CA2086225A1 - Detergent compositions comprising nonionic glycolipid surfactants - Google Patents

Abstract

C6171c2 ABSTRACT

The invention relates to detergent compositions suitable for cleaning fabrics or hard surfaces, and comprising a nonionic glycolipid surfactant which is an aldobionamide.

Description

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DETERGENT C~MPOSITIONS
COMPRISING NONIONIC GLYCOLIPID SURFACTANTS

BACKGROUND OF IHE INVENTION

The present invention relates to novel detergent compositions suitable for cleaning fabrics and hard surfaces. ~he compositions of the invention comprise glycolipid surfactants, and in particular comprise nonionic aldobionamides as surface active agents.

An aldobionamide is defined as the amide of an aldobionic acid (or aldobionolactone) and an aldobionic - acid in turn is defined as a sugar substance ~eg any cyclic sugar) in which the aldehyde group (generally found at the C1 position on the sugar) has been replaced by a carboxylic acid. Aldonamides may be based on compounds comprising one saccharide unit ~eg gluconamide), two saccharide units, teg lactobionamide or maltobionamide) or they may be based on compounds compromising more than two saccharide units as long as the polysaccharide has a terminal sugar unit with an aIdehyde group available.

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There must, however, be at least two saccharide units because these materials pack less closely in the solid state making them more water-soluble than a linear saccharide (eg a gluconamide or glucoheptonamide), thereby allowing a stable composition to form.

Most surfactants presently used in detergent compositions are based on petrochemicals. Because of increased concern over environmental issues raised by use of petrochemicals and also because of the continually rising costs of these petrochemicals, it would be useful to develop surfactants which are instead derived from carbohydrates. These natural occurring compounds represent a source of renewable raw materials that are synthetically versatile, inexpensive, optically pure, and environmentally friendly.

US 2 752 334 (Walton) teaches compounds which are the reaction products of aldonic acids (eg lactobionic acid) and fatty amines. The compound is said to be useful as an emulsifier in food compositions.

In Williams et al., Archives of Biochem. and Biophysics, 195(1):145-151 (1979), there is described glycolipids prepared by linking aldobionic acids to alkylamine through an amide bond. Although it is said that these compounds, like all surfactants, form micelles, there is no teaching or suggestion of the use of these compounds in detergent compositions.
US 5 009 814 teaches N-polyhydroxyalkyl fatty acid amides used as thickeners in aqueous surfactant systems having the formula 2 ~

- 3 - C6171 ~1 .
X-CH2N-C-Rl wherein Rl is alkyl, R2 is hydrogen, alkyl or alkyl hydroxide and X is a polyhydroxy group.

This is a completely different class of compounds from the aldobionamides of the invention. In the compounds disclosed, the polyhydroxy group is separated by a methylene group attached to the nitrogen atom rather than the carbonyl group resulting in an amide linkage that is reversed compared to the compounds of the invention. These compounds are prepared by the reaction of a monosaccharide suger amine with an alkyl ester of a fatty acid, whereas the aldobionamides o~ this invention are prepared by the reaction of disaccharide (or greater) sugar lactones with a fatty amine.

In addition, there is a series of Procter and Gamble patent applications teaching a number of compositions which comprise polyhydroxy amide. W0-92/06172A, for example, teaches built liquid detergent compositions containing polyhydroxy acid amide. There are at least 20 other patent applications reciting various compositions containing the same polyhydroxy amide.

The polyhydroxy amide of each of these references is, like the compound of US 5 009 814, a co~pletely different compound from the aldobionamides of the invention. Again, the hydroxy group in each case is separated by a methylene group attached to the nitrogen atom rather than the carbonyl group.

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2~8~22a

- 4 - C6171 FR 2 523 962 (Monsigny) teaches linear amides having the formula:

HOCH2(CHOH)mCONHR

in which m is 2 to 6 and R is a linear or branched alkyl group having 6 to 18 carbons. The e surfactants are said to be low foaming and must be ethoxylated or propoxylated by typical means for sufficient solubility.

The reference fails to teach the aldobionamides of the invention. Aldobionamides do not pack as closely in the solid state as aldonamides and are therefore more soluble (lower Krafft point) and higher foaming. To the extent that the reference teaches low foaming (suggesting low solubility and high Kra~ft point), the reference not only fails to teach or suggest the aldobionamides of the sub~ect invention, but actually teaches away.
Accordingly, it would be greatly desirable to find carbohydrates, in particular aldobionamides, which can be successfully used as surfactants in detergent compositions.

DEFINITION OF THE INVENTION

The present invention accordingly provides a detergent composition suitable for cleaning fabrics or hard surfaces, comprising a nonionic glycolipid surfactant which is an aldobionamide.

2~2~
_ 5 _ C6171 The aldobionamides with w~ich the invention are concerned generally have the formula ANRlR2 wherein A is a sugar moiety which is an aldobionic acid except that it does not contain the OH group normally extending from the carbonyl group on the aldobionic acid;
NRlR2 is attached where the hydroxyl group on the aldobionic acid would normally be found: and Rl and R2 are the same or different and are selected from the group consisting of hydrogen, aliphatic hydrocarbons, aromatic radicals, cycloaliphatic radicals, amino acid esters, ether amines, and mixtures thereof, except that Rl and R2 cannot be hydrogen at the same time.
In preferred compositions according to the invention the aldobionamide is one in which R i8 hydrogen and Rl is an alkyl group having from 8 to 24 carbon atoms.

In preferred compounds, A is a disaccharide sugar group forming the compound which is an aldobionic acid except for the OH group.

DETAILED DESCRIPTION OF THE INVENTION

The present invention relates to the use of personal product or detergent compositions comprising environmentally friendly surfactants, in particular environmentally friendly nonionic surfactants, such as aldobionamides.

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Aldobionamides are defined as the amide of an aldobionic acid (or aldobionolactone) and an aldobionic acid is a sugar substance (eg any cyclic sugar comprising at least two saccharide units) wherein the aldehyde group ~generally found at the Cl position of the sugar) has been replaced by a carboxylic acid, which upon drying cyclises to an aldobionolactone.

An aldobionamide may be based on compounds comprising two saccharide units (eg lactobionamides or maltobionamides from the aldobionamide bonds), or they may be based on compounds comprising more than two saccharide units, as long as the terminal sugar in the polysaccharide has an aldehyde group. By definition an aldobionamide must have at least two saccharide units and cannot be linear. Disaccharide compounds such as lactobianomides or maltcbionamides are preferred compounds. Other examples o~ aldobionamides (disaccharides) which may be used include cellobionamides, melibionamides and gentiobionamides.

