CA1230348A - Process for purifying aqueous solution of non- electrolytic organic substance to high purity - Google Patents
Process for purifying aqueous solution of non- electrolytic organic substance to high purityInfo
- Publication number
- CA1230348A CA1230348A CA000474906A CA474906A CA1230348A CA 1230348 A CA1230348 A CA 1230348A CA 000474906 A CA000474906 A CA 000474906A CA 474906 A CA474906 A CA 474906A CA 1230348 A CA1230348 A CA 1230348A
- Authority
- CA
- Canada
- Prior art keywords
- exchange resin
- anion exchange
- basic anion
- aqueous solution
- hydroxyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
ABSTRACT OF THE DISCLOSURE
Process for purifying an aqueous solution of a non-electrolytic organic substance by subjecting the solution first to a cation-removing treatment and thereto an anion removing treatment in a column having a free base type weakly basic anion exchange resin processed in the upper layer portion and a hydroxyl group type strongly basic anion exchange resin in the lower portion.
C-31,708
Process for purifying an aqueous solution of a non-electrolytic organic substance by subjecting the solution first to a cation-removing treatment and thereto an anion removing treatment in a column having a free base type weakly basic anion exchange resin processed in the upper layer portion and a hydroxyl group type strongly basic anion exchange resin in the lower portion.
C-31,708
Description
PROCESS FOR PURIFYING AQUEOUS SOLUTION
OF NON-ELECTROLYTIC ORGANIC SUBSTANCE TO
HIGH PURITY
Back~round of_the Invention The present invention relates to a process for purifying an ag~leous solution of a non-electrolytic organic substance to a high purity.
An aqueous solution of a non-electrolytic organic substance such as glucose, isomerized sugar, malt syrup, sorbitol, xylose, inositol, maltose, cane sugar, honey, glyoxal, glycerin or gelatin contains pigments, salts, organic acids and the like as impurities. Not only adsorbents such as bone black and active carbon but also ion exchange resins are vigorously used for purifying a~ueous solutions of this type. As the conventional ion exchange process widely used for purifying these aqueous solutions, there can be mentioned a process in which an a~ueous solution is first treated in a column packed solely with a hydrogen type strongly acidic cation exchange resin, is then treated in a column packed solely with a free base type weakly basic anion exchange resin and is C-31,70~
~2~
finally treated in a column packed with a mixture of a hydrogen type strongly acidic cation exchange resin and a hydroxyl group type strongly basic anion exchange resin, whereby the aqueous solution is decolori~ed and purified.
However, this resin, whereby the aqueous solution is decolorized and purified. However, this process is defective in that the pH value of the liquid which has been passed through the ion exchan~e resin is reduced with the lapse of time or the liquid is gradually colored by concen-tration under heating. Accordingly, it of-ten happens that the quality of the product is degraded or the productivity is reduced.
It is an object of the present invention to provide a process in which an aqueous solution of a non-electrolytic organic substance is purified to a high purity by using ion exchange resins and a treated product having a high quality is prepared.
Summary of the Invention In accordance with the present invention, there is provided a process for purifying an aqueous solution of non-electrolytic organic substance to a high purity, whcih comprises subjecting an aqueous solution of a non-electrolytic organic substance to a cation-removing treatment with a hydrogen type strongly acidic cation exchange resin, and passing the agueous solution through a column having a free base type weakly basic anion exchange resin packed in the upper layer portion and a hydroxyl group type strongly basic anion exchange resin packed in the lower layer portion, the amolmt of the hydroxyl group type strongly basic anion exchange resin being 5 to 50 percent by volume based on the ~ree base C-31,708 -2 ~3~
type weakly basic anion exchange resin and said hydroxyl group type strongly basic anion exchange resin having a porous resin matrix structure containing a dimethylhydroxy-ethylbenzyl ammonium group as the exchange group.
Brief Description of the Drawi~
Figs. 1 and 2 show graphs of the pH values and electric conductivities of effluen-ts obtained in the examples of the present invention.
Detailed Descr ption of the Invention It has now been found that if an agueous solution of a non-electrolytic organic substance which has been subjected to a cation-removing treatment with a hydrogen type strongly acidic cation exchange resin is passed through a column of a free base type weakly basic anion exchange resin to which a hydroxyl group type strongly basic anion exchange resin having a dimethylhydroxyethyl benzyl ammonium group as an ion exchange group and a porous resin matri~ structure is add~d in the form of a layer in an amount of 5 to 50 percent by volume, a very excellent salt-removing effect can be attained. It is preferred that the free base type weakly basic anion exchange resin and the hydroxyl group strongly basic anion exchange resin be packed in the upper and lower layer portions of the column, respectively, by utilizing the difference of the specific gravity be-tween the two resins. According to the process of the present invention, impurities in the agueous solution of the non-electrolytic organic substance, that cannot easily be removed by the conventional weakly basic anion exchange resins, can be effectively removed by the ion exchange. Therefore, C-31,708 -3-ideal desalting and purification can be accomplished without occurrence of the above-mentioned troubles encountered in the conventional techni~ue.
In the process of the present invention, the hydroxyl group type strongly basic anion exchange resin is added preferably in an amount of 5 to 20 percent by volume based on the free base type weakly basic anion exchange resin.
As the free base type weakly basic anion exchange resin that can be effectively used in the present invention, there can be mentioned, for example, styrene type anion exchange resins such as DOWEX 66 (the trademark of The Dow Chemical Company), Amberlite IRA-93 (the trademark of Rhom & Haas Co., USA) and Dia-Ion WA-30 (the trademark of Mitsubishi Kasei Kogyo Kabushiki KAISHA). As the porous hydroxyl group type strongly basic anion exchange resin having a dimethylhydroxyethylbenzyl ammonium group as the exchange group, there can be mentioned anion exchange resins such as DOWEX MSA-2 and Amberlite IR-910. As the hydrogen type strongly acidic ca-tion exchange resin, there can be mentioned, for example, DOWEX 88 and Amberlite IR-200.
The present invention will now be described in detail with reference to the following exampl~s that by no means limit the scope of the invention.
Example 1 An aqueous solution of beet sugar which had been subjected to a cation-removing treatment with a hydrogen type strongly acidic cation exchange resin is C-31,708 ~4-3~1~
~5-subjected to an anion-removing treatment in a column having 2 ml of DOWEX 66 of the free base type (porous styrene type anion exchange resin manufactured by The Dow Chemical Company) packed in the upper layer portion and 0.2 ml of DOWEX MSA-2 of the hydroxyl type (porous styrene type anion exchange resin manufac-tured by The Dow Chemical Company) according to the process of the present invention, and the obtained results are compared with ~he results of the conventional process.
More specifically, an aqueous solution of beet sugar (BX = 15.1, pH - 2.1, electric conductivity = 2200 ~V), which had been subjected to the cation-removing treatment, is introduced into the resin column at a space velocity of 6, and the pH value and electric conductivity of the effluent are continuously measured to obtain a graph of a solid line shown in Fig. 1. In the drawings, the pH value and electric conductivity are plotted on the ordinate, and the time and flow amount are plotted on the abscissa.
The treatment is carried out under the same conditions as described above by using a resin column in which DOWE~ 66 alone is packed, and the p~ value and elec~ric conductivity of the effluent are measured to obtain a graph of a broken line shown in Fig. 1.
As is apparent from these graphs, according to the process of the present invention, a much higher salt-removing effect than the effect attainable by the conventional process can be attained, and the amount treated of the aqueous solution is increased.
C-31,708 -5-Example 2 The aqueous solution of isomerized sugar (BX =
37.2, pH = 2.0, electric conductivi-ty = 1000 ~V), which had been subjected to a cation-removiny treatment with a hydrogen ~type strongly acidic cation exchange resin, is introduced into a column having the same structure as that of the column used in Example 1, and the ph value and electric conductivity of the effluent are continuously measured to obtain a graph of a solid line shown in Fig. 2.
The treatment of the conventional process is carried out in the same manner as described in Example 1, and the pH value and electric conductivity of the ef~luent are measured to obtain a graph of a broken line shown in Fig. 2.
From these graphs, it will readily be under-stood that accordin~ to the process of the present invention, a much higher salt~removing effect than the effect attainable by the conventional process can be attained and the amount treated of the aqueous solution is increased.
C-31,708 -6-
OF NON-ELECTROLYTIC ORGANIC SUBSTANCE TO
HIGH PURITY
Back~round of_the Invention The present invention relates to a process for purifying an ag~leous solution of a non-electrolytic organic substance to a high purity.
An aqueous solution of a non-electrolytic organic substance such as glucose, isomerized sugar, malt syrup, sorbitol, xylose, inositol, maltose, cane sugar, honey, glyoxal, glycerin or gelatin contains pigments, salts, organic acids and the like as impurities. Not only adsorbents such as bone black and active carbon but also ion exchange resins are vigorously used for purifying a~ueous solutions of this type. As the conventional ion exchange process widely used for purifying these aqueous solutions, there can be mentioned a process in which an a~ueous solution is first treated in a column packed solely with a hydrogen type strongly acidic cation exchange resin, is then treated in a column packed solely with a free base type weakly basic anion exchange resin and is C-31,70~
~2~
finally treated in a column packed with a mixture of a hydrogen type strongly acidic cation exchange resin and a hydroxyl group type strongly basic anion exchange resin, whereby the aqueous solution is decolori~ed and purified.
However, this resin, whereby the aqueous solution is decolorized and purified. However, this process is defective in that the pH value of the liquid which has been passed through the ion exchan~e resin is reduced with the lapse of time or the liquid is gradually colored by concen-tration under heating. Accordingly, it of-ten happens that the quality of the product is degraded or the productivity is reduced.
It is an object of the present invention to provide a process in which an aqueous solution of a non-electrolytic organic substance is purified to a high purity by using ion exchange resins and a treated product having a high quality is prepared.
Summary of the Invention In accordance with the present invention, there is provided a process for purifying an aqueous solution of non-electrolytic organic substance to a high purity, whcih comprises subjecting an aqueous solution of a non-electrolytic organic substance to a cation-removing treatment with a hydrogen type strongly acidic cation exchange resin, and passing the agueous solution through a column having a free base type weakly basic anion exchange resin packed in the upper layer portion and a hydroxyl group type strongly basic anion exchange resin packed in the lower layer portion, the amolmt of the hydroxyl group type strongly basic anion exchange resin being 5 to 50 percent by volume based on the ~ree base C-31,708 -2 ~3~
type weakly basic anion exchange resin and said hydroxyl group type strongly basic anion exchange resin having a porous resin matrix structure containing a dimethylhydroxy-ethylbenzyl ammonium group as the exchange group.
Brief Description of the Drawi~
Figs. 1 and 2 show graphs of the pH values and electric conductivities of effluen-ts obtained in the examples of the present invention.
Detailed Descr ption of the Invention It has now been found that if an agueous solution of a non-electrolytic organic substance which has been subjected to a cation-removing treatment with a hydrogen type strongly acidic cation exchange resin is passed through a column of a free base type weakly basic anion exchange resin to which a hydroxyl group type strongly basic anion exchange resin having a dimethylhydroxyethyl benzyl ammonium group as an ion exchange group and a porous resin matri~ structure is add~d in the form of a layer in an amount of 5 to 50 percent by volume, a very excellent salt-removing effect can be attained. It is preferred that the free base type weakly basic anion exchange resin and the hydroxyl group strongly basic anion exchange resin be packed in the upper and lower layer portions of the column, respectively, by utilizing the difference of the specific gravity be-tween the two resins. According to the process of the present invention, impurities in the agueous solution of the non-electrolytic organic substance, that cannot easily be removed by the conventional weakly basic anion exchange resins, can be effectively removed by the ion exchange. Therefore, C-31,708 -3-ideal desalting and purification can be accomplished without occurrence of the above-mentioned troubles encountered in the conventional techni~ue.
In the process of the present invention, the hydroxyl group type strongly basic anion exchange resin is added preferably in an amount of 5 to 20 percent by volume based on the free base type weakly basic anion exchange resin.
As the free base type weakly basic anion exchange resin that can be effectively used in the present invention, there can be mentioned, for example, styrene type anion exchange resins such as DOWEX 66 (the trademark of The Dow Chemical Company), Amberlite IRA-93 (the trademark of Rhom & Haas Co., USA) and Dia-Ion WA-30 (the trademark of Mitsubishi Kasei Kogyo Kabushiki KAISHA). As the porous hydroxyl group type strongly basic anion exchange resin having a dimethylhydroxyethylbenzyl ammonium group as the exchange group, there can be mentioned anion exchange resins such as DOWEX MSA-2 and Amberlite IR-910. As the hydrogen type strongly acidic ca-tion exchange resin, there can be mentioned, for example, DOWEX 88 and Amberlite IR-200.
The present invention will now be described in detail with reference to the following exampl~s that by no means limit the scope of the invention.
Example 1 An aqueous solution of beet sugar which had been subjected to a cation-removing treatment with a hydrogen type strongly acidic cation exchange resin is C-31,708 ~4-3~1~
~5-subjected to an anion-removing treatment in a column having 2 ml of DOWEX 66 of the free base type (porous styrene type anion exchange resin manufactured by The Dow Chemical Company) packed in the upper layer portion and 0.2 ml of DOWEX MSA-2 of the hydroxyl type (porous styrene type anion exchange resin manufac-tured by The Dow Chemical Company) according to the process of the present invention, and the obtained results are compared with ~he results of the conventional process.
More specifically, an aqueous solution of beet sugar (BX = 15.1, pH - 2.1, electric conductivity = 2200 ~V), which had been subjected to the cation-removing treatment, is introduced into the resin column at a space velocity of 6, and the pH value and electric conductivity of the effluent are continuously measured to obtain a graph of a solid line shown in Fig. 1. In the drawings, the pH value and electric conductivity are plotted on the ordinate, and the time and flow amount are plotted on the abscissa.
The treatment is carried out under the same conditions as described above by using a resin column in which DOWE~ 66 alone is packed, and the p~ value and elec~ric conductivity of the effluent are measured to obtain a graph of a broken line shown in Fig. 1.
As is apparent from these graphs, according to the process of the present invention, a much higher salt-removing effect than the effect attainable by the conventional process can be attained, and the amount treated of the aqueous solution is increased.
C-31,708 -5-Example 2 The aqueous solution of isomerized sugar (BX =
37.2, pH = 2.0, electric conductivi-ty = 1000 ~V), which had been subjected to a cation-removiny treatment with a hydrogen ~type strongly acidic cation exchange resin, is introduced into a column having the same structure as that of the column used in Example 1, and the ph value and electric conductivity of the effluent are continuously measured to obtain a graph of a solid line shown in Fig. 2.
The treatment of the conventional process is carried out in the same manner as described in Example 1, and the pH value and electric conductivity of the ef~luent are measured to obtain a graph of a broken line shown in Fig. 2.
From these graphs, it will readily be under-stood that accordin~ to the process of the present invention, a much higher salt~removing effect than the effect attainable by the conventional process can be attained and the amount treated of the aqueous solution is increased.
C-31,708 -6-
Claims (4)
1. The process for purifying an aqueous solution of a non-electrolytic organic substance to a high purity, which comprises subjecting an aqueous solu-tion of a non-electrolytic organic substance to a cation--removing treatment with a hydrogen type strongly acidic cation exchange resin, and passing the aqueous solution through a column having a free base type weakly basic anion exchange resin packed in the upper layer portion and a hydroxyl group type strongly basic anion exchange resin packed in the lower layer portion, the amount of the hydroxyl group type strongly basic anion exchange resin being 5 to 50 percent by volume based on the free base type weakly basic anion exchange resin and said hydroxyl group type strongly basic anion exchange resin having a porous resin matrix structure containing a dimethylhydroxyethylbenzyl ammonium group as the exchange group.
2. The process according to Claim 1 wherein said weakly basic anion exchange resin is macroporous styrene type resin.
C-31,708
C-31,708
3. The process according to Claim 1 wherein said hydroxyl group type strongly basic anion exchange resin is macroporous styrene type resin.
4. The process according to Claim 1 wherein the amount of said hydroxyl group type strongly basic anion exchange resin is from 5 to 20 percent by volume based on the free base type weakly basic anion exchange resin.
C-31,708 -8-
C-31,708 -8-
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000474906A CA1230348A (en) | 1985-02-22 | 1985-02-22 | Process for purifying aqueous solution of non- electrolytic organic substance to high purity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000474906A CA1230348A (en) | 1985-02-22 | 1985-02-22 | Process for purifying aqueous solution of non- electrolytic organic substance to high purity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1230348A true CA1230348A (en) | 1987-12-15 |
Family
ID=4129881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000474906A Expired CA1230348A (en) | 1985-02-22 | 1985-02-22 | Process for purifying aqueous solution of non- electrolytic organic substance to high purity |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA1230348A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014044753A1 (en) * | 2012-09-20 | 2014-03-27 | Dupont Nutrition Biosciences Aps | Separation and recovery of xylose using weakly basic anion exchange resins |
-
1985
- 1985-02-22 CA CA000474906A patent/CA1230348A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014044753A1 (en) * | 2012-09-20 | 2014-03-27 | Dupont Nutrition Biosciences Aps | Separation and recovery of xylose using weakly basic anion exchange resins |
| CN104661718A (en) * | 2012-09-20 | 2015-05-27 | 杜邦营养生物科学有限公司 | Separation and recovery of xylose using weakly basic anion exchange resins |
| US9777342B2 (en) | 2012-09-20 | 2017-10-03 | Dupont Nutrition Biosciences Aps | Separation and recovery of xylose using weakly basic anion exchange resins |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |