CA2113908A1 - 1-[n-(halo-3-pyridylmethyl)]-n-methylamino-1-alkylamino-2- nitroethylene derivatives for controlling fleas in domestic animals - Google Patents
1-[n-(halo-3-pyridylmethyl)]-n-methylamino-1-alkylamino-2- nitroethylene derivatives for controlling fleas in domestic animalsInfo
- Publication number
- CA2113908A1 CA2113908A1 CA002113908A CA2113908A CA2113908A1 CA 2113908 A1 CA2113908 A1 CA 2113908A1 CA 002113908 A CA002113908 A CA 002113908A CA 2113908 A CA2113908 A CA 2113908A CA 2113908 A1 CA2113908 A1 CA 2113908A1
- Authority
- CA
- Canada
- Prior art keywords
- domestic animals
- pyridylmethyl
- methylamino
- alkylamino
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Abstract
The compounds of formula I are described wherein Hal is halogen, such as fluorine, chlorine, bromine or iodine;
R1 is hydrogen, C1-C6alkyl or C3-C7cycloalkyl;
R2 is hydrogen, C1-C6alkyl or C3-C7cycloalkyl, and R3 is hydrogen or C1-C6alkyl, for use in a method of controlling fleas in domestic animals, especially in dogs and cats, wherein systemic administration is preferred. The compounds of formula I are adminis-tered in an amount effective against fleas via the digestive tract or via the blood of the host animal and thus systemically to the domestic animal, especially the dog or the cat.
R1 is hydrogen, C1-C6alkyl or C3-C7cycloalkyl;
R2 is hydrogen, C1-C6alkyl or C3-C7cycloalkyl, and R3 is hydrogen or C1-C6alkyl, for use in a method of controlling fleas in domestic animals, especially in dogs and cats, wherein systemic administration is preferred. The compounds of formula I are adminis-tered in an amount effective against fleas via the digestive tract or via the blood of the host animal and thus systemically to the domestic animal, especially the dog or the cat.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1992/001161 WO1993024002A1 (en) | 1992-05-23 | 1992-05-23 | 1-[n-(halo-3-pyridylmethyl)]-n-methylamino-1-alkylamino-2-nitroethylene derivatives for use against fleas on pets |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2113908A1 true CA2113908A1 (en) | 1993-12-09 |
| CA2113908C CA2113908C (en) | 2003-03-25 |
Family
ID=8165656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002113908A Expired - Lifetime CA2113908C (en) | 1992-05-23 | 1992-05-23 | 1-[n-(halo-3-pyridylmethyl)]-n-methylamino-1-alkylamino-2- nitroethylene derivatives for controlling fleas in domestic animals |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0616494B1 (en) |
| JP (1) | JP2783912B2 (en) |
| KR (1) | KR100236586B1 (en) |
| AT (1) | ATE171594T1 (en) |
| AU (1) | AU673329B2 (en) |
| CA (1) | CA2113908C (en) |
| DE (1) | DE59209517D1 (en) |
| DK (1) | DK0616494T3 (en) |
| ES (1) | ES2123568T3 (en) |
| FI (1) | FI107314B (en) |
| MD (1) | MD960224A (en) |
| MX (1) | MX9302936A (en) |
| NO (1) | NO306093B1 (en) |
| NZ (1) | NZ247526A (en) |
| PT (1) | PT101274B (en) |
| RU (1) | RU2106088C1 (en) |
| WO (1) | WO1993024002A1 (en) |
| ZA (1) | ZA933547B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1104198C (en) * | 1996-04-03 | 2003-04-02 | 拜尔公司 | Pesticide for parasitic insects and acarids on humans |
| US8790674B2 (en) | 2007-10-11 | 2014-07-29 | Virbac | Derivative for preparing a topical veterinary pharmaceutical composition for combating external parasites |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4414569A1 (en) * | 1994-04-27 | 1995-11-02 | Bayer Ag | Use of substituted amines for the treatment of brain disorders |
| DE4417742A1 (en) | 1994-05-20 | 1995-11-23 | Bayer Ag | Non-systemic control of parasites |
| DE4443888A1 (en) * | 1994-12-09 | 1996-06-13 | Bayer Ag | Dermally administrable formulations of parasiticides |
| EP0836851A1 (en) * | 1996-10-21 | 1998-04-22 | Virbac S.A. | Amidine compounds for use in treating ecto or endo parasitic diseases and systemic parasite control compositions |
| DE19807633A1 (en) * | 1998-02-23 | 1999-08-26 | Bayer Ag | Storage-stable water-based composition for controlling parasitic insects, especially fleas, on animals, e.g. livestock and pets |
