilize at least one of the four steps, but with novel and very significant modifications. An alternate modification may occur in step 2 with the use of (i) acetone in a home-use skin preparation material and (ii) in the selectability of the level of applicator pad abrasiveness. The novelty of step 3 may alternatively include (i) the use of acetone as a skin penetrating agent, and (ii) the combination of a skin degreasing, exfoliating and moisturizing agent composition with a moisturizing material, which material is applied to the skin to accomplish both gradual degreasing, exfoliating and moisturizing at the same time.
In addition to the foregoing aspects of novelty, in one embodiment of the present invention, the aforementioned conventional four steps may be accomplished in a novel manner. This alternate embodiment of the present invention provides that the treatment steps be performed by applying the given material by means of a cosmetic applicator pad pre-saturated with the given material for the respective steps 1-3, the pad further being selected to provide a desired level of abrasive efficiency.
While it is known to use applicator pads of special materials and construction to apply particular skin exfoliating preparations, such as salicylic acid, the prior art does not teach the use of cosmetic applicator pads with specific abrasive capabilities, as does the present invention. According to the present invention, applicator pads with varying degrees of abrasive efficiency are selectively provided in order to further control and vary the depth of penetration of the degreasing, exfoliating and/or moisturizing agents.
A given pad abrasion level may be selected from the categories of mild and moderate abrasiveness according to the present invention. Variation in applicator pad abrasiveness is achieved by selecting suitable materials for pad construction, such as cotton, nylon, polyester, styrene and the like, singly or in combination. The pad may have an applicator surface which is of fibrous consistency or otherwise suitably textured with a blend of semi-rigid and soft materials for producing an abrasive effect for scraping, removing and degreasing action.
The penetration depth and effectiveness of the degreasing, exfoliating and/or moisturizing agents are affected by pad abrasiveness because a given level of pad abrasive capability results in mechanical exfoliation of dead skin, thus exposing underlying living skin tissue more effectively. By taking off the top layers of dead skin, the alternative skin degreaser, such as acetone, is allowed to work more effectively, providing a corresponding level of skin degreasing efficiency when the skin is wiped with the pad during the degreasing steps of treatment.
Pad abrasive efficiency thus controls the amount of natural oil and grease left upon skin which has been prepared for topical application of the degreasing, exfoliating and/or moisturizing agent. The greater the abrasive efficiency of the pad used for degreasing the skin, the deeper the degreasing, exfoliating and/or moisturizing agent will penetrate, thereby providing enhanced degreasing, exfoliating and moisturizing agent effectiveness.
The user of a pre-saturated cosmetic applicator pad for a process of at least once per day applications gains the convenience of being apply to accurately apply a quantity of each respective materials in the 3 steps. Thus predictable and desirable results are provided by the present invention, in contrast to the prior art.
When a cosmetological applicator pad is used with the composition of the present invention for use in the skin exfoliating process, the exfoliating agent is:
(a) applied to the skin;
(b) allowed to effect its exfoliating activity; and (c) debris is removed from the skin at essentially the same time while leaving the composition of the present invention on the skin to be treated.

The result is a process very convenient for the user, particularly in an at-home setting. In comparison to the present invention, the prior art teaches nothing like the application of a peeling and/or exfoliating agent which is 5 left on the skin and removal of skin cell debris.
An additional novel feature of the present invention is that the exfoliating and/or degreasing or moisturizing agents, once applied by the user, and left upon the skin for at least several hours.
10 It is not neutralized, nor is it removed, because it is a moisturizer. The present invention can be left on the skin due its low concentration of gentle exfoliating and/or moisturizing or degreasing agents. The present invention is intended to be used, preferably at night before retiring, 15 so that the exfoliating and/or moisturizing or degreasing agents would be left in contact with the user's skin until, typically, washed off by normal bathing the next morning.
The present invention can also be applied in the morning, and left on the skin all day.
In contrast, the prior art requires the application followed by the relatively quick neutralization or removal of exfoliating agents. This quick removal or neutralization is obviously necessary due to the high concentrations of exfoliating agents used in the prior art, with their attendant harshness and action deep within the skin and the wounding of living skin tissue.
Selecting the rate of skin degreasing, exfoliating and/or moisturizing during use is accomplished by varying, singly or in combination:
(a) applicator pad abrasivenss;
(b) degreaser composition, particularly with regard to the concentration of acetone therein;
(c) treatment composition containing the degreasing, exfoliating and moisturizing agents; and (d) the number and frequency of treatments involving the aforementioned steps.
It has been found that keeping the concentrations of the exfoliating and/or moisturizing agents constant, and varying the type and concentration of the alternative degreasing agent critically produces a change in the degreasing, exfoliating and/or moisturizing rate.
It is thought that this is so because a more effective degreaser, such as the alternative acetone component in the degreaser composition in relatively high concentration will be relatively more effective in removing skin surface oil, thereby more effectively exposing underlying skin to contact with the degreasing, exfoliating and moisturizing agents in the treatment composition.
Acetone has not been used in home skin treatment compositions in the prior art because it is far too harsh and produces far too much skin drying. Thus, the prior art has taught away from this critical novel feature of the present invention.
However, because of the gentle moisturizing effect of the glycolic acid in low concentrations in an applicator pad, in the alternate embodiment with acetone, the normally harsh effects of acetone are neutralized by the glycolic acid. Thus, one is able to use acetone, in spite of its harsh effects of use alone.
The degreasing, exfoliating and/or moisturizing agents thereupon penetrate the skin deeper and more effectively than if skin oils had been less efficiently removed. Also, substituting alcohol as a degreaser in place of all or a portion of acetone will affect, and thus control the rate of cleaning, since alcohol is a less efficient solvent for skin oil than is acetone. However, alcohol does not act as a skin peeling agent as does acetone.
The degreaser composition of the present invention, as elsewhere set forth, is typically a mixture of alcohol, acetone and water. The concentrations of the degreaser components in the degreaser composition can thus be varied to produce a desired rate of skin degreasing, exfoliating and moisturizing.
In preferred embodiments, the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.20 grams and about 2.0 grams, preferably between about .50 grams and about 1.0 grams.
In preferred embodiments, the unit therapeutic dose per saturated applicator pad of the peeling composition is between about 0.20 grams and about 2.0 grams, more preferably between about .50 grams to about 1.0 grams.
The present invention provides an applicator pad for treating skin conditions, such as aging skin, acne, hyperpigmentation, sensitive skin, and composite dry-oily skin. Applicator pads for the respective degreasing and/or peeling steps are respectively saturated with a quantity of degreasing, and exfoliating and/or moisturizing agents.
Each day of the course of treatment in a non-professional setting the user applies the present invention's materials at a selected frequency, for example, at least once daily, for a selected duration of treatment, for example, for a specified number of days, preferably 14 days, as indicated for each skin condition treatment as follows:
In one embodiment, the skin is degreased by the user by applying a degreaser with an applicator pad presaturated with the degreasing material. The degreasing material according to the present invention is set forth more particularly in table 3 below. In particular, the degreaser contains acetone in an aqueous base, which may also contain alcohol.
The only necessary components of the peeling/
exfoliating agent of the present invention are AHAs, or mixture thereof, of which the AHA is preferably glycolic acid, and alternatively acetone as a degreaser, exfoliant and moisturizer. The alpha hydroxy acids most effective for 17a use in the present invention are glycolic acid, which is the preferred AHA, and as well as lactic acid and pyruvic acid.
A related keto acid is also defined. These AHAs are not equivalent to each other, since glycolic acid is gentler and more effective than either lactic or pyruvic acids. In a further alternative embodiment, the addition of a small amount of salicylic acid may also be useful.
Lactic acid and pyruvic acid are harsher peeling and exfoliating agents than is glycolic acid. The use of lactic and pyruvic acids in a further alternative admixture with glycolic acid in some embodiments is a feature of the present invention, since the inclusion of lactic and/or pyruvic acids can accelerate the peeling/exfoliating action of the present invention. Other embodiments of the present invention, as set forth above, provide a AHA selected from the group consisting of glycolic, lactic and pyruvic acids and mixtures thereof.
By varying both the absolute concentrations of the 1lfins selected for a particular embodiment of the present invention, and/or selecting which AFiAs and in which particular proportions they are to be used, a precisely controlled degree of peeling/exfoliating efficacy can be achieved.
Such controlled and precise peeling/exfoliating efficacy is an important novel feature of the present invention, since variations of the present invention will permit the user to select a peeling composition which has a particular combination of speed of peeling and.harshness.
It is to be noted that while it is an feature of the present invention to provide a peel for at home use which is both gradual and gentle, it is also necessary and important to vary and to control the speed with which the present invention achieves its results. Not only can speed and efficacy be controlled as described, but speed and efficacy can also be controlled by varying the frequency of user application.
Thus, if a user doubles the frequency of application, for example, applying the present invention twice daily instead of once daily, the speed and efficacy will naturally increase. However, it is once again emphasized that rapidity of peeling action is not an object of the present invention.
'I'tie following tables describe the peeling/exfoliating compositions provided in the present invention. As has been stated, the present invention provides low-concentrations of AHAs and alternate ingredients, such as acetone and salicylic acid in a cosmetic applicator pad.
Ttie AfiAs are provided in a suitable pharmaceutical vehicle, which typically may be a composition according to the tables presented below. It will be understood that a suitable pharmaceutical vehicle is merely suggested by the non-AIIA ingredients, and that other suitable pharmaceutical veliicles wliich contain AliAs may also be used.
In the following tables, the inert, or inactive ingredients, i.e., the ingredients not set forth above as being active agents of the present invention represent the composition of a preferred pharmaceutical vehicle for the AHAs of the present invention.
Furthermore, certain tables below show representative embodiments having specific combinations of AHAs. While the preferred embodiment of the present invention provides only glycolic acid as the AHA, it has been set forth above that lactic and/or pyruvic acids may also be included singly or in combination with each other and/or in combination with glycolic acid or optionally in combination with acetone and/or salicylic acid. It will be understood that tables below specifying combinations of the aforementioned AHAs are merely exemplary and are not intended to be exclusive or to limit the scope of the present invention.
The following tables describe the peeling/exfoliating compositions provided in the present invention as well as an alternative acetone-containing degreaser composition.
As has been stated, the present invention provides low-concentrations of AHAs in a cosmetic applicator pad. The AHAs are provided in a suitable pharmaceutical vehicle, which typically may be a composition according to the tables presented below. It will be understood that a suitable pharmaceutical vehicle is merely suggested by the non-AHA ingredients, and that other suitable pharmaceutical vehicles which contain AHAs may also be used.
In the following tables, the inert, or inactive ingredients, i.e., the ingredients not set forth above as being active agents of the present invention represent the composition of a preferred pharmaceutical vehicle for the AHAs of the present invention.
Furthermore, the alternative acetone degreaser composition is separately provided in a presaturated cosmetic applicator pad to be used prior to and separately from the cosmetic applicator pad saturated with the gentle peeling and/or exfoliating composition of the present invetition.
Furthermore, certain tables below show representative enibodiments of the treatment composition having specific combitiations of AliAs, and optionally, acetone and/or salicylic acid. It has been set forth above that lactic and/or pyruvic acids may also be included singly or in combination with each other and/or in combination with glycolic acid and optionally with acetone and/or salicylic 10 acid. It will be understood that tables below specifying combinations of the aforementioned AliAs are merely exemplary and are not intended to be exclusive or to limit ttie scope of the present invention.
Table 1 Composition Showing the AHAs of the Present Invention With Non-AIIA Materials Comprising An Exemplary Preferred Pharinaceutical Vehicle Materials are listed by Weight Percentages Material From About To About 20 Disodium EDTA 0.0 0.3%
Sodium Benzoate 0.0 0.4%
Witch Iiazel E02 0.0 98%
Polysorbate-20 0.0 10%
nlptia hydroxy acid An effective amount 20%
Ammonia, dissolved 0.0 5%
*Germall 115 0.0 0.5%
Acetone 0.0 10%
Alcohol 0.0 98%
Purified Water Balance of Composition 100.0%
Table 2 Composition for Exfoliating and Moisturizing Agents of the Present Invention Showing Preferred Concentrations of AHAs Materials are listed by Weight Percentages 1-taterial Preferably From About To About Uisodium EDTA 0.080% 0.13%
Sodiuni Benzoate 0. 15 0 0. 3 0 Witch Iiazel E02 1% 5%
Polysorbate-20 0.5% 2.5%
*Trade-mark WO 94/27569 2 1 .6422 ~ PCT/US94/06443 Alpha hydroxy acid 3.0% 7.5%
Ammonia, dissolved 0.3% 1%
Germall 115 0.15% 0.3%
Acetone 0.25% 4.0%
Alcohol 2.5% 7.5%
Purified Water Balance of Composition to 100%
Table 3 Preferred Alternative Degreaser Composition Materials are listed by Weight Percentages Material From About To About Witch Hazel 0.0% 25%
Propylene Glycol 0.0% 25%
Camphor 0.0% 5%
Acetone 0.1% 10%
Alcohol 0.0% 80%
Sodium Borate 0.0% 1%
Purified Water Balance of Composition 100.0%
Table 4 Degreaser Composition Preferred Acetone Concentrations Materials are listed by Weight Percentages Preferably From About To About Witch Hazel 1% 3%
Propylene Glycol 1% 6%
Camphor 0.01% 0.75%
Acetone 1% 7%
Alcohol 30% 65%
Sodium Borate 0.01% 0.75%
Purified Water Balance to 100.0%
Tables 5-8 below show specific exemplary embodiments of the present invention. Tables 5-8 are based upon Table 1, varying only in that specific AHAs are shown and are not intended to limit the scope of the present invention.
Furthermore, preferred concentration ranges are shown in Table 2 above, and these preferred concentrations apply to Tables 5-8 below.
Table 5 Composition Showing Glycolic Acid as the AHA of the Present Invention With Non-AHA Materials Comprising An Exemplary Preferred Pharmaceutical Vehicle Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0 0.3%
Sodium Benzoate 0.0 0.4%
Witch Hazel E02 0.0 98%
Polysorbate-20 0.0 10%
Glycolic acid An effective amount 20%
Ammonia, dissolved 0.0 5%
Germall 115 0.0 0.5%
Acetone 0.0 10%
Alcohol 0.0 98%
Purified Water Balance of Composition 100.0%
Table 6 Composition Showing Glycolic Acid Admixed with Lactic Acid as an Example of an AHA Combination of the Present Invention With Non-AHA Materials Comprising An Exemplary Preferred Pharmaceutical Vehicle Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0 0.3%
Sodium Benzoate 0.0 0.4%
Witch Hazel E02 0.0 98%
Polysorbate-20 0.0 10%
Mixed glycolic and lactic acids An effective amount 20%
Ammonia, dissolved 0.0 5%
Germall 115 0.0 0.5%
Acetone 0.0 10%
Alcohol 0.0 98%
Purified Water Balance of Composition 100.0%
Table 7 Composition Showing Glycolic Acid Admixed with Pyruvic Acid as an Example of an AHA Combination of the Present Invention With Non-AHA Materials Comprising An Exemplary Preferred Pharmaceutical Vehicle Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0 0.3%
Sodium Benzoate 0.0 0.4%
Witch Hazel E02 0.0 98%
Polysorbate-20 0.0 10%
Mixed glycolic and pyruvic acids An effective amount 20%
Ammonia, dissolved 0.0 5%
Germall 115 0.0 0.5%
Acetone 0.0 10%
Alcohol 0.0 98%
Purified Water Balance of Composition 100.0%
Table 8 Composition Showing Glycolic Acid Admixed with Lactic and Pyruvic Acids as an Example of an AHA Combination of the Present Invention With Non-AHA Materials Comprising An Exemplary Preferred Pharmaceutical Vehicle Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0 0.3%
Sodium Benzoate 0.0 0.4%
Witch Hazel E02 0.0 98%
Polysorbate-20 0.0 10%
Mixed glycolic and An effective amount 20%
lactic and pyruvic acids Ammonia, dissolved 0.0 5%
Germall 115 0.0 0.5%
Acetone 0.0 10%
Alcohol 0.0 98%
Purified Water Balance of Composition 100.0%
In the degreaser composition, the concentrations of the acetone, alcohol and acetone may be varied, since the acetone is an aggressive solvent for removing residual oils on the skin and also acts as a peeling agent in its own right. The higher the acetone concentration, the more rapidly the composition of the present invention will achieve its results.
By reducing the alternative acetone concentration in relation to the relative proportions of alcohol and/or water in the degreaser, in view of the fact that neither alcohol nor water act as skin peeling agents, a gentler degreasing effect is achieved. In addition, the peeling effect of the acetone present in the degreaser will correspondingly be controlled and reduced as the acetone concentration is reduced.
Use of the present invention is accomplished by wiping with mild manual pressure a cosmetic applicator pad presaturated with at least one AHA composition over the skin to be treated. The applicator pad debrides the skin of dead skin, dead skin cell debris, dirt, and oil, all of which are removed by and remain upon the pad. As the pad is wiped across the skin to be treated, the mild manual pressure expresses the AHA composition and deposits the same topically upon the skin. Because the skin has been debrided and prepared by removal of debris dirt and oil, the AHAs are permitted access to penetrate the skin and thus to accomplish their peeling and/or exfoliating activity.
With or without an alternative first step of degreasing, as set forth above, the next step is the application to the skin of exfoliating and/or peeling material according to the present invention. The peeling agent is applied with an applicator pad presaturated therewith applied to the skin to be treated. The applicator pad is provided with a preselected level of abrasiveness selected from the group consisting of mild abrasiveness, moderate abrasiveness and strong abrasiveness.
The user exercises care in the application of moderate manual pressure to the applicator pad as it passes over the skin to be treated so as to provide a mild and/or moderate abrading of said skin.
The preferred embodiment of the composition of the present invention is presented in Table 9 below. Table 10 sets forth preferable concentrations. The preferred embodiment comprises the AHA glycolic acid combined with acetone and inert ingredients. The inert or inactive ingredients provide a suitable pharmaceutical base for the peeling agents, but do not provide a skin peeling or 5 exfoliating action. The inert ingredients may be substituted with equivalent materials for producing a suitable pharmaceutical base.
However, since the only necessary components are glycolic acid as a degreaser, exfoliant and/or moisturizer, 10 and alternatively acetone as a degreaser, the composition may be also defined as in the alternate range shown in Table 9 below, or as in an alternate preferred composition as in Table 10 below.
Table 9 15 Alternate Composition for Exfoliating and Moisturizing Agents of the Present Invention Materials are listed by Weight Percentages Material From About To About Alpha hydroxy acid An effective amount 20%
20 Acetone 0.0 10%
Alcohol 0.0 98%
Purified Water Balance of Composition to 100.0%
Table 10 Alternate Composition for Exfoliating and Moisturizing 25 Agents of the Present Invention Preferred Concentrations Materials are listed by Weight Percentages Material Preferably From About To About Alpha hydroxy acid An effective amount 7.5%
Acetone 0.0% 10%
Alcohol 0.0 98%
Purified Water Balance of Composition to 100%
The present invention provides respective kit assemblies for treating the respective skin conditions set forth above. Each respective kit assembly includes an effective and convenient instructional means, such as an instructional pamphlet or a videotape or other instructional means containing thereon indicia for administration of sequentially applied components according 21.64229 to steps needed for the respective skin condition to be treated.
The kit assembly also provides a sequential dispenser means containing a plurality of daily sets of kit sub-assembly components, such as a series of jars containing a supply of presaturated applicator pads having, respectively, cleanser, degreaser and peeling agent therein. In addition, kits are provided with containers such as bottles or tubes of other non-pad-requiring ingredients for the respective skin conditions, such non-pad-requiring materials being, for example, a moisturizer, a sun screen, etc as more fully set forth below. In addition to respective kits being specific for treatment of each aforementioned skin condition, kits are further respectively specific with regard to whether a given kit is to be used for the therapeutic phase or, in the alternative, for the maintenance phase.
Generally, and except as set forth for specific skin conditions in more detail below, each kit provided in the present invention has sub-assembly components including therein the following:
a. a step 1 container including a supply of applicator pads saturated with a premeasured quantity of a non-soaping non-detergent cleanser lotion; the supply includes two such pads for each day of intended use, one for a morning use and one for an evening use e.g., 14 step-1 pads for 7 days of intended use, for example, in the therapeutic phase.
Since the maintenance phase is intended to be used following the preferably 7-day therapeutic phase, and to provide daily maintenance treatments for one month, the corresponding maintenance kit would preferably contain 60 step-i cleansing pads for 30 days of intended twice-daily maintenance treatments. The remaining saturated pad descriptions below are similarly intended to be understood to apply, respectively to a preferably therapeutic phase of 7 days and a preferably maintenance phase of 30 days.
b. a step-2 container including a supply of applicator pads saturated with a premeasured quantity of degreaser.
c. a step-3 container including a supply of applicator pads saturated with a premeasured quantity of peeling/exfoliating exfoliating agent.
d. a step-4 container such as a tube or bottle containing a post-treatment moisturizing and anti-inflammatory material.
e. a step-5 container such as a tube or bottle containing a moisturizing sun screen material.
f. for certain skin conditions, a suitable step 6 container such as a tube or bottle with a required material, as detailed below.
Each day of the course of treatment, one component of the kit assembly is used for both applying and removing the agents in a non-professional setting according to the aforementioned steps, which are performed at selected periodic intervals, e.g., once daily by the user as directed by the instructions for the particular kit for the particular respective skin condition for the particular respective number of days of that kit's embodiment [e.g., 7-day therapy phase treatment kit for aging skin]. The step-wise procedure employed by the user is generally described in further detail as follows:
a. step 1- cleansing the skin to be treated with a non-soaping non-detergent cleanser lotion applied with an applicator pad having a preselected level of abrasiveness, said pad being wiped across the skin to be treated with mild manual pressure;
b. step 2 - applying a suitable degreasing agent to degrease the skin to be treated, the degreasing agent being applied with an applicator pad having a preselected level of abrasiveness and the pad being presaturated with a measured quantity of degreasing agent in the manner set forth in step "a";
c. step 3 - applying to the skin to be treated a composition of mild skin peeling agents of a composition elsewhere described herein, with an applicator pad presaturated with a measured quantity of said skin peeling agents in the manner set forth in step "a", the user exercising care in the application of moderate manual pressure to the applicator pad as it passes over the skin to be treated so as to provide a mild abrading of said skin; and d. step 4 - applying a suitable moisturizing anti-inflammatory cream to the skin to be treated.
e. step 5 - applying a special sun screen.
The present invention provides three types of moisturizing sun screens.
Type 1 - employs a hydro-alcoholic gel for acne patients, because this is a drying-type sun screen.
Type 2 employs a rich moisturizing sun screen for the photo aging skin and aging skin.
Type 3 - employs a bleaching agent - hydroquinone -for hyperpigmented and darkly pigmented skin.
Skin bleaching is separately provided by the present invention as a separate step for the pigmented skin, i.e., hyperpigmented skin and darkly pigmented skin. Bleaching would be done by applying a hydroquinone bleach-containing material in the evening. The hydroquinone bleach, as described in more detail below, is applied after the peeling agent has been applied and before the moisturizer is applied. Thus, the peeling/exfoliating exfoliating agent, the hydroquinone bleach, and the moisturizer are all left on the skin to be treated all night long.
The present invention provides two types of anti-inflammatory moisturizer materials. Both have hydrocortisone in them.
Type 1 - anhydrous preparation employed for aging skin.
Type 2 - hydrous preparation used for all other skin types.
The skin peeling/exfoliating exfoliating agents provided in step 3 of the present invention include low concentrations of, preferably, acetone, glycolic acid, ~~.6 4 2 2 9 salicylic acid, and lactic acid according to the Tables set forth below. In an alternate embodiment, a low-concentration quantity of resorcinol is provided as a peeling/exfoliating exfoliating agent in combination with the aforementioned preferable peeling agents. The preferred embodiment of the composition of the peeling/exfoliating exfoliating agent of the present invention is presented in Table 1 below, and the alternate embodiment composition containing resorcinol is presented in Table 2 below. Tables 1.1 and 2.1, respectively, set forth ranges and preferable concentrations for the therapeutic phase of the present invention, namely the 15-2-2 peeling/exfoliating exfoliating composition. 15-2-2 refers to preferably 15%
glycolic acid, 2% lactic acid and 2% salicylic acid. The Maintenance phase preferably utilizes 5-2-2, i.e., one-third the concentrations of the aforementioned peeling/exfoliating exfoliating agents. The compositions and concentrations of the maintenance phase peeling/exfoliating exfoliating agents are not here set forth because they are the same as those set forth in Tables 1, 1.1, 2, and 2.1, except that, instead of the 15-2-2 composition, the maintenance phase uses a 5-2-2 composition.
Table 11 Composition of Peeling/exfoliating exfoliating Agents of an Embodiment of the Therapeutic Phase of the Present Invention Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0% 0.3%
Sodium Benzoate 0.0% 1.0%
Witch Hazel E02 0.0% 20%
Polysorbate-20 0.0% 25%
Salicylic acid USP 0.1% 5%
lactic acid USP 0.1% 20%
Glycolic acid 0.1% 20%
Ammonia, dissolved 0.0% 35%
Germall 115 0.0% 1.0%

