CA1131499A - Metering apparatus for a fluid infusion system with flow control station - Google Patents
Metering apparatus for a fluid infusion system with flow control stationInfo
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- CA1131499A CA1131499A CA388,045A CA388045A CA1131499A CA 1131499 A CA1131499 A CA 1131499A CA 388045 A CA388045 A CA 388045A CA 1131499 A CA1131499 A CA 1131499A
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Abstract
Case 771124 METERING APPARATUS FOR A FLUID INFUSION SYSTEM
WITH FLOW CONTROL STATION
Thurman S. Jess Nicholas Zissimopoulos Abstract of the Disclosure A system for infusing fluids into the human body includes a peristaltic-type metering apparatus which con-trols the flow of fluid through a disposable administra-tion set. The metering apparatus includes a control system, which allows the volume and rate of flow of the fluid to be infused to be accurately preset by the operator. The control system provides an alarm function in the event of malfunction of the pump or occlusion of the tubing of the administration set, and a minimum pumping rate for maintaining fluid flow through a system after the desired volume of fluid has been infused. Novel power supply circuitry within the control system renders the system immune to power line transients, and novel bubble detector circuit provides for more reliable detection of air bubbles in the tubing. A mechanical linkage between the pressure plate and downline flow restriction lunger of the metering apparatus provides for convenient loading of the administration set and for automatic closure of the plunger prior to use.
WITH FLOW CONTROL STATION
Thurman S. Jess Nicholas Zissimopoulos Abstract of the Disclosure A system for infusing fluids into the human body includes a peristaltic-type metering apparatus which con-trols the flow of fluid through a disposable administra-tion set. The metering apparatus includes a control system, which allows the volume and rate of flow of the fluid to be infused to be accurately preset by the operator. The control system provides an alarm function in the event of malfunction of the pump or occlusion of the tubing of the administration set, and a minimum pumping rate for maintaining fluid flow through a system after the desired volume of fluid has been infused. Novel power supply circuitry within the control system renders the system immune to power line transients, and novel bubble detector circuit provides for more reliable detection of air bubbles in the tubing. A mechanical linkage between the pressure plate and downline flow restriction lunger of the metering apparatus provides for convenient loading of the administration set and for automatic closure of the plunger prior to use.
Description
The present invention relates generally to fluid infusion systems, and more particularly to an improved flow metering apparatus for such systems.
This is a division of copending Canadian Patent Application Serial No. 316,257, filed November 15, 1978.
The infusion of fluids into the human body is usually accomplished by means of an administration set in conjunction with metering apparatus which controls the rate of flow of fluid through the set. Peristaltic-type pumps, which function by repetitively compressing andexpanding a section of tubing, have proven particularly attractive for use in metering apparatus since they do not introduce the possibility of leakage or contamination into the system, while providing positive control of ~luid flow through the system.
one form of peristaltic-type pump which is particularly well adapted for infusion applications is des-` cribed in applicant's issued Canadian Patent 1,088,835 of Thurman S. Jess, issued November 4, 1980. Basically, this pump construction includes individually spring-biased rollers in the pump rotor which provide a uniform compression force, and a spring-biased plunger which restricts the lumen of the administration set downline of the pump rotor to provide a back pressure against which the pump must work. This prevents ' the release of dissolved gas in the tubing section, assists in restoring the tubing to its original shape following co~~
pression by the pump, and prevents uncontrolled gravity flo~
in the event of pump failure.
S In many applications, such as where medication is being administered, it is necessary that the operation of the peristaltic pump be precisely controlled to infuse only a predeternined volume of fluid at a predetermined rate. Thus, the need has developed for a control system for peristaltic-type infusion pumps which enables the operator to preset a quantity and rate of infusion, and which continuously monitors the performance of the pump to insure compliance with the pre-set parameters bv interrupting operation and alerting the operator in the event of a malfunction. Furthermore, it is lS ` desirable that the system be fail-safe, and substantially unaffected in operation or accuracy by power line interruptions or transients. The metering apparatus of the present invention provides these features in an integrated unit which is simple and convenient to use.
Accordingly, it is a general object of the present invention to provide a new and improved system for infusing fluids into the human body.
It is a more specific object of the present inven-tion to provide a new and improved metering apparatus for use in conjunction with an administration set for infusing fluids :
into the human body.
According to the present invention there is provided a fluid metering apparatus for controlling the flow of fluid through the tubing of a fluid aaministration set, the apparatus having a housing with a rotor mounted on the housing for rotation about a fixed axis, the rotor including a plurality of pressure rollers disposed about the circumference thereof. Means is provided, including a pressure plate disposed adjacent the circumference of the rotor so that a segment of the tubing is positioned in compressive engagement with the pr~ssure rollers and fluid is caused to flow through the tubing with rotation of the rotor. Flow restriction means is provided which includes a slidably mounted plunger spring-biased against the tubing for occluding the tubing at a predetermined location downline of the tubing segment to increase the pressure of the fluid in the tubing segment.~ The position of the plunger with respect to the housing varies over a predetermined operating range with the pressure of the fluid in the tubing. There is provided means for rotatably driving the rotor, and occlusion detection means is provided which includes electric switch means operatively engaged with the plunger and responsive to the position thereof in the operating range for interrupting rotation of the rotor upon movement of the plunger to a predetermined position in the operating range corresponding to a predetermined partial occlusion of the tubing by the plunger.
9g BRIEF DESCRIPTION OF THE DRAWINGS
... .. _ The features of the present invention which are believed to be novel are set forth with par-ticularity in the appended claims. The invention, together with the further objects and advantages -thereof, may best be understood by reference to the following description taken in conjunction with the accompanying drawings, in the several figures of which like reference numerals identify like elements, and in which:
Figure 1 is a perspective view of an infusion metering apparatus constructed in accordance with the invention.
Figure 2 is an exploded perspectiv~ view showing the principal components oE the metering apparatus housing.
Figure 2a is a cross-sectional view of the metering apparatus taken along line 2a-2a of Figure 1.
Figure 3 is an enlarged front elevational view of the peristaltic pump utilized in the metering apparatus of Figure 1 broken away to show the rotor and downline occlusion 9~9 stations thereof.
Figures 3a and 3b show the do~nline occlusion station of the pump as seen in Figure 3 in alternate positions.
Figure 4 is a cross-sectional view of the pump ta~:en S along line 4-4 of Figure 3.
Pigures 4a and 4b show the latch member of the do~;n-line occlusion station as shown in Figure 4 in alternate positions.
Figure 5 is an enlarged e~ploded perspective view of the principal components of the fluid metering station of the metering apparatus.
Figure 6 is a simplified functional blocX diagram of the control system incorporated in the metering apparatus of the invention.
lS Figure 7 is a functional block diagram partially in schematic form of the control system.
Figure 8 is a simplified schematic diagram of the bubble detector utilized in the fluid metering apparatus of the invention.
!O Figure 9 is a simplified schematic diagram of the power supplies utilized in the fluid metering apparatus of the invention.
Description of the Preferred Embodiment Referring to the Figures, and particularly to Figure 1, 2 peristaltic-type flow metering system 10 for use in con-~149~
junction with an administration set for controllina the flo~
of fluid into a vein or axtery includes a generally rectangular housing 12 havins a handle 13 at one end thereof for con-venient carrying. The front surface of the housing includes a eontrol panel 14 which allo~s the operator to control anc monitor the operation of the metering a~paratus, and a peri-staltie-type flow metering head 15 for compressing a section of tubing 16 of the administratio~ set to effect control of fluid flow therein. A channel 17 is provided above the metering head 15 for maintaining a portion of the tubing segment in A eonvenient view of the operator whereby flow irregularities ean be more readily observed.
The administration set, of whieh tubing segment 16 is a part, and whieh may be eonventional in design and eon-struetion, is preferably formed of a plastie material such as vinyl and paekaged in a sterile and non-pyrogenie eondition.
To avoid the danger of eontamination, the administration set is normally utilized for one applicatior. only, and is disposed of after use.
The operating mode of the metering apparatus is controlled by means of a push button STOP switeh 20, a push button START switeh 21, and a push button power ON-OFF switeh 22. Eaeh of these push button switches ineludes an internal indieator lamp whieh provides a positive indieation of the ~5 operating mode of the apparatus.
9~3 Various abnormal operating conditions are annunciated by means of in~icator lights 23-27 containec or.
the control panel to the left (as vie~ed in Figure 1) of the mode control push buttons. The operation of these indicator lights ~ill be explained in conjunction ~iit~ the operation of their respective systems within the metering apparatus.
Control panel 14 further includes a digital dis-play 30 of volume infused, a di~ital display 31 of volume to be infused, and a digital display 32 of the fluid flow rate. The volume displayed by display 30 is the volume of fluid actually infused, and can be reset to O by the operator by means of a push button RESET switch 33. Ihe volume to be infused by display 31 is preset by the operator L5 by means of a set of push button switches 34 to indicate a desired volume of fluid to be infused. Similarly, the infusion rate display 32 is preset by the operator by means of a second set of push button switches 35 to indicate the rate at which infusion is to take place.
'O As shown in Figures 2 and 2a, to provide an aes-thetically pleasing front panel surface free of openings which might harbor contaminants, the front panel 14 is preferably constructed from a single seamless panel 36 having necessary transparent sections 37 for viewing readouts 30, 31 and 32.
The push button switches 33-35 associated with these displays 9~
are preferably pressure-sensitive s~-itches, which respond to very s~all deformations of the front panel brought about by finger pressure from the operator to actuate their re-spective circuits. The pressure-sensitive s~-itches are mounted on one side of a printed wiring board 38 behin~
panel 36, with connections fro~ the board e~tending through apertures in the housing to a printed wiring board 28 within the housing. Additional individual system wiring boards 29 are plugged into sockets contained on this board. A plurality of metallic screen panels 39 may be provided between board 38 and housing 12 for the purpose of providing radio fre-quency interference (RFI) shielding for the electronic circuitry of the metering apparatus.
