CA1009657A - Method of preparation of 5-fluorouracil - Google Patents

Method of preparation of 5-fluorouracil

Info

Publication number
CA1009657A
CA1009657A CA124,296A CA124296A CA1009657A CA 1009657 A CA1009657 A CA 1009657A CA 124296 A CA124296 A CA 124296A CA 1009657 A CA1009657 A CA 1009657A
Authority
CA
Canada
Prior art keywords
fluorouracil
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA124,296A
Other versions
CA124296S (en
Inventor
Robert H. Hesse
Derek H.R. Barton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Institute for Medicine and Chemistry Inc
Original Assignee
Research Institute for Medicine and Chemistry Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Institute for Medicine and Chemistry Inc filed Critical Research Institute for Medicine and Chemistry Inc
Application granted granted Critical
Publication of CA1009657A publication Critical patent/CA1009657A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA124,296A 1970-10-05 1971-10-04 Method of preparation of 5-fluorouracil Expired CA1009657A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7823570A 1970-10-05 1970-10-05

Publications (1)

Publication Number Publication Date
CA1009657A true CA1009657A (en) 1977-05-03

Family

ID=22142782

Family Applications (1)

Application Number Title Priority Date Filing Date
CA124,296A Expired CA1009657A (en) 1970-10-05 1971-10-04 Method of preparation of 5-fluorouracil

Country Status (16)

Country Link
JP (4) JPS5432790B1 (en)
AR (1) AR199762A1 (en)
AU (1) AU454408B2 (en)
BE (1) BE773446A (en)
CA (1) CA1009657A (en)
CH (1) CH567002A5 (en)
DE (1) DE2149504A1 (en)
DK (1) DK128496B (en)
FR (1) FR2110952A5 (en)
GB (1) GB1362839A (en)
HK (1) HK15678A (en)
IL (1) IL37855A (en)
NL (1) NL7113583A (en)
NO (1) NO135985C (en)
SE (1) SE408418B (en)
ZA (1) ZA716637B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2401619C2 (en) * 1974-01-14 1986-04-03 Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri Fungistically active uracil derivatives and processes for their preparation
JPS52133994A (en) * 1976-04-29 1977-11-09 Daikin Ind Ltd Method of fluorination
JPS5640813A (en) * 1979-09-10 1981-04-17 Minolta Camera Co Ltd Electric power unit for flash emitting device
JPS58140098A (en) * 1982-01-27 1983-08-19 Daikin Ind Ltd Uridine derivative and its preparation
JPS59116934U (en) * 1983-01-27 1984-08-07 オリンパス光学工業株式会社 External power supply for strobe
JPS60190769A (en) * 1984-03-09 1985-09-28 Sagami Chem Res Center Production of 5-fluorouracil
JPH055677Y2 (en) * 1985-05-22 1993-02-15

Also Published As

Publication number Publication date
AU3418171A (en) 1973-04-12
JPS58421B2 (en) 1983-01-06
NL7113583A (en) 1972-04-07
AU454408B2 (en) 1974-10-31
NO135985B (en) 1977-03-28
FR2110952A5 (en) 1972-06-02
SE408418B (en) 1979-06-11
DK128496B (en) 1974-05-13
JPS5516583B2 (en) 1980-05-02
ZA716637B (en) 1972-12-27
GB1362839A (en) 1974-08-07
JPS53147081A (en) 1978-12-21
JPS53147080A (en) 1978-12-21
IL37855A0 (en) 1971-12-29
HK15678A (en) 1978-03-31
AR199762A1 (en) 1974-09-30
IL37855A (en) 1974-12-31
BE773446A (en) 1972-04-04
JPS5432790B1 (en) 1979-10-16
JPS53147082A (en) 1978-12-21
CH567002A5 (en) 1975-09-30
NO135985C (en) 1977-07-06
DE2149504A1 (en) 1972-07-06

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