CA1030522A - D-homo ceto-20 pregnanes - Google Patents

D-homo ceto-20 pregnanes

Info

Publication number
CA1030522A
CA1030522A CA215,097A CA215097A CA1030522A CA 1030522 A CA1030522 A CA 1030522A CA 215097 A CA215097 A CA 215097A CA 1030522 A CA1030522 A CA 1030522A
Authority
CA
Canada
Prior art keywords
pregnanes
keto
homo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA215,097A
Other languages
English (en)
Other versions
CA215097S (en
Inventor
Klaus Kieslich
Karl Petzoldt
Rudolf Wiechert
Reinhard Horowski
Gert Paschelke
Dieter Palenschat
Ulrich Kerb
Helmut Wachtel
Wolfgang Kehr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2360443A external-priority patent/DE2360443A1/de
Priority claimed from DE19742445161 external-priority patent/DE2445161A1/de
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1030522A publication Critical patent/CA1030522A/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
CA215,097A 1973-11-30 1974-12-02 D-homo ceto-20 pregnanes Expired CA1030522A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2360443A DE2360443A1 (de) 1973-11-30 1973-11-30 D-homo-20-ketopregnane
DE19742445161 DE2445161A1 (de) 1974-09-19 1974-09-19 D-homo-20-ketopregnane ii

Publications (1)

Publication Number Publication Date
CA1030522A true CA1030522A (fr) 1978-05-02

Family

ID=25766200

Family Applications (1)

Application Number Title Priority Date Filing Date
CA215,097A Expired CA1030522A (fr) 1973-11-30 1974-12-02 D-homo ceto-20 pregnanes

Country Status (14)

Country Link
US (1) US4045574A (fr)
JP (1) JPS5084561A (fr)
AT (1) AT347611B (fr)
CA (1) CA1030522A (fr)
CH (1) CH618183A5 (fr)
DD (1) DD115659A5 (fr)
DK (1) DK134348C (fr)
ES (1) ES432106A1 (fr)
FR (1) FR2253512B1 (fr)
GB (1) GB1494097A (fr)
IE (1) IE40423B1 (fr)
IL (1) IL46153A (fr)
NL (1) NL7415577A (fr)
SE (1) SE408426B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879316A (en) * 1987-02-26 1989-11-07 The University Of Tennessee Research Corporation Interpenetrating polymer network ion exchange membranes and method for preparing same
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents
DE60308388T2 (de) * 2002-08-16 2007-09-20 Pharmacia & Upjohn Co. Llc, Kalamazoo 5-Androsten-3beta-ol-Steroide und Verfahren für ihre Herstellung
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
SI2986623T1 (sl) 2013-04-17 2019-03-29 Sage Therapeutics, Inc. 19-NOR C3,3-disubstituirani C21-N-pirazolil steroidi in metode njhove uporabe
WO2014169836A1 (fr) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor-stéroïdes neuroactifs et procédés d'utilisation de ceux-ci
CN112110976B (zh) 2013-04-17 2023-08-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
WO2014169831A1 (fr) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor-hétéroaryl-stéroïdes c21-c-liés c3,3-disubstitués et procédés d'utilisation de ceux-ci
DK3021852T3 (da) 2013-07-19 2021-03-15 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser deraf
WO2015027227A1 (fr) 2013-08-23 2015-02-26 Sage Therapeutics, Inc. Stéroïdes neuroactifs, compositions et utilisations
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
SG10202009859YA (en) 2014-10-16 2020-11-27 Sage Therapeutics Inc Compositions and methods for treating cns disorders
WO2016061537A1 (fr) 2014-10-16 2016-04-21 Sage Therapeutics, Inc. Compositions et méthodes pour traiter des troubles du snc
WO2016082789A1 (fr) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions et procédés pour traiter des troubles du snc
EP3250210B1 (fr) 2015-01-26 2020-12-02 Sage Therapeutics, Inc. Compositions et méthodes pour le traitement des troubles du snc
EP4155314A1 (fr) 2015-02-20 2023-03-29 Sage Therapeutics, Inc. Stéroïdes neuroactifs, compositions et leurs utilisations
EP3481844B1 (fr) 2016-07-11 2024-04-17 Sage Therapeutics, Inc. Stéroïdes neuroactifs substitués en c12 et méthodes d'utilisation associées
IL264129B2 (en) 2016-07-11 2024-05-01 Sage Therapeutics Inc C20, C17 and C21 converted neuroactive steroids and methods of using them
KR20200104349A (ko) * 2017-12-22 2020-09-03 세이지 테라퓨틱스, 인크. Cns 장애의 치료를 위한 조성물 및 방법
KR20210112318A (ko) 2018-12-05 2021-09-14 세이지 테라퓨틱스, 인크. 신경활성 스테로이드 및 이의 사용 방법
CR20210629A (es) 2019-05-31 2022-03-22 Sage Therapeutics Inc Esteroides neuroactivos y composiciones de estos
WO2020264512A1 (fr) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Composés pour le traitement de troubles du système nerveux central
CA3144701A1 (fr) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Compositions et methodes de traitement de troubles du systeme nerveux central

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof
US3686223A (en) * 1968-12-26 1972-08-22 Sterling Drug Inc D-homoestratrienes
US3833621A (en) * 1972-03-20 1974-09-03 Richardson Merrell Inc 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same

Also Published As

Publication number Publication date
DD115659A5 (fr) 1975-10-12
CH618183A5 (fr) 1980-07-15
FR2253512A1 (fr) 1975-07-04
SE7414960L (fr) 1975-06-02
US4045574A (en) 1977-08-30
ES432106A1 (es) 1976-11-01
IE40423L (en) 1975-05-30
GB1494097A (en) 1977-12-07
AU7586774A (en) 1976-06-03
IL46153A0 (en) 1975-02-10
DK134348B (da) 1976-10-25
IE40423B1 (en) 1979-05-23
IL46153A (en) 1979-01-31
NL7415577A (nl) 1975-06-03
AT347611B (de) 1979-01-10
JPS5084561A (fr) 1975-07-08
SE408426B (sv) 1979-06-11
DK134348C (da) 1977-03-21
ATA950774A (de) 1978-05-15
DK604174A (fr) 1975-07-28
FR2253512B1 (fr) 1978-02-03

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