Acetone 0.1% 10%
Alcohol 0.0% 50%
Water Balance of Composition 100.0%
Table 12 Composition of Peeling/exfoliating exfoliating Agents of an Embodiment of the Therapeutic Phase of the Present Showing Preferred Concentrations Materials are listed by Weight Percentages Material Preferably About Disodium EDTA 0.1%
Sodium Benzoate 0.2%
Witch Hazel E02 2.5%
Polysorbate-20 1.0%
Salicylic acid USP 2.0%
Lactic acid USP 2.0%
Glycolic acid 15.0%
Ammonia, dissolved 6.0%
Germall 115 0.2%
Acetone 5.0%
Alcohol 5.0%
Purified Water Balance of Composition to 100%
Table 13 Composition of Peeling/exfoliating exfoliating Agents of an Alternate Embodiment of the Therapeutic Phase of the Present Invention With Resorcinol Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0% 0.3%
Sodium Benzoate 0.0% 1.0%
Witch Hazel E02 0.0% 20%
Polysorbate-20 0.0% 25%
Salicylic acid USP 0.1% 5%
Lactic acid USP 0.1% 20%
Glycolic acid 0.1% 20%
Resorcinol 0.1% 10%
Ammonia, dissolved 0.% 35%
Germall 115 0.0% 1.0%
Acetone 0.1% 10%

Alcohol 0.0% 50%
Water Balance of Composition 100.0%
Table 14 Composition of Peeling/exfoliating exfoliating Agents of an Alternate Embodiment of the Therapeutic Phase of the Present Invention With Resorcinol Same As Table 2, Showing Preferred Concentrations Materials are listed by Weight Percentages Material Preferably About Disodium EDTA 0.1%
Sodium Benzoate 0.2%
Witch Hazel E02 2.5%
Polysorbate-20 1.0%
Salicylic acid USP 2.0%
Lactic acid USP 2.0%
Glycolic acid 15.0%
Resorcinol 2.0%
Ammonia, dissolved 6.0%
Germall 115 0.2%
Acetone 5.0%
Alcohol 5.0%
Purified Water Balance to 100.0%
Table 15 Composition of Degreaser Composition of the Present Invention Materials are listed by Weight Percentages Material From About To About Witch Hazel 0.0% 25%
Propylene Glycol 0.0% 25%
Camphor 0.0% 5%
Acetone 0.1% 10%
Alcohol 1.0% 80%
Sodium Borate Trace 1%
Water Balance of Composition 100.0%
Table 16 Composition of Step 2 - Degreaser Composition of the Present Showing Preferred Concentrations Materials are listed by Weight Percentages Material Preferably About Witch Hazel 2.5%
Propylene Glycol 3.0%
Camphor 0.1%
Acetone 5.0%
Alcohol 51%
Sodium Borate 0.1%
Purified Water Balance to 100.0%
The following specific compositions are provided for treatment of the respective skin conditions. For example, in the therapy phase of acne treatment, step 1 cleanser is listed as provided in saturated pads in a 2 ounce quantity.
In like manner, all other listed component quantities are similarly divided evenly into subquantities for pad saturation for the relevant number of days.
It should be noted that, for the treatment of hyperpigmented skin and darkly pigmented skin, there are 6 steps provided, the sixth step being application of a sun screen in the morning and the fifth step being application of a moisturizer and anti-inflammatory combination in the evening. The active anti-inflammatory ingredient of the present invention is hydrocortisone. As set forth above, the individual treatments of the respective skin conditions in some cases require more than four steps. In addition, there is a separate morning and evening treatment for each respective skin condition. The individual skin conditions are treated generally as follows.
Aging and Photo-Aging Skin - Therapy Phase 1. Cleansing twice daily is accomplished with a soap-free cleansing lotion designed to cleanse efficiently without excessive drying or irritation of the skin. A
cleanser such as DEA lauryl sulfate in an emollient base and is used twice per day.
2. The degreaser is applied to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5% .

2 16 4 2' 2 9 3. 15-2-2 Treatment Pads contain the peeling/
exfoliating agent combination glycolic acid [preferably 15%, but over the possible range of 1-20%], salicylic acid [preferably 2%, but over the possible range of 0.1% to 5%], and lactic acid [preferable 2%, but over a possible range of 0.1% to 20%]. The 15-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. The peeling/exfoliating agent combination is provided in a penetrating hydro-alcoholic vehicle containing acetone as a co-solvent to insure proper delivery of the peeling/
exfoliating agent to the skin area to be treated. See Tables 1 and 2 for compositions and concentration ranges.
4. After the peeling/exfoliating treatment, the hydrocortisone balm for night-time use only is applied, containing the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the concentration range 0.1% to 2.5%, preferably 1%, in an anhydrous base.
5. A moisturizing sun screen is provided for morning application and day-time use to replenish moisture to the skin and maintain the moisture balance of the skin. The moisturizing sun screen is further provided with broad spectrum UV screens [i.e., screens for UVA and UVB] for protection from sunlight after therapy. The moisturizing sun screen contains octyl methoxycinnamate in the concentration range of 1.5% - 7.5%, preferably 7.5% and benzophenone-3 in the range from 0.1% to 6%, preferably 4%.
Aging Skin and Photo-Aging - Maintenance Phase 1. cleansing twice daily is accomplished with a soap-free cleansing lotion designed to cleanse efficiently without excessive drying or irritation of the skin. A
cleanser such as DEA lauryl sulfate in an emollient base and is used twice per day.
2. The degreaser is applied twice daily to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5%

3. Gentle twice daily peeling/exfoliation is accomplished by the use of the 5-2-2 treatment pad during the maintenance phase. The 5-2-2 pad contains glycolic acid [preferably 5%, but over a possible range of 1-20%], salicylic acid [preferably 2%, but over a possible range of 0.1% to 5%], and lactic acid [preferably 2%, but over a possible range of 0.1% to 20%]. The peeling/ exfoliating agent combination is carried in a penetrating hydro-alcoholic vehicle containing acetone in the concentration range of 0.1% to 10% but preferably 5% as a co-solvent to insure proper delivery of the peeling/ exfoliating agent to the skin area to be treated. See Tables 1 and 2 for compositions and concentration ranges.
4. After the peeling/exfoliating step, the hydrocortisone balm is applied at night time, containing the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the concentration range 0.1% to 2.5%
preferably 1% in a hydrous base.
5. A moisturizing sun screen is provided for morning application and day-time use to replenish moisture to the skin and maintain the moisture balance of the skin. The moisturizing sun screen is further provided with broad spectrum UV screens [i.e., screens for UVA and UVB] for protection from sunlight after therapy. The moisturizing sun screen contains octyl methoxycinnamate in the concentration range of 1.5% - 7.5%, preferably 7.5% and benzophenone-3 in the range from 0.1% to 6%, preferably 4%.
Sensitive Skin - Therapy Phase For sensitive skin, the therapy phase is comprised of the following steps:
1. cleansing is accomplished with a soap-free cleansing lotion designed to cleanse efficiently without excessive drying or irritation of the skin. A cleanser such as DEA lauryl sulfate in an emollient base and is used twice per day.
2. The skin is degreased gently, without excessive abrasion or further use of detergents or solvents. The skin further cleansed using ultra pure rehydrated aloe vera juice and a blend of sodium PCA and other humectants, such as methyl glyceth-20 in a water-based vehicle.
3. 15-2-2 Treatment Pads contain the peeling/exfoliating agent combination glycolic acid 5[preferably 15%, but over the possible range of 1-20%], salicylic acid [preferably 2%, but over the possible range of 0.1% to 5%], and lactic acid (preferable 2%, but over a possible range of 0.1% to 20%]. The peeling/exfoliating agent combination is provided in a penetrating hydro-10 alcoholic vehicle containing acetone as a co-solvent to insure proper delivery of the peeling/exfoliating agent to the skin area to be treated. The 15-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 15 1 and 2 for compositions and ranges.
The penetrating effect refers to the ability of the vehicle to cause deep, even dispersion throughout the skin.
A hydro-alcoholic vehicle is one containing both water and alcohol, comprising a two-solvent system.
20 4. The therapeutic balm, which is applied twice daily contains the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the range of 0.1% to 2.5% in a hydrous base. The therapeutic balm serves to promote hydration and reduce inflammation to increase user comfort, 25 as may be needed with frequent treatment of sensitive skin.
5. Moisturization and Ultraviolet light [UV]
protection is provided for morning and daytime use on sensitive skin by applying a quick absorbing oil free emulsion which is light in consistency and does not have a 30 heavy or oily base. Broad spectrum [UVA and UVB] protection is provided without the use of oxybenzone, lanolins, glycols, etc. The UV filters are Octyl Methoxycinnamate in the range of 1.5% to 7.5% and Menthyl Anthranilate in the range of 1% to 10% and the oil-free emulsion itself is a 35 water-based emulsion comprised of a water-based vehicle and an ester-based emollient phase.
Sensitive Skin - Maintenance Phase For sensitive skin, the Maintenance phase is comprised of the following:
1. Soap-free cleansing twice daily is done during the maintenance phase. Cleansing is accomplished with a soap-free cleansing lotion as in the therapy phase, the cleanser being designed to cleanse efficiently without excessive drying or irritation of the skin.
2. The skin is degreased gently twice daily, without excessive abrasion or further use of detergents or solvents. The skin further cleansed using ultra pure rehydrated aloe vera juice and a blend of sodium PCA and other humectants, such as methyl glyceth-20 in a water-based vehicle.
3. Gentle twice daily peeling/exfoliation is accomplished by the use of the 5-2-2 treatment pad during the maintenance phase. The 5-2-2 pad contains glycolic acid [preferably 5%, but over a possible range of 1-20%], salicylic acid [preferably 2%, but over a possible range of 0.1% to 5%], and lactic acid [preferably 2%, but over a possible range of 0.1% to 20%]. The peeling/ exfoliating agent combination is carried in a penetrating hydro-alcoholic vehicle containing acetone in the concentration range of 0.1% to 10% as a co-solvent to insure proper delivery of the peeling/ exfoliating agent to the skin area to be treated. The 5-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
4. After the peeling/exfoliating treatment, the therapeutic hydrocortisone balm is applied, containing the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the concentration range 0.1% to 2.5% but preferably 1%, in a hydrous base.
5. Sun protector is applied in the morning for day time use via quick absorbing, oil-free emulsion for sensitive skin. Broad spectrum [UVA and UVB] protection is provided without the use of oxybenzone, lanolins, glycols, etc. The UV filters are Octyl Methoxycinnamate in the range of 1.5% to 7.5% and Menthyl Anthranilate in the range of 1% to 10% and the oil-free emulsion itself is a water-based emulsion comprised of a water-based vehicle and an ester-based emollient phase.
Acne Treatment - Therapy Phase 1. Cleansing twice daily is accomplished with a soap-free cleansing lotion designed to cleanse efficiently without excessive drying or irritation of the skin. A
cleanser such as DEA lauryl sulfate in an emollient base and is used twice per day.
2. The degreaser is applied to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5%
3. 15-2-2 Treatment Pads contain the peeling/exfoliating agent combination glycolic acid [preferably 15%, but over the possible range of 1-20%], salicylic acid [preferably 2%, but over the possible range of 0.1% to 5%], and lactic acid [preferable 2%, but over a possible range of 0.1% to 200]. The peeling/exfoliating agent combination is provided in a penetrating hydro-alcoholic vehicle containing acetone as a co-solvent to insure proper delivery of the peeling/exfoliating agent to the skin area to be treated. The 15-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
4. A hydrocortisone moisturizer therapeutic balm is applied which is used at night time. This material uses the well-known anti-inflammatory hydrocortisone in a water-based emulsion.
5. A gel containing a topical acne preparation or group of preparations such as benzoyl peroxide is then applied in the morning, but not at night. Appropriate directions are provided in the kit of the present invention. The use of benzoyl peroxide to treat acne is well documented. This gel provides benzoyl peroxide U.S.P.
in a non-irritating water based gel.
6. An acne treatment UV screen for morning application and daytime use is provided to reduce the user's UV exposure. The acne UV screen is a non-comedogenic, oil-free preparation containing octyl methoxycinnamate in the concentration range of 1.5% - 7.5%
, preferably 7.5%; homosalate 1-10%, preferably 5%; octyl salicylate 1.5-5%, preferably 5%; and benzophenone-3 in the range from 0.1% to 6%, preferably 4% to provide broad spectrum UVA and UVB protection in a hydro-alcoholic base.
The user is instructed to use the acne UV screen liberally, i.e., to totally cover the area of therapy with the UV
screen.
Acne Treatment - Maintenance Phase 1. An antiseptic acne cleanser is provided which contains mild detergents to cleanse the skin and remove excess oil. The user is instructed to cleanse the skin at regular periodic intervals, preferably twice per day.
2. Gentle twice daily peeling/exfoliation is accomplished by the use of the 5-2-2 treatment pad during the maintenance phase. The 5-2-2 pad contains glycolic acid [preferably 5%, but over a possible range of 1-20%], salicylic acid [preferably 2%, but over a possible range of 0.1% to 5%), and lactic acid [preferably 2%, but over a possible range of 0.1% to 20%]. The peeling/exfoliating agent combination is carried in a penetrating hydro-alcoholic vehicle containing acetone in the concentration range of 0.1% to 10% as a co-solvent to insure proper delivery of the peeling/exfoliating agent to the skin area to be treated. The 5-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
3. A gel containing a topical acne preparation or group of acne preparations, such as benzoyl peroxide is then applied twice daily in the morning, and at night, as per kit instructions.