A specific example of an aldobionamide which may be used for purposes of the invention is the disaccharide lactobionamide set forth below:

,~OH ~
3 o ~ N~ z pH ~) HO~O~¦

OH

- 2i~862~
_ 7 _ C6171 wherein Rl and R2 are the same or different and are selected from the group consisting of hydrogen: an aliphatic hydrocarbon radical (eg alkyl groups and alkene groups which groups may contain heteroatoms such as N, O
or S or alkoxylated alkyl chains such as ethoxylated or propoxylated alkyl groups), preferably an alkyl group having 8 ~o 24, preferably 10 to 18 caxbons; an aromatic radical (including substituted or unsubstituted aryl groups and arenes); a cycloaliphatic radical; an amino acid ester, ether amines and mixtures thereof, except that Rl and R2 cannot be hydrogen at the same time.

Another preferred aldobionamide is maltobionamide of the following formula:

~ r HO ~ O OH
HO ~ 2 ~ OH

wherein Rl and R2 are the same or different and are selected from the group consisting of hydrogen, aliphatic hydrocarbons, aromatic radicals, cycloaliphatic radicals, amino acid esters, ether amines, and mixtures thereof, except that Rl and R2 cannot be hydrogen at the same time.

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Suitable aliphatic hydrocarbon radicals include saturated and unsaturated radicals including but not limited to methyl, ethyl, amyl, hexyl, heptyl, nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, and octadecyl, and allyl, undecenyl, oleyl, linoleyl, linolenyl, propenyl, and heptenyl.

Aromatic radicals are exemplified, for example, by benzyl.

Suitable mixed aliphatic aromatic radicals are exemplified by benzyl, phenyl ethyl, and vinyl benzyl.

Cycloaliphatic radicals are exemplified by cyclopentyl and cyclohexyl.

The aldobionamides used in the composition of the invention have been found to have properties (ie critical micelle concentrations; Krafft point; foaming;
detergency) indicating that they are equal to or better than other well known nonionic surfactants which are based on petrochemicals (eg alkoxylated surfactants from the Neodol (Trade Mark) series from Shell), thereby indicating that they can be a viable, environmentally friendly alternative to the use of more traditional nonionic surfactants.

While not wishing to be bound by theory, it is believed that the lower solubility of the aldobionamide is due to the sugar structure which prevents the close packing which occurs in linear monosaccharide aldonamides such as gluconamides. The greater number of hydroxyl groups also probably helps to make the aldobionamides more soluble.

2~h ~3 - g - C6171 In addition, the surfactants of the invention may be used as cosurfactants with other nonionic surfactants, in particular ethoxylated alcohol nonionic surfactants, or with other surfactants (eg cationic, anionic, zwitterionic, amphoteric) used in detergent formulations.

DETERGENT COMPOSITIONS

The aldobionamide surfactants may be used in cleansing or detergent compositions for fabrics or for hard surfaces.

Examples of liquid detergent compositions are described in US 4 959 179 (Aronson et al). hereby incorporated by reference into the subject application;
and examples of powdered detergent compositions are described in US 4 929 379 (Oldenburg et al), hereby incorporated by reference into the sub~ect application.
The liquid detergent compositions of the invention may be built or unbuilt and may be aqueous or nonaqueous.
The compositions generally comprise about 5-70% by weight of a detergent active material and from 0 to 50 wt~ of a builder. The liquid detergent compositions of the invention may further comprise an amount of electrolyte (defined as any water-soluble salt) whose quantity depends on whether or not the composition is structured.
By structured is meant the formation of a lamellar phase sufficient to endow solid suspending capability.

Nore particularly, while no electrolyte is reguired for a non-structured, non-suspending composition, at least 1%, more preferably at least 5~ by weight and most preferably at least 15% by weight electrolyte is used.

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The formation of a lamellar phase can be detected by means well known to those skilled in the art.

The water-soluble electrolyte salt may be a detergency builder, such as the inorganic salt sodium tripolyphosphate or it may be a non-functional électrolyte such as sodium sulphate or chloride.
Preferably, whatever builder is used in the composition comprises all or part of the electrolyte.

The liquid detergent composition generally further comprises enzymes such as proteases, lipases, amylases and cellulases which, when present, may be used in amounts from 0.01 to 5% of the compositions. Stabilisers or stabiliser systems may be used in conjunction with enzymes and generally comprise from 0.1 to 15% by weight of the composition.

The enzyme stabilisation system may comprise calcium ion, boric acid, propylene glycol and/or short chain carboxylic acids. The composition preferably contains from 0.01 to 50, preferably from 0.1 to 30, more preferably from 1 to 20 millimoles of calcium ion per litre.
When calcium ion is used, the level of calcium ion should be selected so that there is always some minimum level available for the enzyme after allowing for complexation with builders, etc., in the composition.
Any water-soluble calcium salt can be used as the source of calcium ion, including calcium chloride, calcium formate, calcium acetate and calcium propionate. A small amount of calcium ion, generally from 0.05 to 2.5 millimoles per litre, is often also present in the composition due to calcium in the enzyme slurry and formula water.

2 ~

~ C6171 Another enzyme stabiliser which may be used is propionic acid or a propionic acid salt capable of forming propionic acid. When used, this stabiliser may be used in an amount from 0.1 to 15% by weight of the composition.

Other preferred enzyme stabilisers are polyols containing only carbon, hydrogen and oxygen atoms. They preferably contain from 2 to 6 carbon atoms and from 2 to 6 hydroxy groups. Examples include propylene glycol (especially 1,2 propanediol which is preferred), ethylene glycol, glycerol, sorbitol, mannitol and glucose. The polyol generally repre~ents from 0.5% to 15%, preferably from 1.0 to 8% by weight of the composition.
The composition herein may also optionally contain from 0.25 to 5 wt%, most preferably from 0.5 to 3% by weight of boric acid. The boric acid may be, but i5 preferably not, formed by a compound capable of forming boric acid in the composition. Boric acid is preferred, although other compounds such as boric oxide, borax and other alkali metal borates (e.g. sodium ortho-, meta- and pyroborate and sodium pentaborate) are suitable.
Substituted boric acids (for example, phenylboronic acid, butane boronic acid and a p-bromo phenylboronic acid) can also be used in place of boric acid.

On especially preferred stabilisation system is a polyol in combination with boric acid. Preferably, the weight ratio of polyol to boric acid added is at least 1, more preferably at least about 1.3.

With regard to the detergent active, the detergent active material may be an alkali metal or alkanolamine 3S soap or a 10 to 24 carbon atom fatty acid, including polymerised fatty acids, or an anionic, a nonionic, ' ~ ' . ~ , '.

2~22~

cationic, zwitterionic or amphoteric synthetic detergent material, or mixtures of any of these.

Examples of the anionic synthetic detergents are salts (including sodium, potassium, a~monium and substituted ammonium salts) such as mono-, di- and triethanolamine salts of 9 to 20 carbon alkylbenzenesulphonates, 8 to 22 carbon primary or secondary alkanesulphonates, 8 to 24 carbon olefinsulphonates, sulphonated polycarboxylic acids prepared by sulphonation of the pyrolyzed product of alkaline earth metal citrates, for example, as described in GB 1 082 179, 8 to 22 carbon alkylsulphates, 8 to 24 carbon alkylpolyglycol-ether-sulphates, -carboxylates and -phosphates (containing up to 10 moles of ethylene oxide); further examples are described in "Surface Active Agents and Detergents" (vol. I and II) by Schwartz, Perry and Berch. Any suitable anionic may be used and the examples are not intended to be limiting in any way.
Examples of nonionic synthetic detergents which may be used with the invention are the condensation products of ethylene oxide, propylene oxide and/or battalion oxide with 8 to 18 carbon alkylphenols, 8 to 18 carbon fatty acid amides; further examples of nonionics include tertiary amine oxides with 8 to 18 carbon alkyl chain and - two 1 to 3 carbon alkyl chains. The above reference also describes f~rther examples of nonionics.

The average number of moles of ethylene oxide and/or propylene oxide present in the above nonionics varies from 1-30; mixtures of various nonionics, including mixtures of nonionics with a lower and a higher degree of alkoxylation, may also be used.

2~2~5 Examples of cationic detergents which may be used are the quaternary ammonium compounds such as alkyldimethylammonium halogenides.

Examples of amphoteric or zwitterionic detergents which may be used with the invention are N-alkylamine acids, sulphobetaines, condensation products of fatty acids with protein hydrolysates; but owing to their relatively high costs they are usually used in combination with an anionic or a nonionic detergent.
Mixtures of the various types of active detergents may also be used, and preference is given to mixtures of an anionic and a nonionic detergent active. Soaps (in the form of their sodium, potassium and substituted ammonium salts) of fatty acids may also be used, preferably in conjunction with an anionic and/or nonionic synthetic detergent.

Builders which can be used according to this invention include conventional alkaline detergency builders, inorganic or organic, which can be used at levels from 0 to 50% by weight of the composition, preferably from 1 to 20% by weight, most preferably from 2 to 8%.
Examples of suitable inorganic alkaline detergency builders are water-soluble alkalimetal phosphates, polyphosphate, borates, silicates and also carbonates.
Specific examples of such salts are sodium and potassium triphosphates, pyrophosphates, orthophosphates, hexametaphosphates, tetraborates, silicates and carbonates.

Examples of suitable organic alkaline detergency builder salts are: (1) water-soluble amino polycarboxylates, for example, sodium and potassium . . .
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2 2 .~

ethylenediaminetetraacetates, nitrilotriacetates and N-(2 hydroxyethyl)-nitrilodiacetates; (2) water-soluble salts of phytic acid, for example, sodium and potassium phytates ~see US 2 379 942); (3) water-soluble polypho~phonates, including specifically, sodium, potassium and lithium salts of ethane-l-hydroxy-l,ldiphosphonic acid; sodium, potassium and lithium salts of methylene diphosphonic acid: and sodium, potassium and lithium salts of ethane-1,1,2-triphosphonic acid. Other examples include the alkali methal salts of ethane-2-carboxy-1,1-diphosphonic acid hydroxymethanediphosphsnic acid, carboxylidiphosphonic acid, ethane-l-hydroxy-1,1,2-triphosphonic acid, ethane-2-hydroxy-1,1,2-triphosphonic acid, propane-1,1,3,3-tetraphosphonic acid, propane-1,1,2,3-tetraphosphonic acid, and propane-l~2~2~3-tQtrapho~phonic acid: (4) water 601uble salts of polycarboxylate polymers and copolymers as described in US 3 308 067.

In addition, polycarboxylate builders can be used satisfactorily, including water-soluble salts of mellitic acid, citric acid, and carboxymethyloxysuccinic acid and salts of polymers of itaconic acid and maleic acid.
Other polycarboxylate builders include DPA (dipicolinic acid) and ODS (oxydisoccinic acid). Certain zeolites or aluminosilicates can be used. one such aluminosilicate which is useful in the compositions of the invention is an amorphous water-insoluble hydrated compound of the formula Nax(A102.SiO2jy, wherein x is a number from 1.0 to 1.2 and y is 1, said amorphous material being further characterised by a Mg++ exchange capacity of from about 50mg eq. CaCo3/g. and a particle diameter of from 0.01 micron to 5 microns. This ion exchange builder is more fully described in GB 1 470 250 (Procter & Gamble).

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- 15 - c6171 A second water-insoluble synthetic aluminosilicate ion exchange material useful herein is crystalline in nature and has the formula Naz ~(A102)y~(SiO2)].XH20, wherein z and y are integers of at least 6: the molar ratio of z and y is in the range from 1.0 to 0.5, and x is an integer from 15 to 264; said aluminosilicate ion exchange material having a particle size diameter from 0.1 micron to 100 microns; a calcium ion exchange capacity on an anhydrous basis of at least 200 milligrams equivalent of CaC03 hardness per gram; and a calcium exchange rate on an anhydrous basis of at least 2 grains/gallon/minute/gram. These synthetic aluminosilicates are more fully described in GB 1 429 143 (Procter h Gamble).
In addition to the ingredients described hereinbefore, the pre~erred compositions herein may frequently contain a series o~ optional ingredients which are used for the known functionality in conventional levels. While the detergent compositions are generally premised on aqueous, enzyme-containing detergent compositions, it is frequently desirable to use a phase regulant. This component together with water constitutes then the solvent matrix for the claimed liquid compositions. Suitable phase regulants are well-known in liquid detergent technology and, for example, can be represented by hydrotropes such as salts of alkylarylsulphonates having up to 3 carbon atoms in the alkyl group, for example, sodium, potassium, ammonium and ethanolamine salts of xylene-, toluene-, ethylbenzene-, cumene-, and isopropylbenzene sulphonic acids. Alcohols may also be used as phase regulants. This phase regulant is frequently used in an amount from 0.5 to 20 wt%, the sum of phase regulant and water normally being in the range of from 35 to 65wt%.

- '~08~225 The preferred compositions herein can contain a series of further optional ingredients which are mostly used in additive levels, usually below 5 wt%. Examples of the like additives include: polyacids, suds regulants, opacifiers, antioxidants, bactericides, dyes, perfumes, brighteners and the like.

The beneficial utilisation of the claimed compositions under various usage conditions can require the utilisation of a suds regulant. While generally all detergent suds regulants can be utilised, preferred for use herein are alkylated polysiloxanes such as dimethylpolysiloxane, also frequently termed silicones.
The silicones are frequently used in a level not exceeding 0.5 wt%, most preferably from 0.01 to 0.2 wt%.

It can also be desirable to utilise opacifiers inasmuch as they contribute to create a uniform appearance of the concentrated liquid detergent compositions. Examples of suitable opacifiers include:
polystyrene commercially known as LYTRON (Trade Mark) 621 manufactured by Monsanto Chemical Corporation. ~he opaci*iers are frequently used in an amount from 0.3 to 1.5 wt%.
The compositions herein can also contain known antioxidants for their known utility, frequently radical scavengers, in the art established levels, ie 0.001 to 0.25 wt% (by reference to total composition). These antioxid~nts are frequently introduced in conjunction with fatty acids.

Liquid detergent compositions of the invention may also contain deflocculating polymers such as described in US 5 071 586 (Tever Brothers Company) hereby incorporated by reference.

--`` 2 ~ 7 ~:i When the liquid composition is an aqueous composition, the balance of the formulation consists of an aqueous medium. When it is in the form of a nonaqueous composition, the above ingredients make up for the whole formulation ~a nonaqueous composition may contain up to 5 wt% water).

An ideal liquid detergent composition might contain (all percentages by weight):

(1) 5-70% detergent active system;
(2) 0-50% builder;
(3) 0-40% electrolyte (4) 0.01-5% enzyme:

(5) 0.1-15% enzyme stabiliser;

(6) 0-20% phase regulant: and

(7) remainder water and minors The detergent compo6ition o~ the invention might also be a powdered detergent composition.

Such powdered compositions generally comprise from 5 to 40 wt% of a detergent active system which generally consists of an anionic, a nonionic active, a fatty acid soap or mixtures thereof: from 20-70% of an alkaline buffering agent: up to 60 wt% of builder, preferably 10 to 60 wt% and preferably up to 40 wt%; and balance minors and water.

The alkaline buffering agent may be any such agent capable of providing a 1% product solution with a pH of above 11.5 or even 12. Advantageous alkaline buffering agents are the alkalimetal silicates, as they decrease the corrosion of metal parts in washing machines, and in particular sodium orthometa- or di-silicates, of which sodium metasilicate is preferred. The alkaline buffering . ., 2~g622~

_ agent is suitably present in an amount of from O to 70%
by weight, preferably from O to 30% by weight.

In addition the compositions of the invention can and normally will contain detergency builders in an amount of up to 60% by weight, preferably from 10 to 60 wt% and more preferably up to 40 wt% by weight of the total composition.

Suitable builders include sodium, potassium and ammonium or substituted ammonium pyro- and tri-polyphosphates, -ethylene diamine tetraacetates, -nitrilotriacetates, -etherpolycarboxylates, -citrates, -carbonates, -orthophosphates, -carboxymethyloxysuccinates, etc. Other builders include DPA and ODS. Also less soluble builders may be included, such as for example, an easily dispersible zeolite.
Particularly pre~erred are the polyphosphate builder salts, nitrilotriacetates, citrates, carboxymethyloxysuccinates and mixtures thereo~.

Other conventional materials may be present in minor amounts, provided they exhibit a good dissolving or dispersing behaviour; for example sequestering agents, such as ethylenediamine tetraphosphonic acid;
soil-suspending agents, such as sodiumcarboxymethylcellulose, polyvinylpyrrolidone or the maleic anhydride/ vinylmethylether copolymer, hydrotropes; dyes; perfumes; optical brighteners;
alkali-stable enzymes; germicides; anti-tarnishing agents; lather depressants; fabric softening agents;
oxygen- or chlorine-liberating bleaches, such as dichlorocyanuric acid salts or alkalimetal hypochlorides.

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The remainder of the composition is generally water, - which may be present at least in part as bound water of hydration.

An ideal powdered detergent composition might contain the following (all percentages by weight):

(1) 5-40~ detergent active system;
(2) 0-60% builder;
(3) 0-30% buffer salt;
(4) 0-30% sulphate;
(5) 0-20% bleach system;
(6) 0-4~ enzyme; and (7) minors plus water to 100%.
In another embodiment of the invention, the glycolipid surfactant may be used in a light duty liquid detergent composition such as those taught in US 4 671 894 (Lamb et al), US 4 368 146 (Aronson et al), and US 4 555 366 (Bissett et al), all of which are hereby incorporated by reference into the subject application.

Generally such compositions comprise a mixture of sulphate and sulphonate anionic surfactants together with a suds stabilising agent. These compositions may also comprise nonionic surfactants designed to reduce the level of non-performing ingredients such as solvents and hydrotropes and zwitterionic surfactants for providing enhanced grease and particulate soil removal performance.
Among other ingredients which may also be used in such compositions are opacifiers (e.g. ethylene glycol distearate), thickeners (for example, guar gum), antibacterial agents, antitarnish agents, heavy metal chelators (e.g. ETDA), perfumes and dyes.

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_ The invention is set forth in greater detail in the examples which follow below. These examples are merely to illustrate the invention and are not intended to be limit~ng in any way.

EXAMPLES

10Methodoloov For Pre~aration Of N-Alkvl Lactobionamides Svnthesis of N-A kyl Lactobionamides 15N-alkyl lactobionamides were synthesised by the reaction of commercially available lactobiono-l, 5-lactone with various linear alkylamines either in anhydrous DMF, methanol, or neat as shown below:

HIN(~ 2)~CHl ~ N(C}3,)~C}~
ALlpHA~lc ~ OH

OH OH
[ ACTOBIO~JO~ I~CIONE N ALK~L I~CrO~310~AM~DES

2081~2~

Dimethyl Formamide As Solvent This procedure involved dissolving the lactobiono-l, 5-lactone in minimum amount of anhydrous DMF at 80C
followed by the addition of 1 eq. of alkylamine.
Although this procedure provided excellent yields, the products were colored and repeating washing with solvent was necessary.

Methanol as Solvent This procedure was exercised as described in US 2 752 334 (Walton). Lactobiono-1,5-lactone and the alkylamines were refluxed in methanol and the corresponding colored products were isolated in moderate yields. Continuous washing with solvent was required for decoloration of the products.

Non-solvent Method Excess alkylamines and lactobiono-l, s-lactone were heated at 90-100C with vigorous stirring. The colored Z5 products were isolated in moderate yields.

Examples of each of these methods is set forth in greater detail below.

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~ ~ g'~3 Alternative Synthesis for N-tetradecvl lactobionamide In a 5 L three necked round bottom flask eguipped with a condenser and mechanical stirrer, lactobiono-1,5-lactone (400 g) was dissolved in warm methanol t3.5 L, 50-55C). Melted tetradecylamine (1.0 -eq, 272 g) was then added. The reaction was cooled to room temperature followed by stirring ovexnight to allow complete crystallisation. The desired white product was filtered and reGrystallised from methanol in 91% (550 g) isolated yield. The methanol filtrate contained a mixture of N-tetradecy lactobionamide and tetradecylammonium lactobionate.

The above procedure can also be used to isolate other N-alkyl aldobionamides.

EXAMP~E 1: Pre~axation o~ N-decvl Lactobionamide 20 g of lactobiono-1,5-lactone (1 eq) was dissolved in 40 ml of anhydrous DMF at 75-80C, 8.8 g (1 eq) of decylamine was added. The reaction was maintained at 75-80C with stirring for 30 minutes. The reaction was cooled, ethyl ether (150 ml) was added, the product was filtered and washed with ethyl ether (2 x 100 ml).
Recrystallisation from methanol/ethyl ether gave 80%
yield of the desired product.

2~8~2?.

EXAMPLE 2: Pre~aration of N-dodecvl Lactobionamide -30 g of lactobiono-1,5-lactone (1 eq) was dissolved in 70 ml of anhydrous DMF at 75-80C. 15.85 g (l eq) dodecylamine was added, the reaction mixture was kept stirring at 70-80C for 30 minutes. The reaction was allowed to cool, ethyl ether (200 ml) was added. The product was filtered and washed with ethyl ether (2 x 150 ml) and recrystallisation from MeOH gave 90% of the desired product.

EXAMPLE 3: Pre~aration of N-tetradecyl Lactobionamide Lactobiono-1,5-lactone (20 g, l eq) was dissolved in 60 ml of anhydrous DMF at 65C. 12.5 g of tetradecylamine ~1 eq) was added, the reaction was stirred at 65C for 30 minutes. The reaction mixture was cooled, ethyl ether (2 x 150 ml) was added. The product was filtered and washed with ethyl ether.
Recrystallisation from methanol yielded 92% of the desired product.

EXAMPLE 4: Pre~aration of N-hexadec~l Lactobionamide The same procedure was employed as in Example 3 using lO
g of lactobiono-1,5-lactone (l eq) and 7.1 g of hexadecylamine (l eq). Recrystallisation from MeOH
yielded 90% of the desired product.

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_ EXAMPLE 5: Pre~aration of N-pro~vl Lactobionamide 5 g of lactobiono-1,5-lactone (1 eq) was dissolved in 20 ml of anhydrous DMF at 80C. 0.86 g propylamine (1 eq) was added. The reaction wa~ stirred at 80C for 30 minutes. The solvent was removed. The residue was washed with ethyl ether (2 x 50 ml). Recrystallisation from MeOH/ethyl ether gave 80% yield of the desired product.

EXAMPLE 6: Preparation Qf N-~entyl Lactobionamide Lactobiono-1,5-lactone (5 g, 1 eq) and amylamine (1.41 g, 1 eq) was heated in 30 ml of anhydrous methanol to re~lux for one hour. Small amount o~ activated charcoal was added, flltered when hot. The solvent was removed, the residue was washed with ethyl ether followed by acetone and dried. The yield was 50%.

EXAMPLE 7: Pre~aration of N-octvl Lactobionamide Lactobiono-1,5-lactone (10 g, 1 eq) and octylamine (7.6 g, 2 eq) was heated to 90C for 30 minutes with vigorous stirring. The reaction was allowed to cool, washed with (2 x 150 ml) of ethyl ether.
Recrystallisation twice from MeOH/ethyl ether gave 80 yield of the desired product.

2 0 ~

E~AMPLE_8: Preparation of N-dodecyl Lactobionamide 20 g of lactobiono-1,5-lactone and 11 g of dodecylami~e (1 eq) was dissolved in 200 ml of methanol by heating it to reflux temperature. The reaction mixture was allowed to stir at room temperature overnight. The product was filtered, washed with methanol (100 ml), followed by ethyl ether (2 x 75 ml).
Recrystallisation from MeOH gave 57% yield of the desired product.

EXAMPLE 9: N-lactobionvl dodecvl ~lvcinate 9.0g of dodecyl glycinate hydrochloride was dissolved in 50 ml of anhydrous methanol by gentle heating, 16 ml of 2.0M methanolic ammonia was added, followed by addition of 10.9g (1 eq) of lactobiono-1,5-lactone. The reaction mixture was heated to reflux for 2.Oh and activated charcoal was added and the mixture was filtered hot. The solvent was removed, the product was washed with ethyl ether and dried in a vacuum oven at 40C with P2O5 to give a yield of approximately 75%.

EXAMPLE 10: N-lactobionYl dodecYl beta-alanate The same procedure was employed as described above for the dodecyl glycinate form by reacting 3.0g of dodecyl b-alanate hydrochloride with 3.45 of lacto~iono-1,5-lactone in anhydrous MeOH. The yield was approximately 70%.

2~225 EXAMPLE 11: N-decylox~ro~Yl lactobionamide 50 g of Lactobiono 1,5-lactone is dissolved in 400 ml of methanol (50-55C), oxypropyldecylamine (Adogen(R) 180, 31.6 g, 1 eq) is added. The reaction is cooled to room temperature followed by stirring overnight. The solvent is reduced to 150 ml and acetone (400 ml) is added. The product is filtered, washed with acetone and dried in vacuum oven at 40C.

EXAMPLE 12: Preparation of cocolactobionamide Lactobiono-1,5-lactone (400 g, 1 eq) was dissolved in metha~ol t2.3 litres, 50C) with stirring, and cocoamine (Adogen (Trade Mark) 160-D(R) 211, 8 g, 1 eq) was added slowly over 10 minutes. A~ter the addition was completed, thQ reaction mixtur~ was stirred for a Surther 10 minutes followed by seeding the solution with a small amount of cocolactobionamide, and left overnight with stirring at room temperature. The product was Siltered, washed with warm acetone twice, and dried in a vacuum oven at 40C. The yield was 394 g.

EXAMPLE 13: Pre~aration of tallow lactobionamide Lactobiono-1,5-lactone ~200 g, 1 eq) was dissolved in methanol (1.3 litres, 45C) with stirring, and tallow amine tAdogen (Trade Mark) 170-D(R) 144, 7 g, 1 eq) was added slowly in several portions. ASter the addition was completed, the reaction mixture was stirred overnight at room temperature. The product was filtered, washed with isopropanol Sollowed by acetone, and dried in a vacuum oven at 40C. The yield was 270 g.

. ~ -2~22~

EXAMPLE 14: Pre~aration Oc olevl lactobionamide Lactobiono-1,5-lactone (100 g, 1 eq) was dissolved in methanol (400 ml, 50C), oleyl amine (Adogen (Trade Mark) 127-D, 76.1 g, 1 eq) was added slowly. After the addition was completed, the reaction mixture was stirred overnight at room temperature. The product was filtered, washed twice with acetone, and dried in a vacuum oven at 40C. The yield was 130 g. -EXAMPLE 15:
Preparation of N-dodecvl-N-methvl lactobionamide Lactobiono-1,5-lactone ~8.7 g, 1 eq~ was dissolved in methanol (30 ml, 50C), N-dodecylmethylamine, 5 g, 1 eq) was added. The reaction mixture was stirred overnight at room temperature. The solvent was removed, the product washed with acetone and dried in a vacuum oven at 40C. The yield was 12 g.

SURFACTANCY
In order to determine the effectiveness of these compounds as a surfactant, various physical properties - (ie, CMC, Krafft point, foam height, Zein dissolution, detergency) of the surfactant, which are associated with how "good" a surfactant is, were measured. In particular, these properties were compared to the well known and commonly used ethoxylated nonionic surfactants.
The results of these various measurements are set forth in Examples 16 - 18 below.

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. .

2~22~

_ EXAMPLE 12: Critical Micelle Concentration lCMC) The CMC is defined as the concentration of a surfactant at which it begins to form micelles in solution. Specifically materials that contain both a hydrophobic group and a hydrophilic group (such as surfactants) will tend to distort the structure of the solvent (ie water) they are in and therefore increase the free energy of the system. They therefore concentrate at the surface, where, by orienting so that their hydrophobic groups are directed away from the solvent, the free energy of the solution is minimised. another means of minimising the free energy can be achieved by the aggregation of these surface-active molecules into clusters or micelles with their hydrophobic groups directed toward the interior of the cluster and their hydrophilic groups directed toward the interior of the cluster and their hydrophilic groups directed toward the solvent.
The value of the CMC is determined by surface tension measurements using the Wilhemy plate method.
While not wishing to be bound by theory, it is believed that a low CMC is a measure of surface activity (ie lower ~5 CMC of one surfactant versus another indicates the surfactant with lower CMC is more surface active). In this regard, it is believed that lower CMC signifies that lesser amounts of a surfactant are required to pro~ide the same surfactancy benefits as a surfactant with higher CMC.

The CMC of various surfactants were measured and the results set forth below:

' .

2~8~22~

Surfactant CMC

n-Dodecyl-beta-D-glucoside 1.9 x 10-4 M (25C) n-C12 alcohol (with 7 EO's) 7.3 x 10-5 M (40C) C10-lactobionamide C12-lactobionamide 4.2 x 10-4 M (45C~
C14-lactobionamide 4.5 x 10-5 M (45C) As the table above indicates, the CMC values of N-decyl and tetradecyl lactobionamides were found to be comparable to that of N-Dodecyl-beta-D glucoside and heptaethoxylated dodecyl alcohol. These values indicate that the lactobiona~ide surfactant-~ are comparable to other widely used nonionic surfactants.

EXAMP~E 13: Kra~t Points The temperature at and above which surfactants begin to form micelles instead of precipitates is referred to as Krafft point (Tk) and at this temperature the solubility of a surfactant becomes equal to its CMC.

Rrafft point was measured by preparing a 1%
dispersion of the surfactant in water. If the surfactant was soluble at room temperature, the solution was cooled to oC. When the surfactant did not precipitate out, its Krafft point was considered to be <0C. If it precipitated out, the solution was slowly warmed with stirrin~ in a water bath. The temperature at which the precipitate dissolved was determined to be the Krafft point.

. .

2 ~

If the Krafft point was above room temperature, the solution was first heated rapidly to dissolve all the surfactant. It was then cooled until precipitation occurred, and was then slowly warmed to determine the 5Krafft point described above.

While not wishing to be bound by theory, it is believed that lower Krafft points are indicative of a surfactant being more soluble in aqueous system.
The Xrafft point of various lactobionamides is set forth as follows:
Krafft Point C10 - lactobionamide 0C
lSC12 - lactobionamide 38C
C14 - lactobionamide 46C

This table lndicates that the C10 chain length surfactants would tend to have better surfactancy propert~es than C12 and C14 counterparts at lower temperatures.

EXAMPLE 14: Foam Heiaht Foam is an important attribute in many consumer products (eg consumer products). Foam is one of the dominant factors that determines the commercial value of products such as shampoo, soap, etc. Also, acceptability of many consumer products is closely related to the quality and texture of the foam they produce (psychological aspect).

2036~2a Since most of the foaming data on surfactants is typically obtained by the Ross-Miles method (Ross, J~ and Miles, G.D., Am. Soc. for Testing Material Method D1173-53 Philadelphia, PA. (1953); Oil & Soap (1958) 62:1260) the foaming ability of these surfactants was also acquired using this method.

Tn the Ross-Miles method, 200 mL of a solution of surfactant contained in a pipette of specified dimensions with a 2.9-mm-i.d. orifice is allowed to fall 90 cm onto 50 mL of the same solution contained in a cylindrical vessel maintained at a given temperature (often 60C) by means of a water jacket. The height of the foam produced in the cylindrical vessel is read immediately after all the solution has run out of the pipette (initial foam height) and then again after a given amount of time (generally, 5 min).

Using this method, the ~oam production (measured initially) and foam stability (the height after 10 minutes) are reported. All of the foaming was achieved at 45C in water with 120 ppm hardness. The foam height is represented in millimetres (mm).

The initial foam height and height after 10 minutes (i.e. foam stability) for various surfactants and mixtures of surfactants is set forth below:

Initial HeiahtAfter 10 Minutes C10 lactobionamide 150 5 C12 lactobionamide 160 6 C14 lactobionamide 145 140 Mixture of C12 and C14 155 135 Neodol 91-6 130 5 2~2~ ~

As seen above, the C14 lactobionamide and the mixture of C12 and C14 lactobionamides shows best foam stability.

It should be noted that it is very unusual to get th$s type of foam stability with other nonionics.

