CA1336368C - Pad printing device for the transfer of clearly defined quantities of printing medium per surface unit - Google Patents

Pad printing device for the transfer of clearly defined quantities of printing medium per surface unit

Info

Publication number
CA1336368C
CA1336368C CA000572418A CA572418A CA1336368C CA 1336368 C CA1336368 C CA 1336368C CA 000572418 A CA000572418 A CA 000572418A CA 572418 A CA572418 A CA 572418A CA 1336368 C CA1336368 C CA 1336368C
Authority
CA
Canada
Prior art keywords
pad
printing medium
printing
dosage form
pharmaceutical administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000572418A
Other languages
French (fr)
Inventor
Dieter Anhauser
Robert-Peter Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of CA1336368C publication Critical patent/CA1336368C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41FPRINTING MACHINES OR PRESSES
    • B41F7/00Rotary lithographic machines
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41FPRINTING MACHINES OR PRESSES
    • B41F17/00Printing apparatus or machines of special types or for particular purposes, not otherwise provided for
    • B41F17/001Pad printing apparatus or machines

Landscapes

  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Medicinal Preparation (AREA)
  • Printing Methods (AREA)
  • Electrostatic Charge, Transfer And Separation In Electrography (AREA)
  • Manufacturing Of Printed Wiring (AREA)
  • Eye Examination Apparatus (AREA)
  • Handling Of Sheets (AREA)
  • Dot-Matrix Printers And Others (AREA)
  • Coloring (AREA)
  • Decoration By Transfer Pictures (AREA)
  • Materials For Medical Uses (AREA)
  • Press Drives And Press Lines (AREA)
  • Ink Jet (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Inking, Control Or Cleaning Of Printing Machines (AREA)
  • Laminated Bodies (AREA)
  • Control Of Presses (AREA)

Abstract

The invention relates to a pad printing device for the transfer of clea-rly defined quantities of printing medium per surface unit, in which the surface of the pad (20) is enlarged, whilst essentially retaining the same outer shape and shape volume, as well as the use thereof for the at least partial coating of substrates (22) in a predetermined patt-ern, the substrate (22) being a circuit board for producing integrated circuits, a component of a pharmaceutical administration and/or dosage form, a signboard with raised characters, a prepolymer, etc.

Description

,9-DESCRIPTION

The invention relates to a pad printing device for the transfer of clea-rly defined quantities of printing medium per surface unit, as well as the use thereof.

Pad printing processes have been known since 1968 and are also suitablefor printing uneven surfaces to which adapt the flexible printing medium-transferring pad. A pad printer is e.g. described in DE-OS 19 39 437.
The pictorial element to be printed is etched in sunk manner in a block, i.e. the printing form. The printing medium is transferred into said block following a doctor blade process which doses the printing medium received in the block, the pad completely absorbs the printing medium left behind in the block and transfers it to the object to be printed.
A survey of the uses and characteristics of the pad printing process appears in the brochure of Tampoprint GmbH, Daimlerstrasse 27/1, Korntal-Munchingen, to which reference should be made to avoid unnecessary repetition.

Due to their limited space requirements, pad printers are very advan-tageous, because they can be integrated without difficulty in production lines and can also be encapsulated, which is helpful when processing highly active or toxic printing media, such as medicaments, etching inks, polymerization initiators, etc., for the protection of operating personnel and for reducing the evaporation rate of volatile substances.

Hitherto no attempt has been made to use pad printers for the delivery of precisely controlled printing medium quantities. It has surprisingly been found that the known pad printing process permits an accurate dosing of weights per unit area of up to 26 g/m2 in a printing process with a variance of + 2% and below.

As described in the parallel German application filed by the Applicant on the same application date and entitled "Process for the production of an ~r~n~qtration and/or dosage form for medicament active substances ~' ~ 1 336368 by means of a printing process", even highly sensitive ~ c~ nts or control membranes for active substance deliveries can be applied with a constant weight per unit area to corresponding substrates.

The use of the hitherto known means, namelg variation of the pad material (more printing medium is transferred in the case of softer pads) and the viscosity of the printing medium could only lead to the delivery of a slightly increased, but still constant quantity of printlng medium to a substrate. However, this quantity was not sufficient for coating with higher weights per unit area, such as over 100 g/m , so that despite excellent characteristics, the pad printing process was unsuitable for uses such as the production of thicker layers of materials in a predeter-mined pattern and there has also been no interest up to now in applying coatings by using this process. Instead complicated and costly screen-process printing or complicated multistage application processes were used.

The problem of the present invention is to so develop the known device that it is also possible to transfer to a substrate larger printing medium quantities than is possible with conventional pads.

According to the invention this problem is solved by a device of the aforementioned type in that at least the print contact surface of the overall surface of the pad is increased, whilst essentially retaining the same outer shape and shape volume.

The surface enlargement can e.g. comprise screening, roughening, grooving or burling the pad surface and by working a finished pad body, or by producing the enlarged pad surface during moulding of the pad body in a suitable mould. Compared with conventional pads with a smooth surface, the novel pad is suitable for transferring more than three times the hitherto transferable printing medium quantity.

As a result of the inventive development of the known pad printer, it is possible for the first time to use these r~ch~nes or this process ~ ~ 336368 in completely new fields and in advantageous manner for producing coat-ings. It is therefore e.g. usable in the production of signboards witll a thicker paint application, integrated circuits, in which photolacquers or conductor materials can be printed, as well as for the planned appli-cation of polymerization initlators to prepolymers, for applying etching liquids for producing etching patterns, for transferring porcelain paints, for producing pharmaceutical administration and/or dosage forms, such as tablets, as well as dermally applicable systems, which also includes those systems supplying substances through mucous membranes, i.e. rectal and vaginal ~ nl~tration forms. A particularly preferred use is in the production of plaster-like, transdermal therapeutic systems.

The invention makes it possible to unexpectedly increase the printing medium quantity delivered in a printing process and still obtain a con-stant dosing within narrow limits.

The inventive device makes it possible for the first time to produce in a desired form active substance-containing printing media and small active substance doses without any loss of the active substance, such as has been hitherto possible in the surface coating processes, e.g.
for transdermal therapeutic systems, whereby expensive active substance is saved and it is possible to obviate the problem of active substance waste Pli n~tion.

It is now possible in a single production stage through tlle use of suit-able blocks to apply simultaneously and in spatially clearly separated manner several printing media, such as e.g. several dyes, dyes and adhe-sive, adhesive and an aseptic or active substance-containing product in the case of plasters or therapeutic systems and consequently to save one production stage. The block and also the pad can be thermally cont-rolled, in the case of having to process temperature-sensitive materials, or materials only processable in the heated state, such as certain adhe-sives. It is possible in the same way to cool the same and the complete device, if temperature-sensitive materials are to be worked or processed.

~ 1 336368 Through the choice of a suitable pad material it is possible to take account of the different requirements, so that all rubber-elastic mater-ials known to the Expert are suitable, such as natural and synthetic rubber and in particular silicone rubber, which can be selected in accor-dance with the required properties, such as workability, solvent resis-tance, thermal stability or adequate elasticity at low temperatures.

The pad shape can be chosen in accordance with the substrate to be proc-essed. Thus, it is possible to use any conventional shape, such as frustum-shaped, as well as flat or oval pads with an enlarged printing surface.

By means of the inventive device, it is possible in one printing process to transfer a weight per unit area of approximately 200 g/m2 of printing medium and more. A further improvement to the transfer quantity can be achieved by process improvements known to the Expert, such as the use of softer pads, other printing media, etc.

Further features and advantages of the invention can be gathered from the following description relative to the drawings, wherein show:

Fig. 1 a pad printer on applying a printing medium coating to a substrate.

Fig. 2 the pad printer according to fig. 1 on taking up new printing medium from the block.

Fig. 3 an inventive pad with an enlarged surface area.

Fig. 4 a further inventive pad with an enlarged surface area.

Fig. 5 a cross-section through a transdermal, plaster-like, thera-peutic system produced by the inventive device.

Fig. 6 a plan view of a further active substance coating produced wlth the inventive pad printer and having two different active substances.
ig. 7 a further preferred administration form, namely a dragee prod-uced with the inventive device.

Fig. 1 shows the application of a printing medium coating with an inven-tively constructed pad 20 to a flat substrate 22. An elastic, oval silicone rubber pad 20 with a printing medium coating on the enlarged surface area 23 taken in the preceding working stage of the device from the cavity of a block 24 shaped in accordance Witll the desired pattern for the application of the printing medium (cf. fig. 2), which was prin-ted on the flat substrate 22, on which it leaves a uniform printing medium coating thickness following the removal of pad 20. It is possible in the same way to print uneven substrates, e.g. circular substrates or corrugated substrate surfaces, such as utensil shapes, etc.

Fig. 3 shows a preferred development of an inventive oval pad 20, on whose upper area 23 used for printing medium transfer are formed groove-like depressions as a surface enlargement and as a result of which it is possible to absorb and transfer larger printing medium quantities.
The absorbed printing medium quantity in the present process is deter-mined by the etching depth and shape of the pad 24 from which the prin-ting medium is completely removed, after previously being placed in a uniform coating thickness on the block by means of a doctor blade process and in this form is removed and transferred.

Fig. 4 shows another preferred development of the pad 20, which in thiscase is essentially roller-like. On the transfer or application surface of the pad are formed cups for enlarging the surface and which also serve to receive increased printing medium quantities.

Flg. 5 shows an active substance-containing plaster which can be produced by means of the device according to the invention. This can e.g. be produced by the uniform pressing of a ring-like, active substance-~ 336368 impermeable acrylate contact adhesive coating 16 to a cover film 15,which in this case is siliconized paper removed prior to the use of the plaster, as well as a circular control coating 18, which controls through constant thickness and its physicochemical characteristics the substance passage and prlnting on by means of an inventive pad printer an active substance-containing reservoir coating 14 and subsequent lamin-ation with an impermeable backing, in this case an aluminium-polyester ~ n~te 10. Both the control coating 18, whose characteristics are only ensured in the case of high thickness constancy, and the active substance coating 14, whose active substance content is also only ensur-able in the case of high thickness and sur~ace constancy of the applied coating in a form suitable for pharmaceutical uses, can be applied by means of the inventive device.

Fig. 6 shows a plaster as in fig. 5 prior to the application of the backing 10, this plaster having two active substances 14 and 14'. This embodiment can also be produced with a single active substance appli-cation stage using the inventive pad printer, it once again being poss-ible to see the active substance-impermeable contact adhesive ring 16.

Fig. 7 shows another pharmacological administration form which can be produced with the inventive device, namely a sugar-coated dragee 30 with a two-coat core 34,36, which can be produced by printing the coating 36 on a circular substrate 34, without any wastage of the substrate material 34, or the print coating 36.

Further developments, combinations and uses oE the inventive device are readily apparent to the Expert and fall within the protective scope of the present claims.

~ 1 336368 List of Reference Numerals Backing 14 Active substance coating Cover film 16 Adhesive coating 18 Control coating Pad 22 Substrate 23 Enlarged surface 24 Block Tablet 32 Sugar covering 34 Active substance coating 36 Carrier coating

Claims (9)

1. Pad printing device for transferring clearly defined quantities of printing medium per surface unit, characterized in that the area of the printing surface of the pad is enlarged whilst essentially retaining the same external shape and shape volume.
2. Device according to claim 1, characterized in that the surface enlargement comprises screening, roughening, grooving or burling of at least part of the pad surface used for transferring the printing medium.
3. Device according to claim 1 or 2, characterized in that the enlargement of the pad surface takes place by working a finished pad body.
4. Device according to claim 1 or 2, characterized in that the enlarged pad surface part can be produced in a suitable mould during the moulding of the pad body.
5. Use of the device according to claim 1 or 2, for the at least partial coating of substrates in a predetermined pattern, the substrate being a circuit board for producing integrated circuits, a component of a pharmaceutical administration and/or a dosage form, a signboard with raised characters, or a prepolymer.
6. Use according to claim 5, characterized in that the pharmaceutical administration and/or dosage form is a dermally applicable system, such as a transdermal therapeutic system.
7. Use of the device according to claim 3, for the at least partial coating of substrates in a predetermined pattern, the substrate being a circuit board for producing integrated circuits, a component of a pharmaceutical administration and/or a dosage form, a signboard with raised characters, or a prepolymer.
8. Use of the device according to claim 4, for the at least partial coating of substrates in a predetermined pattern, the substrate being a circuit board for producing integrated circuits, a component of a pharmaceutical administration and/or a dosage form, a signboard with raised characters, or a prepolymer.
9. Use according to claim 7 or 8, characterized in that the pharmaceutical administration and/or dosage form is a dermally applicable system, such as a transdermal therapeutic system.
CA000572418A 1987-08-14 1988-07-19 Pad printing device for the transfer of clearly defined quantities of printing medium per surface unit Expired - Fee Related CA1336368C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3727214.4 1987-08-14
DE19873727214 DE3727214A1 (en) 1987-08-14 1987-08-14 TAMPON PRINTING DEVICE FOR TRANSMITTING DEFINED QUANTITIES OF PRINTING MEDIUM PER AREA UNIT

Publications (1)

Publication Number Publication Date
CA1336368C true CA1336368C (en) 1995-07-25

Family

ID=6333819

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000572418A Expired - Fee Related CA1336368C (en) 1987-08-14 1988-07-19 Pad printing device for the transfer of clearly defined quantities of printing medium per surface unit

Country Status (27)

Country Link
EP (1) EP0306636B1 (en)
JP (1) JP2919845B2 (en)
KR (1) KR890701364A (en)
AT (1) ATE71023T1 (en)
AU (1) AU624330B2 (en)
CA (1) CA1336368C (en)
CZ (1) CZ284747B6 (en)
DD (1) DD281987A5 (en)
DE (2) DE3727214A1 (en)
DK (1) DK166201C (en)
ES (1) ES2028948T3 (en)
FI (1) FI88897C (en)
GR (1) GR3003494T3 (en)
HR (1) HRP920833B1 (en)
HU (1) HU204219B (en)
IE (1) IE60688B1 (en)
IL (1) IL87159A (en)
MY (1) MY103535A (en)
NO (1) NO166926C (en)
NZ (1) NZ225243A (en)
PL (1) PL165836B1 (en)
PT (1) PT88137B (en)
SI (1) SI8811566A8 (en)
SK (1) SK280800B6 (en)
WO (1) WO1989001410A1 (en)
YU (1) YU46591B (en)
ZA (1) ZA884678B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19708674C2 (en) * 1996-03-25 2002-02-07 Lohmann Therapie Syst Lts Transdermal therapeutic system with a drug-containing film layer and a soluble release layer, and a method for its preparation
KR100594666B1 (en) * 1999-03-18 2006-07-03 에르테에스 로만 테라피-시스테메 아게 Transdermal therapy system and method for producing the same
DE19955214B4 (en) * 1999-11-17 2006-05-11 Stork Gmbh Method for producing conductor structures
DE10033112C2 (en) * 2000-07-07 2002-11-14 Siemens Ag Process for the production and structuring of organic field-effect transistors (OFET), OFET produced thereafter and its use
DE10256760A1 (en) * 2002-12-05 2004-06-17 Continental Isad Electronic Systems Gmbh & Co. Ohg Insulating varnish applying method for electric machine windings, involves using specific plate or block having recesses/depressions such that varnish remains in depressions until pressed by pressure plug for transfer to conductive element
DE102004045070B4 (en) * 2004-09-15 2006-11-23 Alletto Rothhaar Method for applying an adhesive layer to a workpiece and device for carrying out this method
KR100881232B1 (en) 2007-05-03 2009-02-05 한국기계연구원 Pad Printing Method and Pad Printer
DE102007031971A1 (en) * 2007-07-10 2009-01-15 BSH Bosch und Siemens Hausgeräte GmbH Tampon printing machine has a robotic arm to apply the print and with an integral heating and cooling system for the printed material
DE102019117310A1 (en) 2019-06-27 2020-12-31 Lts Lohmann Therapie-Systeme Ag Process for the production of drug delivery systems using pad printing processes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH25087A (en) * 1901-11-02 1903-03-31 Redard Camille Dr Professeur Removable forceps
US2436761A (en) * 1944-10-24 1948-02-24 Dewey And Almy Chem Comp Textile print blanket
JPS6014585U (en) * 1983-07-07 1985-01-31 シャープ株式会社 Speaker systems for television receivers, etc.

Also Published As

Publication number Publication date
YU46591B (en) 1993-11-16
DE3867391D1 (en) 1992-02-13
IL87159A0 (en) 1988-12-30
PT88137B (en) 1993-09-30
IL87159A (en) 1992-05-25
FI88897B (en) 1993-04-15
AU624330B2 (en) 1992-06-11
NO890185D0 (en) 1989-01-16
FI88897C (en) 1993-07-26
WO1989001410A1 (en) 1989-02-23
ES2028948T3 (en) 1992-07-16
PL165836B1 (en) 1995-02-28
FI891773A (en) 1989-04-13
EP0306636A1 (en) 1989-03-15
HRP920833B1 (en) 1998-10-31
FI891773A0 (en) 1989-04-13
GR3003494T3 (en) 1993-02-17
HRP920833A2 (en) 1994-04-30
EP0306636B1 (en) 1992-01-02
HU883834D0 (en) 1990-02-28
DD281987A5 (en) 1990-08-29
CZ559188A3 (en) 1998-12-16
NO166926C (en) 1991-09-18
NZ225243A (en) 1991-05-28
SI8811566A8 (en) 1995-12-31
PT88137A (en) 1989-06-30
PL273855A1 (en) 1989-03-20
HU204219B (en) 1991-12-30
JP2919845B2 (en) 1999-07-19
YU156688A (en) 1990-04-30
AU1935688A (en) 1989-03-09
SK559188A3 (en) 2000-07-11
MY103535A (en) 1993-07-31
ZA884678B (en) 1989-03-29
NO166926B (en) 1991-06-10
IE60688B1 (en) 1994-08-10
IE882392L (en) 1989-02-14
DK183289A (en) 1989-04-14
NO890185L (en) 1989-02-23
ATE71023T1 (en) 1992-01-15
HUT53576A (en) 1990-11-28
CZ284747B6 (en) 1999-02-17
JPH02500183A (en) 1990-01-25
KR890701364A (en) 1989-12-20
DK183289D0 (en) 1989-04-14
DE3727214A1 (en) 1989-02-23
DK166201C (en) 1993-08-16
DK166201B (en) 1993-03-22
SK280800B6 (en) 2000-07-11

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