4. An acne treatment W screen for morning application and daytime use is provided to reduce the user's UV exposure. The acne UV screen is a non-comedogenic, oil-free preparation containing octyl methoxycinnamate in the concentration range of 1.5% - 7.5%
preferably 7.5%; homosalate 1-10%, preferably 5%; octyl salicylate 1.5-5%, preferably 5%; and benzophenone-3 in the range from 0.1% to 6%, preferably 4% to provide broad spectrum UVA and UVB protection in a hydro-alcoholic base.
The user is instructed to use the acne UV screen liberally, i.e., to totally cover the area of therapy with the UV
screen.
5. Evening-use Hydrocortisone Moisturizer therapeutic balm - this material uses the well-known anti-inflammatory hydrocortisone in a water-based emulsion.
Hyper Pigmented Skin and Darkly Pigmented Skin - Therapy Phase 1. Cleansing twice daily is provided by the soap-free cleanser during the maintenance phase. Cleansing is accomplished with a soap-free cleansing lotion as in the therapy phase, the cleanser being designed to cleanse efficiently without excessive drying or irritation of the skin.
2. The degreaser is applied to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5% .
3. 15-2-2 Treatment Pads contain the peeling/
exfoliating agent combination glycolic acid [preferably 15%, but over the possible range of 1-20%], salicylic acid [preferably 2%, but over the possible range of 0.1% to 5%], and lactic acid [preferable 2%, but over a possible range of 0.1% to 20%]. The peeling/exfoliating agent combination is provided in a penetrating hydro-alcoholic vehicle containing acetone as a co-solvent to insure proper delivery of the peeling/exfoliating agent to the skin area to be treated. The 15-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
4. Hydroquinone screen cream is provided for 5 application to areas of hyperpigmentation or generally to darkly pigmented skin at a selected interval, between two and four times daily, preferably three times. An alternate embodiment includes a hydro-alcoholic vehicle at night with the hydroquinone screen used in the morning. This 10 hydroquinone screen cream contains hydroquinone in the range of 0.1% to 2%, preferably 2% as a skin bleach in a non-comedogenic water based emulsion. Also provided in the hydroquinone screen cream is a broad spectrum [UVA and UVB]
sunscreen, preferably octylmethoxycinnamate, and preferably 15 about 7.5% and benzophenone-3, preferably about 1.5%. and emollients and moisturizers .
5. Therapeutic balm for night-time use. After the peeling/ exfoliating treatment, the therapeutic hydrocortisone balm is applied at night time, containing 20 the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the concentration range 0.1% to 2.5%
preferably 1% in a hydrous base.
6. Moisturization and Ultraviolet light [UV]
protection is provided for sensitive skin by applying a 25 quick absorbing oil free emulsion which is light in consistency and does not have a heavy or oily base. Broad spectrum [UVA and UVB] protection is provided without the use of oxybenzone, lanolins, glycols, etc. The UV filters are Octyl Methoxycinnamate in the range of 1.5% to 7.5% and 30 Menthyl Anthranilate in the range of 1% to 10% and the oil-free emulsion itself is a water-based emulsion comprised of a water-based vehicle and an ester-based emollient phase.
Hyper Pigmented Skin and Darkly Pigmented Skin - Maintenance Phase 35 1. Cleansing twice daily is provided by the soap-free cleanser during the maintenance phase. Cleansing is accomplished with a soap-free cleansing lotion as in the therapy phase, the cleanser being designed to cleanse efficiently without excessive drying or irritation of the skin.
2. The degreaser is applied twice daily to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5%
3. Gentle twice daily peeling/exfoliation is accomplished by the use of the 5-2-2 treatment pad during the maintenance phase. The 5-2-2 pad contains glycolic acid [preferably 5%, but over a possible range of 1-20%], salicylic acid [preferably 2%, but over a possible range of 0.1% to 5%], and lactic acid [preferably 2%, but over a possible range of 0.1% to 20%]. The peeling/exfoliating agent combination is carried in a penetrating hydro-alcoholic vehicle containing acetone in the concentration range of 0.1% to 10% as a co-solvent to insure proper delivery of the peeling/ exfoliating agent to the skin area to be treated. The 5-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
4. Hydroquinone screen cream is provided for application at a selected interval, between two and four times daily, preferably three times to pigmented areas. An alternate embodiment includes a hydro-alcoholic vehicle at night with the hydroquinone screen used in the morning.
This hydroquinone screen cream contains hydroquinone in the range of 0.1% to 2%, preferably 2% as a skin bleach in a non-comedogenic water based emulsion. Also provided in the hydroquinone screen cream is a broad spectrum [UVA and UVB]
sunscreen and emollients and moisturizers .
5. Sun protector is applied in the morning for day time use via quick absorbing, oil-free emulsion for sensitive skin. Broad spectrum [UVA and UVB] protection is provided without the use of oxybenzone, lanolins, glycols, etc. The UV filters are Octyl Methoxycinnamate in the range of 1.5% to 7.5%, preferably 7.5% and Menthyl Anthranilate ~~6.4229 in the range of 1% to 10% and the oil-free emulsion itself is a water-based emulsion comprised of a water-based vehicle and an ester-based emollient phase.
Composite Skin - Therapy Phase 1. Cleansing twice daily is provided by the soap-free cleanser during the maintenance phase. Cleansing is accomplished with a soap-free cleansing lotion as in the therapy phase, the cleanser being designed to cleanse efficiently without excessive drying or irritation of the skin.
2. The degreaser is applied twice daily to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is applied in the morning only to the areas of T-zone oiliness. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5% .
3. 15-2-2 Treatment Pads contain the peeling/exfoliating agent combination glycolic acid [preferably 15%, but over the possible range of 1-20%], salicylic acid [preferably 2%, but over the possible range of 0.1% to 5%], and lactic acid [preferable 2%, but over a possible range of 0.1% to 20%]. The peeling/exfoliating agent combination is provided in a penetrating hydro-alcoholic vehicle containing acetone as a co-solvent to insure proper delivery of the peeling/exfoliating agent to the skin area to be treated. The 15-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
4. After the peeling/exfoliating treatment, the therapeutic hydrocortisone balm is applied, containing the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the concentration range 0.1% to 2.5%, preferably 1% in a hydrous base.
5. Moisturizer and UV protection is applied via quick absorbing, oil-free emulsion for UV protection of combination skin during the day time, and is applied in the WO 94/27569 ~ 16 41229 PCT/US94/06443 morning after cleansing. Broad spectrum [UVA and UVB]
protection is provided without the use of oxybenzone, lanolins, glycols, etc. The UV filters are Octyl Methoxycinnamate in the range of 1.5% to 7.5% and Menthyl Anthranilate in the range of 1% to 10%.
Composite Skin - Maintenance Phase 1. Cleansing twice daily is provided by the soap-free cleanser during the maintenance phase. Cleansing is accomplished with a soap-free cleansing lotion as in the therapy phase, the cleanser being designed to cleanse efficiently without excessive drying or irritation of the skin.
2. The degreaser is applied twice daily to deep clean the skin and remove excess sebum, which may reduce the effectiveness of the treatment pads. The degreaser is applied in the morning only to the areas of T-zone oiliness and in the evening to the entire face or other skin area to be treated. The degreaser is a hydro-alcoholic solution containing acetone in the concentration range of 0.1% to 10% but preferably 5%
3. Gentle twice daily peeling/exfoliation is accomplished by the use of the 5-2-2 treatment pad during the maintenance phase. The 5-2-2 pad contains glycolic acid [preferably 5%, but over a possible range of 1-20%], salicylic acid [preferably 2%, but over a possible range of 0.1% to 5%], and lactic acid [preferably 2%, but over a possible range of 0.1% to 20%]. The peeling/exfoliating agent combination is carried in a penetrating hydro-alcoholic vehicle containing acetone in the concentration range of 0.1% to 10% as a co-solvent to insure proper delivery of the peeling/ exfoliating agent to the skin area to be treated. The 5-2-2 combination works synergistically with acetone as a peeling agent [preferably 5% but over the possible range of 0.1% to 10%]. See Tables 1 and 2 for compositions and concentration ranges.
4. After the peeling/exfoliating treatment, the therapeutic balm is applied in the evening, containing the well-known anti-inflammatory and anti-pruritic drug hydrocortisone in the concentration range 0.1% to 2.5%, preferably 1% in a hydrous base.
5. Sun protector is applied in the morning for day time use via quick absorbing, oil-free emulsion for sensitive skin. Broad spectrum [UVA and UVB] protection is provided without the use of oxybenzone, lanolins, glycols, etc. The UV filters are Octyl Methoxycinnamate in the range of 1.5% to 7.5% and Menthyl Anthranilate in the range of 1% to 10% and the oil-free emulsion itself is a water-based emulsion comprised of a water-based vehicle and an ester-based emollient phase.
In summary, the present invention provides a novel home skin peel composition, method and kit for producing healthy and attractive skin.
Other modifications may be made to the present invention, without departing from the spirit and scope of the present invention, as noted in the appended claims.

Claims (43)

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A skin care composition and applicator pad for gradually peeling and exfoliating skin by topical application of the skin treating composition to the skin to be treated, comprising:
a skin peeling/exfoliating composition comprising an effective concentration, said effective concentration being from about 0.1 to about 20 percent by weight of at least one alpha hydroxy acid in combination with a pharmaceutical vehicle for topical application of the peeling/exfoliating composition to skin to be treated;
wherein the skin care composition is presaturated on the applicator pad.
2. A skin care composition for gradually peeling and exfoliating skin as in claim 1, comprising at least one alpha hydroxy acid in said pharmaceutical vehicle as follows:
Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0% 0.3%
Sodium Benzoate 0.0% 0.4%
Witch Hazel E02 0.0% 98%
Polysorbate-20 0.0% 10%
Alpha hydroxy acid An Effective Amount up to about 20%
Ammonia, dissolved 0.0% 5%
*Germall 115 0.0% 0.5%
Acetone 0.0% 5%
Alcohol 0.0% 98%
Acetone 0.0% 10%
Water Balance of Composition to 100.0%.
*Trade-mark
3. The composition of claim 1, wherein the alpha hydroxy acid is comprised of a mixture of alpha hydroxy acids or alpha hydroxy acid and pyruvic acid.
4. The composition of claim 1, wherein the alpha hydroxy acid is glycolic acid.
5. The composition of claim 3, wherein the mixture includes lactic acid.
6. The composition of claim 3, wherein the mixture includes pyruvic acid.
7. The composition of claim 3, wherein the mixture includes glycolic and lactic acids.
8. The composition of claim 3, wherein the mixture includes glycolic and pyruvic acids.
9. A skin care composition and applicator pad for gradually peeling and exfoliating skin by topical application of a skin care composition to the skin to be treated, comprising, in combination:
a skin peeling/exfoliating composition comprising at least one alpha hydroxy acid in an effective concentration and a combination of inactive ingredients providing a pharmaceutical vehicle for topical application of the peeling/exfoliating composition to skin to be treated; and an abrasive cosmetic applicator pad; and wherein the skin peeling/exfoliating composition is provided presaturated in the cosmetic applicator pad for topical application to the skin to be treated.
10. The skin care composition and applicator pad of claim 9, wherein the applicator pad is an abrasive pad having two opposite sides, one of said opposite sides having relatively greater abrasiveness for debriding the skin to be treated when said greater abrasiveness side is wiped over the skin to be treated with mild manual pressure by the user; and wherein one of said opposite sides has relatively less abrasiveness for absorbing oil, dirt and debris from the skin to be treated when said less abrasive side is wiped over the skin to be treated using mild manual pressure.
11. The skin care composition and applicator pad of claim 10, wherein the side with greater abrasiveness has an abrasiveness selected from the group consisting of mild abrasiveness and moderate abrasiveness.
12. A skin care composition and applicator pad according to claim 9, wherein the skin composition comprises at least one alpha hydroxy acid in said pharmaceutical vehicle as follows:
Materials are listed by Weight Percentages Material From About To About Disodium EDTA 0.0% 0.3%
Sodium Benzoate 0.0% 0.4%
Witch Hazel E02 0.0% 98%
Polysorbate-20 0.0% 10%
Alpha hydroxy acid An Effective Amount up to about 20%
Ammonia, dissolved 0.0% 5%
*Germall 115 0.0% 0.5%
Acetone 0.0% 5%
Alcohol 0.0% 98%
Acetone 0.0% 10%
Water Balance of Composition to 100.0%.
13. The skin care composition and applicator pad of claim 12, wherein the alpha hydroxy acid is comprised of a mixture of alpha hydroxy acids or alpha hydroxy acid and pyruvic acid.
14. The skin care composition and applicator pad of claim 13, wherein the mixture includes glycolic acid.
15. The skin care composition and applicator pad of claim 13, wherein the mixture includes lactic acid.
16. The skin care composition and applicator pad of claim 13, wherein the mixture includes pyruvic acid.
17. The skin care composition and applicator pad of claim 13, wherein the mixture is comprised of glycolic and lactic acids.
18. The skin care composition and applicator pad of claim 13, wherein the mixture is comprised of glycolic and pyruvic acids.
19. The skin care composition and applicator pad of claim 13, wherein the mixture is comprised of glycolic, lactic and pyruvic acids.
20. The skin care composition and applicator pad of claim 13, wherein the mixture is comprised of lactic and pyruvic acids.
21. A method of treating a skin condition selected from the group consisting of aging skin; photo-aging skin; and dry skin; and wherein the method is comprised of a series of steps, respectively specific to the skin condition to be treated, the respective steps comprising (a) cleansing the skin to be treated; (b) degreasing the skin to be treated by applying a unit dose of a degreaser composition with an applicator pad presaturated with said degreaser composition and; (c) treatment of the skin with mild peeling and/or exfoliating agents not requiring neutralization or removal of the agents from the skin of the user, by applying a unit dose of a mild peeling and/or exfoliating agent with an applicator pad presaturated with said peeling and/or exfoliating agent; and wherein said respective steps comprise repeated user self-application of a mild, combination of skin peeling agents using an applicator pad presaturated with a respective material required for each step, and further wherein said applicator pad has an abrasiveness for applying said agents and treating the skin in a non-professional setting and wherein the peeling and/or exfoliating agents comprise at least one alpha hydroxy acid.
22. The method of claim 21, wherein cleansing the skin to be treated includes applying a non-soaping cleanser lotion by wiping the skin to be treated with an applicator pad presaturated with a measured quantity of cleanser, said pad wiping being done with mild manual pressure; and further comprising applying post-treatment compositions to the skin to be treated.
23. The method of treating skin as in claim 22, wherein the unit dose of the degreaser composition is between about 0.20 grams and about 2.0 grams of degreaser per pad wherein the peeling and/or exfoliating step is accomplished in a therapeutic phase and in an alternate maintenance phase the therapeutic phase peeling and/or exfoliating step being accomplished by applying to the skin to be treated a unit dose of a peeling and/or exfoliating material presaturated into an applicator pad and wherein the concentration of glycolic acid in said peeling and exfoliating material is from about 0.1% and 20% by weight, and the concentration of lactic acid is from about 0.1% and 20% by weight, the concentration of salicylic acid is from about 0.1% and 5% by weight; and the concentration of acetone is from about 0.1% and 10% by weight;
wherein the unit dose of the therapeutic peeling and/or exfoliating material is between about 0.20 grams and about 2.0 grams per pad and wherein the maintenance phase, peeling and/or exfoliating step is performed by applying to the skin to be treated a unit dose of a peeling and/or exfoliating material, wherein the unit dose has been presaturated into an applicator pad and the concentration of glycolic acid is from about 0.1%

to about 5% by weight, and wherein the unit dose of the maintenance peeling and/or exfoliating material is between about 0.20 grams and about 2.0 grams per pad.
24. The method of treating skin as in claim 21, wherein the peeling and/or exfoliating material contains resorcinol in an amount from about 0.1% and 10% by weight.
25. The method of treating skin as in claim 21, wherein sun screen and anti-inflammatory materials are employed in a sequence of steps following step "c".
26. The method of treating skin as in claim 23, wherein the therapeutic phase is from 5 days to 20 days in duration of daily application and the maintenance phase is from 15 days to 60 days in duration of daily application.
27. The method of method claim 26, wherein the maintenance phase is performed after the therapeutic phase.
28. The method of claim 21, wherein said applicator pad has an abrasiveness selected from the group consisting of mild abrasiveness, moderate abrasiveness and strong abrasiveness.
29. The method of claim 21, wherein said degreaser composition includes acetone in a concentration from about 0.1% to about 10% by weight.
30. A skin care kit assembly for treating a skin condition, wherein the skin condition to be treated is selected from the group consisting of aging skin, photo-aging skin, dry skin, acne, hyperpigmented skin, darkly pigmented skin, sensitive skin, thin skin, eczema and composite dry-oily skin by user repeated self-application of a combination of skin treating agents using an applicator pad for applying said agents in a non-professional setting, comprising steps performed by the user, wherein the skin treating agents require no neutralization or removal from the skin of the user, and wherein the kit comprises:

an instructional means, containing thereon indicia for administration of sequentially applied components for skin care;
a sequential dispenser means containing a plurality of daily sets of kit sub-assembly components, each kit sub-assembly component comprising:
a. a first container including a plurality of applicator pads presaturated with a unit dose of a non-soaping and/or non-detergent cleanser lotion;
b. a second container including a plurality of applicator pads presaturated with a unit dose of a degreaser composition; and c. a third container including a plurality of applicator pads presaturated with a unit dose or a composition of mild skin peeling agents, wherein said peeling agents include alpha hydroxy acid.
31. The kit as in claim 30, wherein the kit is used in accordance with a series of steps for each respective skin condition, the series of steps being in accordance with said instructional means.
32. A kit as in claim 31, wherein said sequential dispenser means includes means for dispensing daily sets of sub-assembly components including the combination of skin treating agents acting gradually over a selected period of days, for at-home use without requiring neutralization or removal from the skin of the user comprising:
a unit dose of cleaner lotion; a unit dose of a degreaser composition to be applied to skin to be treated and a unit dose of a peel and/or exfoliator composition for applying sequentially to the skin to be treated after the first degreaser composition, wherein said cleanser, degreaser and peel compositions are applied with a respective individual cosmetic applicator pad presaturated therewith, and wherein said applicator pad has a specific level of abrasiveness selected from the group consisting of mild abrasiveness, moderate abrasiveness and strong abrasiveness, and wherein the peel and/or exfoliator composition is applied to the skin to be treated after the degreaser composition, and further wherein the degreaser and peel compositions are respectively applied to the skin to be treated in a measured unit therapeutic dose, said degreaser composition comprising an aqueous composition containing from 0.1% to about 10% of acetone and said peel and/or exfoliator composition comprising an admixture of from 0.1%
to about 5% of salicylic acid, from 0.1% to about 20% of lactic acid, from 0.1% to about 20% of glycolic acid and from 0.1% to about 10% of acetone.
33. The kit as in claim 32, further comprising a unit maintenance dose of the peel and/or exfoliator composition, wherein said maintenance dose comprises concentrations of the glycolic acid, relative to the concentration of the lactic acid and salicylic acid components, respectively therein are substantially smaller than said respective concentrations in said therapeutic unit dose.
34. The kit as in claim 32, wherein the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.20 grams and about 2.0 grams and the therapeutic unit dose of the peeling composition is similarly between about 0.20 grams and about 2.0 grams.
35. The kit as in claim 34, wherein the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.50 grams and about 1.0 grams and the therapeutic unit dose of the peel and/or exfoliator composition is similarly between about 0.50 grams and about 1.0 grams.
36. The kit as in claim 33, wherein the unit maintenance dose per presaturated applicator pad of the degreaser composition is between about 0.20 grams and about 2.00 grams and the maintenance unit dose of the peel and/or exfoliator composition is similarly between about 0.20 grams and about 2.00 grams.
37. The kit as in claim 33, wherein the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.50 grams and about 1.0 grams and the therapeutic unit dose of the peeling composition is similarly between about 0.50 grams and about 1.0 grams.
38. The kit as in claim 32, wherein further the peel and/or exfoliator composition contains resorcinol.
39. The kit as in claim 38, further comprising a unit maintenance dose of the peel and/or exfoliator composition wherein said maintenance dose comprises concentrations of resorcinol which are substantially smaller than said resorcinol concentrations in said therapeutic unit dose.
40. The kit as in claim 38, wherein the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.20 grams and about 2.0 grams and the therapeutic unit dose of the peeling composition is similarly between about 0.20 grams and about 2.0 grams.
41. The kit according to claim 40, wherein the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.50 grams and about 1.0 gram and the therapeutic unit dose of the peel and/or exfoliator composition is similarly between about 0.50 grams and about 1.0 gram.
42. The kit according to claim 39, wherein the unit maintenance dose per presaturated applicator pad of the degreaser composition is between about 0.20 grams and about 2.0 grams and the maintenance unit dose of the peel and/or exfoliator composition is similarly between about 0.20 grams and about 2.0 grams.
43. The kit according to claim 39, wherein the unit therapeutic dose per presaturated applicator pad of the degreaser composition is between about 0.50 grams and about 1.0 gram and the therapeutic unit dose of the peeling composition is similarly between about 0.50 grams and about 1.0 gram.
CA002164229A 1993-06-01 1994-06-01 Skin treatment method utilizing an alpha-hydroxy acid composition and an applicator pad Expired - Fee Related CA2164229C (en)

