CA2010164C - Immunoconjugats d'anthracycline et methode de production - Google Patents

Immunoconjugats d'anthracycline et methode de production Download PDF

Info

Publication number: CA2010164C
Authority: CA; Canada
Prior art keywords: adm; antibody; anthracycline; immunoconjugate; immunoconjugates
Prior art date: 1988-02-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA002010164A

Other languages

English (en)

Other versions

CA2010164A1 (fr

Inventor

Robert S. Greenfield

Gary R. Braslawsky

Lee J. Olech

Takushi Kaneko

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Co

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-11

Filing date

1990-02-15

Publication date

2000-08-29

1990-02-15 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1991-08-15 Publication of CA2010164A1 publication Critical patent/CA2010164A1/fr

2000-08-29 Application granted granted Critical

2000-08-29 Publication of CA2010164C publication Critical patent/CA2010164C/fr

2010-02-15 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

0 C*=C1CC(*CCC(*=C(CO)[C@](CC2OC*)(Cc(c(O)c3C(c4cccc(OC)c44)=O)c2c(O)c3C4=O)O)=O)*CC1 Chemical compound C*=C1CC(*CCC(*=C(CO)[C@](CC2OC*)(Cc(c(O)c3C(c4cccc(OC)c44)=O)c2c(O)c3C4=O)O)=O)*CC1 0.000 description 4
YIMORSVCLRPREI-UHFFFAOYSA-N O=C(CCCc(cc1)ccc1N(C(C=C1)=O)C1=O)N=O Chemical compound O=C(CCCc(cc1)ccc1N(C(C=C1)=O)C1=O)N=O YIMORSVCLRPREI-UHFFFAOYSA-N 0.000 description 1

CA002010164A 1988-02-11 1990-02-15 Immunoconjugats d'anthracycline et methode de production Expired - Lifetime CA2010164C (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US15518188A	1988-02-11	1988-02-11

Publications (2)

Publication Number	Publication Date
CA2010164A1 CA2010164A1 (fr)	1991-08-15
CA2010164C true CA2010164C (fr)	2000-08-29

Family

ID=22554403

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002010164A Expired - Lifetime CA2010164C (fr)	1988-02-11	1990-02-15	Immunoconjugats d'anthracycline et methode de production

Country Status (2)

Country	Link
CA (1)	CA2010164C (fr)
ZA (1)	ZA89938B (fr)

1989
- 1989-02-07 ZA ZA89938A patent/ZA89938B/xx unknown
1990
- 1990-02-15 CA CA002010164A patent/CA2010164C/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ZA89938B (en)	1989-11-29
CA2010164A1 (fr)	1991-08-15

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EP0328147B1 (fr)	1994-05-11	Immunoconjugués d'anthracyclines à spacer et leurs procédés de préparation
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EP0871490B1 (fr)	2003-03-19	Segments de liaison hydrazone ramifies
US5349066A (en)	1994-09-20	Bifunctional linking compounds, conjugates and methods for their production
CA2016584C (fr)	1999-06-29	Conjugats d'anthracycline ayant un nouvel adapteur et methodes de production
Froesch et al.	1996	Preparation and functional evaluation of new doxorubicin immunoconjugates containing an acid-sensitive linker on small-cell lung cancer cells
Trail et al.	1995	Site‐directed delivery of anthracyclines for treatment of cancer
CA2010164C (fr)	2000-08-29	Immunoconjugats d'anthracycline et methode de production
CA2239183C (fr)	2006-08-29	Segments de liaison hydrazone ramifies

Legal Events

Date	Code	Title	Description
1997-02-14	EEER	Examination request
2010-02-15	MKEX	Expiry