Referring to Figure 3, the peristaltic metering head 15 includes a rotor 40 having four pressure rollers 41 disposed in equi-spaced relation about its circumference.
The rollers are each mounted on a shaft 42 for free rotation thereon, and the shafts are carried on carriages 43 and con-strained to radial movement by respective radial slots 44.
Each carriage 43 is mounted for reciprocation within a radially aligned recess 45 and spring loaded in a radially outward direction by a helical spring 46 disposed within the recess.
The pump also includes a pressure plate S0 having an arcuate working surface 51 which substantially corres-ponds in sha~e to the circumference of the pump rotor a~d is positioned to bring the tuhing segment 16 into co~preC-sive engagement with rollers 41 around at least a porticr of the rotor circumference extending between adjacent rollers. The pressure plate may be reciprocated tohard and away from rotor 40 tc facilitate installation and re-~oval of tubing segment 16 by rotation of an eccentric cam 52, which is constraine~ to operate within a ~ertical slot 53 provided on the pressure plate. Rotation of the cam is accomplishe~ by a shaft 54 and user-actuable lever 55 operatively connected to the cam. When the lever 55 is in its bottom position, as shown in Figure 3, the pressure plate is moved sufficiently close to the rotor circumference to cause tubing seg~ent 16 to be completely occluded by the L5 rollers. Since each of rollers 41 is individually biased into engagement with the tubing segment, the pressure applied by each roller is independent of the number of rollers engaging the tubing segment.
After passing through the peristaltic metering !0 station, tubing segment 16 extends between a light source 60 and a photodetector 61, which together comprise a bubble detector station 62. ~s will be seen presently, it is the function of this statioD to discontinue operation and alert the operator upon formation of a bubble in the tubing segment.
Referring to Figures 3-5, the tubing next passes through a flow restriction station 63. This station in-cludes a pressure block 66 and a slidably ~ounted flo~ re-striction plunger 67 biased asainst the side~all of ~u~ing segment 16. The end of plunger ~7 ~hich engages the tubir.
S segment includes a generally L-shaped hea~ portion 68 having a wedge-shaped working surface 7C and a generally flat control surface 71. Plunger 67 includes a central body portion which is slidably received within a stationary mounting block 73, and which extends through the center of a helical compression spring 74 provided for biasing head 68 into engagement with tubing segment 16.
The working surface 70 o head portion 68 bears against the sidewall of tu~ing segment 16 substantially perpendicular to the direction of fluid flow within the .5 tubing as the tubing is held in posi~ion against pressure block 66, As a result, the lumen of the tubing segment is occluded at the point of engagement, and a downline conduit segment is defined between the point of engagement of the rollers 41 and the point of engagement of the wedge-0 shaped working surface 70. As previously developed, the occlusion of the tubing in this way increases the pressure of the fluid in the tubing segment and prevents separ-` ation of dissolved gases therein.
The control surface 71 of plunger 67 extends substantially parallel to the direction of fluid flow ,, ~ .
. : -3g and is substantially greater an area than the wor~ing surface 70. The relatively large area of the contrcl surface 71 renders the plu~ger more sensitive to pres-sures in t~.e tubing lumen when the p~p is operative so that higher pressures can be exerted by spring 74 to more positively close off the tubinq when the pump is not in operation, without ~etriment to its ability to open at lower operating pressures.
Plunger 67 may be opened to facilitate load-ing or unloading of tubing segment 16 by means of a user-actuated lever 76 mounted for reciprocation with plunger 67. The plunger is constrained to reciprocation along a defined operating path by the stationary mounting block 73 which is mounted to the apparatus housing 14. The helical compression spring bears against this mounting block at one end and against the head of the plunger at its other end, causing the desired bias of the plunger against the tubing segment.
Automatic release cf the plunger is obtained by means of a latch member 77 which is pivotably mounted at 78 to pressure plate 50 and biased by a helical spring 79 for operation within a plane perpendicular to the plunger. The plunger includes a slot 80 in which the latch member 77 is received when the plunger is moved to its `5 full open position, as shown in Figure 3b. The end 81 .
of the plunger may be tapered to facilitate displacement of the latch member prior to seating in slot 80. Once the latch member has been received in the slot, the plunger is locked open and the tubing segment 16 can be readily removed.
To insure that plunger 67 will be released when pressure plate 50 is subsequently closed, mounting block 73 is provided with an actuator pin 82. As shown in Figures 3 and 4, this actuator pin has a tapered end surface 83 which serves to displace the pivotably mounted latch member 77 from slot 80 when the pressure plate is returned to its closed position by rotation of knob 55. In this way, the plunger is automatically released so as to again become spring-biased against the adminis-tration set tubing segment 16 as the metering station is closed. This prevents inadvertent operation of the system without the back pressure and gravity flow pro-tection provided by the plunger. Also, when the pres-sure plate is open, the displacement of latching member 77 prevents the plunger from being latched open. A gate member 84 adjacent the control surface 71 of plunger 67 prevents the tubing segment from being inadvertently pulled free of the compression plunger during operation.
By reason of the tubing segment 16 being held in a highly visible vertical position within channel 17 the flow of fluid therethrough can be readily monitored. Furthermore, this channel obviates the need for additional tubing clamps at the inlet and outlet portions of metering head 15 while at the same time providing an aesthetically pleasing structure on the pump housing.
The above-described metering apparatus including the latching arrangement is also described and is claimed in above-identified Patent Application Serial No. 316,257.
Referring now to Figure 6, the control system for metering apparatus 12 is seen to include a stepper motor 100 which is rotatably coupled to rotor 40 so as to drive the rotor one increment for each step command applied to the motor. To supply the multi-phase signals required for operation of the stepper motor the metering apparatus includes multi-phase motor drive circuits 101 which respond to an applied control pulse to generate a multi-phase output signal which steps~the motor one increment. The control pulses are generated by a variable rate divider 102 which produces an output signal after a predetermined number of input pulses have been received from a continuously running clock 103. The divider, which may be conventional in design and construction, is preset by the user to a desired division rate which is displayed by an associated display device 104. In this way, by setting different division factors into the variable rate diviser 102, the stepper motor can be operated over a wide range of rotational speeds.
To provide a display indicative of the total volume of fluid infused a register 105 responsive to the output pulses fxom divider 102 is provided. The counting state of register 105, and hence the volume : infused,-is displayed by a display device 106. The output pulses from divider 102 are also applied to a register 107 having an associated display device 108. This register is a bi~directional register, which prior to use of the metering apparatus is counted up to a counting state corresponding to the quantity of . fluid to be infused, and then during use is counted down with infusion of the fluid until a zero counting state is reached. At this time the register generates lS an output signal which disables a gate 109 to inter-rupt application of control pulses to motor drive circuits 101.
The control system.of the flow metering ap-paratus 10 is shown in greater detail in Figure 7. ~ere the dlvision factor of variable divider 102, and hence the fluid infusion rate, is seen to depend on ~he counting state of a register 110. This counting state can be con-veniently set by the user by means of the rate setting switches 35 which enable respective NOR gates 112 to supply pulses to the register from a pulse source 113.
1~3~9~
In practice, several NOR gates and rate setting switches are provided to allow each digit of the register to be independently set. The counting state of register 110 is displayed by display device 104 as an indication of S the metering or infusion rate of the apparatus.
The output of register 110 is applied to a co~pari-son circuit 114 wherein the register counting state is com-pared with a predetermined fixed minimu~ rate, typically S ml. per hour, to determine whether the infusion rate es-tablished by divider 102 is greater than or less than the minimum rate. In the event that the desired rate is greater than the minimum rate, comparison circuit 114 produces an out~
put signal which enables NAND gate 115 to provide for establish-ment of a minimum "keep open" rate after the desired quantity of fluid has been infused. To this end, the output of clock 103 is applied to a fixed divider 116 which provides output pulses at a fixed minimum "keep open" rate. These pulses are applied to a NOR gate 117 and, depending on the state of this gate, to an OR gate 118 for application to the motor drive circuits 101. The "keep open" mode is operative only after the desired quantity of fluid has been infused, as signaled by the bi-directional register 107 reaching a zero counting state.
The output signal generated by register 107 upon reaching a zero counting state is applied to the remaining ~3~
input of NAND gate 115 and ~o one input of a NOR gate 119. As a result, NOR gate 119 is inhikited and the application of pulses from variable divider 102 is interrupted. Should N~D
` gate 115 be enabled as a result of the variable rate being S greater than the predetermined minimum flow rate,the zero state output signal from register 107 is applied through an in-verter 120 to a keep open indicator 24 and to an input of NOR gate 117, wherein it serves as an enabling signal. This gate, when enabled, allows the fixed rate pulses from the fixed rate divider 116 to be applied to OR gate 118, and hence to motor drive circuits 101. In this way, a minimum flow rate is maintained even after the desired quantity has been infused.
To provide start-stop control over stepper motor 100 the remaining inputs of NOR gates 117 and 119 are con-lS nected to the output of a start-stop flip-flop 121. This flip-flop may be conditioned to a start state by actuation of the push button START switch 21, or to a stop state by actuation of the push button STOP switch 20, or by occurrence of any one of a number of abnormal conditions, including 'O interruption of power, detection of a bubble in the adminis-tration set, detection of an occlusion in the administration set, or the opening of the metering head pressure plate while the metering apparatus is in operation.
To pxovide an accurate indication of the volume of fluid actually infused, the output of OR gate 118 is ~U3~
applied to a fixed divider stage 122 wherein a constant division factor is applied to generate one output pulse for each milliliter of fluid infused. In practice) where stepper motor 100 is required to step 2,352 times to pump 1 milliliter through tubing segment 16, divider 122 may be set to diviQe by 2,352 to obtain the desired volume-indicative output signal.
This output signal is applied to register 105 wherein it advances the counting state of the register so tha~ the in-stantaneous counting state thereof indicates the volume of fluid actually infused. As previously stated, this volume is displayed by display device 105.
The volume-indicative output pulses from divider 122 are also applied through an OR gate 123 to the stepping input of bi-directional register 107 wherein they cause that L5 register to count down one step toward zero with each milli-liter passing through the system. As stated previously, the counting state of register 107, and hence the volume of fluid to be infused, is displayed by display device 108.
Prior to use of the infusion metering apparatus, ~0 the counting state of regis~er 107 is preset by the user by momentarily applying pulses to the register from pulse source 113. This is accomplished through c NOR gate 124 which is enabled by the operator by actuation of the SET VOLUME switch 34. In practice, one such switch and NOR gate are provided !5 for each decade of the counter. The remaining input of NOR
gate 124 is connected to the output of the start-stop flip-flop 121 to prevent the volume display from being changed while the metering apparatus is in operation.
Register 107 is capable of counting either u~ or down depending on an applied mode control signal. This signal is developed from the output of start-stop flip-flop 121 by means of an inverter 125 so as to oondition register 107 to count up with application of set pul~es from source 113 ~hen the apparatus is stopped, and to count down with application of volume-indicative pulses from divider 122 when the metering apparatus is in operation.
Prior to initial operation of the metering apparatus register 105 is reset by the operator by actuation of push .5 button RESET switch 33. This switch is connected to one in-put of an AND gate 126, the other input of which is connected to the output of the start-stop flip-flop 121 to render the reset switch 33 non-functional while the metering apparatus is in operation. The output of AND gate 126 is applied 0 through an OR gate 127 to the reset inputs of register 106 and divider 122. In this way, the divider and register are simultaneously reset to a zero counting state prior to initial operation of the apparatus.
An auto reset state 130 responsive to initial applica-S tion of power to the apparatus is provided to automatically establish ;
an initial counting state in registers 10r, 107 an~ 110. ~he output of the auto reset stage is applie~ to the remain.ng input of OR gate 127 so as to establish a zero counting state in register 105 and divider 122, and to the reset input Gf register 110 through A~D gate 131. Should the operator atter~pt to set the most significant digit of register 110 above 4, a reset circuit coupled to the remaining input of AND gate 131 also resets the register. In this way the setting of infusion rates in excess of 455 ml. per hour is prevented.
The output of the auto reset stage is also applied to register 107, ~herein it establishes a ~inimum counting state of 1 ml.
to prevent initiation of the "keep open" mode before the metèring apparatus has been placed in operation.
Operation of the infusion metering apparatus is interrupted upon occurrence of an occlusion within the ad-ministration set, as detected by a switch 132 associated with plunger 67 (Figures 3 and 5). This switch, which may be a pressure switch similar to switches 33-35, or a magnet-ically-actuated Hall-effect switch, is actuated by an actuator ~0 lever attached to the plunger when the plunger is allowed to close against the tubing as a result of an occlusion with-in the administration set. The switch provides an output signal which actuates a latch circuit to condition start-stop ~lip-flop 121 to a STOP state and illuminate occlusion indi-'5 cator lamp 25.
,. .
~3~
Operation of the apparatus is also interrupte~.
in the event of a bubble being detected at bubble detector 6~. In this event, an output signal is generated by the bubble detector ~hich actuates a latch circuit to con~itiGr i the start-stop flip-flop 121 to interrupt operation of the metering apparatus. At the same time, B~B~L~ indicator lamp 23 is illuminated to alert the operator.
Operating power for the fluid metering apparatus is supplied by means of two unidirectional current supplies .0 135 and 136 ~thich receive operating power from the AC line through ON-OFF switch 22. A battery 138 is provided as an additional source of operating power in the event of failure of the AC line. The battery is connected through s~itch 22 across the output of power supply 135.
Normally, battery 138 is maintained charged by power supply 135 and the various control circuits of the infusion metering apparatus are powered by this combined : source, while the stepper motor 100 is powered by the power supply 136. To guard against interruption of AC line voltage \
0 the output of the power supply 135 is continuously monitored by a voltage comparator 140. Upon occurrence of a line voltage interruption an output signal is produced by comparator 140 which simultaneously illuminates a BATTERY ON indicator 26 and actuates a relay 141.
; Operation of the metering apparatus is interrupted . -20-,,, . ~ , .
~3~ ;9~
whenever the battery voltage falls below a predetermined minimu~ level for a predetermined period of time. To this end, the battery voltage is continuously monitored by a voltage comparator stage 133. ~pon occurrence of a lo~
voltage condition, an output signal is produced which ac~
tivates a latch circuit to illuminate the B~TTERY LOI~, la~p 27 and initiate operation of a timing ccunter 134. This counter counts the "keep open" output pulses developed by ~ixed divider 116 to obtain a 10 minute time delay. If the low voltage condition persists beyond this delay period an output signal is developed by timing counter 1~4 which causes the 8ATTERY LO~- lamp to flash and conditions start-stop flip-flop 121 to interrupt operation of the metering apparatus.
It should be noted that the operation of comparator 133 is lS entirely independent of comparator 140, and serves as a check on system voltage whether supplied by power supply 135 or battery 138.
Stepper motor 100 is powered by power supply 136 -through transfer contacts on xelay 141. The purpose of these~
~0 contacts is to substitute battery 138 as a source of power for the stepper motor in the event of an AC linè ailure as detected by comparator 140. The various phase windings of motor 100 are individua~lly supplied from power supply 136 by means of switching transistors 142-145 connected in series with the windings.
.~ , . . . .
,.f In accordance with another feature of the apparatus, isolation is obtained between step~er motor 100 ar.~ the pulse-sensitive control circuits of the ~etering apparatus by means of individual optical isolators 146-14q associated with re~
5 spective ones of the switching transistors. Each of the optic~l isolators includes a light detecting ele~;ent connected between the motor current source and a respective one of the switching transistors, and a light e~!itting diode (LED) element connected to the output of a respective one of inverting am-10 plifiers 150-153. These amplifiers receive phase control signals fro~. motor drive circuits 101 through respective NOR gates 154-157 which serve as a safety shutoff control means for the metering apparatus.
The NOR gates 154-157 are disabled when the start-15 stop flip-flop 121 is conditioned to a stop mode by means of an OR gate 158 having an output connected to one input of each of the I~OR gates. Also, these NOR gates can be dis-abled by outputs from bubble detector 62 and occlusion switch 132 through an additional OR gate 159 ~hich provides an 20 ~dditional input to OR gate 158. Thus, occurrence of an occlusion, detection of a bubble, or conditioning of the start-stop flip-flop to a stop state for any reason causes the interruption of control signals to optical isolators 146-149 and interruption of drive power to stepper motor 100.
~S In operation, the user initially sets an infusion ~33L~9~
rate by actuating switch 35 t~ apply a requisite n~m~er of pulses to re~ister 110. The counting state of this register sets the variakle divider 102 such that control pulses are developed at the output thereof with a repetition rate com-mensurate with the desired infusion rate. These control pulses are applied through NOR gate 119 to the motor drive circuits 101 wherein they are utilized to generate multi~le phase control signals suitable for controlling the operation of the multi-phase stepper motor 100. Each of the phase signals developed by drive circuits 101 is applied through a respective one of NOR gates 154-157 and inverter amplifiers 150-153 to a respective one of optical isolators 146-149.
These isolators in turn control conduction in respective ones of drive transistors 142-145 to apply current from p~wer supply 136 ~o stepper motor 100. In this way, the stepper motor turns the peristaltic rotor 40 at a rate es-tablished by the operator.
To provide a continuous readout of fluid vo~ume infused the dri~e pulses applied to the drive circuits 101 are also applied to divider 122 to develop pulses indicative of the number of complete milliliters infused. These pulses are counted by register 105 to provide a display in device 106 indicative of the actual quantity of fluid infusPd.
Prior to initial operation of the apparatus an initial counting state is established in register 107 by . ~ .
9~
momentary application of pulses from pulse source 113 through NOR gate 124 and OR gate 123 to esta~lish an initial counting state indicative of the total volume of fluid to be infused.
Register 108 is conditioned to count up at this time by i start-stop flip-flop 121 through inverter 125.
Once this volume is set, operation is started by actuation of switch 21 and register 107 is conditioned to count down by flip-flop 121. Pulses from divider 122 indi-cative of actual volume infused are now applied through C~
0 gate 123 to count register 107 down toward zero. When the register reaches a zero countin~ state, indicating that the desired volume of fluid has been infused, an output signal from register 107 inhibits NOR gate 119 and prevents further operation of stepping motor 100 by pulses from the variable ; divider 10~. However, should the rate established by vari-abJ.e divider 102 be greater than a predetermined minimum infusion rate, comparison circuit 114 provides an enabling signal to NAND gate li5 which allows the output signal from register 107 to enable NOR gate 117 through inverter 120.
This establishes a "keep open" mode of operation wherein pulses from fixed divider 116 provide motor drive circuits 101 with stepping command signals at a frequency which maintains a desired minimum flow rate through the system.
Registers 106, 107 and 110 are automatically reset upon initial operation of the system by the auto reset cir-,:.
. .
~3~99 cuit 130. Register 105 may also be manually reset by stitch 33 when the start~stop flip-flop 121 is conditione~
to a stop state.
Protection against occlusion in the administrat~on set is provided by s~Titch 132, which conditions flip-flGp 121 to a stop state and inhibits AND gates 154-157. ~imilarl~, protection against the formation of bubbles within the ad-ministration set is provided by bubble detector 62, which also conditions flip-flop 121 to a stop state and inhibits AND gates 154-157. Protection against AC line failure is provided by voltase comparator 140 ~7hich actuates relay 141 to switch stepper motor 100 to battery 138, and by voltage comparator 133 which interrupts operation of the apparatus upon occurrence of a low voltage condition for a predetermined period of time.
Upon occurrence of any one of the above alarm functions, or upon infusion of the desired fluid volume, an aural alarm 160 is actuàted to alert the operator that attention to the apparatus is required. A s~itch associated with the pressure plate of the pump head locks out the alarm when the pump head is opened.
Referring to Figure 8, the bubble detector 62 of the infusion apparatus includes an AC-powered detection circuit which offers improved detection sensitivity and stability.
Basically, the detection circuit, as shown in Figure 8, comprises a multi-vibrator 161 consisting of three NA'~D
gates 162, 163 and 164. A capacitor 165 connected to the output of gate 163 and a potentiometer 166 connected to the output of gate 164 provide an RC time constant which determine the fre~uency of the multi-vibrator output signal in a manner well ~no~n to the art. A diode 167 is connected between the arm of potentiometer 166 and the output of gate 164 to vary the duty cycle of the oscillator output signal.
A fixed impedance 168 connected in series ~7ith the body of potentiometer 166 provides a desired adjustment range.
The AC signal generated by multi-vibrator 161 is applied through an impedance 169 to the base of a transistor 170. The emitter of transistor 170 is connected to ground and the collector is connected to the cathode of a light emitting diode ~LED) which comprises the light source 60 disposed on one side of the administration set tubing seg-ment 16. The anode of the LED is connected to a source of positive unidirectional current through a resistor 171. As a result, the AC signal developed by multi-vibrator 161 is amplified by transistor 170 and utilized to drive the LED, causing the LED to produce a light output which varies at a rate dependent on the output fre~uency of the multi-vibrator.
The altèrnating light developed by the LED is detected by photodetector 17~ and associated amplifier transistor 173, which together comprise the light detector :
~3~9~
61 adjacent tubing segment 16. The collectors of photo-detector 172 and transistor 173 are connected to the positive unidirectional current source of the apparatus, an~ the emitter of detector 172 is connected to the base of transistor 173. The emitter of transistor 173 is connected to ground throu~h a resistor 174 and through respective diodes 175-177 to respective inputs of a dual Schmitt trigger 178. The cathodes of diodes 175-177 are connected to ground by respective ones of capacitors 180-182 and re-sistors 183-185 in parallel circuit configuration. These elements serve in conjunction with the 2iodes a signal de-tector, ger.erating a DC signal at the inputs of trigger 178 dependent on the amplitude o the AC signal produced by de-tector 61. Trigger 178, which may be a commercially avail-able component such as a type MC14583B marketed by Motorola, produces an output upon reduction belo~ a predetermined threshold level of the DC signal developed at either of the inputs associated with diodes 176 and 177. The input associated with diode 175 functions as an enabling input for both triggers. The output of Schmitt trigger 178 is applied to one input of an OR gate 179.
The emitter of transistor 173 is also connected to ground through series-connected resistors 186 and 187.
The signal developed at the junction of the two resistors ~5 is filtered by a series connected resistor 188 and a , cap~citor 189 and parallel connected resistor connected to ground and applied to the remairing input of OR gate 179.
In this way OR gate 179 is provided with the output signal developed by the two Schmitt triggers 178 and a DC control sisnal developed across capacitor 189, either of which can result in a bubble-indicative output from the gate in ~he ~event of a bubkle occurring in tubing segment 16. The out-put of Schmitt triggers 178 and the output of OR gate 179 are also connected to the positive unidirectional current source of the system by respective resistors.
Since the output of OR gate 179 is dependent on both the amplitude of the AC signal as rectified and applied to the parallel-connected Schmitt triggers 178, and on the DC signal developed across capacitor 189, the bubble de-LS tector utilized in the metering apparatus provides two in-dependent control channels. The first channel, which utilizes Schmitt triggers 178, astablishes a hignly precise threshold below which an alarm output is produced. The second channel, which depends only on the input characteristic of !0 gate 179 and is less precise, serves as a backup in the event of failure of the Schmitt triggexs in an active mode.
In order for bubble detector 62 to not provide an output, it is necessary that the DC signals applied to the Schmitt triggers as a result of rectification by diodes 176 and 177 be above a predetermined minimum level, which -28~
, ., , ;
1~3~9~
is possi~le only when there is flui~ ~,ithin tubing segment 16 which acts as a lens to direct light from light source 60 to detector 172. In the event o~ failure of the light source or the detector, or any other component of the syste~, the DC signal applie~ to the Schmitt triggers is removed ard an alarm output is generated. In the event of failure of the Sc~itt triggers, an alarm output will be developed ~y OR gate 179 upon loss of the DC signal from capacitor 189.
Th~ use of an AC signal eliminates drift in the circuitry as a factor affecting the threshold level of the Schmitt triggers, thereby allowing the threshold to be set closer to the normal operating level of the system for greater detection efficiency.
Transient spikes on the AC line, which are parti-cularly prevalent in institutions such as hospitals ~here lS electrical machinery is in operation, introduce the potential of spurious counts in the digital registers and gates utilized in the control circuits of the metering apparatus.
For this reason, it is imperative that the greatest possible isolation be provided by power supplies 135 and 136 between the control circuits and the AC line, particularly in view of the possibly critical life-determining nature of the metering apparatus.
To this end, separate power supplies each incor-porating special transient protection features are provided ~5 in the metering apparatus. Referring to Fiyure 9, it is ~L~31a~
seen that the two po~er supplies 135 and 136 share a co~mor.
power transformer 190 which includes individual secondary indings 191 and 192 each electrostatically shielded from the line. The output of secondary winding 191 is connected across a bridge rectifier lq3 within power supply 136. The positive polarity output of bridge rectifier 193 is connected to the positive polarity input terminal 194 of a first four-texminal filter capacitor 195. The negative input terminal 196 of this capacitor is connected to the negative polarity output of the bridge rectifier.
Filter capacitor 195 is an electrolytic type capacitor which includes four terminals; a first pair of terminals associated with respective ends of the positive plate of the capacitor, and a second pair of terminals lS associated with respective ends of the negative or foil side of the capacitor.
The output terminals 197 and 198 of capacitor 195 are connected to a conventional voltage regulator circuit which includes a series-connected regulator transistor 200.
In a manner well known to the art, the conduction state of transistor 200 is varied in response to the voltage level existing at the output of power supply 136 so as to maintain the voltage level constant. To this end, a zener diode 201 ànd resistor 202 are connected across the output electrodes of the capacitor to develop a reference voltage. This ~3~
reference voltage is compared within a comparator amplifier 203 ~ith a portion of the output voltage of the po~er supply as developed by a potentiometer 204 connected acrccs the output terminals of the supply. The output of compara-tor 203, representing the deviation of the output volta~e from a reference level, is applied to a transistor 205 ~hich serves to amplify the erxor signal prior tc applica-tion to the base of transistor 200. Additional regulation to compensate for changes in current load is provided by a series-connected resistor 206 at the emitter of transistor 200. This register develops an additional error signal ~hich is applied through three series-connected voltage dropping diodes 207 to the base of the error amplifier transistor 205. Protection against transient spikes is provided by reverse-biased diodes 208 and 209 connected across the input and output leads of the voltage regulator, respectively.
Power supply 135, which is virtually identical to power supply 136, includes a bridge rectifier 210 con-nected across secondary winding 192, and a four terminal ~ilter capacitor 211 having input terminals 212 and 213 connected across the output of the bridge rectifier. The output terminals 214 and 215 of the capacitor are connected to a series regulator circuit similar to that contained in power supply 136, including a series regulator transistor , ~3~
216, a voltage refe~ence zener diode 217 an~ a diffexential amplifier 218 with similar functions. ~ filter capacitor 220 is connected across the output of the power supply to provide additional filterin~.
~he described power supply arrangement has the a~-vantage of providing a high degree of filtering between the AC line and the respective power supply busses of the meter-ing apparatus. The four-terminal filter capacitors are particularly effective in this respect, in that any transient currents attempting to enter or leave the respective power supplies must pass through the electrodes of the capacitor, since these electrodes are relie~ upon to complete the metallic circuit. As a result, the filtering action of the capacitors is not reduced with transients of higher frequencies, as ~ n conventional filter capacitors.
The use of separate power supplies, each utilizing the four-terminal filter capacitor component, provides a very high degree of isolation between the stepper motor circuit and the digital control circuitry of the metering apparatus.
This is desirable because of the relatively high switching transients inherent in the operation of a stepper motor, and the possibility of these transients affecting the critical digital control circuitry.
Thus, the invention provides a flow metering appar-atus for fluid infusion systems which allows ~he operator to ~3~9~
directly select fluid flow rate and volume ~ithout the nee~
- for calculations.- The apparatus is convenient to install and does not require particular skills on the part of the operator for its operation. Protection is provided wit~n the apparatus against malfunctions in the administratior set and with the apparatus itself, in the event of which the operator is signaled and operation of the apparatus is terminated. The apparatus is portable and of a construction which lends itself to convenient use in a hospital environ-ment.
While a particular emkodiment of the invention has been shown and described, it will be obvious to those skilled in the art that changes and modifications may be made therein without departing from the invention in its broader aspects, and, therefore, the aim in the appended claims is to cover all such changes and modifications as fall within the true spirit and scope of the invention.
This is a division of copending Canadian Patent Application Serial No. 316,257, filed November 15, 1978.
The infusion of fluids into the human body is usually accomplished by means of an administration set in conjunction with metering apparatus which controls the rate of flow of fluid through the set. Peristaltic-type pumps, which function by repetitively compressing andexpanding a section of tubing, have proven particularly attractive for use in metering apparatus since they do not introduce the possibility of leakage or contamination into the system, while providing positive control of ~luid flow through the system.
one form of peristaltic-type pump which is particularly well adapted for infusion applications is des-` cribed in applicant's issued Canadian Patent 1,088,835 of Thurman S. Jess, issued November 4, 1980. Basically, this pump construction includes individually spring-biased rollers in the pump rotor which provide a uniform compression force, and a spring-biased plunger which restricts the lumen of the administration set downline of the pump rotor to provide a back pressure against which the pump must work. This prevents ' the release of dissolved gas in the tubing section, assists in restoring the tubing to its original shape following co~~
pression by the pump, and prevents uncontrolled gravity flo~
in the event of pump failure.
S In many applications, such as where medication is being administered, it is necessary that the operation of the peristaltic pump be precisely controlled to infuse only a predeternined volume of fluid at a predetermined rate. Thus, the need has developed for a control system for peristaltic-type infusion pumps which enables the operator to preset a quantity and rate of infusion, and which continuously monitors the performance of the pump to insure compliance with the pre-set parameters bv interrupting operation and alerting the operator in the event of a malfunction. Furthermore, it is lS ` desirable that the system be fail-safe, and substantially unaffected in operation or accuracy by power line interruptions or transients. The metering apparatus of the present invention provides these features in an integrated unit which is simple and convenient to use.
Accordingly, it is a general object of the present invention to provide a new and improved system for infusing fluids into the human body.
It is a more specific object of the present inven-tion to provide a new and improved metering apparatus for use in conjunction with an administration set for infusing fluids :
into the human body.
According to the present invention there is provided a fluid metering apparatus for controlling the flow of fluid through the tubing of a fluid aaministration set, the apparatus having a housing with a rotor mounted on the housing for rotation about a fixed axis, the rotor including a plurality of pressure rollers disposed about the circumference thereof. Means is provided, including a pressure plate disposed adjacent the circumference of the rotor so that a segment of the tubing is positioned in compressive engagement with the pr~ssure rollers and fluid is caused to flow through the tubing with rotation of the rotor. Flow restriction means is provided which includes a slidably mounted plunger spring-biased against the tubing for occluding the tubing at a predetermined location downline of the tubing segment to increase the pressure of the fluid in the tubing segment.~ The position of the plunger with respect to the housing varies over a predetermined operating range with the pressure of the fluid in the tubing. There is provided means for rotatably driving the rotor, and occlusion detection means is provided which includes electric switch means operatively engaged with the plunger and responsive to the position thereof in the operating range for interrupting rotation of the rotor upon movement of the plunger to a predetermined position in the operating range corresponding to a predetermined partial occlusion of the tubing by the plunger.
9g BRIEF DESCRIPTION OF THE DRAWINGS
... .. _ The features of the present invention which are believed to be novel are set forth with par-ticularity in the appended claims. The invention, together with the further objects and advantages -thereof, may best be understood by reference to the following description taken in conjunction with the accompanying drawings, in the several figures of which like reference numerals identify like elements, and in which:
Figure 1 is a perspective view of an infusion metering apparatus constructed in accordance with the invention.
Figure 2 is an exploded perspectiv~ view showing the principal components oE the metering apparatus housing.
Figure 2a is a cross-sectional view of the metering apparatus taken along line 2a-2a of Figure 1.
Figure 3 is an enlarged front elevational view of the peristaltic pump utilized in the metering apparatus of Figure 1 broken away to show the rotor and downline occlusion 9~9 stations thereof.
Figures 3a and 3b show the do~nline occlusion station of the pump as seen in Figure 3 in alternate positions.
Figure 4 is a cross-sectional view of the pump ta~:en S along line 4-4 of Figure 3.
Pigures 4a and 4b show the latch member of the do~;n-line occlusion station as shown in Figure 4 in alternate positions.
Figure 5 is an enlarged e~ploded perspective view of the principal components of the fluid metering station of the metering apparatus.
Figure 6 is a simplified functional blocX diagram of the control system incorporated in the metering apparatus of the invention.
lS Figure 7 is a functional block diagram partially in schematic form of the control system.
Figure 8 is a simplified schematic diagram of the bubble detector utilized in the fluid metering apparatus of the invention.
!O Figure 9 is a simplified schematic diagram of the power supplies utilized in the fluid metering apparatus of the invention.
Description of the Preferred Embodiment Referring to the Figures, and particularly to Figure 1, 2 peristaltic-type flow metering system 10 for use in con-~149~
junction with an administration set for controllina the flo~
of fluid into a vein or axtery includes a generally rectangular housing 12 havins a handle 13 at one end thereof for con-venient carrying. The front surface of the housing includes a eontrol panel 14 which allo~s the operator to control anc monitor the operation of the metering a~paratus, and a peri-staltie-type flow metering head 15 for compressing a section of tubing 16 of the administratio~ set to effect control of fluid flow therein. A channel 17 is provided above the metering head 15 for maintaining a portion of the tubing segment in A eonvenient view of the operator whereby flow irregularities ean be more readily observed.
The administration set, of whieh tubing segment 16 is a part, and whieh may be eonventional in design and eon-struetion, is preferably formed of a plastie material such as vinyl and paekaged in a sterile and non-pyrogenie eondition.
To avoid the danger of eontamination, the administration set is normally utilized for one applicatior. only, and is disposed of after use.
The operating mode of the metering apparatus is controlled by means of a push button STOP switeh 20, a push button START switeh 21, and a push button power ON-OFF switeh 22. Eaeh of these push button switches ineludes an internal indieator lamp whieh provides a positive indieation of the ~5 operating mode of the apparatus.
9~3 Various abnormal operating conditions are annunciated by means of in~icator lights 23-27 containec or.
the control panel to the left (as vie~ed in Figure 1) of the mode control push buttons. The operation of these indicator lights ~ill be explained in conjunction ~iit~ the operation of their respective systems within the metering apparatus.
Control panel 14 further includes a digital dis-play 30 of volume infused, a di~ital display 31 of volume to be infused, and a digital display 32 of the fluid flow rate. The volume displayed by display 30 is the volume of fluid actually infused, and can be reset to O by the operator by means of a push button RESET switch 33. Ihe volume to be infused by display 31 is preset by the operator L5 by means of a set of push button switches 34 to indicate a desired volume of fluid to be infused. Similarly, the infusion rate display 32 is preset by the operator by means of a second set of push button switches 35 to indicate the rate at which infusion is to take place.
'O As shown in Figures 2 and 2a, to provide an aes-thetically pleasing front panel surface free of openings which might harbor contaminants, the front panel 14 is preferably constructed from a single seamless panel 36 having necessary transparent sections 37 for viewing readouts 30, 31 and 32.
The push button switches 33-35 associated with these displays 9~
are preferably pressure-sensitive s~-itches, which respond to very s~all deformations of the front panel brought about by finger pressure from the operator to actuate their re-spective circuits. The pressure-sensitive s~-itches are mounted on one side of a printed wiring board 38 behin~
panel 36, with connections fro~ the board e~tending through apertures in the housing to a printed wiring board 28 within the housing. Additional individual system wiring boards 29 are plugged into sockets contained on this board. A plurality of metallic screen panels 39 may be provided between board 38 and housing 12 for the purpose of providing radio fre-quency interference (RFI) shielding for the electronic circuitry of the metering apparatus.
Referring to Figure 3, the peristaltic metering head 15 includes a rotor 40 having four pressure rollers 41 disposed in equi-spaced relation about its circumference.
The rollers are each mounted on a shaft 42 for free rotation thereon, and the shafts are carried on carriages 43 and con-strained to radial movement by respective radial slots 44.
Each carriage 43 is mounted for reciprocation within a radially aligned recess 45 and spring loaded in a radially outward direction by a helical spring 46 disposed within the recess.
The pump also includes a pressure plate S0 having an arcuate working surface 51 which substantially corres-ponds in sha~e to the circumference of the pump rotor a~d is positioned to bring the tuhing segment 16 into co~preC-sive engagement with rollers 41 around at least a porticr of the rotor circumference extending between adjacent rollers. The pressure plate may be reciprocated tohard and away from rotor 40 tc facilitate installation and re-~oval of tubing segment 16 by rotation of an eccentric cam 52, which is constraine~ to operate within a ~ertical slot 53 provided on the pressure plate. Rotation of the cam is accomplishe~ by a shaft 54 and user-actuable lever 55 operatively connected to the cam. When the lever 55 is in its bottom position, as shown in Figure 3, the pressure plate is moved sufficiently close to the rotor circumference to cause tubing seg~ent 16 to be completely occluded by the L5 rollers. Since each of rollers 41 is individually biased into engagement with the tubing segment, the pressure applied by each roller is independent of the number of rollers engaging the tubing segment.
After passing through the peristaltic metering !0 station, tubing segment 16 extends between a light source 60 and a photodetector 61, which together comprise a bubble detector station 62. ~s will be seen presently, it is the function of this statioD to discontinue operation and alert the operator upon formation of a bubble in the tubing segment.
Referring to Figures 3-5, the tubing next passes through a flow restriction station 63. This station in-cludes a pressure block 66 and a slidably ~ounted flo~ re-striction plunger 67 biased asainst the side~all of ~u~ing segment 16. The end of plunger ~7 ~hich engages the tubir.
S segment includes a generally L-shaped hea~ portion 68 having a wedge-shaped working surface 7C and a generally flat control surface 71. Plunger 67 includes a central body portion which is slidably received within a stationary mounting block 73, and which extends through the center of a helical compression spring 74 provided for biasing head 68 into engagement with tubing segment 16.
The working surface 70 o head portion 68 bears against the sidewall of tu~ing segment 16 substantially perpendicular to the direction of fluid flow within the .5 tubing as the tubing is held in posi~ion against pressure block 66, As a result, the lumen of the tubing segment is occluded at the point of engagement, and a downline conduit segment is defined between the point of engagement of the rollers 41 and the point of engagement of the wedge-0 shaped working surface 70. As previously developed, the occlusion of the tubing in this way increases the pressure of the fluid in the tubing segment and prevents separ-` ation of dissolved gases therein.
The control surface 71 of plunger 67 extends substantially parallel to the direction of fluid flow ,, ~ .
. : -3g and is substantially greater an area than the wor~ing surface 70. The relatively large area of the contrcl surface 71 renders the plu~ger more sensitive to pres-sures in t~.e tubing lumen when the p~p is operative so that higher pressures can be exerted by spring 74 to more positively close off the tubinq when the pump is not in operation, without ~etriment to its ability to open at lower operating pressures.
Plunger 67 may be opened to facilitate load-ing or unloading of tubing segment 16 by means of a user-actuated lever 76 mounted for reciprocation with plunger 67. The plunger is constrained to reciprocation along a defined operating path by the stationary mounting block 73 which is mounted to the apparatus housing 14. The helical compression spring bears against this mounting block at one end and against the head of the plunger at its other end, causing the desired bias of the plunger against the tubing segment.
Automatic release cf the plunger is obtained by means of a latch member 77 which is pivotably mounted at 78 to pressure plate 50 and biased by a helical spring 79 for operation within a plane perpendicular to the plunger. The plunger includes a slot 80 in which the latch member 77 is received when the plunger is moved to its `5 full open position, as shown in Figure 3b. The end 81 .
of the plunger may be tapered to facilitate displacement of the latch member prior to seating in slot 80. Once the latch member has been received in the slot, the plunger is locked open and the tubing segment 16 can be readily removed.
To insure that plunger 67 will be released when pressure plate 50 is subsequently closed, mounting block 73 is provided with an actuator pin 82. As shown in Figures 3 and 4, this actuator pin has a tapered end surface 83 which serves to displace the pivotably mounted latch member 77 from slot 80 when the pressure plate is returned to its closed position by rotation of knob 55. In this way, the plunger is automatically released so as to again become spring-biased against the adminis-tration set tubing segment 16 as the metering station is closed. This prevents inadvertent operation of the system without the back pressure and gravity flow pro-tection provided by the plunger. Also, when the pres-sure plate is open, the displacement of latching member 77 prevents the plunger from being latched open. A gate member 84 adjacent the control surface 71 of plunger 67 prevents the tubing segment from being inadvertently pulled free of the compression plunger during operation.
By reason of the tubing segment 16 being held in a highly visible vertical position within channel 17 the flow of fluid therethrough can be readily monitored. Furthermore, this channel obviates the need for additional tubing clamps at the inlet and outlet portions of metering head 15 while at the same time providing an aesthetically pleasing structure on the pump housing.
The above-described metering apparatus including the latching arrangement is also described and is claimed in above-identified Patent Application Serial No. 316,257.
Referring now to Figure 6, the control system for metering apparatus 12 is seen to include a stepper motor 100 which is rotatably coupled to rotor 40 so as to drive the rotor one increment for each step command applied to the motor. To supply the multi-phase signals required for operation of the stepper motor the metering apparatus includes multi-phase motor drive circuits 101 which respond to an applied control pulse to generate a multi-phase output signal which steps~the motor one increment. The control pulses are generated by a variable rate divider 102 which produces an output signal after a predetermined number of input pulses have been received from a continuously running clock 103. The divider, which may be conventional in design and construction, is preset by the user to a desired division rate which is displayed by an associated display device 104. In this way, by setting different division factors into the variable rate diviser 102, the stepper motor can be operated over a wide range of rotational speeds.
To provide a display indicative of the total volume of fluid infused a register 105 responsive to the output pulses fxom divider 102 is provided. The counting state of register 105, and hence the volume : infused,-is displayed by a display device 106. The output pulses from divider 102 are also applied to a register 107 having an associated display device 108. This register is a bi~directional register, which prior to use of the metering apparatus is counted up to a counting state corresponding to the quantity of . fluid to be infused, and then during use is counted down with infusion of the fluid until a zero counting state is reached. At this time the register generates lS an output signal which disables a gate 109 to inter-rupt application of control pulses to motor drive circuits 101.
The control system.of the flow metering ap-paratus 10 is shown in greater detail in Figure 7. ~ere the dlvision factor of variable divider 102, and hence the fluid infusion rate, is seen to depend on ~he counting state of a register 110. This counting state can be con-veniently set by the user by means of the rate setting switches 35 which enable respective NOR gates 112 to supply pulses to the register from a pulse source 113.
1~3~9~
In practice, several NOR gates and rate setting switches are provided to allow each digit of the register to be independently set. The counting state of register 110 is displayed by display device 104 as an indication of S the metering or infusion rate of the apparatus.
The output of register 110 is applied to a co~pari-son circuit 114 wherein the register counting state is com-pared with a predetermined fixed minimu~ rate, typically S ml. per hour, to determine whether the infusion rate es-tablished by divider 102 is greater than or less than the minimum rate. In the event that the desired rate is greater than the minimum rate, comparison circuit 114 produces an out~
put signal which enables NAND gate 115 to provide for establish-ment of a minimum "keep open" rate after the desired quantity of fluid has been infused. To this end, the output of clock 103 is applied to a fixed divider 116 which provides output pulses at a fixed minimum "keep open" rate. These pulses are applied to a NOR gate 117 and, depending on the state of this gate, to an OR gate 118 for application to the motor drive circuits 101. The "keep open" mode is operative only after the desired quantity of fluid has been infused, as signaled by the bi-directional register 107 reaching a zero counting state.
The output signal generated by register 107 upon reaching a zero counting state is applied to the remaining ~3~
input of NAND gate 115 and ~o one input of a NOR gate 119. As a result, NOR gate 119 is inhikited and the application of pulses from variable divider 102 is interrupted. Should N~D
` gate 115 be enabled as a result of the variable rate being S greater than the predetermined minimum flow rate,the zero state output signal from register 107 is applied through an in-verter 120 to a keep open indicator 24 and to an input of NOR gate 117, wherein it serves as an enabling signal. This gate, when enabled, allows the fixed rate pulses from the fixed rate divider 116 to be applied to OR gate 118, and hence to motor drive circuits 101. In this way, a minimum flow rate is maintained even after the desired quantity has been infused.
To provide start-stop control over stepper motor 100 the remaining inputs of NOR gates 117 and 119 are con-lS nected to the output of a start-stop flip-flop 121. This flip-flop may be conditioned to a start state by actuation of the push button START switch 21, or to a stop state by actuation of the push button STOP switch 20, or by occurrence of any one of a number of abnormal conditions, including 'O interruption of power, detection of a bubble in the adminis-tration set, detection of an occlusion in the administration set, or the opening of the metering head pressure plate while the metering apparatus is in operation.
To pxovide an accurate indication of the volume of fluid actually infused, the output of OR gate 118 is ~U3~
applied to a fixed divider stage 122 wherein a constant division factor is applied to generate one output pulse for each milliliter of fluid infused. In practice) where stepper motor 100 is required to step 2,352 times to pump 1 milliliter through tubing segment 16, divider 122 may be set to diviQe by 2,352 to obtain the desired volume-indicative output signal.
This output signal is applied to register 105 wherein it advances the counting state of the register so tha~ the in-stantaneous counting state thereof indicates the volume of fluid actually infused. As previously stated, this volume is displayed by display device 105.
The volume-indicative output pulses from divider 122 are also applied through an OR gate 123 to the stepping input of bi-directional register 107 wherein they cause that L5 register to count down one step toward zero with each milli-liter passing through the system. As stated previously, the counting state of register 107, and hence the volume of fluid to be infused, is displayed by display device 108.
Prior to use of the infusion metering apparatus, ~0 the counting state of regis~er 107 is preset by the user by momentarily applying pulses to the register from pulse source 113. This is accomplished through c NOR gate 124 which is enabled by the operator by actuation of the SET VOLUME switch 34. In practice, one such switch and NOR gate are provided !5 for each decade of the counter. The remaining input of NOR
gate 124 is connected to the output of the start-stop flip-flop 121 to prevent the volume display from being changed while the metering apparatus is in operation.
Register 107 is capable of counting either u~ or down depending on an applied mode control signal. This signal is developed from the output of start-stop flip-flop 121 by means of an inverter 125 so as to oondition register 107 to count up with application of set pul~es from source 113 ~hen the apparatus is stopped, and to count down with application of volume-indicative pulses from divider 122 when the metering apparatus is in operation.
Prior to initial operation of the metering apparatus register 105 is reset by the operator by actuation of push .5 button RESET switch 33. This switch is connected to one in-put of an AND gate 126, the other input of which is connected to the output of the start-stop flip-flop 121 to render the reset switch 33 non-functional while the metering apparatus is in operation. The output of AND gate 126 is applied 0 through an OR gate 127 to the reset inputs of register 106 and divider 122. In this way, the divider and register are simultaneously reset to a zero counting state prior to initial operation of the apparatus.
An auto reset state 130 responsive to initial applica-S tion of power to the apparatus is provided to automatically establish ;
an initial counting state in registers 10r, 107 an~ 110. ~he output of the auto reset stage is applie~ to the remain.ng input of OR gate 127 so as to establish a zero counting state in register 105 and divider 122, and to the reset input Gf register 110 through A~D gate 131. Should the operator atter~pt to set the most significant digit of register 110 above 4, a reset circuit coupled to the remaining input of AND gate 131 also resets the register. In this way the setting of infusion rates in excess of 455 ml. per hour is prevented.
The output of the auto reset stage is also applied to register 107, ~herein it establishes a ~inimum counting state of 1 ml.
to prevent initiation of the "keep open" mode before the metèring apparatus has been placed in operation.
Operation of the infusion metering apparatus is interrupted upon occurrence of an occlusion within the ad-ministration set, as detected by a switch 132 associated with plunger 67 (Figures 3 and 5). This switch, which may be a pressure switch similar to switches 33-35, or a magnet-ically-actuated Hall-effect switch, is actuated by an actuator ~0 lever attached to the plunger when the plunger is allowed to close against the tubing as a result of an occlusion with-in the administration set. The switch provides an output signal which actuates a latch circuit to condition start-stop ~lip-flop 121 to a STOP state and illuminate occlusion indi-'5 cator lamp 25.
