CA2114631A1 - N-acetylglucosaminyltransferase v coding sequences - Google Patents
N-acetylglucosaminyltransferase v coding sequencesInfo
- Publication number
- CA2114631A1 CA2114631A1 CA002114631A CA2114631A CA2114631A1 CA 2114631 A1 CA2114631 A1 CA 2114631A1 CA 002114631 A CA002114631 A CA 002114631A CA 2114631 A CA2114631 A CA 2114631A CA 2114631 A1 CA2114631 A1 CA 2114631A1
- Authority
- CA
- Canada
- Prior art keywords
- glcnac
- present
- acetylglucosaminyltransferase
- specifically
- coding sequences
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
The present invention provides a substantially purified UDP-N-acetylglucosamine:.alpha.-6-D-mannoside .beta.-1,6-N-acetylgluco-saminyltransferase (GlcNAcT-V; EC 2:4.1:155) and antibodies which specifically bind GlcNAc T-V. The present invention also provides polynucleotide sequences and oligonucleotide probes capable of specifically hybridizing to nucleic acid sequences which encode GlcNAc T-V, and cDNA and genomic clones encoding GlcNAc T-V, as well as nucleotide sequences encoding GlcNAc T-V, as: specifically exemplified by, a GlcNAd T-V coding sequence from rat.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90579592A | 1992-06-29 | 1992-06-29 | |
US07/905,795 | 1992-06-29 | ||
US08/016,863 | 1993-02-10 | ||
US08/016,863 US5602003A (en) | 1992-06-29 | 1993-02-10 | N-acetylglucosaminyltransferase V gene |
PCT/US1993/006155 WO1994000475A1 (en) | 1992-06-29 | 1993-06-29 | N-acetylglucosaminyltransferase v coding sequences |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2114631A1 true CA2114631A1 (en) | 1994-01-06 |
CA2114631C CA2114631C (en) | 2005-03-01 |
Family
ID=26689155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002114631A Expired - Lifetime CA2114631C (en) | 1992-06-29 | 1993-06-29 | N-acetylglucosaminyltransferase v coding sequences |
Country Status (14)
Country | Link |
---|---|
US (2) | US5602003A (en) |
EP (1) | EP0602237B1 (en) |
JP (1) | JPH06510914A (en) |
CN (1) | CN1081205A (en) |
AT (1) | ATE173761T1 (en) |
AU (1) | AU662441B2 (en) |
CA (1) | CA2114631C (en) |
DE (1) | DE69322240T2 (en) |
DK (1) | DK0602237T3 (en) |
ES (1) | ES2125343T3 (en) |
FI (1) | FI940893A0 (en) |
GR (1) | GR3029463T3 (en) |
NO (1) | NO940655L (en) |
WO (1) | WO1994000475A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3979678B2 (en) * | 1992-08-24 | 2007-09-19 | サントリー株式会社 | Novel glycosyltransferase, gene encoding the same, and method for producing the enzyme |
US20040204381A1 (en) * | 1997-11-12 | 2004-10-14 | Moskal Joseph R | Detection and treatment of glyco-enzyme-related disease |
WO1999024584A1 (en) | 1997-11-12 | 1999-05-20 | Neurotherapeutics | Methods for the detection and treatment of disease using a glycosyltransferase |
US6897052B1 (en) * | 1998-08-07 | 2005-05-24 | Glycodesign Holdings Ltd. | N-acetylglycosaminyl transferase genes |
JP2002526037A (en) * | 1998-08-07 | 2002-08-20 | グリコデザイン インコーポレイテッド | N-acetylglycosaminyltransferase gene |
AU4343500A (en) * | 1999-04-16 | 2000-11-02 | Schering Corporation | Use of azetidinone compounds |
US7449308B2 (en) | 2000-06-28 | 2008-11-11 | Glycofi, Inc. | Combinatorial DNA library for producing modified N-glycans in lower eukaryotes |
