CA2116526A1 - Therapie basee sur les recepteurs des cellules t contre l'arthrite rhumatoide - Google Patents

Therapie basee sur les recepteurs des cellules t contre l'arthrite rhumatoide

Info

Publication number
CA2116526A1
CA2116526A1 CA002116526A CA2116526A CA2116526A1 CA 2116526 A1 CA2116526 A1 CA 2116526A1 CA 002116526 A CA002116526 A CA 002116526A CA 2116526 A CA2116526 A CA 2116526A CA 2116526 A1 CA2116526 A1 CA 2116526A1
Authority
CA
Canada
Prior art keywords
beta
cell receptor
variable regions
mammal
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002116526A
Other languages
English (en)
Inventor
William V. Williams
David B. Weiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Wistar Institute of Anatomy and Biology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2116526A1 publication Critical patent/CA2116526A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
CA002116526A 1991-08-28 1992-08-27 Therapie basee sur les recepteurs des cellules t contre l'arthrite rhumatoide Abandoned CA2116526A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75091391A 1991-08-28 1991-08-28
US750,913 1991-08-28
US81791292A 1992-01-06 1992-01-06
US817,912 1992-01-06

Publications (1)

Publication Number Publication Date
CA2116526A1 true CA2116526A1 (fr) 1993-03-18

Family

ID=27115338

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002116526A Abandoned CA2116526A1 (fr) 1991-08-28 1992-08-27 Therapie basee sur les recepteurs des cellules t contre l'arthrite rhumatoide

Country Status (4)

Country Link
EP (1) EP0602178A4 (fr)
JP (1) JPH07504399A (fr)
CA (1) CA2116526A1 (fr)
WO (1) WO1993004695A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9308581D0 (en) * 1993-04-26 1993-06-09 Univ Manitoba A method for induction of antigen-specific suppression of immune-response
JPH10504181A (ja) * 1994-04-18 1998-04-28 ニューヨーク ソサエティ フォー ザ リリーフ オブ ザ ラプチャード アンド クリップルド メインティニング ザ ホスピタル フォー スペシャル サージェリー 保存されたｔ細胞レセプター配列
GB9710820D0 (en) * 1997-05-27 1997-07-23 Univ Dundee Immunological method
EP2343083B1 (fr) 2003-06-27 2014-01-15 International Institute of Cancer Immunology, Inc. Procédé de diagnostic du cancer comprenant la mesure de la fréquence de cellules précurseurs des LTC de WTI
KR101669279B1 (ko) 2007-03-05 2016-10-26 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 암 항원 특이적 ｔ 세포의 수용체 유전자 및 그것에 따라 코드되는 펩티드 및 이들의 사용
AU2013206501B2 (en) * 2007-03-05 2016-05-19 International Institute Of Cancer Immunology, Inc. Cancer antigen-specific T-cell receptor gene, peptide encoded by the gene and use of them
GB0707208D0 (en) * 2007-04-13 2007-05-23 Istituto Superiore Di Sanito Novel disease treatments
CN105968191A (zh) 2011-06-28 2016-09-28 株式会社癌免疫研究所 肽癌抗原-特异性t细胞的受体基因

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886743A (en) * 1985-04-24 1989-12-12 California Institute Of Technology Diagnostic reagents based on unique sequences within the variable region of the T cell receptor and uses thereof
FI891226A (fi) * 1988-04-28 1989-10-29 Univ Leland Stanford Junior Reseptordeterminanter i anti-t-celler foer behandling av autoimmunsjukdom.
RU2138512C1 (ru) * 1989-03-21 1999-09-27 Дзе Иммюн Риспонз Корпорейшн Вакцина для профилактики или лечения опосредованной т-клетками патологии или нерегулируемой репликации клонами т-клеток, способ выделения вакцины, способ диагностирования или прогнозирования восприимчивости к ревматоидному артриту или рассеянному склерозу, способ профилактики или лечения ревматоидного артрита или рассеянного склероза и содержащий последовательность sgdqggne пептид, являющийся агентом для обнаружения, профилактики или лечения рассеянного склероза
ES2112838T5 (es) * 1989-07-19 2004-09-01 Connetics Corporation Peptidos receptores de celulas t como agentes terapeuticos para enfermedades autoinmunitarias y malignas.
KR920703844A (ko) * 1989-11-15 1992-12-18 원본 미기재 사람에 있어 t-세포 표면 항원의 측정방법

Also Published As

Publication number Publication date
JPH07504399A (ja) 1995-05-18
EP0602178A4 (en) 1995-10-25
EP0602178A1 (fr) 1994-06-22
WO1993004695A1 (fr) 1993-03-18

Similar Documents

Publication Publication Date Title
AU635202B2 (en) Anti-t-cell receptor determinants as autoimmune disease treatment
AU672313B2 (en) Composition for preventing or treating a T cell mediated pathology
CA2064077C (fr) Peptides des recepteur des cellules t comme agents therapeutiques contre les maladies autoimmunes et les cancers
Shi et al. Promiscuous presentation and recognition of nucleosomal autoepitopes in lupus: role of autoimmune T cell receptor α chain
US6090387A (en) Vaccination and methods against diseases resulting from pathogenic responses
JP3025271B2 (ja) 無細胞ｔ細胞抗原レセプターおよびその臨床的利用
CA2188182A1 (fr) Sequences receptrices de lymphocytes t conservees
EP0722738A2 (fr) Vaccination et procédés contre des maladies issues de réponses pathogènes par des populations spécifiques de cellules T
JPH05504409A (ja) 疾病の診断および治療
US6464978B1 (en) Vaccination and methods against multiple sclerosis resulting from pathogenic responses by specific T cell populations
US6221352B1 (en) Method of preventing the proliferation of Vβ14 or Vβ17-Expressing T cells
WO1993012814A2 (fr) Vaccination et procedes contre des maladies resultant de reponses pathogenes de populations de lymphocytes t specifiques
CA2116526A1 (fr) Therapie basee sur les recepteurs des cellules t contre l'arthrite rhumatoide
US6159470A (en) Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations
AU2003237437B2 (en) T cell receptor CDR3 sequences and methods for detection
WO1999027957A1 (fr) Vaccination et procede de lutte contre la sclerose en plaques au moyen de peptides tcr vbeta specifiques
WO1998054223A2 (fr) Procede d'immunologie
US7744893B2 (en) T cell receptor CDR3 sequences associated with multiple sclerosis and compositions comprising same
AU648753C (en) Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations
AU6440999A (en) Composition for preventing or treating a T-cell mediated pathology

Legal Events

Date Code Title Description
FZDE Dead