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US7056093A 1993-06-01 1993-06-01
US7055393A 1993-06-01 1993-06-01
US08/070,553 1993-06-01
US08/070,559 1993-06-01
US08/070,559 US5505948A (en) 1993-06-01 1993-06-01 Home skin peel composition for producing healthy and attractive skin
US08/070,560 1993-06-01
US11013393A 1993-08-20 1993-08-20
US10982593A 1993-08-20 1993-08-20
US10982493A 1993-08-20 1993-08-20
US10982193A 1993-08-20 1993-08-20
US08/109,821 1993-08-20
US08/109,825 1993-08-20
US08/110,133 1993-08-20
US08/109,824 1993-08-20
PCT/US1994/006443 WO1994027569A1 (en) 1993-06-01 1994-06-01 Skin treatment method utilizing a composition and a pad

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10639252B2 (en) 2011-09-23 2020-05-05 Allergan, Inc. Compositions for skin exfoliation and use thereof

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0660720A4 (en) * 1992-09-14 1996-12-27 Walter P Smith Skin-conditioning composition, its application and manufacture.
US6103644A (en) 1993-12-22 2000-08-15 Nordico Marketing Development, Inc. Impregnated matrix and method for making same
JPH09511769A (en) * 1995-03-03 1997-11-25 エイボン プロダクツ インコーポレイテッド Non-irritating anti-acne composition
FR2732215B1 (en) * 1995-03-28 1997-04-30 Sederma Sa NEW DEPIGMENTING COSMETIC COMPOSITIONS
DE19518815A1 (en) * 1995-05-23 1996-11-28 Beiersdorf Ag Cosmetic or dermatological preparations containing alpha-hydroxy fatty acids
DE69719055T2 (en) * 1996-10-25 2003-11-27 Procter & Gamble CLEANING SUPPLIES
US6338855B1 (en) 1996-10-25 2002-01-15 The Procter & Gamble Company Cleansing articles for skin and/or hair which also deposit skin care actives
US6063397A (en) * 1996-10-25 2000-05-16 The Procter & Gamble Company Disposable cleansing products for hair and skin
US5972361A (en) * 1996-10-25 1999-10-26 The Procter & Gamble Company Cleansing products
JPH10265362A (en) * 1997-03-19 1998-10-06 Yakult Honsha Co Ltd Cosmetic
US5951991A (en) * 1997-05-22 1999-09-14 The Procter & Gamble Company Cleansing products with improved moisturization
US6280757B1 (en) 1997-05-22 2001-08-28 The Procter & Gamble Company Cleansing articles for skin or hair
US6132746A (en) * 1997-05-22 2000-10-17 The Procter & Gamble Company Cleansing products with improved moisturization
ATE550010T1 (en) 1997-09-05 2012-04-15 Procter & Gamble PREPARATIONS FOR CLEANSING AND CONDITIONING SKIN AND HAIR WITH IMPROVED DEPOSITION OF CONDITIONING INGREDIENTS
CN1191058C (en) * 1997-09-12 2005-03-02 普罗克特和甘保尔公司 Cleansing and conditioning article for skin or hair
US6294182B1 (en) 1999-03-18 2001-09-25 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Towelette product for minimizing facial fine lines and wrinkles
GB0423019D0 (en) * 2004-10-16 2004-11-17 Welfle Paul G Cosmetic kit and method
US20090017080A1 (en) * 2007-03-15 2009-01-15 Paul Robert Tanner Personal care kit having skin care compositions with a readily perceptible difference
US20080241200A1 (en) * 2007-03-30 2008-10-02 Marcy Elizabeth Sojka Cosmetic skin care system
GB0722332D0 (en) * 2007-11-14 2007-12-27 Reckitt Benckiser Uk Ltd Personal care article
IT1395928B1 (en) * 2009-09-25 2012-11-02 Skinfit Technologies S R L COSMETIC COMPOSITION IN THE FORM OF A MASK AND KIT FOR ITS PREPARATION
FR2997846B1 (en) * 2012-11-09 2023-10-20 Oreal COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND AN ACID, THE PROCESS FOR SMOOTHING KERATIN FIBERS FROM THIS COMPOSITION
DE102012222445A1 (en) * 2012-12-06 2014-06-26 Beiersdorf Ag Cosmetic or dermatological preparations containing combinations of 4-n-butylresorcinol and one or more non-terpenoid perfume raw materials
WO2016050626A1 (en) * 2014-09-29 2016-04-07 Koninklijke Philips N.V. Skin cleaning device and method
EP3226832B1 (en) 2014-12-03 2022-05-25 Mary Kay, Inc. Exfoliating cosmetic compositions

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294852A (en) * 1973-11-01 1981-10-13 Johnson & Johnson Skin treating compositions
US3984566A (en) * 1974-02-25 1976-10-05 Scott Eugene J Van Method of alleviating the symptoms of dandruff
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
US4588590A (en) * 1981-12-21 1986-05-13 Jaye-Boern Laboratories, Inc. Method of treating keratosis and compositions useful therefor
US4608370A (en) * 1985-03-04 1986-08-26 Aronsohn Richard B Skin formulation
GB8600822D0 (en) * 1986-01-15 1986-02-19 Unilever Plc Treatment of skin disorders
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents
US5091171B2 (en) * 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US4891227A (en) * 1988-02-02 1990-01-02 Richardson-Vicks Inc. Medicated cleansing pads
US4891228A (en) * 1988-02-02 1990-01-02 Richardson-Vicks Inc. Medicated cleansing pads
ES2170068T3 (en) * 1992-06-16 2002-08-01 Icn Pharmaceuticals COMPOSITION FOR SKIN TREATMENT.
NZ254632A (en) * 1992-07-27 1997-02-24 Procter & Gamble Textured laminated pad, comprising a paper layer and a synthetic fiber non-woven layer, for use in topical applications
EP0660720A4 (en) * 1992-09-14 1996-12-27 Walter P Smith Skin-conditioning composition, its application and manufacture.
US5411734A (en) * 1993-11-15 1995-05-02 Elizabeth Arden Company, Division Of Conopco, Inc. Non-irritating α-hydroxy carboxylic acid compositions
US5549888A (en) * 1994-01-31 1996-08-27 Procter & Gamble Aqueous topical anti-acne compositions of low pH

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10639252B2 (en) 2011-09-23 2020-05-05 Allergan, Inc. Compositions for skin exfoliation and use thereof

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WO1994027569A1 (en) 1994-12-08
EP0703775A1 (en) 1996-04-03

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