ES2252261T3 (en) * | 2000-06-28 | 2006-05-16 | Glycofi, Inc. | METHODS TO PRODUCE MODIFIED GLICOPROTEINS. |
US8697394B2 (en) * | 2000-06-28 | 2014-04-15 | Glycofi, Inc. | Production of modified glycoproteins having multiple antennary structures |
US7598055B2 (en) * | 2000-06-28 | 2009-10-06 | Glycofi, Inc. | N-acetylglucosaminyltransferase III expression in lower eukaryotes |
US7625756B2 (en) * | 2000-06-28 | 2009-12-01 | GycoFi, Inc. | Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells |
US7863020B2 (en) * | 2000-06-28 | 2011-01-04 | Glycofi, Inc. | Production of sialylated N-glycans in lower eukaryotes |
AU2003231088B2 (en) * | 2002-04-23 | 2008-05-22 | University Of Georgia Research Foundation, Inc. | N-acetylglucosaminyltransferase Vb coding sequence, recombinant cells and methods |
US7332299B2 (en) * | 2003-02-20 | 2008-02-19 | Glycofi, Inc. | Endomannosidases in the modification of glycoproteins in eukaryotes |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5032519A (en) * | 1989-10-24 | 1991-07-16 | The Regents Of The Univ. Of California | Method for producing secretable glycosyltransferases and other Golgi processing enzymes |
JP3979678B2 (en) * | 1992-08-24 | 2007-09-19 | サントリー株式会社 | Novel glycosyltransferase, gene encoding the same, and method for producing the enzyme |
-
1993
- 1993-02-10 US US08/016,863 patent/US5602003A/en not_active Expired - Lifetime
- 1993-06-29 CN CN93107561.0A patent/CN1081205A/en active Pending
- 1993-06-29 EP EP93916824A patent/EP0602237B1/en not_active Expired - Lifetime
- 1993-06-29 JP JP6502625A patent/JPH06510914A/en active Pending
- 1993-06-29 AT AT93916824T patent/ATE173761T1/en not_active IP Right Cessation
- 1993-06-29 CA CA002114631A patent/CA2114631C/en not_active Expired - Lifetime
- 1993-06-29 DK DK93916824T patent/DK0602237T3/en active
- 1993-06-29 ES ES93916824T patent/ES2125343T3/en not_active Expired - Lifetime
- 1993-06-29 WO PCT/US1993/006155 patent/WO1994000475A1/en active IP Right Grant
- 1993-06-29 DE DE69322240T patent/DE69322240T2/en not_active Expired - Lifetime
- 1993-06-29 AU AU46546/93A patent/AU662441B2/en not_active Expired
-
1994
- 1994-02-25 FI FI940893A patent/FI940893A0/en not_active Application Discontinuation
- 1994-02-25 NO NO940655A patent/NO940655L/en unknown
- 1994-07-19 US US08/276,968 patent/US6015701A/en not_active Expired - Lifetime
-
1999
- 1999-02-19 GR GR990400552T patent/GR3029463T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU662441B2 (en) | 1995-08-31 |
GR3029463T3 (en) | 1999-05-28 |
CN1081205A (en) | 1994-01-26 |
ES2125343T3 (en) | 1999-03-01 |
FI940893A (en) | 1994-02-25 |
AU4654693A (en) | 1994-01-24 |
JPH06510914A (en) | 1994-12-08 |
US6015701A (en) | 2000-01-18 |
EP0602237A4 (en) | 1996-01-17 |
EP0602237A1 (en) | 1994-06-22 |
US5602003A (en) | 1997-02-11 |
NO940655L (en) | 1994-04-21 |
DE69322240T2 (en) | 1999-04-22 |
NO940655D0 (en) | 1994-02-25 |
FI940893A0 (en) | 1994-02-25 |
DK0602237T3 (en) | 1999-08-09 |
WO1994000475A1 (en) | 1994-01-06 |
EP0602237B1 (en) | 1998-11-25 |
DE69322240D1 (en) | 1999-01-07 |
CA2114631C (en) | 2005-03-01 |
ATE173761T1 (en) | 1998-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |