BRPI0919696A2 - Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado. - Google Patents

Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.

Info

Publication number
BRPI0919696A2
BRPI0919696A2 BRPI0919696-0A BRPI0919696A BRPI0919696A2 BR PI0919696 A2 BRPI0919696 A2 BR PI0919696A2 BR PI0919696 A BRPI0919696 A BR PI0919696A BR PI0919696 A2 BRPI0919696 A2 BR PI0919696A2
Authority
BR
Brazil
Prior art keywords
isolated polynucleotide
substantially purified
recombinant microorganism
purified polypeptide
polypeptide
Prior art date
Application number
BRPI0919696-0A
Other languages
English (en)
Inventor
James C Liao
Kechun Zhang
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BRPI0919696A2 publication Critical patent/BRPI0919696A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03013—2-Isopropylmalate synthase (2.3.3.13)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0919696-0A 2008-10-18 2009-10-18 Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado. BRPI0919696A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10656208P 2008-10-18 2008-10-18
US10656108P 2008-10-18 2008-10-18
US10656308P 2008-10-18 2008-10-18
US10656408P 2008-10-18 2008-10-18
US11930808P 2008-12-02 2008-12-02
PCT/US2009/061116 WO2010045629A2 (en) 2008-10-18 2009-10-18 Production of c5-c8 alcohols using evolved enzymes and metabolically engineered microorganisms

Publications (1)

Publication Number Publication Date
BRPI0919696A2 true BRPI0919696A2 (pt) 2015-08-04

Family

ID=42107306

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919696-0A BRPI0919696A2 (pt) 2008-10-18 2009-10-18 Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.

Country Status (4)

Country Link
US (1) US8298798B2 (pt)
EP (1) EP2346991B1 (pt)
BR (1) BRPI0919696A2 (pt)
WO (1) WO2010045629A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201037078A (en) * 2009-03-11 2010-10-16 Dsm Ip Assets Bv Preparation of alpha-ketopimelic acid
EP2464736A4 (en) 2009-08-12 2013-07-31 Gevo Inc PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL
CA2830215C (en) 2011-03-14 2018-07-10 Easel Biotechnologies, Llc Microbial synthesis of aldehydes and corresponding alcohols
WO2013025277A1 (en) * 2011-08-15 2013-02-21 Exxonmobil Chemical Patents Inc. Esters and their preparation and use
JP6272767B2 (ja) 2011-11-03 2018-01-31 イーゼル・バイオテクノロジーズ・エルエルシー 微生物によるｎ−ブチルアルデヒドの生産
WO2014037912A2 (en) * 2012-09-07 2014-03-13 Cellworks Research India Pvt. Ltd Methods for production of isobutanol through nutrient stress and genetically modified microorganisms thereof
EP3080285B1 (en) * 2013-12-12 2022-07-27 Dow Global Technologies LLC Processes to prepare elongated 2-ketoacids and c6-c10 compounds therefrom via genetic modifications to microbial metabolic pathways
WO2016094604A1 (en) 2014-12-10 2016-06-16 Dow Global Technologies Llc Genetically modified phenylpyruvate decarboxylase, processes to prepare, and uses thereof
US10829756B2 (en) 2015-08-28 2020-11-10 The Regents Of The University Of California Discovery of enzymes from the alpha-keto acid decarboxylase family
CN109790554B (zh) 2016-09-30 2023-06-16 陶氏环球技术有限责任公司 通过对微生物代谢途径的基因修饰来制备伸长的2-酮酸和其c5-c10化合物的方法
WO2019067412A1 (en) 2017-09-29 2019-04-04 Dow Global Technologies Llc GENETICALLY MODIFIED ISOPROPYLMALATE ISOMERASE ENZYME COMPLEXES AND METHODS FOR PREPARING ELONGATE 2-CÉTOACIDES AND C5-C10 COMPOUNDS THEREWITH
US10808265B2 (en) 2018-09-26 2020-10-20 Nantbio, Inc. Microbes and methods for improved conversion of a feedstock
EP4034668B1 (en) 2019-09-25 2024-04-17 Ajinomoto Co., Inc. Method for producing 2-methyl-butyric acid by bacterial fermentation
JP2023518045A (ja) * 2020-03-18 2023-04-27 ランザテク，インコーポレイテッド ガス基質からの２－フェニルエタノールの発酵産生

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2201454C2 (ru) 1999-07-09 2003-03-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Мутантная альфа-изопропилмалат синтаза (ipms), днк, кодирующая мутантную ipms, способ получения штамма escherichia coli, способ получения l-лейцина
US20030167513A1 (en) * 2001-11-30 2003-09-04 Mourad George S. Selection and use of isopropylmalate synthase (IPMS) mutants desensitized in L-leucine negative feedback control
JP2005296010A (ja) * 2004-03-19 2005-10-27 Osaka Univ ２−イソプロピルリンゴ酸シンターゼ活性を有する新規耐熱性タンパク質
BRPI0807235A2 (pt) * 2007-02-09 2015-05-26 Univ California Microorganismo recombinante, e, métodos para produzir um microorganismo recombinante, e para produzir um álcool

Also Published As

Publication number Publication date
US8298798B2 (en) 2012-10-30
WO2010045629A3 (en) 2010-08-19
EP2346991A4 (en) 2013-03-27
US20110201083A1 (en) 2011-08-18
WO2010045629A2 (en) 2010-04-22
EP2346991B1 (en) 2016-12-28
EP2346991A2 (en) 2011-07-27

Similar Documents

Publication Publication Date Title
BRPI0919696A2 (pt) Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.
BRPI0820500A2 (pt) Variantes de alfa-amilase de bacillus sp. Ts-23 com propriedades alteradas
BRPI0819184A2 (pt) variantes de alfa-amilase com propriedades alteradas.
BR112012000367A2 (pt) l-asparaginase peguilada.
CL2007002227S1 (es) Botella.
DK1829959T3 (da) Rekombinant mikroorganisme
BRPI0819780A2 (pt) Plasmina modificada de forma recombinante.
BRPI0910461A2 (pt) fsh recombinante incluindo sialilação alfa 2,3 e alfa 2,6
CL2007001563S1 (es) Botella.
DK2035447T3 (da) Polypeptid
BRPI0902901A2 (pt) Novo bacteriófago e composição antibacteriana compreendendo o mesmo.
BRPI0902902A2 (pt) Novo bacteriófago e composição antibacteriana compreendendo o mesmo.
CL2007000544S1 (es) Botella.
BR112012000281A2 (pt) proteína quimérica.
CL2008001030S1 (es) Botella.
CL2007001562S1 (es) Botella.
BRPI1008941A2 (pt) Sequência polinucleotídica e polipeptídica e métodos da mesma.
CL2006003378S1 (es) Botella.
IL220359A (en) Recombinant histolyticum collagenases and a method for their production
DK2133416T3 (da) Rekombinant mikroorganisme
WO2010014922A3 (en) Protein purification tags and uses thereof
CL2007001564S1 (es) Botella.
FR2944149B1 (fr) Electrode composite.
CL2008000591S1 (es) Botella.
CL2007000545S1 (es) Botella.

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.