CA2162577A1 - Human immunoglobulin vh gene segments and dna fragments containing the same - Google Patents
Human immunoglobulin vh gene segments and dna fragments containing the sameInfo
- Publication number
- CA2162577A1 CA2162577A1 CA002162577A CA2162577A CA2162577A1 CA 2162577 A1 CA2162577 A1 CA 2162577A1 CA 002162577 A CA002162577 A CA 002162577A CA 2162577 A CA2162577 A CA 2162577A CA 2162577 A1 CA2162577 A1 CA 2162577A1
- Authority
- CA
- Canada
- Prior art keywords
- human immunoglobulin
- dna fragments
- segments
- same
- fragments containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012634 fragment Substances 0.000 title abstract 7
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 abstract 2
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
Novel human immunoglobulin V H segments and DNA
fragments containing the same are disclosed. The DNA
fragment according to the present invention is the fragment having a size of about 800 kbp which is shown in Fig. 1. The human immunoglobulin V H segments according to the present invention are contained in the fragment of this DNA fragment of about 800 kbp, and there are 50 novel segments. The base sequences of these segments are shown in the Sequence Listing. The present invention also provides DNA fragments which contain two or more of these V H segments.
fragments containing the same are disclosed. The DNA
fragment according to the present invention is the fragment having a size of about 800 kbp which is shown in Fig. 1. The human immunoglobulin V H segments according to the present invention are contained in the fragment of this DNA fragment of about 800 kbp, and there are 50 novel segments. The base sequences of these segments are shown in the Sequence Listing. The present invention also provides DNA fragments which contain two or more of these V H segments.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002162577A CA2162577C (en) | 1993-05-10 | 1993-05-10 | Human immunoglobulin vh gene segments and dna fragments containing the same |
PCT/JP1993/000603 WO1994026895A1 (en) | 1993-05-10 | 1993-05-10 | Human immunoglobulin vh gene and dna fragment containing the same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002162577A CA2162577C (en) | 1993-05-10 | 1993-05-10 | Human immunoglobulin vh gene segments and dna fragments containing the same |
PCT/JP1993/000603 WO1994026895A1 (en) | 1993-05-10 | 1993-05-10 | Human immunoglobulin vh gene and dna fragment containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2162577A1 true CA2162577A1 (en) | 1994-11-24 |
CA2162577C CA2162577C (en) | 2005-06-14 |
Family
ID=34682997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002162577A Expired - Fee Related CA2162577C (en) | 1993-05-10 | 1993-05-10 | Human immunoglobulin vh gene segments and dna fragments containing the same |
Country Status (2)
Country | Link |
---|---|
CA (1) | CA2162577C (en) |
WO (1) | WO1994026895A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000032635A3 (en) * | 1998-12-02 | 2000-08-10 | Ixsys Inc | Tumor specific human monoclonal antibodies and methods of use |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001206899A (en) * | 1999-11-18 | 2001-07-31 | Japan Tobacco Inc | HUMAN MONOCLONAL ANTIBODY AGAINST TGF-beta II TYPE RECEPTOR AND MEDICINAL USE THEREOF |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT396939B (en) * | 1990-05-29 | 1993-12-27 | Alois Dipl Ing Dr Jungbauer | COMPLEX VIRAL ANTIQUE OF HIV-1 BINDING RECOMBINANT PROTEIN |
-
1993
- 1993-05-10 CA CA002162577A patent/CA2162577C/en not_active Expired - Fee Related
- 1993-05-10 WO PCT/JP1993/000603 patent/WO1994026895A1/en active Application Filing
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000032635A3 (en) * | 1998-12-02 | 2000-08-10 | Ixsys Inc | Tumor specific human monoclonal antibodies and methods of use |
US6787638B1 (en) | 1998-12-02 | 2004-09-07 | Applied Molecular Evolution, Inc. | Tumor specific human monoclonal antibodies and methods of use |
Also Published As
Publication number | Publication date |
---|---|
WO1994026895A1 (en) | 1994-11-24 |
CA2162577C (en) | 2005-06-14 |
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CA2162577A1 (en) | Human immunoglobulin vh gene segments and dna fragments containing the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |