CA2005624A1 - Enzymatic biosensor for the direct measuremnt of at least one biochemical parameter of the skin, process for the preparation of the associated enzymatic membrane, corresponding measurement process and use of the biosensor - Google Patents

Enzymatic biosensor for the direct measuremnt of at least one biochemical parameter of the skin, process for the preparation of the associated enzymatic membrane, corresponding measurement process and use of the biosensor

Info

Publication number
CA2005624A1
CA2005624A1 CA2005624A CA2005624A CA2005624A1 CA 2005624 A1 CA2005624 A1 CA 2005624A1 CA 2005624 A CA2005624 A CA 2005624A CA 2005624 A CA2005624 A CA 2005624A CA 2005624 A1 CA2005624 A1 CA 2005624A1
Authority
CA
Canada
Prior art keywords
biosensor
membrane
enzymatic
substrate
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2005624A
Other languages
French (fr)
Other versions
CA2005624C (en
Inventor
Dominique Bernard
Michel Kermici
Michel Prunieras
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of CA2005624A1 publication Critical patent/CA2005624A1/en
Application granted granted Critical
Publication of CA2005624C publication Critical patent/CA2005624C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

This biosensor comprises a membrane (8) in which is immobilised an enzyme catalysing the transformation of a substrate involved in cutaneous metabolism, means for detecting and measuring a phenomenon caused by this transformation, representing the concentration of the substrate to be determined brought into contact with the membrane (8) and a measuring cell (13) in which a wall region consists of the membrane (8) and which is capable of being shut off, during the measurement, by a region of cutaneous coating (15), the cell (13) being used in combination with means for circulating therein a liquid for dissolving the substrate to be determined. For the measurement, the biosensor is applied onto the skin, buffer is injected into the cell and once the latter is filled the detection and the measurement are performed and then buffer is again circulated to remove the solubilised substrate. This measurement cycle may be repeated without withdrawing the electrode (1). Application to the determination of cutaneous L-lactate using a Clark electrode in combination with an L- lactate oxydase membrane. <IMAGE>
CA002005624A 1988-12-16 1989-12-15 Enzymatic biosensor for the direct measuremnt of at least one biochemical parameter of the skin, process for the preparation of the associated enzymatic membrane, corresponding measurement process and use of the biosensor Expired - Lifetime CA2005624C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816664 1988-12-16
FR8816664A FR2640643B1 (en) 1988-12-16 1988-12-16 ENZYME BIOSENSOR FOR DIRECT MEASUREMENT OF AT LEAST ONE BIOCHEMICAL PARAMETER OF THE SKIN, PROCESS FOR PREPARING THE ENZYMATIC MEMBRANE THEREOF AND MEASURING METHOD THEREFOR

Publications (2)

Publication Number Publication Date
CA2005624A1 true CA2005624A1 (en) 1990-06-16
CA2005624C CA2005624C (en) 1999-12-14

Family

ID=9373057

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002005624A Expired - Lifetime CA2005624C (en) 1988-12-16 1989-12-15 Enzymatic biosensor for the direct measuremnt of at least one biochemical parameter of the skin, process for the preparation of the associated enzymatic membrane, corresponding measurement process and use of the biosensor

Country Status (7)

Country Link
EP (1) EP0384090B1 (en)
JP (1) JP2646271B2 (en)
AT (1) ATE90722T1 (en)
CA (1) CA2005624C (en)
DE (1) DE68907197T2 (en)
ES (1) ES2041028T3 (en)
FR (1) FR2640643B1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667777B1 (en) * 1990-10-16 1995-05-12 Oreal DEVICE FOR THE DOSAGE OF AT LEAST ONE COMPOUND DIRECTLY ON THE SKIN AND CORRESPONDING DOSING METHOD.
AU3183195A (en) * 1994-08-02 1996-03-04 Fsm Technologies Limited Membrane filter unit
WO2017102867A1 (en) * 2015-12-15 2017-06-22 Koninklijke Philips N.V. Surface treatment device and method
JPWO2021100612A1 (en) * 2019-11-19 2021-05-27
FR3103901B1 (en) * 2019-11-28 2023-02-24 Noptrack DETECTION OF A CHEMICAL SPECIES IN THE SWEAT OF A SUBJECT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4020830A (en) * 1975-03-12 1977-05-03 The University Of Utah Selective chemical sensitive FET transducers
US4071020A (en) * 1976-06-03 1978-01-31 Xienta, Inc. Apparatus and methods for performing in-vivo measurements of enzyme activity
US4401122A (en) * 1979-08-02 1983-08-30 Children's Hospital Medical Center Cutaneous methods of measuring body substances
IL82558A (en) * 1986-06-05 1991-11-21 Xienta Inc Apparatus and non-invasive method for measuring blood glucose concentration present at the mucosal surface of a living being

Also Published As

Publication number Publication date
EP0384090A1 (en) 1990-08-29
ATE90722T1 (en) 1993-07-15
CA2005624C (en) 1999-12-14
FR2640643A1 (en) 1990-06-22
ES2041028T3 (en) 1993-11-01
JPH03103224A (en) 1991-04-30
JP2646271B2 (en) 1997-08-27
DE68907197T2 (en) 1994-01-20
DE68907197D1 (en) 1993-07-22
FR2640643B1 (en) 1991-03-29
EP0384090B1 (en) 1993-06-16

Similar Documents

Publication Publication Date Title
JPS5592698A (en) Test strip for glucose determination
Nanjo et al. Enzyme electrode sensing oxygen for uric acid in serum and urine
GB1463133A (en) Test composition device and method for the determination of cholesterol
Palleschi et al. Amperometric tetrathiafulvalene-mediated lactate electrode using lactate oxidase absorbed on carbon foil
AU586150B2 (en) Colorimetric ethanol analysis method and test device
EP0510725A3 (en) Electrochemical cell
GB2337328A (en) Method and apparatus for rapid hygiene testing
Belghith et al. An enzyme electrode for on‐line determination of ethanol and methanol
CA2281769A1 (en) Method for identifying cholesterol in the skin tissue
CA2005624A1 (en) Enzymatic biosensor for the direct measuremnt of at least one biochemical parameter of the skin, process for the preparation of the associated enzymatic membrane, corresponding measurement process and use of the biosensor
AU7578087A (en) Process and agent for the detection of an analyte
Ellis et al. Automated kinetic assays for routine determination of adenosine deaminase and guanase activities of human serum
AU586235B2 (en) Assay for salicylate and apparatus for performing same
JPS56164797A (en) Improved method of determining components in samples
GB1457678A (en) Determination of serum triglycerides and reagents therefor
Scheller et al. Degree of glucose conversion in amperometric glucose oxidase (-mutarotase) membrane electrodes
GB2022249A (en) Determination of ascorbic acid
DK0744466T3 (en) Method for Detecting Lactic Acid in Organic Materials of Nutritional Interest and Biosensor for Performing This Method
GB2230606A (en) Bioelectrochemical reactions in organic solvents
JPS5636048A (en) Enzyme electrode
JPS5758895A (en) Analytical method of creatinine and apparatus
DE68919347D1 (en) MEASURING METHOD OF FRESHNESS AND MEASURING SET THEREFOR.
EP0387697A3 (en) Determination of aminotranferases
FR2418462A1 (en) Enzymic determn. of glucose - by measurement of reaction rate in the presence of competitive inhibitor
Jemmali et al. A polarographic method for the rapid determination of glucose with glucose oxidase

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKEC Expiry (correction)

Effective date: 20121202