CA2128242A1 - Moulded Bodies, in Particular Pellets, Containing One or More Plant Extracts, and the Pharmaceutical or Cosmetic Use of Such Pellets - Google Patents
Moulded Bodies, in Particular Pellets, Containing One or More Plant Extracts, and the Pharmaceutical or Cosmetic Use of Such PelletsInfo
- Publication number
- CA2128242A1 CA2128242A1 CA 2128242 CA2128242A CA2128242A1 CA 2128242 A1 CA2128242 A1 CA 2128242A1 CA 2128242 CA2128242 CA 2128242 CA 2128242 A CA2128242 A CA 2128242A CA 2128242 A1 CA2128242 A1 CA 2128242A1
- Authority
- CA
- Canada
- Prior art keywords
- pellets
- plant extract
- plant
- gelatin
- skeleton builder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000419 plant extract Substances 0.000 title abstract 6
- 239000008188 pellet Substances 0.000 title abstract 5
- 239000002537 cosmetic Substances 0.000 title abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 3
- 229920000159 gelatin Polymers 0.000 abstract 3
- 239000008273 gelatin Substances 0.000 abstract 3
- 235000019322 gelatine Nutrition 0.000 abstract 3
- 235000011852 gelatine desserts Nutrition 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 2
- 108010035532 Collagen Proteins 0.000 abstract 2
- 108010064851 Plant Proteins Proteins 0.000 abstract 2
- 229920001436 collagen Polymers 0.000 abstract 2
- 239000000284 extract Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 235000021118 plant-derived protein Nutrition 0.000 abstract 2
- 235000002961 Aloe barbadensis Nutrition 0.000 abstract 1
- 244000186892 Aloe vera Species 0.000 abstract 1
- 108010009736 Protein Hydrolysates Proteins 0.000 abstract 1
- 235000011399 aloe vera Nutrition 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 abstract 1
- 239000007789 gas Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000003531 protein hydrolysate Substances 0.000 abstract 1
- 238000007493 shaping process Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
- A61K8/022—Powders; Compacted Powders
- A61K8/0225—Granulated powders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Shaped articles containing plant extract(s), in particular pellets, are formed by dispersing the plant extract(s) in a matrix predominantly composed of a skeleton builder, i.e. collagen, gelatin, fractionated gelatin, a collagen hydrolysate, a gelatin derivative, plant protein or plant protein hydrolysate. They are storage-stable, and their pharmacological and cosmetic characteristics are essentially unaltered in comparison with the native extract. They are prepared by a simple process in which liquid plant extract(s) is(are) mixed or emulsified in a solution of the skeleton builder, or solid extracts are dissolved or suspended in a solution of the skeleton builder, the dispersion of skeleton builder and plant extract(s) is added dropwise to an intensely cold, inert, liquefied gas, preferably liquid nitrogen, thus shaping the pellets, and the shaped pellets are dried. The plant extract employed is preferably Aloe vera juice.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4201172A DE4201172C1 (en) | 1992-01-17 | 1992-01-17 | Pellets contg. Aloe vera extract - useful, e.g. as antiinflammatory of antibiotic agents, or for treating gastric ulcers |
DE4201179A DE4201179A1 (en) | 1992-01-17 | 1992-01-17 | Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc. |
DEP4201172.8 | 1992-01-17 | ||
DEP4201179.5 | 1992-01-17 | ||
US07/876,866 | 1992-04-30 | ||
US07/876,866 US5401502A (en) | 1992-01-17 | 1992-04-30 | Pellets containing plant extracts, process of making same and their pharmaceutical peroral or cosmetic use |
US07/876,876 | 1992-04-30 | ||
US07/876,876 US5387415A (en) | 1992-01-17 | 1992-04-30 | Aloe vera juice containing pellets process for production thereof and the use thereof as pharmaceutical, cosmetic and peroral agents |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2128242A1 true CA2128242A1 (en) | 1993-07-22 |
CA2128242C CA2128242C (en) | 1998-09-22 |
Family
ID=27435368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002128242A Expired - Fee Related CA2128242C (en) | 1992-01-17 | 1993-01-18 | Moulded bodies, in particular pellets, containing one or more plant extracts, and the pharmaceutical or cosmetic use of such pellets |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0620727B1 (en) |
JP (1) | JPH07502735A (en) |
AT (1) | ATE151631T1 (en) |
AU (1) | AU679905B2 (en) |
CA (1) | CA2128242C (en) |
DE (1) | DE59306197D1 (en) |
DK (1) | DK0620727T3 (en) |
ES (1) | ES2102637T3 (en) |
GR (1) | GR3024062T3 (en) |
WO (1) | WO1993013754A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993013757A1 (en) | 1992-01-17 | 1993-07-22 | Alfatec-Pharma Gmbh | Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies |
DE19603019C2 (en) * | 1996-01-17 | 1998-10-15 | Lancaster Group Gmbh | Cosmetic skin cleanser based on natural ingredients |
IL131317A (en) * | 1999-08-09 | 2006-08-01 | Cts Chemical Ind Ltd | Binder for pharmaceutical compositions |
JP2003160440A (en) * | 2001-11-26 | 2003-06-03 | Mikimoto Pharmaceut Co Ltd | Nacreous layer powder |
EP1551373B1 (en) * | 2002-10-16 | 2014-11-12 | MedSkin Solutions Dr. Suwelack AG | Use of molded bodies for external application |
US7615245B2 (en) | 2003-04-11 | 2009-11-10 | Cargill, Incorporated | Pellet systems for preparing beverages |
WO2010009419A1 (en) * | 2008-07-18 | 2010-01-21 | Cargill, Incorporated | Frozen pellets made with juice |
EP4230187A1 (en) * | 2022-02-21 | 2023-08-23 | Biofactoria Naturae Et Salus Sa | Single-dose cosmetic product and process of manufacturing thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE454386C (en) * | 1924-05-27 | 1928-01-06 | Chemische Produkte Vormals H S | Process for the production of pharmaceutical and dietetic preparations in spherical form |
GB242323A (en) * | 1924-07-04 | 1925-11-04 | Firm Knoll & Co Chem Fab | An improved method of manufacturing medicinal jujubes |
GB887901A (en) * | 1960-04-13 | 1900-01-01 | ||
FR1397583A (en) * | 1964-05-04 | 1965-04-30 | Hoffmann La Roche | Process for the preparation of compositions containing substances sensitive to oxidation |
BE770604A (en) * | 1971-07-28 | 1971-12-01 | Hoffmann La Roche | High potency vitamin e powders |
US5215756A (en) * | 1989-12-22 | 1993-06-01 | Gole Dilip J | Preparation of pharmaceutical and other matrix systems by solid-state dissolution |
-
1993
- 1993-01-18 DK DK93902033.5T patent/DK0620727T3/da active
- 1993-01-18 JP JP5512078A patent/JPH07502735A/en active Pending
- 1993-01-18 AT AT93902033T patent/ATE151631T1/en not_active IP Right Cessation
- 1993-01-18 CA CA002128242A patent/CA2128242C/en not_active Expired - Fee Related
- 1993-01-18 DE DE59306197T patent/DE59306197D1/en not_active Expired - Lifetime
- 1993-01-18 AU AU33431/93A patent/AU679905B2/en not_active Ceased
- 1993-01-18 ES ES93902033T patent/ES2102637T3/en not_active Expired - Lifetime
- 1993-01-18 WO PCT/DE1993/000037 patent/WO1993013754A1/en active IP Right Grant
- 1993-01-18 EP EP93902033A patent/EP0620727B1/en not_active Expired - Lifetime
-
1997
- 1997-07-09 GR GR970401718T patent/GR3024062T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE59306197D1 (en) | 1997-05-22 |
AU3343193A (en) | 1993-08-03 |
DK0620727T3 (en) | 1997-05-26 |
WO1993013754A1 (en) | 1993-07-22 |
ES2102637T3 (en) | 1997-08-01 |
EP0620727B1 (en) | 1997-04-16 |
GR3024062T3 (en) | 1997-10-31 |
CA2128242C (en) | 1998-09-22 |
JPH07502735A (en) | 1995-03-23 |
EP0620727A1 (en) | 1994-10-26 |
AU679905B2 (en) | 1997-07-17 |
ATE151631T1 (en) | 1997-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |