BRPI0905347C1 - Deformable polymeric nanocapsules in bioactive encapsulation - Google Patents

Deformable polymeric nanocapsules in bioactive encapsulation

Info

Publication number
BRPI0905347C1
BRPI0905347C1 BRPI0905347A BRPI0905347A BRPI0905347C1 BR PI0905347 C1 BRPI0905347 C1 BR PI0905347C1 BR PI0905347 A BRPI0905347 A BR PI0905347A BR PI0905347 A BRPI0905347 A BR PI0905347A BR PI0905347 C1 BRPI0905347 C1 BR PI0905347C1
Authority
BR
Brazil
Prior art keywords
encapsulation
deformable
bioactive
present
polymeric nanocapsules
Prior art date
Application number
BRPI0905347A
Other languages
Portuguese (pt)
Inventor
Eduardo Durán Caballero Nelson
Stanisçuaski Guterres Sílvia
Teixeira Camargo Zaine
Original Assignee
Univ Federal Rio Grande Sul
Univ Estadual Campinas Unicamp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Federal Rio Grande Sul, Univ Estadual Campinas Unicamp filed Critical Univ Federal Rio Grande Sul
Priority to BRPI0905347A priority Critical patent/BRPI0905347C1/en
Publication of BRPI0905347A2 publication Critical patent/BRPI0905347A2/en
Publication of BRPI0905347B1 publication Critical patent/BRPI0905347B1/en
Publication of BRPI0905347B8 publication Critical patent/BRPI0905347B8/en
Publication of BRPI0905347C1 publication Critical patent/BRPI0905347C1/en

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  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

nanocápsulas poliméricas deformáveis no encapsulamento de bioativos. a presente invenção refere-se a uma nanocápsula deformável compreendendo uma parede polimérica de poli (d,l-lactídeo) (pla) e um núcleo oleoso de palmitado de retinila que compreende um ou mais princípios ativos lipofílicos solúveis com característica de deformação, baixo índice de polidispersão, maior diâmetro comparadas com nanoesferas, alto índice de eficiência de encapsulamento, estáveis, elásticas e de baixa citotoxicidade. dessa forma, o objeto da presente invenção pode ser de grande interesse para sistemas de liberação sustentada de fármacos ou ativos cosméticos por indústrias farmacêuticas e cosméticas.deformable polymeric nanocapsules in the encapsulation of bioactives. The present invention relates to a deformable nanocapsule comprising a polymeric wall of poly(d,l-lactide) (pla) and an oil core of retinyl palmitate comprising one or more soluble lipophilic active principles with low deformation characteristic of polydispersion, larger diameter compared to nanospheres, high encapsulation efficiency, stable, elastic and low cytotoxicity. thus, the object of the present invention may be of great interest for sustained release systems for drugs or cosmetic actives by pharmaceutical and cosmetic industries.

BRPI0905347A 2009-12-15 2009-12-15 Deformable polymeric nanocapsules in bioactive encapsulation BRPI0905347C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0905347A BRPI0905347C1 (en) 2009-12-15 2009-12-15 Deformable polymeric nanocapsules in bioactive encapsulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0905347A BRPI0905347C1 (en) 2009-12-15 2009-12-15 Deformable polymeric nanocapsules in bioactive encapsulation

Publications (4)

Publication Number Publication Date
BRPI0905347A2 BRPI0905347A2 (en) 2013-07-02
BRPI0905347B1 BRPI0905347B1 (en) 2020-09-01
BRPI0905347B8 BRPI0905347B8 (en) 2020-11-17
BRPI0905347C1 true BRPI0905347C1 (en) 2021-05-25

Family

ID=48692735

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0905347A BRPI0905347C1 (en) 2009-12-15 2009-12-15 Deformable polymeric nanocapsules in bioactive encapsulation

Country Status (1)

Country Link
BR (1) BRPI0905347C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020012410A (en) 2018-05-23 2022-03-29 Unilever Ip Holdings B V Nanoemulsions and a method for making the same.

Also Published As

Publication number Publication date
BRPI0905347A2 (en) 2013-07-02
BRPI0905347B8 (en) 2020-11-17
BRPI0905347B1 (en) 2020-09-01

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B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
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B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/09/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: REF. RPI 2591 DE 01/09/2020 QUANTO TITULAR.

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/12/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF