BRPI1014123A2 - produção de isopreno melhorada usando o caminho dxp e mva. - Google Patents
produção de isopreno melhorada usando o caminho dxp e mva.Info
- Publication number
- BRPI1014123A2 BRPI1014123A2 BRPI1014123A BRPI1014123A BRPI1014123A2 BR PI1014123 A2 BRPI1014123 A2 BR PI1014123A2 BR PI1014123 A BRPI1014123 A BR PI1014123A BR PI1014123 A BRPI1014123 A BR PI1014123A BR PI1014123 A2 BRPI1014123 A2 BR PI1014123A2
- Authority
- BR
- Brazil
- Prior art keywords
- path
- dxp
- mva
- isoprene production
- improved isoprene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
produção de isopreno melhorada usando o caminho dxp e mva a presente invenção refere-se a métodos de produção de isopreno a partir de células cultivadas, com o uso de vários componentes do caminho dxp e caminho mva, ou componentes associados ao caminho dxp e ao caminho mva, polipeptídeos redox de interação por agrupamento ferro-enxofre e isopreno sintase. a invenção também fornece composições que incluem estas células cultivadas.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18793009P | 2009-06-17 | 2009-06-17 | |
US18794109P | 2009-06-17 | 2009-06-17 | |
US31498510P | 2010-03-17 | 2010-03-17 | |
US31497910P | 2010-03-17 | 2010-03-17 | |
PCT/US2010/038904 WO2010148150A1 (en) | 2009-06-17 | 2010-06-16 | Improved isoprene production using the dxp and mva pathway |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1014123A2 true BRPI1014123A2 (pt) | 2019-07-02 |
Family
ID=43356749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1014123A BRPI1014123A2 (pt) | 2009-06-17 | 2010-06-16 | produção de isopreno melhorada usando o caminho dxp e mva. |
Country Status (10)
Country | Link |
---|---|
US (2) | US8507235B2 (pt) |
EP (1) | EP2443244A4 (pt) |
CN (1) | CN102753697A (pt) |
AR (1) | AR077115A1 (pt) |
BR (1) | BRPI1014123A2 (pt) |
CA (1) | CA2765805A1 (pt) |
MY (1) | MY158160A (pt) |
SG (2) | SG176936A1 (pt) |
TW (2) | TWI427149B (pt) |
WO (1) | WO2010148150A1 (pt) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
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ZA201007564B (en) | 2008-04-23 | 2012-01-25 | Goodyear Tire & Rubber | Isoprene synthase variants for improved microbial production of isoprene |
WO2010031062A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using the archaeal lower mevalonate pathway |
US8470581B2 (en) * | 2008-09-15 | 2013-06-25 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
US20100184178A1 (en) * | 2008-09-15 | 2010-07-22 | Zachary Quinn Beck | Increased isoprene production using mevalonate kinase and isoprene synthase |
US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
US8518686B2 (en) | 2009-04-23 | 2013-08-27 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
TWI427149B (zh) * | 2009-06-17 | 2014-02-21 | Danisco Us Inc | 使用dxp及mva途徑之改良之異戊二烯製造 |
US20110039323A1 (en) * | 2009-08-14 | 2011-02-17 | Eric Lawrence Singsaas | Isoprene Production |
AU2010331946A1 (en) * | 2009-12-18 | 2012-06-28 | Danisco Us Inc. | Purification of isoprene from renewable resources |
JP5855576B2 (ja) * | 2009-12-22 | 2016-02-09 | ダニスコ・ユーエス・インク | イソプレンガスの生成量を増大させるための膜バイオリアクター |
WO2011160081A1 (en) | 2010-06-17 | 2011-12-22 | Danisco Us Inc. | Fuel compositions comprising isoprene derivatives |
EP2601300A1 (en) | 2010-08-06 | 2013-06-12 | Danisco US Inc. | Production of isoprene under neutral ph conditions |
SG190043A1 (en) | 2010-10-27 | 2013-06-28 | Danisco Us Inc | Isoprene synthase variants for improved production of isoprene |
WO2012088462A1 (en) | 2010-12-22 | 2012-06-28 | Danisco Us Inc. | Compositions and methods for improved isoprene production using two types of ispg enzymes |
JP2014502844A (ja) | 2010-12-22 | 2014-02-06 | ダニスコ・ユーエス・インク | 組み換え細胞による五炭糖の生物学的生産 |
WO2012135591A2 (en) * | 2011-03-30 | 2012-10-04 | Amyris, Inc. | Microbial isoprenoid production using a heterologous dxp pathway |
EP2702139A1 (en) | 2011-04-29 | 2014-03-05 | Danisco US Inc. | Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, hmg-coa synthase and hmg-coa reductase enzymatic activities |
ES2699747T3 (es) | 2011-04-29 | 2019-02-12 | Danisco Us Inc | Microorganismos recombinantes para la producción potenciada de mevalonato, isopreno e isoprenoides |
EP2739658A1 (en) | 2011-08-04 | 2014-06-11 | Danisco US Inc. | Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-coa synthase |
US8951764B2 (en) | 2011-08-05 | 2015-02-10 | Danisco Us Inc. | Production of isoprenoids under neutral pH conditions |
PL222067B1 (pl) * | 2011-08-11 | 2016-06-30 | Inst Biotechnologii I Antybiotyków | Kaseta ekspresyjna, zastosowanie kasety ekspresyjnej, wektor ekspresyjny, komórka prokariotycznego gospodarza zawierająca wektor ekspresyjny, szczep bakteryjny oraz sposób wytwarzania polipeptydu |
DK3339426T3 (da) | 2011-10-07 | 2022-09-12 | Danisco Us Inc | Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer og isopren |
BR112014010053A8 (pt) | 2011-10-27 | 2017-06-20 | Danisco Us Inc | variantes de isopreno sintase com solubilidade aprimorada para produção de isopreno |
WO2013096917A1 (en) | 2011-12-23 | 2013-06-27 | Danisco Us Inc. | Production of isoprene under reduced oxygen inlet levels |
JP2015510392A (ja) | 2011-12-23 | 2015-04-09 | ダニスコ・ユーエス・インク | 低減したispa活性を有する宿主細胞を用いるイソプレン産生増強法 |
WO2013096863A1 (en) * | 2011-12-23 | 2013-06-27 | The Regents Of The University Of California | Constructs and methods for improved isoprene biosynthesis |
US9315831B2 (en) | 2012-03-30 | 2016-04-19 | Danisco Us Inc. | Direct starch to fermentable sugar as feedstock for the production of isoprene, isoprenoid precursor molecules, and/or isoprenoids |
US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
US8895277B2 (en) | 2012-05-02 | 2014-11-25 | Danisco Us Inc. | Legume isoprene synthase for production of isoprene |
US20130323820A1 (en) * | 2012-06-01 | 2013-12-05 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
WO2013181647A2 (en) | 2012-06-01 | 2013-12-05 | Danisco Us Inc. | Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms |
EP2898053B1 (en) | 2012-09-20 | 2021-08-25 | Danisco US Inc. | Microtiter plates for controlled release of culture components to cell cultures |
WO2014066892A1 (en) * | 2012-10-26 | 2014-05-01 | Coelho Pedro S | De novo metabolic pathways for isoprene biosynthesis |
EP2935364A2 (en) | 2012-12-21 | 2015-10-28 | Danisco US Inc. | Production of isoprene, isoprenoid, and isoprenoid precursors using an alternative lower mevalonate pathway |
CA2901588A1 (en) * | 2013-03-07 | 2014-09-12 | Calysta, Inc. | Compositions and methods for biological production of isoprene |
US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
WO2014169144A2 (en) | 2013-04-10 | 2014-10-16 | Danisco Us Inc. | Phosphoketolases foe improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precurosors, and isoprenoids |
CA2915980A1 (en) | 2013-06-21 | 2014-12-24 | Danisco Us Inc. | Compositions and methods for clostridial transformation |
CN103602626B (zh) * | 2013-10-12 | 2016-02-10 | 中国科学院青岛生物能源与过程研究所 | 一种以油脂为原料生产甲羟戊酸的方法及其构建的基因工程菌 |
CN103667153B (zh) * | 2013-12-19 | 2015-05-13 | 中国石油大学(华东) | 一株产聚3-羟基丁酸酯的嗜热菌 |
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WO2016015021A1 (en) | 2014-07-24 | 2016-01-28 | The Regents Of The University Of California | Oxidative starch degradation by a new family of pmos |
CA2939005C (en) | 2014-09-17 | 2020-09-08 | WCCO Belting, Inc. | Environmentally friendly rubber composition |
