BRPI0819703A2 - Uso de inibidores de proteína tirosina fosfatase e hormônio de crescimento humano, uso de igf1 e um inibidor de proteína tirosina fosfatase e composição de combinação farmacêutica para o tratamento de atrofia muscular e distúrbios relacionados - Google Patents
Uso de inibidores de proteína tirosina fosfatase e hormônio de crescimento humano, uso de igf1 e um inibidor de proteína tirosina fosfatase e composição de combinação farmacêutica para o tratamento de atrofia muscular e distúrbios relacionadosInfo
- Publication number
- BRPI0819703A2 BRPI0819703A2 BRPI0819703-2A BRPI0819703A BRPI0819703A2 BR PI0819703 A2 BRPI0819703 A2 BR PI0819703A2 BR PI0819703 A BRPI0819703 A BR PI0819703A BR PI0819703 A2 BRPI0819703 A2 BR PI0819703A2
- Authority
- BR
- Brazil
- Prior art keywords
- protein tyrosine
- tyrosine phosphatase
- igf1
- treatment
- growth hormone
- Prior art date
Links
- 102000002265 Human Growth Hormone Human genes 0.000 title 1
- 108010000521 Human Growth Hormone Proteins 0.000 title 1
- 239000000854 Human Growth Hormone Substances 0.000 title 1
- 101150088952 IGF1 gene Proteins 0.000 title 1
- 206010028289 Muscle atrophy Diseases 0.000 title 1
- 102000002727 Protein Tyrosine Phosphatase Human genes 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000020763 muscle atrophy Effects 0.000 title 1
- 201000000585 muscular atrophy Diseases 0.000 title 1
- 229940126731 protein tyrosine phosphatase inhibitor Drugs 0.000 title 1
- 239000003806 protein tyrosine phosphatase inhibitor Substances 0.000 title 1
- 108020000494 protein-tyrosine phosphatase Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99145707P | 2007-11-30 | 2007-11-30 | |
PCT/EP2008/066554 WO2009068689A2 (en) | 2007-11-30 | 2008-12-01 | Combination of protein tyrosine phosphatase inhibitors and human growth hormone for the treatment of muscle atrophy and related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0819703A2 true BRPI0819703A2 (pt) | 2015-06-16 |
Family
ID=40627504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0819703-2A BRPI0819703A2 (pt) | 2007-11-30 | 2008-12-01 | Uso de inibidores de proteína tirosina fosfatase e hormônio de crescimento humano, uso de igf1 e um inibidor de proteína tirosina fosfatase e composição de combinação farmacêutica para o tratamento de atrofia muscular e distúrbios relacionados |
Country Status (11)
Country | Link |
---|---|
US (1) | US20100305036A1 (pt) |
EP (1) | EP2227245A2 (pt) |
JP (1) | JP2011504918A (pt) |
KR (1) | KR20100102626A (pt) |
CN (1) | CN101883579A (pt) |
AU (1) | AU2008328683A1 (pt) |
BR (1) | BRPI0819703A2 (pt) |
CA (1) | CA2707117A1 (pt) |
EA (1) | EA201000865A1 (pt) |
MX (1) | MX2010005909A (pt) |
WO (1) | WO2009068689A2 (pt) |
Families Citing this family (81)
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US9028485B2 (en) | 2010-11-15 | 2015-05-12 | Boston Scientific Scimed, Inc. | Self-expanding cooling electrode for renal nerve ablation |
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US9060761B2 (en) | 2010-11-18 | 2015-06-23 | Boston Scientific Scime, Inc. | Catheter-focused magnetic field induced renal nerve ablation |
US9023034B2 (en) | 2010-11-22 | 2015-05-05 | Boston Scientific Scimed, Inc. | Renal ablation electrode with force-activatable conduction apparatus |
US9192435B2 (en) | 2010-11-22 | 2015-11-24 | Boston Scientific Scimed, Inc. | Renal denervation catheter with cooled RF electrode |
US20120157993A1 (en) | 2010-12-15 | 2012-06-21 | Jenson Mark L | Bipolar Off-Wall Electrode Device for Renal Nerve Ablation |
US9220561B2 (en) | 2011-01-19 | 2015-12-29 | Boston Scientific Scimed, Inc. | Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury |
US20140357558A1 (en) * | 2011-06-24 | 2014-12-04 | Cold Spring Harbor Laboratory | Compositions and methods for treatment of spinal muscular atrophy |
WO2013013156A2 (en) | 2011-07-20 | 2013-01-24 | Boston Scientific Scimed, Inc. | Percutaneous devices and methods to visualize, target and ablate nerves |
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FR3000746A1 (fr) | 2013-01-04 | 2014-07-11 | Centre Nat Rech Scient | Peptide pour son utilisation dans le traitement des neuronopathies motrices |
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KR20220148230A (ko) | 2020-02-28 | 2022-11-04 | 아이오니스 파마수티컬즈, 인코포레이티드 | Smn2를 조절하기 위한 화합물 및 방법 |
EP4351558A1 (en) * | 2021-06-10 | 2024-04-17 | Ness Therapeutics, Inc. | Compounds having 5-(2-fluoro-6-hydroxyphenyl)-1,2,5-thiadiazolidin-3-one 1,1-dioxide as inhibitors of protein kinase phosphatase enzymes |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6605753B1 (en) * | 1998-07-24 | 2003-08-12 | Merck & Co., Inc. | Protein tyrosine phosphate-1B (PTP-1B) deficient mice and uses thereof |
WO2007067613A1 (en) * | 2005-12-08 | 2007-06-14 | Novartis Ag | 1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (ptpase) |
WO2008067527A1 (en) * | 2006-12-01 | 2008-06-05 | Novartis Ag | Inhibitors of protein tyrosine phosphatase for the treatment of muscle atrophy and related disorders |
-
2008
- 2008-12-01 EP EP08855205A patent/EP2227245A2/en not_active Withdrawn
- 2008-12-01 US US12/744,813 patent/US20100305036A1/en not_active Abandoned
- 2008-12-01 CA CA2707117A patent/CA2707117A1/en not_active Abandoned
- 2008-12-01 EA EA201000865A patent/EA201000865A1/ru unknown
- 2008-12-01 BR BRPI0819703-2A patent/BRPI0819703A2/pt not_active IP Right Cessation
- 2008-12-01 KR KR1020107014384A patent/KR20100102626A/ko not_active Application Discontinuation
- 2008-12-01 CN CN2008801185968A patent/CN101883579A/zh active Pending
- 2008-12-01 AU AU2008328683A patent/AU2008328683A1/en not_active Abandoned
- 2008-12-01 JP JP2010535405A patent/JP2011504918A/ja active Pending
- 2008-12-01 MX MX2010005909A patent/MX2010005909A/es not_active Application Discontinuation
- 2008-12-01 WO PCT/EP2008/066554 patent/WO2009068689A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CA2707117A1 (en) | 2009-06-04 |
WO2009068689A3 (en) | 2009-08-06 |
EP2227245A2 (en) | 2010-09-15 |
MX2010005909A (es) | 2010-06-23 |
CN101883579A (zh) | 2010-11-10 |
US20100305036A1 (en) | 2010-12-02 |
KR20100102626A (ko) | 2010-09-24 |
WO2009068689A2 (en) | 2009-06-04 |
EA201000865A1 (ru) | 2010-12-30 |
JP2011504918A (ja) | 2011-02-17 |
AU2008328683A1 (en) | 2009-06-04 |
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