,. .
~3~
Operation of the apparatus is also interrupte~.
in the event of a bubble being detected at bubble detector 6~. In this event, an output signal is generated by the bubble detector ~hich actuates a latch circuit to con~itiGr i the start-stop flip-flop 121 to interrupt operation of the metering apparatus. At the same time, B~B~L~ indicator lamp 23 is illuminated to alert the operator.
Operating power for the fluid metering apparatus is supplied by means of two unidirectional current supplies .0 135 and 136 ~thich receive operating power from the AC line through ON-OFF switch 22. A battery 138 is provided as an additional source of operating power in the event of failure of the AC line. The battery is connected through s~itch 22 across the output of power supply 135.
Normally, battery 138 is maintained charged by power supply 135 and the various control circuits of the infusion metering apparatus are powered by this combined : source, while the stepper motor 100 is powered by the power supply 136. To guard against interruption of AC line voltage \
0 the output of the power supply 135 is continuously monitored by a voltage comparator 140. Upon occurrence of a line voltage interruption an output signal is produced by comparator 140 which simultaneously illuminates a BATTERY ON indicator 26 and actuates a relay 141.
; Operation of the metering apparatus is interrupted . -20-,,, . ~ , .
~3~ ;9~
whenever the battery voltage falls below a predetermined minimu~ level for a predetermined period of time. To this end, the battery voltage is continuously monitored by a voltage comparator stage 133. ~pon occurrence of a lo~
voltage condition, an output signal is produced which ac~
tivates a latch circuit to illuminate the B~TTERY LOI~, la~p 27 and initiate operation of a timing ccunter 134. This counter counts the "keep open" output pulses developed by ~ixed divider 116 to obtain a 10 minute time delay. If the low voltage condition persists beyond this delay period an output signal is developed by timing counter 1~4 which causes the 8ATTERY LO~- lamp to flash and conditions start-stop flip-flop 121 to interrupt operation of the metering apparatus.
It should be noted that the operation of comparator 133 is lS entirely independent of comparator 140, and serves as a check on system voltage whether supplied by power supply 135 or battery 138.
Stepper motor 100 is powered by power supply 136 -through transfer contacts on xelay 141. The purpose of these~
~0 contacts is to substitute battery 138 as a source of power for the stepper motor in the event of an AC linè ailure as detected by comparator 140. The various phase windings of motor 100 are individua~lly supplied from power supply 136 by means of switching transistors 142-145 connected in series with the windings.
.~ , . . . .
,.f In accordance with another feature of the apparatus, isolation is obtained between step~er motor 100 ar.~ the pulse-sensitive control circuits of the ~etering apparatus by means of individual optical isolators 146-14q associated with re~
5 spective ones of the switching transistors. Each of the optic~l isolators includes a light detecting ele~;ent connected between the motor current source and a respective one of the switching transistors, and a light e~!itting diode (LED) element connected to the output of a respective one of inverting am-10 plifiers 150-153. These amplifiers receive phase control signals fro~. motor drive circuits 101 through respective NOR gates 154-157 which serve as a safety shutoff control means for the metering apparatus.
The NOR gates 154-157 are disabled when the start-15 stop flip-flop 121 is conditioned to a stop mode by means of an OR gate 158 having an output connected to one input of each of the I~OR gates. Also, these NOR gates can be dis-abled by outputs from bubble detector 62 and occlusion switch 132 through an additional OR gate 159 ~hich provides an 20 ~dditional input to OR gate 158. Thus, occurrence of an occlusion, detection of a bubble, or conditioning of the start-stop flip-flop to a stop state for any reason causes the interruption of control signals to optical isolators 146-149 and interruption of drive power to stepper motor 100.
~S In operation, the user initially sets an infusion ~33L~9~
rate by actuating switch 35 t~ apply a requisite n~m~er of pulses to re~ister 110. The counting state of this register sets the variakle divider 102 such that control pulses are developed at the output thereof with a repetition rate com-mensurate with the desired infusion rate. These control pulses are applied through NOR gate 119 to the motor drive circuits 101 wherein they are utilized to generate multi~le phase control signals suitable for controlling the operation of the multi-phase stepper motor 100. Each of the phase signals developed by drive circuits 101 is applied through a respective one of NOR gates 154-157 and inverter amplifiers 150-153 to a respective one of optical isolators 146-149.
These isolators in turn control conduction in respective ones of drive transistors 142-145 to apply current from p~wer supply 136 ~o stepper motor 100. In this way, the stepper motor turns the peristaltic rotor 40 at a rate es-tablished by the operator.
To provide a continuous readout of fluid vo~ume infused the dri~e pulses applied to the drive circuits 101 are also applied to divider 122 to develop pulses indicative of the number of complete milliliters infused. These pulses are counted by register 105 to provide a display in device 106 indicative of the actual quantity of fluid infusPd.
Prior to initial operation of the apparatus an initial counting state is established in register 107 by . ~ .
9~
momentary application of pulses from pulse source 113 through NOR gate 124 and OR gate 123 to esta~lish an initial counting state indicative of the total volume of fluid to be infused.
Register 108 is conditioned to count up at this time by i start-stop flip-flop 121 through inverter 125.
Once this volume is set, operation is started by actuation of switch 21 and register 107 is conditioned to count down by flip-flop 121. Pulses from divider 122 indi-cative of actual volume infused are now applied through C~
0 gate 123 to count register 107 down toward zero. When the register reaches a zero countin~ state, indicating that the desired volume of fluid has been infused, an output signal from register 107 inhibits NOR gate 119 and prevents further operation of stepping motor 100 by pulses from the variable ; divider 10~. However, should the rate established by vari-abJ.e divider 102 be greater than a predetermined minimum infusion rate, comparison circuit 114 provides an enabling signal to NAND gate li5 which allows the output signal from register 107 to enable NOR gate 117 through inverter 120.
This establishes a "keep open" mode of operation wherein pulses from fixed divider 116 provide motor drive circuits 101 with stepping command signals at a frequency which maintains a desired minimum flow rate through the system.
Registers 106, 107 and 110 are automatically reset upon initial operation of the system by the auto reset cir-,:.
. .
~3~99 cuit 130. Register 105 may also be manually reset by stitch 33 when the start~stop flip-flop 121 is conditione~
to a stop state.
Protection against occlusion in the administrat~on set is provided by s~Titch 132, which conditions flip-flGp 121 to a stop state and inhibits AND gates 154-157. ~imilarl~, protection against the formation of bubbles within the ad-ministration set is provided by bubble detector 62, which also conditions flip-flop 121 to a stop state and inhibits AND gates 154-157. Protection against AC line failure is provided by voltase comparator 140 ~7hich actuates relay 141 to switch stepper motor 100 to battery 138, and by voltage comparator 133 which interrupts operation of the apparatus upon occurrence of a low voltage condition for a predetermined period of time.
Upon occurrence of any one of the above alarm functions, or upon infusion of the desired fluid volume, an aural alarm 160 is actuàted to alert the operator that attention to the apparatus is required. A s~itch associated with the pressure plate of the pump head locks out the alarm when the pump head is opened.
Referring to Figure 8, the bubble detector 62 of the infusion apparatus includes an AC-powered detection circuit which offers improved detection sensitivity and stability.
Basically, the detection circuit, as shown in Figure 8, comprises a multi-vibrator 161 consisting of three NA'~D
gates 162, 163 and 164. A capacitor 165 connected to the output of gate 163 and a potentiometer 166 connected to the output of gate 164 provide an RC time constant which determine the fre~uency of the multi-vibrator output signal in a manner well ~no~n to the art. A diode 167 is connected between the arm of potentiometer 166 and the output of gate 164 to vary the duty cycle of the oscillator output signal.
A fixed impedance 168 connected in series ~7ith the body of potentiometer 166 provides a desired adjustment range.
The AC signal generated by multi-vibrator 161 is applied through an impedance 169 to the base of a transistor 170. The emitter of transistor 170 is connected to ground and the collector is connected to the cathode of a light emitting diode ~LED) which comprises the light source 60 disposed on one side of the administration set tubing seg-ment 16. The anode of the LED is connected to a source of positive unidirectional current through a resistor 171. As a result, the AC signal developed by multi-vibrator 161 is amplified by transistor 170 and utilized to drive the LED, causing the LED to produce a light output which varies at a rate dependent on the output fre~uency of the multi-vibrator.
The altèrnating light developed by the LED is detected by photodetector 17~ and associated amplifier transistor 173, which together comprise the light detector :
~3~9~
61 adjacent tubing segment 16. The collectors of photo-detector 172 and transistor 173 are connected to the positive unidirectional current source of the apparatus, an~ the emitter of detector 172 is connected to the base of transistor 173. The emitter of transistor 173 is connected to ground throu~h a resistor 174 and through respective diodes 175-177 to respective inputs of a dual Schmitt trigger 178. The cathodes of diodes 175-177 are connected to ground by respective ones of capacitors 180-182 and re-sistors 183-185 in parallel circuit configuration. These elements serve in conjunction with the 2iodes a signal de-tector, ger.erating a DC signal at the inputs of trigger 178 dependent on the amplitude o the AC signal produced by de-tector 61. Trigger 178, which may be a commercially avail-able component such as a type MC14583B marketed by Motorola, produces an output upon reduction belo~ a predetermined threshold level of the DC signal developed at either of the inputs associated with diodes 176 and 177. The input associated with diode 175 functions as an enabling input for both triggers. The output of Schmitt trigger 178 is applied to one input of an OR gate 179.
The emitter of transistor 173 is also connected to ground through series-connected resistors 186 and 187.
The signal developed at the junction of the two resistors ~5 is filtered by a series connected resistor 188 and a , cap~citor 189 and parallel connected resistor connected to ground and applied to the remairing input of OR gate 179.
In this way OR gate 179 is provided with the output signal developed by the two Schmitt triggers 178 and a DC control sisnal developed across capacitor 189, either of which can result in a bubble-indicative output from the gate in ~he ~event of a bubkle occurring in tubing segment 16. The out-put of Schmitt triggers 178 and the output of OR gate 179 are also connected to the positive unidirectional current source of the system by respective resistors.
Since the output of OR gate 179 is dependent on both the amplitude of the AC signal as rectified and applied to the parallel-connected Schmitt triggers 178, and on the DC signal developed across capacitor 189, the bubble de-LS tector utilized in the metering apparatus provides two in-dependent control channels. The first channel, which utilizes Schmitt triggers 178, astablishes a hignly precise threshold below which an alarm output is produced. The second channel, which depends only on the input characteristic of !0 gate 179 and is less precise, serves as a backup in the event of failure of the Schmitt triggexs in an active mode.
In order for bubble detector 62 to not provide an output, it is necessary that the DC signals applied to the Schmitt triggers as a result of rectification by diodes 176 and 177 be above a predetermined minimum level, which -28~
, ., , ;
1~3~9~
is possi~le only when there is flui~ ~,ithin tubing segment 16 which acts as a lens to direct light from light source 60 to detector 172. In the event o~ failure of the light source or the detector, or any other component of the syste~, the DC signal applie~ to the Schmitt triggers is removed ard an alarm output is generated. In the event of failure of the Sc~itt triggers, an alarm output will be developed ~y OR gate 179 upon loss of the DC signal from capacitor 189.
Th~ use of an AC signal eliminates drift in the circuitry as a factor affecting the threshold level of the Schmitt triggers, thereby allowing the threshold to be set closer to the normal operating level of the system for greater detection efficiency.
Transient spikes on the AC line, which are parti-cularly prevalent in institutions such as hospitals ~here lS electrical machinery is in operation, introduce the potential of spurious counts in the digital registers and gates utilized in the control circuits of the metering apparatus.
For this reason, it is imperative that the greatest possible isolation be provided by power supplies 135 and 136 between the control circuits and the AC line, particularly in view of the possibly critical life-determining nature of the metering apparatus.
To this end, separate power supplies each incor-porating special transient protection features are provided ~5 in the metering apparatus. Referring to Fiyure 9, it is ~L~31a~
seen that the two po~er supplies 135 and 136 share a co~mor.
power transformer 190 which includes individual secondary indings 191 and 192 each electrostatically shielded from the line. The output of secondary winding 191 is connected across a bridge rectifier lq3 within power supply 136. The positive polarity output of bridge rectifier 193 is connected to the positive polarity input terminal 194 of a first four-texminal filter capacitor 195. The negative input terminal 196 of this capacitor is connected to the negative polarity output of the bridge rectifier.
Filter capacitor 195 is an electrolytic type capacitor which includes four terminals; a first pair of terminals associated with respective ends of the positive plate of the capacitor, and a second pair of terminals lS associated with respective ends of the negative or foil side of the capacitor.
The output terminals 197 and 198 of capacitor 195 are connected to a conventional voltage regulator circuit which includes a series-connected regulator transistor 200.
In a manner well known to the art, the conduction state of transistor 200 is varied in response to the voltage level existing at the output of power supply 136 so as to maintain the voltage level constant. To this end, a zener diode 201 ànd resistor 202 are connected across the output electrodes of the capacitor to develop a reference voltage. This ~3~
reference voltage is compared within a comparator amplifier 203 ~ith a portion of the output voltage of the po~er supply as developed by a potentiometer 204 connected acrccs the output terminals of the supply. The output of compara-tor 203, representing the deviation of the output volta~e from a reference level, is applied to a transistor 205 ~hich serves to amplify the erxor signal prior tc applica-tion to the base of transistor 200. Additional regulation to compensate for changes in current load is provided by a series-connected resistor 206 at the emitter of transistor 200. This register develops an additional error signal ~hich is applied through three series-connected voltage dropping diodes 207 to the base of the error amplifier transistor 205. Protection against transient spikes is provided by reverse-biased diodes 208 and 209 connected across the input and output leads of the voltage regulator, respectively.
Power supply 135, which is virtually identical to power supply 136, includes a bridge rectifier 210 con-nected across secondary winding 192, and a four terminal ~ilter capacitor 211 having input terminals 212 and 213 connected across the output of the bridge rectifier. The output terminals 214 and 215 of the capacitor are connected to a series regulator circuit similar to that contained in power supply 136, including a series regulator transistor , ~3~
216, a voltage refe~ence zener diode 217 an~ a diffexential amplifier 218 with similar functions. ~ filter capacitor 220 is connected across the output of the power supply to provide additional filterin~.
~he described power supply arrangement has the a~-vantage of providing a high degree of filtering between the AC line and the respective power supply busses of the meter-ing apparatus. The four-terminal filter capacitors are particularly effective in this respect, in that any transient currents attempting to enter or leave the respective power supplies must pass through the electrodes of the capacitor, since these electrodes are relie~ upon to complete the metallic circuit. As a result, the filtering action of the capacitors is not reduced with transients of higher frequencies, as ~ n conventional filter capacitors.
The use of separate power supplies, each utilizing the four-terminal filter capacitor component, provides a very high degree of isolation between the stepper motor circuit and the digital control circuitry of the metering apparatus.
This is desirable because of the relatively high switching transients inherent in the operation of a stepper motor, and the possibility of these transients affecting the critical digital control circuitry.
Thus, the invention provides a flow metering appar-atus for fluid infusion systems which allows ~he operator to ~3~9~
directly select fluid flow rate and volume ~ithout the nee~
- for calculations.- The apparatus is convenient to install and does not require particular skills on the part of the operator for its operation. Protection is provided wit~n the apparatus against malfunctions in the administratior set and with the apparatus itself, in the event of which the operator is signaled and operation of the apparatus is terminated. The apparatus is portable and of a construction which lends itself to convenient use in a hospital environ-ment.
While a particular emkodiment of the invention has been shown and described, it will be obvious to those skilled in the art that changes and modifications may be made therein without departing from the invention in its broader aspects, and, therefore, the aim in the appended claims is to cover all such changes and modifications as fall within the true spirit and scope of the invention.
Claims (4)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. Fluid metering apparatus for controlling the flow of fluid through the tubing of a fluid administration set, comprising:
a housing;
a rotor mounted on said housing for rotation about a fixed axis, said rotor including a plurality of pressure rollers disposed about the circumference thereof;
means including a pressure plate disposed adjacent the circumference of said rotor whereby a segment of said tubing is positioned in compressive engagement with said pressure rollers and fluid is caused to flow through said tubing with rotation of said rotor;
means for rotatably driving said rotor;
flow restriction means including a slidably mounted plunger spring-biased against said tubing for occluding said tubing at a predetermined location downline of said tubing segment to increase the pressure of said fluid in said tubing segment, the position of said plunger with respect to said housing varying over a predetermined operating range with the pressure of said fluid in said tubing;
occlusion detection means including electric switch means operatively engaged with said plunger and responsive to the position thereof in said operating range for interrupting rotation of said rotor upon movement of said plunger to a predetermined position in said operating range corresponding to a predetermined partial occlusion of said tubing by said plunger.
a housing;
a rotor mounted on said housing for rotation about a fixed axis, said rotor including a plurality of pressure rollers disposed about the circumference thereof;
means including a pressure plate disposed adjacent the circumference of said rotor whereby a segment of said tubing is positioned in compressive engagement with said pressure rollers and fluid is caused to flow through said tubing with rotation of said rotor;
means for rotatably driving said rotor;
flow restriction means including a slidably mounted plunger spring-biased against said tubing for occluding said tubing at a predetermined location downline of said tubing segment to increase the pressure of said fluid in said tubing segment, the position of said plunger with respect to said housing varying over a predetermined operating range with the pressure of said fluid in said tubing;
occlusion detection means including electric switch means operatively engaged with said plunger and responsive to the position thereof in said operating range for interrupting rotation of said rotor upon movement of said plunger to a predetermined position in said operating range corresponding to a predetermined partial occlusion of said tubing by said plunger.
2. Fluid metering apparatus as defined in claim 1 wherein said occlusion detection means are actuated to interrupt movement of said rotor upon substantially complete occlusion of said tubing by said plunger.
3. Fluid metering apparatus as defined in claim 1 wherein said plunger includes a wedge-shaped working surface of relatively low contact area with said tubing segment for occluding said tubing and a control surface of substantially greater contact area with said tubing segment for positioning said plunger in response to fluid pressure changes within said tubing.
4. Fluid metering apparatus as defined in claim 3 wherein said plunger is spring biased against said tubing with sufficient force to substantially completely occlude said tubing in the absence of fluid pressure therein.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA388,045A CA1131499A (en) | 1977-12-02 | 1981-10-15 | Metering apparatus for a fluid infusion system with flow control station |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/856,926 US4210138A (en) | 1977-12-02 | 1977-12-02 | Metering apparatus for a fluid infusion system with flow control station |
US856,926 | 1977-12-02 | ||
CA316,257A CA1127003A (en) | 1977-12-02 | 1978-11-15 | Metering apparatus for a fluid infusion system with flow control station |
CA388,045A CA1131499A (en) | 1977-12-02 | 1981-10-15 | Metering apparatus for a fluid infusion system with flow control station |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1131499A true CA1131499A (en) | 1982-09-14 |
Family
ID=27165981
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA388,045A Expired CA1131499A (en) | 1977-12-02 | 1981-10-15 | Metering apparatus for a fluid infusion system with flow control station |
Country Status (1)
Country | Link |
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CA (1) | CA1131499A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112243563A (en) * | 2018-06-26 | 2021-01-19 | 三美电机株式会社 | Rotary reciprocating drive actuator |
-
1981
- 1981-10-15 CA CA388,045A patent/CA1131499A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112243563A (en) * | 2018-06-26 | 2021-01-19 | 三美电机株式会社 | Rotary reciprocating drive actuator |
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