CA2109516A1 - Inhibitors of cathepsin g and elastase for preventing connective tissue degradation - Google Patents

Inhibitors of cathepsin g and elastase for preventing connective tissue degradation

Info

Publication number
CA2109516A1
CA2109516A1 CA002109516A CA2109516A CA2109516A1 CA 2109516 A1 CA2109516 A1 CA 2109516A1 CA 002109516 A CA002109516 A CA 002109516A CA 2109516 A CA2109516 A CA 2109516A CA 2109516 A1 CA2109516 A1 CA 2109516A1
Authority
CA
Canada
Prior art keywords
cathepsin
elastase
inhibitors
connective tissue
tissue degradation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002109516A
Other languages
French (fr)
Other versions
CA2109516C (en
Inventor
Michael R. Angelastro
Philippe Bey
Niall S. Doherty
Michael J. Janusz
Shujaath Mehdi
Norton P. Peet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/704,449 external-priority patent/US5182612A/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1992/003288 external-priority patent/WO1992020357A1/en
Publication of CA2109516A1 publication Critical patent/CA2109516A1/en
Application granted granted Critical
Publication of CA2109516C publication Critical patent/CA2109516C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel compounds which are chemically linked inhibitors of the proteases Elastase and Cathepsin G prevent connective tis- sue degradation associated with neutrophil induced inflammatory disease.</SD OAB>
CA002109516A 1991-05-23 1992-04-21 Inhibitors of cathepsin g and elastase for preventing connective tissue degradation Expired - Fee Related CA2109516C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/704,449 US5182612A (en) 1990-05-23 1991-05-23 Method of measurement of an angle of incidence of a luminous beam, measuring device for carrying out the method and use of the device for the measurement of distances
US704,499 1991-05-23
PCT/US1992/003288 WO1992020357A1 (en) 1991-05-23 1992-04-21 Inhibitors of cathepsin g and elastase for preventing connective tissue degradation

Publications (2)

Publication Number Publication Date
CA2109516A1 true CA2109516A1 (en) 1992-11-24
CA2109516C CA2109516C (en) 2003-02-11

Family

ID=24829535

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002109516A Expired - Fee Related CA2109516C (en) 1991-05-23 1992-04-21 Inhibitors of cathepsin g and elastase for preventing connective tissue degradation

Country Status (2)

Country Link
KR (1) KR100230541B1 (en)
CA (1) CA2109516C (en)

Also Published As

Publication number Publication date
KR100230541B1 (en) 1999-11-15
CA2109516C (en) 2003-02-11

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20050421