CA1207228A - Teat dip - Google Patents
Teat dipInfo
- Publication number
- CA1207228A CA1207228A CA000439156A CA439156A CA1207228A CA 1207228 A CA1207228 A CA 1207228A CA 000439156 A CA000439156 A CA 000439156A CA 439156 A CA439156 A CA 439156A CA 1207228 A CA1207228 A CA 1207228A
- Authority
- CA
- Canada
- Prior art keywords
- composition
- teat
- film
- cellulose
- former
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
TEAT DIP
Abstract A method and composition for the prevention of mastitis in animals. The composition comprises a water soluble film former such as hydroxpropyl cellulose, ethyl cellulose and methyl cellulose, and chlorhexidine (preferably as the gluconate), carried in a freeze-resistant, rapidly evaporating solvent comprising a volatile alcohol.
When animal teats are dipped into the composition, a liquid film containing chlorhexidine remains on the teats, and the liquid vehicle quickly evaporates to form a protective film that coats the teats to prevent bacterial infection.
Abstract A method and composition for the prevention of mastitis in animals. The composition comprises a water soluble film former such as hydroxpropyl cellulose, ethyl cellulose and methyl cellulose, and chlorhexidine (preferably as the gluconate), carried in a freeze-resistant, rapidly evaporating solvent comprising a volatile alcohol.
When animal teats are dipped into the composition, a liquid film containing chlorhexidine remains on the teats, and the liquid vehicle quickly evaporates to form a protective film that coats the teats to prevent bacterial infection.
Description
~,zr~2z~
., .
Background of the Invention Field of the Invention. This invention relates generally to treatment of animal udders to prevent bacterial infection such as mastitis.
_scri~tion ox the Prior Art The concept of teat treatment to prevent mas~itis by appli-cation of a physical barrier such as a film-forming polymer latex is old in the art as evidenced by the ~ndrews, et al. patent 4,113,854.
The Andrews patent discloses a method for the prevention of mastitis in milk-producing animals in which the teats of the animal are dipped into a solution which is comprised of a film~forming polymer latex and a water soluble polymer thickening agent in an aqueous medium.
In addition, the Andrews patent 4,113,854 in column 1, lines 43 to 63 describes t.he prior film-forming materials containing polyvinyl acetate and polyvinyl chloride or vegetable oils which Andrews found to either be ineffective or to produce irritation to the animal's teat.
~`7Z2~3 Andrews states his solution should have a thioxotropic value of 15 to 1200 dynes/cm2 and a practical upper viscosity limi-t of 10 poise at a shear rate of 250/sec. Anclrews suggests natural or synthetic water soluble polymers which include the modified polymers which are derivatives of cellulose. Andrews points out that cellulose is not water soluble without modification and states that typical cellulose derivatives include methyl, hydroxyethyl and sodium carboxy-methyl cellulose derivatives and combinations thereof. Andrews also requires a polymer latex which has suitable film-forming characteris-tics. The latexes include latexes of styrene butadiene, acrylicpolymers and acrylic copolymers. He states the preferred polymer latexes include ethyl acrylate/methyl methacrylate copolymers, methyl methacrylate/butyl acrylate copolymers and styrene butadiene copoly-mers. An especially preferred material of Andrews is an ethyl acrylate/methyl methacrylate copolymer.
In addition, Andrews suggests adding an antiseptic material such as alcohol, chlorohexidine, iodine, 8-hydxoxy quinoline sulfate or sodium hypocholrite to his mixture.
Andrews contends that when the teat is dipped in the mix-ture, it forms a film around the animal's teat which provides a shieldagainst bacterial infections such as mastitis.
One of the problems with the prior art teat coating is that although the Andrews patent describes such teat coating as water soluble, in practice it has been difficult to completely remove the film barriers on the teat with water which may result in plugging the milk line filters. The sales literature of Andrews' assignee, Minnesota Mining and Manufacturing Company, titled The Physical tarrier Against Mastitis, alludes to -the problem of incomplete-removal by stating "Teat shield will not dissolve in milk. Your filter will trap any entering the milk line."
. .
_3- ~Z~7~
While Andrews emphasizes the physical barrier aspect of a film formed by the combination of polymer latex and a water soluble thickening agent, he also suggests one could incorporate an antiseptic into the material. One of the problems is to provide a workable com-bination of film and antiseptic that do not react with each other.
We have discovered that the combination of chlorohexidine (typically as the gluconate) and a water soluble cellulosic film-former, typically hydroxmethyl cellulose, provides a film that provides long lasting bacterial protection to an animal's teats.
One of the problems associated with prior art teat dips is that during storage the tea dip solution may freeze and separate.
The prasent invention overcomes this problem by use of an alcohol solution which does not freeze under normal barn storage temperatures, e.g~, temperatures down to minus 18C or thereabouts, but below 0C.
The alcohol readily evaporates when placed on the cow's teat to permit the film to rapidly form on the animal's teat.
Still other prior art is described in the Journal of American Veterinary Medical Association article of Farnsworth, Wyman and Hawkinson titled "Use of a Teat Sealer for Prevention of Intra-~0 man~ary Infections in Lactating Cows". This article describes theuse of an acrylic latex film as a physical barrier which is removed by rubbing.
The prior art also shows the use of nonfilm-forming teat dips marketed under the trade name Tesan. The Tesan dip comprises a liquid solution and bactericide of chlorhexidine which is claimed to adhere to the animal's teats.
Another teat dip is described in the product bulletin of Lonza Technical Service Laboratories. Lonza's product uses chlor-hexidine gluconate in combination with other ingredients. The Lonza product is also a nonfilm-forming coating.
Still other publications such as the Journal of Dairy Science lists a number of germicides for use in teat dip preparation.
The present invention comprises an improvement to the prior art teat dips by providing a film-forming liquid that is safe and can be completely removed with water.
z~
Summary of the Invention The prevent invention is directed to the discovery of a teat dip composition containing a cellulosic film former (typically hydroxypropyl cellulose) and an antiseptic such as chlorhexidine typically as the gluconate) in a liquid vehicle including a volatile alcohol. The composition provides a rapidly drying film barrier on animal teats that can easily be removed with water. The composition is resistant to freezing.
Description of the Preferred El~odiment The solution of the present invention is characterized as a liquid at room temperature in which one can immerse an animal teat to provide a liquid coating that adheres to the animal's teat. As the liquid vehicle of the coating evaporates, the coating congeals Jo Eorm a clear film barrier located on the outside of the teat. In order to kill bacteria and prevent mastitis spreading, it is preferred to have an antiseptic material such as chlorhexidine in the film to kill bacteria and prevent bacteria from entering the milk gland in the teat. In the present invention one prepares a solution of a film-forming cellulose derivative such as hydroxpropyl cellulose in a solu-tion comprising a volatile alcohol. To provide added masti~is pro-tection one adds an antiseptic material such as chlorhexidine glu- . `
conate to the solution. The alcohol in the solution provides for rapid evaporation while the hydroxpropyl cellulose worms a physical film barrier around the teat. When it is time to milk the animal, the film on the teat can be thoroughly and completely removed with water.
Examples of the preparation of the solution of the present invention are as follows:
EXAMPLE I
Five parts by weight chlorhexidine gluconate were mixed with 15 parts by weight of hydroxpropyl cellulose and 80 parts by weight 5 ~LZ~72;~3 of isopropyl alcohol at room temperature (70F). The resulting mixture, although liquid, exhibited thixotropy and had characteristics of a light gel solution.
EXAMPLE II
Pive parts by weight of chlorhexidine gluconate were mixed with 40 parts by weight of water. The watex and chlorhexidine glucon-ate were mixed together at room temperature (70F). Next, 15 parts by weight of hydroxpropyl cellulose were mixed with 40 parts by weight of isopropyl alcohol at room temperature. rrhe resulting solutions were then mixed together at room temperature.
An animal teat to be treated was dipped in the light gel solution of the above examples. After removing the teat from the solution there remained a liquid solution of approximately 2-4 mils thickness on the teat. In a few seconds after removal of the teat from the teat dip solution the alconol in the mixture evaporated leav-ing a continuous film over the teat.
The solution, which was applied after milking, produced a film coating that remained in the animal teat for approximately eight hours. The film was then washed off by hosing down the teats with water. The washing action completely removed the film with no ohserv-able residual patches of film on the teat. After repeated testing, no mastitis infection or mastitis spreading was observed in the test animals.
It should be understood the alcohol provides a rapid evapor-ation solvent that allow the liquid film to quickly form into a dur-able coating as the alcohol evaporates. Another benefit of the alco-hol is that it prevents the unused teat dip solution rom freezing in the winter time. Such water as may be in the solution functions to dilute the cellulose material into a light, pourable, gel form as well as acting as a carrier to disperse the antiseptic material throughout the mixture.
~2~7;~
The liquid vehicle in which the antiseptic material and the water soluble cellulose derived film-former is employed preferably includes from about 80% to bout 100~ by weight of volatile alcohol.
The liquid vehicle may include quantities of water ranging from very small amounts up Jo about S0~ by weight of the liquid vehicle. When a teat has been dipped in the teat dip composition, the volatile, low-boiling alcohol constituent evaporates readily, leaving a film on the teat. If significant quantities of water, for example, 50~
by weight of the liquid vehicle, are incoxporated in the liquid vehicle, then the drying of the film appears to proceed in two stages. First, the majority of the volatile alcohol moiety evaporates, leaving a soft, tacky residual film on the teat. A secondary, somewhat more lengthy drying of the coatiny renders the coaxing substantially dry to the touch. If, on the other hand, the vehicle comprises primarily a volatile alcohol such as isopropanol (at least about B0% by weiyht), then, upon evaporation of the alcohol portion ox the liquid vehicle, the coating itself becomes substantially dry to the touch even though it may contain a substantial quantity of water. In one embodiment, in which substantially the entire liquid vehicle is volatile alcohol, evaporation of the vehicle from the coating occurs quickly--within about five minutes--and the resulting coating is dry to the touch and is soft and pliable. It is believed that the film former absorbs some water from the air. Preferably, the liquid vehicle includes a sufficient concentration of volatile alcohol so that when the alcohol moiety evaporates, the film is rendered substantially dry to the touch.
The composition of the invention generally takes the form of a lightly viscous, pourable liquid. It is believed that some light gel formation occurs due to the presence of the cellulosic film former.
Of interest, higher temperatures appear to increase rather than de-crease the viscosity of the composition. Accordingly, when the _7_ ~2~7~Z~
composition is applied to warm teats, the composition tends to solidify on the teats rather quickly. The viscosity of the teat dip can be controlled through judicious selection of the type and quantity of cellulosic film former, and also through the addition of various thickening agents such as fumed silica (e.g., Cab~O-Sil~, a product of Cabot Chemical Company).
Under most milking parlor conditions the preferred range of the film-forming, water soluble cellulosic material, typically hydroxyprop~l cellulose, in the solution varies from a minimum of approximately 10% by weight to a maximum of approximately 20% by weight depending on the thickness of the coating desired. If the concentration of hydroxypropyl cellulose is very low, it produces a thin film coating which may easily break or rupture or even be incom-pletely applied to the animals' teat. On the other hand, if the mixture is too thick, i.e., concentrations of hydroxypropyl cellulose are greater than 20% by weight, it is difficult to apply the mixture to the teat as one cannot obtain a uniform coating over the teat.
Thus, the range of hydroxypropyl cellulose has as its limit the prac-tical range at which it can be applied to the animals' teat which may ~0 vary under various environmental conditions. However, it has been found the preferred amount of hydroxypropyl cellulose for most appli-cations ranges from a minimum of 10% by weight to a maximum of 20%
by weight. Under most milking parlor conditions a solution of approxi-mately 15% by weight produces a film of sufficient durability to last from milking to milking.
The amounts of the bactericide are such that they shoula be effective over at least an eight hour period. While more or less bactericide can be used, the preferred range of chlorhexidine as the bactericide is a maximum of approximately 20% by weight. It should be understood that other bactericides may be used at greater or lesser Cab-O-Sil is a trade mark of Cabot Chemical Company ..~
, :3, ~2~Z~
concentrations; however, it has been found that chlorhexidine glu-conate is ideally suited since it can be retained in the film to provide long lasting antiseptic ac~ion~ If desired, the hydroxpropyl cellulose can be used without the bactericide, but the mastitis pre-vention that is afforded is then limited to the physical barrier Pffects of the film.
While hydroxpropyl cellulose is the preferred material, other cellulosic film formers such as ethyl cellulose or methyl cel-lulose may also be used.
.. . .
., .
Background of the Invention Field of the Invention. This invention relates generally to treatment of animal udders to prevent bacterial infection such as mastitis.
_scri~tion ox the Prior Art The concept of teat treatment to prevent mas~itis by appli-cation of a physical barrier such as a film-forming polymer latex is old in the art as evidenced by the ~ndrews, et al. patent 4,113,854.
The Andrews patent discloses a method for the prevention of mastitis in milk-producing animals in which the teats of the animal are dipped into a solution which is comprised of a film~forming polymer latex and a water soluble polymer thickening agent in an aqueous medium.
In addition, the Andrews patent 4,113,854 in column 1, lines 43 to 63 describes t.he prior film-forming materials containing polyvinyl acetate and polyvinyl chloride or vegetable oils which Andrews found to either be ineffective or to produce irritation to the animal's teat.
~`7Z2~3 Andrews states his solution should have a thioxotropic value of 15 to 1200 dynes/cm2 and a practical upper viscosity limi-t of 10 poise at a shear rate of 250/sec. Anclrews suggests natural or synthetic water soluble polymers which include the modified polymers which are derivatives of cellulose. Andrews points out that cellulose is not water soluble without modification and states that typical cellulose derivatives include methyl, hydroxyethyl and sodium carboxy-methyl cellulose derivatives and combinations thereof. Andrews also requires a polymer latex which has suitable film-forming characteris-tics. The latexes include latexes of styrene butadiene, acrylicpolymers and acrylic copolymers. He states the preferred polymer latexes include ethyl acrylate/methyl methacrylate copolymers, methyl methacrylate/butyl acrylate copolymers and styrene butadiene copoly-mers. An especially preferred material of Andrews is an ethyl acrylate/methyl methacrylate copolymer.
In addition, Andrews suggests adding an antiseptic material such as alcohol, chlorohexidine, iodine, 8-hydxoxy quinoline sulfate or sodium hypocholrite to his mixture.
Andrews contends that when the teat is dipped in the mix-ture, it forms a film around the animal's teat which provides a shieldagainst bacterial infections such as mastitis.
One of the problems with the prior art teat coating is that although the Andrews patent describes such teat coating as water soluble, in practice it has been difficult to completely remove the film barriers on the teat with water which may result in plugging the milk line filters. The sales literature of Andrews' assignee, Minnesota Mining and Manufacturing Company, titled The Physical tarrier Against Mastitis, alludes to -the problem of incomplete-removal by stating "Teat shield will not dissolve in milk. Your filter will trap any entering the milk line."
. .
_3- ~Z~7~
While Andrews emphasizes the physical barrier aspect of a film formed by the combination of polymer latex and a water soluble thickening agent, he also suggests one could incorporate an antiseptic into the material. One of the problems is to provide a workable com-bination of film and antiseptic that do not react with each other.
We have discovered that the combination of chlorohexidine (typically as the gluconate) and a water soluble cellulosic film-former, typically hydroxmethyl cellulose, provides a film that provides long lasting bacterial protection to an animal's teats.
One of the problems associated with prior art teat dips is that during storage the tea dip solution may freeze and separate.
The prasent invention overcomes this problem by use of an alcohol solution which does not freeze under normal barn storage temperatures, e.g~, temperatures down to minus 18C or thereabouts, but below 0C.
The alcohol readily evaporates when placed on the cow's teat to permit the film to rapidly form on the animal's teat.
Still other prior art is described in the Journal of American Veterinary Medical Association article of Farnsworth, Wyman and Hawkinson titled "Use of a Teat Sealer for Prevention of Intra-~0 man~ary Infections in Lactating Cows". This article describes theuse of an acrylic latex film as a physical barrier which is removed by rubbing.
The prior art also shows the use of nonfilm-forming teat dips marketed under the trade name Tesan. The Tesan dip comprises a liquid solution and bactericide of chlorhexidine which is claimed to adhere to the animal's teats.
Another teat dip is described in the product bulletin of Lonza Technical Service Laboratories. Lonza's product uses chlor-hexidine gluconate in combination with other ingredients. The Lonza product is also a nonfilm-forming coating.
Still other publications such as the Journal of Dairy Science lists a number of germicides for use in teat dip preparation.
The present invention comprises an improvement to the prior art teat dips by providing a film-forming liquid that is safe and can be completely removed with water.
z~
Summary of the Invention The prevent invention is directed to the discovery of a teat dip composition containing a cellulosic film former (typically hydroxypropyl cellulose) and an antiseptic such as chlorhexidine typically as the gluconate) in a liquid vehicle including a volatile alcohol. The composition provides a rapidly drying film barrier on animal teats that can easily be removed with water. The composition is resistant to freezing.
Description of the Preferred El~odiment The solution of the present invention is characterized as a liquid at room temperature in which one can immerse an animal teat to provide a liquid coating that adheres to the animal's teat. As the liquid vehicle of the coating evaporates, the coating congeals Jo Eorm a clear film barrier located on the outside of the teat. In order to kill bacteria and prevent mastitis spreading, it is preferred to have an antiseptic material such as chlorhexidine in the film to kill bacteria and prevent bacteria from entering the milk gland in the teat. In the present invention one prepares a solution of a film-forming cellulose derivative such as hydroxpropyl cellulose in a solu-tion comprising a volatile alcohol. To provide added masti~is pro-tection one adds an antiseptic material such as chlorhexidine glu- . `
conate to the solution. The alcohol in the solution provides for rapid evaporation while the hydroxpropyl cellulose worms a physical film barrier around the teat. When it is time to milk the animal, the film on the teat can be thoroughly and completely removed with water.
Examples of the preparation of the solution of the present invention are as follows:
EXAMPLE I
Five parts by weight chlorhexidine gluconate were mixed with 15 parts by weight of hydroxpropyl cellulose and 80 parts by weight 5 ~LZ~72;~3 of isopropyl alcohol at room temperature (70F). The resulting mixture, although liquid, exhibited thixotropy and had characteristics of a light gel solution.
EXAMPLE II
Pive parts by weight of chlorhexidine gluconate were mixed with 40 parts by weight of water. The watex and chlorhexidine glucon-ate were mixed together at room temperature (70F). Next, 15 parts by weight of hydroxpropyl cellulose were mixed with 40 parts by weight of isopropyl alcohol at room temperature. rrhe resulting solutions were then mixed together at room temperature.
An animal teat to be treated was dipped in the light gel solution of the above examples. After removing the teat from the solution there remained a liquid solution of approximately 2-4 mils thickness on the teat. In a few seconds after removal of the teat from the teat dip solution the alconol in the mixture evaporated leav-ing a continuous film over the teat.
The solution, which was applied after milking, produced a film coating that remained in the animal teat for approximately eight hours. The film was then washed off by hosing down the teats with water. The washing action completely removed the film with no ohserv-able residual patches of film on the teat. After repeated testing, no mastitis infection or mastitis spreading was observed in the test animals.
It should be understood the alcohol provides a rapid evapor-ation solvent that allow the liquid film to quickly form into a dur-able coating as the alcohol evaporates. Another benefit of the alco-hol is that it prevents the unused teat dip solution rom freezing in the winter time. Such water as may be in the solution functions to dilute the cellulose material into a light, pourable, gel form as well as acting as a carrier to disperse the antiseptic material throughout the mixture.
~2~7;~
The liquid vehicle in which the antiseptic material and the water soluble cellulose derived film-former is employed preferably includes from about 80% to bout 100~ by weight of volatile alcohol.
The liquid vehicle may include quantities of water ranging from very small amounts up Jo about S0~ by weight of the liquid vehicle. When a teat has been dipped in the teat dip composition, the volatile, low-boiling alcohol constituent evaporates readily, leaving a film on the teat. If significant quantities of water, for example, 50~
by weight of the liquid vehicle, are incoxporated in the liquid vehicle, then the drying of the film appears to proceed in two stages. First, the majority of the volatile alcohol moiety evaporates, leaving a soft, tacky residual film on the teat. A secondary, somewhat more lengthy drying of the coatiny renders the coaxing substantially dry to the touch. If, on the other hand, the vehicle comprises primarily a volatile alcohol such as isopropanol (at least about B0% by weiyht), then, upon evaporation of the alcohol portion ox the liquid vehicle, the coating itself becomes substantially dry to the touch even though it may contain a substantial quantity of water. In one embodiment, in which substantially the entire liquid vehicle is volatile alcohol, evaporation of the vehicle from the coating occurs quickly--within about five minutes--and the resulting coating is dry to the touch and is soft and pliable. It is believed that the film former absorbs some water from the air. Preferably, the liquid vehicle includes a sufficient concentration of volatile alcohol so that when the alcohol moiety evaporates, the film is rendered substantially dry to the touch.
The composition of the invention generally takes the form of a lightly viscous, pourable liquid. It is believed that some light gel formation occurs due to the presence of the cellulosic film former.
Of interest, higher temperatures appear to increase rather than de-crease the viscosity of the composition. Accordingly, when the _7_ ~2~7~Z~
composition is applied to warm teats, the composition tends to solidify on the teats rather quickly. The viscosity of the teat dip can be controlled through judicious selection of the type and quantity of cellulosic film former, and also through the addition of various thickening agents such as fumed silica (e.g., Cab~O-Sil~, a product of Cabot Chemical Company).
Under most milking parlor conditions the preferred range of the film-forming, water soluble cellulosic material, typically hydroxyprop~l cellulose, in the solution varies from a minimum of approximately 10% by weight to a maximum of approximately 20% by weight depending on the thickness of the coating desired. If the concentration of hydroxypropyl cellulose is very low, it produces a thin film coating which may easily break or rupture or even be incom-pletely applied to the animals' teat. On the other hand, if the mixture is too thick, i.e., concentrations of hydroxypropyl cellulose are greater than 20% by weight, it is difficult to apply the mixture to the teat as one cannot obtain a uniform coating over the teat.
Thus, the range of hydroxypropyl cellulose has as its limit the prac-tical range at which it can be applied to the animals' teat which may ~0 vary under various environmental conditions. However, it has been found the preferred amount of hydroxypropyl cellulose for most appli-cations ranges from a minimum of 10% by weight to a maximum of 20%
by weight. Under most milking parlor conditions a solution of approxi-mately 15% by weight produces a film of sufficient durability to last from milking to milking.
The amounts of the bactericide are such that they shoula be effective over at least an eight hour period. While more or less bactericide can be used, the preferred range of chlorhexidine as the bactericide is a maximum of approximately 20% by weight. It should be understood that other bactericides may be used at greater or lesser Cab-O-Sil is a trade mark of Cabot Chemical Company ..~
, :3, ~2~Z~
concentrations; however, it has been found that chlorhexidine glu-conate is ideally suited since it can be retained in the film to provide long lasting antiseptic ac~ion~ If desired, the hydroxpropyl cellulose can be used without the bactericide, but the mastitis pre-vention that is afforded is then limited to the physical barrier Pffects of the film.
While hydroxpropyl cellulose is the preferred material, other cellulosic film formers such as ethyl cellulose or methyl cel-lulose may also be used.
.. . .
Claims (12)
1. A teat dip for the prevention of mastitis in animals comprising an effective quantity of a chlorhexidine antiseptic and a water-soluble film-former derived from cellulose in a liquid vehicle comprising a sufficient quantity of volatile alcohol as to enable rapid evaporation of the liquid and so as to provide the teat dip composition with a freezing point not above about -5°C.
2. The teat dip composition of claim 1 in which the film-former derived from cellulose is present in an amount ranging from about 10 to about 20 percent by weight of the composition.
3. The composition of claim 1 wherein the chlorhexidine antiseptic is chlorhexidine gluconate.
4. The composition of claim 1 wherein the volatile alcohol is isopropanol.
5. The composition of claim 1 wherein the liquid vehicle comprises approximately equal parts of water and volatile alcohol.
6. The composition of claim 1 in which the cellulosic film-former is hydroxypropyl cellulose .
7. A teat dip composition for the prevention of mastitis in animals and comprising an effective quantity of chlorhexidine glu-conate, from about 10 to about 20 parts by weight of a film-former derived from cellulose and selected from the group consisting of hy-droxypropyl cellulose, ethyl cellulose and methyl cellulose, and from about 80 to about 90 parts by weight of a liquid vehicle comprising a volatile alcohol in sufficient quantity to provide the composition with a freezing point of not greater than -5°C.
8. The composition of claim 6 in which the cellulosic film-former is hydroxypropyl cellulose and the volatile alcohol is isopro-panol.
9. A teat dip for the prevention of mastitis in animals comprising an effective quantity of an antiseptic for mastitis, a water-soluble film-former derived from cellulose, and a liquid vehicle comprising a volatile alcohol, said film-former being present in sufficient quantity to form a light gel thickening the composition but rendering it pourable, and said volatile alcohol being present in sufficient quantity such that evaporation of the alcohol moiety form a coating of the teat dip on an animal teat results in a continu-ous, flexible film that is substantially dry to the touch.
10. A teat dip composition for the prevention of mastitis in animals and comprising from about 10 to about 20 parts by weight of a film-former selected from the goup consisting of hydroxypropyl cellulose, ethyl cellulose and methyl cellulose, from about 80 to 90 parts by weight of a liquid vehicle comprising a volatile alcohol in sufficient quantity such that evaporation of the alcohol moiety from a coating of the composition upon a teat results in the formation of a flexible film on the teat that is substantially dry to the touch, and an effective quantity of chlorhexidine gluconate as an antiseptic.
11. The composition of claim 10 in which the volatile alcohol is isopropanol.
12. Method for the prevention of mastitis in an animal comprising dipping the animal's teat into a teat dip composition com-prising an effective quantity of a chlorhexidine antiseptic, a liquid vehicle comprising water and a volatile alcohol, and a water-soluble film-former derived from cellulose in a quantity sufficient to provide a residual, protective, unbroken film on the animal's teat upon re-moval thereof from the teat dip composition, removing the animal's teat from the teat dip composition, and rapidly drying the film remain-ing on the teat to provide a protective, water-soluble, chlorhexidine-containing film thereon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000439156A CA1207228A (en) | 1983-10-17 | 1983-10-17 | Teat dip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000439156A CA1207228A (en) | 1983-10-17 | 1983-10-17 | Teat dip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1207228A true CA1207228A (en) | 1986-07-08 |
Family
ID=4126302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000439156A Expired CA1207228A (en) | 1983-10-17 | 1983-10-17 | Teat dip |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA1207228A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9764059B2 (en) | 2011-01-21 | 2017-09-19 | Avery Dennison Corporation | Chlorhexidine gluconate containing solvent adhesive |
| USD852368S1 (en) | 2017-03-27 | 2019-06-25 | Avery Dennison Corporation | Catheter dressing |
| US10456498B2 (en) | 2013-02-07 | 2019-10-29 | Avery Dennison Corporation | Antimicrobial adhesives having improved properties |
| US11058793B2 (en) | 2011-05-16 | 2021-07-13 | Avery Dennison Corporation | Adhesive containing microparticles |
| US11213432B2 (en) | 2013-03-15 | 2022-01-04 | Avery Dennison Corporation | Transparent cover dressing application system and inclusion of label strip |
| US11337940B2 (en) | 2014-06-05 | 2022-05-24 | Avery Dennison Corporation | Articles with active agent concentrated at the substrate contacting surface and related methods |
-
1983
- 1983-10-17 CA CA000439156A patent/CA1207228A/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9764059B2 (en) | 2011-01-21 | 2017-09-19 | Avery Dennison Corporation | Chlorhexidine gluconate containing solvent adhesive |
| US11058793B2 (en) | 2011-05-16 | 2021-07-13 | Avery Dennison Corporation | Adhesive containing microparticles |
| US11707549B2 (en) | 2011-05-16 | 2023-07-25 | Avery Dennison Corporation | Adhesive containing microparticles |
| US10456498B2 (en) | 2013-02-07 | 2019-10-29 | Avery Dennison Corporation | Antimicrobial adhesives having improved properties |
| US11318223B2 (en) | 2013-02-07 | 2022-05-03 | Avery Dennison Corporation | Antimicrobial adhesives having improved properties |
| US11213432B2 (en) | 2013-03-15 | 2022-01-04 | Avery Dennison Corporation | Transparent cover dressing application system and inclusion of label strip |
| US11337940B2 (en) | 2014-06-05 | 2022-05-24 | Avery Dennison Corporation | Articles with active agent concentrated at the substrate contacting surface and related methods |
| USD852368S1 (en) | 2017-03-27 | 2019-06-25 | Avery Dennison Corporation | Catheter dressing |
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