| DK1119256T3 (en) * | 1998-10-09 | 2003-09-29 | Novartis Ag | Oral combination of lufenuron and nitenpyram against fleas |
| CO5210925A1 (en) | 1998-11-17 | 2002-10-30 | Novartis Ag | TETRASUSTITUID DIAMINUM NITROGUANIDINE DERIVATIVES |
| WO2006010767A1 (en) | 2004-07-28 | 2006-02-02 | Intervet International B.V. | Veterinary composition comprising an arylpyrazole and a nitroenamine with enhanced antiparasitic activity |
| PL2957284T3 (en) | 2007-06-27 | 2018-08-31 | E. I. Du Pont De Nemours And Company | Animal pest control method |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ221262A (en) * | 1986-08-06 | 1990-08-28 | Ciba Geigy Ag | Preventing the reinfestation of dogs and cats by fleas by administering to the host a flea growth inhibiting substance orally, parenterally or by implant |
| DE3856183T2 (en) * | 1987-08-01 | 1998-11-05 | Takeda Chemical Industries Ltd | Intermediates, their preparation and their use in the production of alpha-unsaturated amines |
| IN167709B (en) * | 1987-08-01 | 1990-12-08 | Takeda Chemical Industries Ltd | |
| US4918086A (en) * | 1987-08-07 | 1990-04-17 | Ciba-Geigy Corporation | 1-nitro-2,2-diaminoethylene derivatives |
| JP2779403B2 (en) * | 1988-11-29 | 1998-07-23 | 日本バイエルアグロケム株式会社 | Insecticidal nitro compounds |
| ES2059841T3 (en) * | 1989-02-13 | 1994-11-16 | Bayer Agrochem Kk | NITRO COMPOUNDS WITH INSECTICIDE ACTIVITY. |
-
1992
- 1992-05-23 DK DK92917460T patent/DK0616494T3/en active
- 1992-05-23 MX MX9302936A patent/MX9302936A/en unknown
- 1992-05-23 AT AT92917460T patent/ATE171594T1/en active
- 1992-05-23 MD MD96-0224A patent/MD960224A/en unknown
- 1992-05-23 DE DE59209517T patent/DE59209517D1/en not_active Expired - Lifetime
- 1992-05-23 KR KR1019940700181A patent/KR100236586B1/en not_active IP Right Cessation
- 1992-05-23 EP EP92917460A patent/EP0616494B1/en not_active Expired - Lifetime
- 1992-05-23 CA CA002113908A patent/CA2113908C/en not_active Expired - Lifetime
- 1992-05-23 AU AU18746/92A patent/AU673329B2/en not_active Expired
- 1992-05-23 RU RU94045152A patent/RU2106088C1/en active
- 1992-05-23 ES ES92917460T patent/ES2123568T3/en not_active Expired - Lifetime
- 1992-05-23 WO PCT/EP1992/001161 patent/WO1993024002A1/en active IP Right Grant
- 1992-05-23 JP JP4510118A patent/JP2783912B2/en not_active Expired - Fee Related
-
1993
- 1993-04-30 NZ NZ247526A patent/NZ247526A/en not_active IP Right Cessation
- 1993-05-21 PT PT101274A patent/PT101274B/en not_active IP Right Cessation
- 1993-05-21 ZA ZA933547A patent/ZA933547B/en unknown
-
1994
- 1994-01-20 NO NO940199A patent/NO306093B1/en not_active IP Right Cessation
- 1994-01-21 FI FI940324A patent/FI107314B/en not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1104198C (en) * | 1996-04-03 | 2003-04-02 | 拜尔公司 | Pesticide for parasitic insects and acarids on humans |
| US8790674B2 (en) | 2007-10-11 | 2014-07-29 | Virbac | Derivative for preparing a topical veterinary pharmaceutical composition for combating external parasites |
Also Published As
| Publication number | Publication date |
|---|---|
| AU673329B2 (en) | 1996-11-07 |
| EP0616494A1 (en) | 1994-09-28 |
| RU2106088C1 (en) | 1998-03-10 |
| NO940199D0 (en) | 1994-01-20 |
| JP2783912B2 (en) | 1998-08-06 |
| ATE171594T1 (en) | 1998-10-15 |
| EP0616494B1 (en) | 1998-09-30 |
| ZA933547B (en) | 1993-11-23 |
| MD960224A (en) | 1999-01-31 |
| AU1874692A (en) | 1993-12-30 |
| ES2123568T3 (en) | 1999-01-16 |
| PT101274A (en) | 1994-03-31 |
| CA2113908C (en) | 2003-03-25 |
| NO306093B1 (en) | 1999-09-20 |
| MX9302936A (en) | 1993-11-01 |
| PT101274B (en) | 1999-10-29 |
| NZ247526A (en) | 1996-09-25 |
| FI940324A0 (en) | 1994-01-21 |
| JPH06508824A (en) | 1994-10-06 |
| DK0616494T3 (en) | 1999-06-21 |
| KR100236586B1 (en) | 2000-03-02 |
| WO1993024002A1 (en) | 1993-12-09 |
| DE59209517D1 (en) | 1998-11-05 |
| FI940324A (en) | 1994-01-21 |
| IE930390A1 (en) | 1993-12-01 |
| FI107314B (en) | 2001-07-13 |
| NO940199L (en) | 1994-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |