CA1032533A - Procede de fabrication des composes de la cephalosporine - Google Patents

Procede de fabrication des composes de la cephalosporine

Info

Publication number
CA1032533A
CA1032533A CA205,823A CA205823A CA1032533A CA 1032533 A CA1032533 A CA 1032533A CA 205823 A CA205823 A CA 205823A CA 1032533 A CA1032533 A CA 1032533A
Authority
CA
Canada
Prior art keywords
production
cephalosporin compounds
cephalosporin
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA205,823A
Other languages
English (en)
Other versions
CA205823S (en
Inventor
William H. Koster
William A. Slusarchyk
Joseph E. Dolfini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of CA1032533A publication Critical patent/CA1032533A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA205,823A 1973-09-07 1974-07-29 Procede de fabrication des composes de la cephalosporine Expired CA1032533A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39520173A 1973-09-07 1973-09-07

Publications (1)

Publication Number Publication Date
CA1032533A true CA1032533A (fr) 1978-06-06

Family

ID=23562072

Family Applications (1)

Application Number Title Priority Date Filing Date
CA205,823A Expired CA1032533A (fr) 1973-09-07 1974-07-29 Procede de fabrication des composes de la cephalosporine

Country Status (14)

Country Link
US (1) US4071682A (fr)
JP (1) JPS5053391A (fr)
AR (1) AR209595A1 (fr)
BE (1) BE819635A (fr)
CA (1) CA1032533A (fr)
DE (1) DE2440142A1 (fr)
DK (1) DK470474A (fr)
FR (1) FR2256170B1 (fr)
GB (1) GB1481710A (fr)
HU (1) HU168867B (fr)
IE (1) IE40926B1 (fr)
NL (1) NL7411784A (fr)
NO (1) NO743221L (fr)
SE (1) SE7411311L (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1366682A (en) * 1971-04-30 1974-09-11 Merck & Co Inc Process to prepare antibiotic intermediates
US4169946A (en) * 1976-12-08 1979-10-02 E. R. Squibb & Sons, Inc. Reactions of thiooxime cephalosporin and penicillin derivatives
US4206305A (en) * 1979-03-12 1980-06-03 Richardson-Merrell Inc. 7-(1,3-Dithiolan-2-imino)cephalosporanic acid derivatives
US4208516A (en) * 1979-03-12 1980-06-17 Richardson-Merrell Inc. 7-(1,3-Dithiolan-2-imino)-Δ2 -cephalosporanic acid derivatives
FR2496666A1 (fr) * 1980-12-22 1982-06-25 Ici Pharma Nouveaux derives de cephalosporine et composition pharmaceutique les contenant
DE69011702T2 (de) * 1989-01-06 1995-04-06 Gist Brocades Nv Derivate von Aminocarboxylsäure.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1366682A (en) * 1971-04-30 1974-09-11 Merck & Co Inc Process to prepare antibiotic intermediates
US3840533A (en) * 1971-08-24 1974-10-08 Squibb & Sons Inc 7-substituted cephalosporanic acid and derivatives thereof
US3954744A (en) * 1972-06-07 1976-05-04 E. R. Squibb & Sons, Inc. 7-Substituted cephalosporanic acid and derivatives thereof
US3954731A (en) * 1972-07-03 1976-05-04 Eli Lilly And Company Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids
US3947413A (en) * 1972-11-13 1976-03-30 Merck & Co., Inc. 3-α-Substituted cephalosporins

Also Published As

Publication number Publication date
AU7192074A (en) 1976-02-05
FR2256170A1 (fr) 1975-07-25
GB1481710A (en) 1977-08-03
AR209595A1 (es) 1977-05-13
SE7411311L (fr) 1975-03-10
HU168867B (fr) 1976-07-28
FR2256170B1 (fr) 1980-05-23
JPS5053391A (fr) 1975-05-12
IE40926L (en) 1975-03-07
BE819635A (fr) 1975-03-06
DE2440142A1 (de) 1975-03-13
NO743221L (fr) 1975-04-01
DK470474A (fr) 1975-05-05
US4071682A (en) 1978-01-31
IE40926B1 (en) 1979-09-12
NL7411784A (nl) 1975-03-11

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