CN104372017B (zh) * | 2014-11-05 | 2017-06-30 | 中国科学院青岛生物能源与过程研究所 | 一种提高基因工程菌异戊二烯及其衍生物产量的方法及应用 |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
CA3051472A1 (en) | 2017-01-26 | 2018-08-02 | Manus Bio, Inc. | Metabolic engineering for microbial production of terpenoid products |
US10662442B2 (en) * | 2017-02-03 | 2020-05-26 | Manus Bio Inc. | Metabolic engineering for microbial production of terpenoid products |
CN110468091B (zh) * | 2018-05-09 | 2023-07-11 | 深圳艾格鑫科技有限公司 | 微生物及其用途 |
CN110468090B (zh) * | 2018-05-09 | 2023-07-04 | 深圳艾格鑫科技有限公司 | 微生物及其用途 |
CN108715825B (zh) * | 2018-06-01 | 2021-03-09 | 天津大学 | 基因过表达及获得的菌株、应用 |
CN109609424B (zh) * | 2018-12-26 | 2020-07-31 | 浙江医药股份有限公司 | 用于生产法尼烯的大肠杆菌 |
US20220162188A1 (en) * | 2019-01-15 | 2022-05-26 | North Carolina State University | Isoprenoids and methods of making thereof |
EP3683227A1 (en) * | 2019-01-16 | 2020-07-22 | Biosyntia ApS | Cell factories for improved production of compounds and proteins dependent on iron sulfur clusters |
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KR20120053088A (ko) * | 2006-05-26 | 2012-05-24 | 아미리스 인코퍼레이티드 | 이소프레노이드의 생산 방법 |
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CA2737236A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Systems using cell culture for production of isoprene |
US20100184178A1 (en) | 2008-09-15 | 2010-07-22 | Zachary Quinn Beck | Increased isoprene production using mevalonate kinase and isoprene synthase |
JP5793424B2 (ja) | 2008-12-30 | 2015-10-14 | ダニスコ・ユーエス・インク | イソプレンと副生成物の産出方法 |
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TWI427149B (zh) | 2009-06-17 | 2014-02-21 | Danisco Us Inc | 使用dxp及mva途徑之改良之異戊二烯製造 |
EP2477478B1 (en) | 2009-09-15 | 2016-11-30 | Sapphire Energy, Inc. | A system for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp. |
AU2010331946A1 (en) | 2009-12-18 | 2012-06-28 | Danisco Us Inc. | Purification of isoprene from renewable resources |
SG190043A1 (en) | 2010-10-27 | 2013-06-28 | Danisco Us Inc | Isoprene synthase variants for improved production of isoprene |
WO2012088462A1 (en) | 2010-12-22 | 2012-06-28 | Danisco Us Inc. | Compositions and methods for improved isoprene production using two types of ispg enzymes |
JP2014502844A (ja) | 2010-12-22 | 2014-02-06 | ダニスコ・ユーエス・インク | 組み換え細胞による五炭糖の生物学的生産 |
-
2010
- 2010-06-15 TW TW99119621A patent/TWI427149B/zh not_active IP Right Cessation
- 2010-06-15 TW TW102141532A patent/TW201412988A/zh unknown
- 2010-06-16 SG SG2011094562A patent/SG176936A1/en unknown
- 2010-06-16 WO PCT/US2010/038904 patent/WO2010148150A1/en active Application Filing
- 2010-06-16 BR BRPI1014123A patent/BRPI1014123A2/pt not_active IP Right Cessation
- 2010-06-16 SG SG10201403297UA patent/SG10201403297UA/en unknown
- 2010-06-16 EP EP10790161.3A patent/EP2443244A4/en not_active Withdrawn
- 2010-06-16 CA CA2765805A patent/CA2765805A1/en not_active Abandoned
- 2010-06-16 US US12/817,134 patent/US8507235B2/en not_active Expired - Fee Related
- 2010-06-16 AR ARP100102132 patent/AR077115A1/es unknown
- 2010-06-16 CN CN2010800359758A patent/CN102753697A/zh active Pending
- 2010-06-16 MY MYPI2011006126A patent/MY158160A/en unknown
-
2013
- 2013-07-11 US US13/940,092 patent/US20140162337A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MY158160A (en) | 2016-09-15 |
WO2010148150A1 (en) | 2010-12-23 |
AR077115A1 (es) | 2011-08-03 |
EP2443244A1 (en) | 2012-04-25 |
TWI427149B (zh) | 2014-02-21 |
TW201412988A (zh) | 2014-04-01 |
CA2765805A1 (en) | 2010-12-23 |
US8507235B2 (en) | 2013-08-13 |
SG10201403297UA (en) | 2014-10-30 |
CN102753697A (zh) | 2012-10-24 |
US20110014672A1 (en) | 2011-01-20 |
EP2443244A4 (en) | 2014-11-26 |
US20140162337A1 (en) | 2014-06-12 |
TW201111512A (en) | 2011-04-01 |
SG176936A1 (en) | 2012-02-28 |
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