Deteraency Evaluation Of N-Dodec~l and N-tetradecvl Lactobionamides General Ex~erimental The detergency of three lactobionamide samples (C12-, C14-and a one to one ratio of C12- and C14-lactobionamides) were evaluated using Tergotometer tests.
The performance of the lactobionamides was compared with that of a commercial ethoxylated nonionic, Neodol (Trade Mark) 25-7 (alkyl chain lengths o~ 12-15 carbons with 7 ethoxy groups). Because it would be expected that N-alkyl lactobionamides would be in a mixed active system, Tergotometer tests were also performed using ratios of linear alXylbenzene sulphonate (LaS~/lactobionamides of 25/75, 50/50, 75/25 and 90/10.
The test cloths used for the majority of tests were Lever clay cloth (a 65/35 polyester/cotton cloth coated with an extremely hydrophobic di-tallow, dimethyl amine cation coated Xaolinitic clay/quartz mixture), the VCD
cloth (a 65/35 polyester/cotton blend, treated with fatty soil collected from vacuum cleaner bags), WXF 30C
(polyester soiled with WFK standard soil) and WFX 30D
(polyester soiled with pigment/sebum) cloths. To test the blood stain removing ability of the _ 33 _ C6171 C12-lactobionamide, the EM~a-116 cloth was used (a cotton cloth stained with milk and with Japanese ink, in addition to blood).

A non-phosphate, zeolite-built burkeite base powder waR dosed over the side at about 1.85 g/l. Hardness was added as a 2:1 ratio of Ca:Mg. The system was kept a pH
= 10 and all tergotometer tests were run for 15 minutes.

Improvement in detergency is measured by change in reflectance values (/~R) between the stained ~loth and the cloth after treatment in the tergotometer, where reflectance values are measured by using a reflectometer and the value is obtained by the difference in reflectance before and after each washing.

EXAMP~E 19 As indicated above, samples of C12, C14 and 1:1 ratio C12 to C14 lactobionamides were evaluated against Lever Clay cloth at tergotometer conditions of 15 C and 180 ppm salt (harsh conditions) in various ratios of anionic (LAS) to the lactobionamide (or commercially available Neodol) and results are set forth below:

/\R at Various Ratios of Anionic to Nonionic I

C12 11.2 10 9.2 10.3 12.2 C14 10.1 9.5 9.6 11.2 15 1:1 C12/C14 11.9 10.7 10.0 12 14 Neodol 25-7 16.8 lS.0 12.8 11.8 12.0 ~' ' , -, 2~622 i _ 34 _ C6171 _ The results above suggest that pure T-~-C (ie 100/0 ratio) under the above conditions gives better detergency performance than each of the three lactobionamide samples (ie 0/100 ratio) and also of any of the samples made up of the various ratios of anionic to nonionics. Also, tested was a LAS/Neodol 25-7 system using the above conditions. Comparing the Neodol results to the lactobionamide results shows that, with respect to the Lever clay cloth, the Neodol 25-7 outperforms the lactobionamides in both the pure and mixed active systems. Both the low temperature and the high hardness used in these tests were suspected of affecting the results.

. EXAMPLE 20 sample5 of C12~ C14 and 1 1 C12 to 14 lactobionamide and commercially available Neodol 25-7 were evaluated against ~CD cloth at tergotometer conditions of 15C and 180 ppm ealt (harsh conditions) in various ratios of anionic (LAS) to lactobionamide or to Neodol (the nonionic) and results are set forth below:

/\R of Various Ratios of Anionic: Nonionic O/lOO25/7s 50/50 75~25 100/0 C12 28.227.5 30 31 32 C14 29.829.5 31.5 33.5 33.8 1:1 C}2/C14 29.8 29.5 29.5 32.5 32.5 Neodol 25-7 25 25.5 31.0 31.5 32 ` . ' . ~
.

2 ~

Although the test results that were obtained using VCD cloths (15C and 180 ppm hardness) did not show as significant a difference between the detergency of the lactobionamide samples and the LAS, the same trend of better results for the anionic surfactant held. But, unlike the results obtained using the Lever Clay cloth (see Example 19 above), the mixed LAS:lactobionamide systems performed at par or better than the LAS:Neodol system even at the harsh conditions of 15C and 180 ppm.

Samples of C12 lactobionamide and Neodol 25-7 (nonionics) were evaluated against VCD cloths at tergoto~eter condition of 40C, 120 ppm hardness and pH
9.7 (mild condition) in various ratios of anionic (LAS) to the nonionics and results set forth below:

~R of Various Ratios o~ Anionic: Nonionic C12 33 34 34.9 36 35 lactobionamide Neodol 25-7 32.8 32 33.0 34 34.5 These results show a R values obtained for various ratios of LAS:Cl2-lactobionamide and LAS:Neodol 25-7 using VCD cloths. The results for these mild conditions (40C, 120 ppm) give results comparable to the same tests run at 15C and 180 ppm, that is the C12-lactobionamide performs at par or a little better than the Neodol 25-7 when tested in mixed nonionic/anionic systems.

~8~

Samples of C12 lactobionamide and Neodol 25-7 (nonionics) were evaluated against E~PA-116 cloth at tergctometer conditions of 40C, 120 ppm hardness and pH
9.7 (mild conditions) in various ratios of anionic (L~S) to the nonionics and results are set forth below~

aR and Various Ratios of Anionic : nonionic 0/10025~75 50/50 75~25 100/0 Neodol 25-7 32.5 34 37 40 41 These results show the a R values obtained for various ratios of LAS:C12-lactobionamide and LAS:Neodol 25-7 on EMPA 116 test cloths (40C, 120 ppm 2:1 Ca:Mg hardness). The results show that while C12-lactobionamide does not remove blood as well as LAS, it does a better job than Neodol 25-7 by about 3 /\R
units.

- Samples of C12 lactobionamide and Neodol 25-7 were evaluated against WKF30C and WFK3OD cloths at tergotometer conditions of 40C, 120 ppm hardness and pH
: 30 of about 10 in various ratios of anionic (LAS) to the nonionics and these results are set forth below:

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.~

2~225 ~ 37 - C~171 a R at Varlous ~atlo~ o~ ~nion~c : Nonlonio 0/lOo 27/75 50~50 75/~5 100/~

C12 15.0 18.0 21.8 25 26 N-odol 25-7 12.~ 16.0 19.5 22.8 26 W~X30C
lo C12 4.0 6.2 9.o ~0.9 ~l.o Neo~ol 25~7 2.0 4.8 ~.0 9.5 11.0 A~ th- re~ult~ indicate, the anionlc ~u~atant ag~ln out~er~orms all ~ur~ an~ mixad anlonic/nonlonto ~y~t-~a. ~galn, the lactobion~ml~e pe~orm~ ~t par or ~lightly better than N-odol 25-7 ln th~ mlxsd actlve an~
the all-nonlonlc ~yst-ma.

~n gen~ral the detergont evnlu~tlon~ ehow that tho sur~act~nts Or th~ lnventlon p~rrorm Ht ~ poor or b~tt~r than the ¢o~monly AvA~lable Neodol 25-7 aga~nst ~lmost all ~ub~trate~ te~ted texc-pt ~ever Clay). Mor-ov-r, ln th~ exam~l~ where partty was not met, cleAnlng WA~ done un~er harsh con~itlona.

. ..

- 2~86?2~) A further assessment of oily soil detergency performance was made by studying the removal of radio-labelled triolein in tergotometer experiments. In this Example reference will be made to the accompanying drawing.

3H triolein was used to assess soil removal:
subsequent to the wash, 4 x 1 ml samples of wash liquor were removed from each pot and the activity determined using a scintillation counter. Percentage detergency was calculated from the relationship:

Aw % Detergency As x 100 wherein Aw is the total activity in the wash liquor and A8 the level o~ activity originally applied to the cloth.

~he wash conditions were as follows: wash ttme 20 minutes, wash temperature 40C, agitation 70 rpm, wash liquor volume 500 ml, product dosage 1 g~l, salt concentration (sodium carbonate) 0.05M, knitted polyester test cloth having a soil level of about 1.9 wt%.

The results of detergency measurements on C14, C12 and coconut lactobionamides alone and in mixtures with C12E03 nonionic surfactant are shown in the accompanying drawing.

., . . ,' ' . ~ :

2~ 2~ --. 7 When th~- laoto~lona~ida~ were mlx~d wlth th~ 3EO
nonionlc, ~yn~rglstic d~terg-ncy WA~ ob~erve~. For t~e C14 matGrial, ~or ~xa~ple, a ~harp ~ynergl~t~c m~ximum (about 65% deter~-ncy) wa~ obs~rvsd at a surfactant compo~ltlon o~ 8~% lacto~lonamide/20~ nonlonic.

~he~e ~t4rg~ncy r~ult~ ~ndicat~ that th~
lacto~ionamide~ may be con~ldered a~ potantlal ~eplac-~ent~ ~or high HLB ~thoxylated nonlonic ~ur~actan~s, especlally ln ~abrlc wa~hlng compo~ition~.

~L

CYclic aldobionamid~ versu~ ll~Q~z~donami In o~der to ~how th~t the aldobi4n~mld-~ (ie having at lc~st two ~cch~r~ d~ unit~ ) o~ th~ i~entlon ar~
advant~g~ou~ rel~tlve to the lin~r 3acch~rlte~ (~g glucon~mide), th~ Xra~t polnt~ of 1 wt% solutlon~ (1 g sur~actant in 99 g wat~r) o~ Clo~ C12 and Cl4 gluconamide~ and laetoblona~lda~ were mea~ur~d.

:, 208~223 - 4~ - C6~71 Glucon~mide~ have th~ gen~ral formula ~O~ o ~OH
~0 whe~ein R and Rl ar~ ae defln~d ~bov~ for th~
aldo~ionamld~s of the lnvention.

$he r~ult~ wer- a~ fOll~W~:
Co~oun~a~ft polnt C10 Gluconaml~ ~40C
~actob~ona~ld-0 C
C12 Glucona~ld~ 95C
Lactoblo~a~ld~ 3~C

C14 Glucona~ide ~100C
~actobionamide 46 C

~hes~ re~ul~s clQarly ehow that the Kraf~t point oS
ths laotoblonam~ae i~ always ~uch lowsr than that o~ th~
glucona~ld~, ie the solubllit~ oS th- lactobionamide i3 much hlg~er.

The lo~er Xrafft polnt lc also a~socia~ed wl~
hlgher ~oa~ing.

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.
.

Claims (12)

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:

1 A detergent composition suitable for cleaning fabrics or hard surfaces, comprising a nonionic glycolipid surfactant which is an aldobionamide.

2 A composition according to claim 1 wherein the aldobionamide has the structure:

wherein A is a sugar moiety which is an aldobionic acid except that it does not contain the OH group normally extending from the carbonyl group on the aldobionic acid;

NR1R2 is attached where the hydroxyl group on the aldobionic acid would normally be found; and R1 and R2 are the same or different and are selected from the group consisting of hydrogen, aliphatic hydrocarbons, aromatic radicals, cycloaliphatic radicals, amino acid esters, ether amines, and mixtures thereof, except that R1 and R2 cannot be hydrogen at the same time.

3 A composition according to claim 2 wherein, on the aldobionamide, R is hydrogen and R1 is an alkyl group having from 8 to 24 carbon atoms.

C6171c2

4 A composition according to claim 2, wherein, on the aldobionamide, A is a disaccharide sugar group forming the compound which is an aldobionic acid except for the OH group.

A composition according to claim 2, wherein the aldobionamide is a lactobionamide having the structure:

wherein R1 and R2 are the same or different and are selected from the group consisting of hydrogen, aliphatic hydrocarbons, aromatic radicals, cycloaliphatic radicals, amino acid esters, ether amines, and mixtures thereof, except that R1 and R2 cannot be hydrogen at the same time.

C6171c2

6 A composition as claimed in claim 2, wherein the aldobionamide is a maltobionamide having the formula:

wherein R1 and R2 are the same or different and are selected from the group consisting of hydrogen, aliphatic hydrocarbons, aromatic radicals, cycloaliphatic radicals, amino acid esters, ether amines, and mixtures thereof, except that R1 and R2 cannot be hydrogen at the same time.

7 A composition as claimed in claim 1, which further comprises a cosurfactant selected from fatty acid soaps, anionic non-soap surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants and zwitterionic surfactants.

8 A composition as claimed in claim 7, wherein the cosurfactant is an ethoxylated alcohol nonionic surfactant.

C6171c2

9 A composition as claimed in claim 1, which is a liquid detergent composition comprising the following (percentages by weight):

(1) 5-70% detergent active comprising the aldobionamide surfactant;
(2) 0-50% builder;
(3) 0-40% electrolyte;
(4) 0.01-5% enzyme;
(5) 0.1-15% enzyme stabiliser;
(6) 0-20% phase regulant;
(7) remainder water and minors.

A composition according to claim 1, which is a powdered detergent composition comprising the following (percentages by weight):

(1) 5-40% detergent active comprising the aldobionamide surfactant;
(2) 0-60% builder;
(3) 0-30% electrolyte (4) 0-30% sulphate;
(5) 0-20% bleach system;
(6) 0-4% enzyme;
(7) minors plus water to 100%

C6171c2

11 A composition according to claim 1, which is a light duty liquid detergent composition comprising the following (percentages by weight):

(a) 0.01-65% anionic surfactant;
(b) 0.1-50% aldobionamide surfactant;
(c) 0-8% suds promoting agent;
(d) 0-10% hydrotrope; and (e) minors plus water to 100%.

12 A composition as claimed in claim 1 and substantially as described herein.