CA1050966A - (16.alpha.,17-B) 1,4 DIOXANES DE STREROIDES - Google Patents

(16.alpha.,17-B) 1,4 DIOXANES DE STREROIDES

Info

Publication number: CA1050966A
Authority: CA; Canada
Prior art keywords: hydrogen; fluoro; accordance; steroid; dione
Prior art date: 1974-01-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA217,981A

Other languages

English (en)

Other versions

CA217981S (en

Inventor

Christopher M. Cimarusti

Seymour D. Levine

Frank L. Weisenborn

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ER Squibb and Sons LLC

Original Assignee

ER Squibb and Sons LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-01-16

Filing date

1975-01-15

Publication date

1979-03-20

1975-01-15 Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC

1979-03-20 Application granted granted Critical

1979-03-20 Publication of CA1050966A publication Critical patent/CA1050966A/fr

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA217,981A 1974-01-16 1975-01-15 (16.alpha.,17-B) 1,4 DIOXANES DE STREROIDES Expired CA1050966A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US43397474A	1974-01-16	1974-01-16

Publications (1)

Publication Number	Publication Date
CA1050966A true CA1050966A (fr)	1979-03-20

Family

ID=23722311

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA217,981A Expired CA1050966A (fr)	1974-01-16	1975-01-15	(16.alpha.,17-B) 1,4 DIOXANES DE STREROIDES

Country Status (20)

Country	Link
JP (1)	JPS50101358A (fr)
AR (1)	AR209758A1 (fr)
BE (1)	BE824405A (fr)
CA (1)	CA1050966A (fr)
CH (1)	CH606116A5 (fr)
CS (1)	CS182829B2 (fr)
DD (1)	DD117449A5 (fr)
DE (1)	DE2501041A1 (fr)
DK (1)	DK9075A (fr)
ES (1)	ES433814A1 (fr)
FI (1)	FI750090A (fr)
FR (2)	FR2257299B1 (fr)
GB (1)	GB1498132A (fr)
IE (1)	IE42427B1 (fr)
IL (1)	IL46436A (fr)
NL (1)	NL7500458A (fr)
NO (1)	NO750119L (fr)
SE (1)	SE7500430L (fr)
SU (1)	SU581874A3 (fr)
ZA (1)	ZA75298B (fr)

1975
- 1975-01-13 DE DE19752501041 patent/DE2501041A1/de not_active Withdrawn
- 1975-01-15 IE IE78/75A patent/IE42427B1/en unknown
- 1975-01-15 SE SE7500430A patent/SE7500430L/xx unknown
- 1975-01-15 ZA ZA00750298A patent/ZA75298B/xx unknown
- 1975-01-15 AR AR257302A patent/AR209758A1/es active
- 1975-01-15 BE BE152397A patent/BE824405A/fr unknown
- 1975-01-15 NO NO750119A patent/NO750119L/no unknown
- 1975-01-15 FR FR7501118A patent/FR2257299B1/fr not_active Expired
- 1975-01-15 JP JP50006984A patent/JPS50101358A/ja active Pending
- 1975-01-15 CH CH42775A patent/CH606116A5/xx not_active IP Right Cessation
- 1975-01-15 FI FI750090A patent/FI750090A/fi not_active Application Discontinuation
- 1975-01-15 GB GB1776/75A patent/GB1498132A/en not_active Expired
- 1975-01-15 DK DK9075*BA patent/DK9075A/da unknown
- 1975-01-15 CA CA217,981A patent/CA1050966A/fr not_active Expired
- 1975-01-15 CS CS7500000281A patent/CS182829B2/cs unknown
- 1975-01-15 DD DD183650A patent/DD117449A5/xx unknown
- 1975-01-15 ES ES433814A patent/ES433814A1/es not_active Expired
- 1975-01-15 IL IL46436A patent/IL46436A/xx unknown
- 1975-01-15 NL NL7500458A patent/NL7500458A/xx not_active Application Discontinuation
- 1975-01-16 SU SU7502099683A patent/SU581874A3/ru active
- 1975-09-15 FR FR7528266A patent/FR2279760A1/fr active Granted

Also Published As

Publication number	Publication date
FR2257299A1 (fr)	1975-08-08
NL7500458A (nl)	1975-07-18
SU581874A3 (ru)	1977-11-25
IL46436A0 (en)	1975-06-25
DK9075A (fr)	1975-09-15
FR2279760A1 (fr)	1976-02-20
AR209758A1 (es)	1977-05-31
CS182829B2 (en)	1978-05-31
GB1498132A (en)	1978-01-18
NO750119L (fr)	1975-07-17
CH606116A5 (fr)	1978-10-13
FR2279760B1 (fr)	1978-09-22
SE7500430L (fr)	1975-07-17
IL46436A (en)	1979-05-31
AU7731075A (en)	1976-07-15
IE42427B1 (en)	1980-08-13
DE2501041A1 (de)	1975-07-17
IE42427L (en)	1975-07-16
ES433814A1 (es)	1977-02-16
FI750090A (fr)	1975-07-17
ZA75298B (en)	1976-01-28
FR2257299B1 (fr)	1978-08-04
DD117449A5 (fr)	1976-01-12
BE824405A (fr)	1975-07-15
JPS50101358A (fr)	1975-08-11

Publication	Publication Date	Title
US5929262A (en)	1999-07-27	Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
US4613463A (en)	1986-09-23	Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid
US3971772A (en)	1976-07-27	Steroidal[16α,17-b]1,4-dioxanes and Steroidal[16α,17-b]1,4-dioxins
US3944584A (en)	1976-03-16	Steroidal (16α,17-d)cyclohexenes
CA1050966A (fr)	1979-03-20	(16.alpha.,17-B) 1,4 DIOXANES DE STREROIDES
CA1083138A (fr)	1980-08-05	16.alpha.,17D ISOXAZOLIDINES STEROIDES
CA1055483A (fr)	1979-05-29	DERIVES STEROIDIQUES DE TYPE 9,11.beta.-DIHALO (16A, 17B) 1,4-DIOXANE
HU217632B (hu)	2000-03-28	17,20-Epoxi-pregnán-származékok és előállításuk
US3287377A (en)	1966-11-22	19-oxygenated steroids from 5alpha-halogen-6beta:19-oxido-steroids
EP0201042B1 (fr)	1991-08-28	3-Alpha, 5-cyclo-22,23-dihydroxy-5 alpha-stéroides
US3945997A (en)	1976-03-23	Steroidal bicyclic dioxanes
CA1255296A (fr)	1989-06-06	[16,17-a] cyclopentanopregenes
US4046760A (en)	1977-09-06	Process for preparing 1-α-hydroxy cholesterol derivatives
US4843157A (en)	1989-06-27	13alpha-alkylgonan-delta 9(11)-5,10-epoxides
US3639392A (en)	1972-02-01	Cardioactive oxido-bufatrienolides
US2744108A (en)	1956-05-01	3-ethylene mercaptoles of 11-oxygenated derivatives of 17, 21-dihydroxy-4-pregnene-3, 20-diones
US4031080A (en)	1977-06-21	16-Alpha-methyl-17 alpha-bromo-1,4-pregnadiene-21-ol-3,20-dione-derivatives
CA1113925A (fr)	1981-12-08	D-homo oxasteroides
IE861233L (en)	1986-11-10	17-alpha-ethynyl steroid
US4207235A (en)	1980-06-10	Selective epoxidation of steroidal bromohydrins
US3684674A (en)	1972-08-15	Process for preparing 18-cyano-pregnane compounds
CA1047507A (fr)	1979-01-30	4,5-seco-steroides
US5128464A (en)	1992-07-07	6,6-ethylenedioxy-22R-hydroxy-2R,3S-isopropylidendioxy-5α-cholst-23-yne
US3976637A (en)	1976-08-24	3,20-Diketopregnenes having an 11β-acetal group
US3639394A (en)	1972-02-01	Process for the manufacture of 14beta-hydroxy-3-oxo-5alpha-card-20(22)-enolides