CA1032928A - Process for preparing 3-alkyl-3-cephem-4-carboxylic acids and intermediates thereof - Google Patents

Process for preparing 3-alkyl-3-cephem-4-carboxylic acids and intermediates thereof

Info

Publication number
CA1032928A
CA1032928A CA183,329A CA183329A CA1032928A CA 1032928 A CA1032928 A CA 1032928A CA 183329 A CA183329 A CA 183329A CA 1032928 A CA1032928 A CA 1032928A
Authority
CA
Canada
Prior art keywords
cephem
intermediates
alkyl
preparing
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA183,329A
Other languages
English (en)
French (fr)
Other versions
CA183329S (en
Inventor
Masashi Hashimoto
Teruo Oku
Tsutomu Teraji
Takashi Kamiya
Osamu Nakaguti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47105558A external-priority patent/JPS5757473B2/ja
Priority claimed from JP11911472A external-priority patent/JPS5541239B2/ja
Priority claimed from JP12557472A external-priority patent/JPS5547037B2/ja
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1032928A publication Critical patent/CA1032928A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/08—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA183,329A 1972-10-20 1973-10-15 Process for preparing 3-alkyl-3-cephem-4-carboxylic acids and intermediates thereof Expired CA1032928A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP47105558A JPS5757473B2 (de) 1972-10-20 1972-10-20
JP11911472A JPS5541239B2 (de) 1972-11-27 1972-11-27
JP12557472A JPS5547037B2 (de) 1972-12-13 1972-12-13

Publications (1)

Publication Number Publication Date
CA1032928A true CA1032928A (en) 1978-06-13

Family

ID=27310524

Family Applications (1)

Application Number Title Priority Date Filing Date
CA183,329A Expired CA1032928A (en) 1972-10-20 1973-10-15 Process for preparing 3-alkyl-3-cephem-4-carboxylic acids and intermediates thereof

Country Status (7)

Country Link
US (1) US4091210A (de)
CA (1) CA1032928A (de)
CH (1) CH590876A5 (de)
DE (1) DE2352198A1 (de)
FR (2) FR2208910B1 (de)
GB (1) GB1451459A (de)
NL (1) NL7314423A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267340A (en) * 1971-06-24 1981-05-12 Fujisawa Pharmaceutical Co., Ltd. Disulfide substituted oxazetidine derivatives
GB1472866A (en) * 1974-06-12 1977-05-11 Farmaceutici Italia Cephalosporins and intermediates therefor
US4159266A (en) * 1974-12-24 1979-06-26 Eli Lilly And Company Method of preparation of 3-methylenecephams
JPS5214789A (en) * 1975-07-22 1977-02-03 Shionogi & Co Ltd Process for preparing 3-substiuted cephem compounds by ring closure
US4482491A (en) * 1981-05-01 1984-11-13 Otsuka Kagaku Yakuhin Kabushiki Kaisha Thiazolinoazetidinone derivatives and process for the preparation of the same
DE3265390D1 (en) * 1981-05-19 1985-09-19 Ciba Geigy Ag Process for the preparation of 4-thio-azetidinone compounds
IN173329B (de) * 1989-11-06 1994-04-02 Ranbaxy Lab Ltd
FR3136425B1 (fr) 2022-06-09 2024-04-26 Psa Automobiles Sa Support latéral de panneau de plancher de coffre.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275626A (en) * 1962-07-31 1966-09-27 Lilly Co Eli Penicillin conversion via sulfoxide
DK136480B (da) * 1969-03-11 1977-10-17 Glaxo Lab Ltd Fremgangsmåde til fremstilling af 7beta-acylamido-3-metylceph-3-em-4-karboxylsyreestere ved omlejring af en 6beta-acylamidopenicillansyre-1-oxydester.
GB1312233A (en) * 1969-12-05 1973-04-04 Glaxo Lab Ltd Cephalosporin compounds
US4024152A (en) * 1975-09-19 1977-05-17 Eli Lilly And Company 4-Dithio-3-imido-azetidin-2-ones

Also Published As

Publication number Publication date
US4091210A (en) 1978-05-23
FR2208910A1 (de) 1974-06-28
FR2205522B1 (de) 1978-06-30
CH590876A5 (de) 1977-08-31
FR2208910B1 (de) 1978-09-15
NL7314423A (de) 1974-04-23
DE2352198A1 (de) 1974-05-02
GB1451459A (en) 1976-10-06
FR2205522A1 (de) 1974-05-31

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