CA1027117A - Homogeneous catalytic reduction of 6-methylenetetracyclines - Google Patents

Homogeneous catalytic reduction of 6-methylenetetracyclines

Info

Publication number
CA1027117A
CA1027117A CA191,157A CA191157A CA1027117A CA 1027117 A CA1027117 A CA 1027117A CA 191157 A CA191157 A CA 191157A CA 1027117 A CA1027117 A CA 1027117A
Authority
CA
Canada
Prior art keywords
methylenetetracyclines
catalytic reduction
homogeneous catalytic
homogeneous
reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA191,157A
Other languages
French (fr)
Other versions
CA191157S (en
Inventor
Hermann Faubl
Thomas M. Brennan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27406609&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA1027117(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1027117A publication Critical patent/CA1027117A/en
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82Metals of the platinum group
    • B01J2531/822Rhodium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CA191,157A 1973-02-01 1974-01-29 Homogeneous catalytic reduction of 6-methylenetetracyclines Expired CA1027117A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32851473A 1973-02-01 1973-02-01
US36806073A 1973-06-08 1973-06-08
US42827873A 1973-12-26 1973-12-26

Publications (1)

Publication Number Publication Date
CA1027117A true CA1027117A (en) 1978-02-28

Family

ID=27406609

Family Applications (1)

Application Number Title Priority Date Filing Date
CA191,157A Expired CA1027117A (en) 1973-02-01 1974-01-29 Homogeneous catalytic reduction of 6-methylenetetracyclines

Country Status (18)

Country Link
JP (1) JPS5912111B2 (en)
AR (1) AR210453A1 (en)
CA (1) CA1027117A (en)
CH (1) CH589605A5 (en)
DD (1) DD110855A5 (en)
DE (1) DE2403714A1 (en)
ES (1) ES422758A1 (en)
FI (1) FI58492C (en)
FR (1) FR2216268A1 (en)
IE (1) IE38797B1 (en)
IL (1) IL44084A (en)
IN (1) IN138662B (en)
LU (1) LU69288A1 (en)
NL (1) NL166921B (en)
NO (2) NO151585C (en)
PH (1) PH14446A (en)
SE (1) SE435619C (en)
YU (1) YU39915B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR208347A1 (en) * 1974-12-19 1976-12-20 Pfizer IMPROVEMENT IN THE PRODUCTION OF ALPHA-6-DEOXYTETRACYCLINES
YU41093B (en) * 1978-04-12 1986-12-31 Pliva Pharm & Chem Works Process for preparing 6-deoxy-5hydroxy-tetracycline
PT76061A (en) * 1982-12-30 1983-01-01 Stable homogeneous hydrogenation rhodium catalyst - useful in high yield prodn. of doxycycline by stereospecific hydrogenation
USRE32535E (en) * 1982-01-19 1987-10-27 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
US4550096A (en) * 1982-01-19 1985-10-29 Plurichemie Anstalt Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same
DK386784A (en) * 1983-08-17 1985-02-18 Hovione Int Ltd PROCEDURE FOR PREPARING ALFA-6-DESOXY-TETRACYCLINES
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
DE68900339D1 (en) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd METHOD FOR PRODUCING ALPHA-6-DEOXYTETRACYCLINES.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639439A (en) * 1964-12-10 1972-02-01 Shell Oil Co Rhodium (i) halide complexes
US3489786A (en) * 1964-12-10 1970-01-13 Shell Oil Co Hydrogenation process
GB1121643A (en) * 1966-02-07 1968-07-31 Ici Ltd Hydrogenation process
GB1418137A (en) * 1972-02-24 1975-12-17 Ankerfarm Spa Process for the preparation of alpha-6-deoxytetracyclines
AR208347A1 (en) * 1974-12-19 1976-12-20 Pfizer IMPROVEMENT IN THE PRODUCTION OF ALPHA-6-DEOXYTETRACYCLINES

Also Published As

Publication number Publication date
NO843825L (en) 1974-08-02
SE7400879L (en) 1974-09-12
AU6490674A (en) 1975-07-31
PH14446A (en) 1981-07-22
SE435619B (en) 1984-10-08
JPS49102662A (en) 1974-09-27
DD110855A5 (en) 1975-01-12
IE38797B1 (en) 1978-06-07
IN138662B (en) 1976-03-06
NO740320L (en) 1974-08-02
IL44084A (en) 1977-10-31
FI58492B (en) 1980-10-31
NO151585C (en) 1985-05-08
NO153806B (en) 1986-02-17
YU39915B (en) 1985-06-30
SE435619C (en) 1985-11-18
YU25374A (en) 1982-02-28
FR2216268A1 (en) 1974-08-30
CH589605A5 (en) 1977-07-15
NO153806C (en) 1986-05-28
IE38797L (en) 1974-08-01
DE2403714A1 (en) 1974-08-22
ES422758A1 (en) 1976-08-01
IL44084A0 (en) 1974-05-16
AR210453A1 (en) 1977-08-15
FR2216268B1 (en) 1978-01-06
JPS5912111B2 (en) 1984-03-21
DE2403714C2 (en) 1987-04-09
NO151585B (en) 1985-01-21
NL166921B (en) 1981-05-15
FI58492C (en) 1986-09-05
LU69288A1 (en) 1974-09-25
NL7401340A (en) 1974-08-05

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