BRPI0815889A2 - Análise do perfil de glicosilação. - Google Patents
Análise do perfil de glicosilação.Info
- Publication number
- BRPI0815889A2 BRPI0815889A2 BRPI0815889-4A2A BRPI0815889A BRPI0815889A2 BR PI0815889 A2 BRPI0815889 A2 BR PI0815889A2 BR PI0815889 A BRPI0815889 A BR PI0815889A BR PI0815889 A2 BRPI0815889 A2 BR PI0815889A2
- Authority
- BR
- Brazil
- Prior art keywords
- profile analysis
- glycosylation profile
- glycosylation
- analysis
- profile
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07017063 | 2007-08-31 | ||
PCT/EP2008/006835 WO2009027041A1 (en) | 2007-08-31 | 2008-08-20 | Glycosylation profile analysis |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0815889A2 true BRPI0815889A2 (pt) | 2014-10-14 |
Family
ID=38596692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0815889-4A2A BRPI0815889A2 (pt) | 2007-08-31 | 2008-08-20 | Análise do perfil de glicosilação. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20110117601A1 (pt) |
EP (1) | EP2188382A1 (pt) |
JP (1) | JP2010536355A (pt) |
KR (1) | KR20100038235A (pt) |
CN (1) | CN101784670A (pt) |
AU (1) | AU2008291358A1 (pt) |
BR (1) | BRPI0815889A2 (pt) |
CA (1) | CA2697091A1 (pt) |
IL (1) | IL202566A0 (pt) |
RU (1) | RU2010112236A (pt) |
TW (1) | TW200916585A (pt) |
WO (1) | WO2009027041A1 (pt) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012032203A (ja) * | 2010-07-29 | 2012-02-16 | Sumitomo Bakelite Co Ltd | 抗体の糖鎖を調製する方法 |
EP2616809B1 (en) * | 2010-09-17 | 2017-04-05 | Prozyme, Inc. | Isolation and deglycosylation of glycoproteins |
JP5990000B2 (ja) * | 2011-01-31 | 2016-09-07 | 公益財団法人野口研究所 | Maldi質量分析法用測定試料調製方法 |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
BR112014001120A2 (pt) * | 2011-07-20 | 2017-02-21 | Zepteon Incorporated | métodos de separação de polipeptídeos |
US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
WO2013176754A1 (en) | 2012-05-24 | 2013-11-28 | Abbvie Inc. | Novel purification of antibodies using hydrophobic interaction chromatography |
US9206390B2 (en) | 2012-09-02 | 2015-12-08 | Abbvie, Inc. | Methods to control protein heterogeneity |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
US9310344B2 (en) | 2013-06-14 | 2016-04-12 | Dionex Corporation | HILIC/anion-exchange/cation-exchange multimodal media |
US9169331B2 (en) * | 2012-12-21 | 2015-10-27 | Dionex Corporation | Separation of glycans by mixed-mode liquid chromatography |
WO2014143205A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
US9217168B2 (en) | 2013-03-14 | 2015-12-22 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
US8956830B2 (en) | 2013-03-14 | 2015-02-17 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
EP3754012A1 (en) * | 2013-03-15 | 2020-12-23 | Alder Biopharmaceuticals, Inc. | Antibody purification and purity monitoring |
GB201315705D0 (en) * | 2013-09-04 | 2013-10-16 | Univ Dublin | Methods for predicting, diagmosing or monitoring infections |
EP3052640A2 (en) | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
TWI642782B (zh) | 2013-10-23 | 2018-12-01 | 健臻公司 | 重組醣蛋白及其用途 |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
CN103983684B (zh) * | 2014-04-14 | 2016-08-17 | 南昌大学 | 一种高效的maldi板上的糖基化抑制剂筛选方法 |
JP6750148B2 (ja) * | 2014-04-25 | 2020-09-02 | 公益財団法人野口研究所 | 糖鎖切断抗体の製造方法及び均一糖鎖抗体 |
CN106459118B (zh) | 2014-04-30 | 2019-09-24 | 贝克曼考尔特公司 | 聚糖样品制备 |
WO2015184325A2 (en) * | 2014-05-30 | 2015-12-03 | New England Biolabs, Inc. | Deglycosylation reagents and methods |
EP2975401B1 (en) * | 2014-07-18 | 2019-12-25 | Hexal AG | Improved method of mapping glycans of glycoproteins in serum samples |
JP6344117B2 (ja) * | 2014-07-25 | 2018-06-20 | 株式会社島津製作所 | 磁性ビーズを用いた糖鎖又は糖ペプチドの精製濃縮方法 |
US9908932B2 (en) * | 2014-10-15 | 2018-03-06 | Alexion Pharmaceuticals, Inc. | Methods of shifting an isoelectric profile of a protein product and uses thereof |
WO2016187341A1 (en) * | 2015-05-18 | 2016-11-24 | The Regents Of The University Of California | Systems and methods for predicting glycosylation on proteins |
CN105277718B (zh) * | 2015-09-29 | 2018-03-20 | 上海知先生物科技有限公司 | 用于恶性肿瘤相关筛查及评估的产品、应用及方法 |
US11680948B2 (en) | 2016-08-12 | 2023-06-20 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
JP6850351B2 (ja) * | 2016-12-21 | 2021-03-31 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 抗体のインビトロ糖鎖工学 |
EP3559249A1 (en) | 2016-12-21 | 2019-10-30 | H. Hoffnabb-La Roche Ag | Method for in vitro glycoengineering of antibodies |
EP3662287B1 (en) * | 2017-08-01 | 2024-02-28 | Amgen Inc. | Systems and methods for real time preparation of a polypeptide sample for anaylsis with mass spectrometry |
WO2019028191A1 (en) * | 2017-08-01 | 2019-02-07 | Amgen Inc. | SYSTEMS AND METHODS FOR PERFORMING REAL-TIME GLYCAN ASSAY OF A SAMPLE |
SG11202110968VA (en) | 2019-12-06 | 2021-10-28 | Regeneron Pharma | Anti-vegf protein compositions and methods for producing the same |
CN115078728A (zh) * | 2021-03-11 | 2022-09-20 | 盛禾(中国)生物制药有限公司 | 一种融合蛋白的快速分析方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1587408A4 (en) * | 2002-12-20 | 2007-09-05 | Momenta Pharmaceuticals Inc | GLYCAN MARKER FOR DIAGNOSIS AND MONITORING OF DISEASES |
CA2608818A1 (en) * | 2005-06-03 | 2006-12-14 | Genentech, Inc. | Method of producing antibodies with modified fucosylation level |
JP2009509970A (ja) * | 2005-09-22 | 2009-03-12 | プロサイ インコーポレイテッド | 酵母突然変異体において産生されるグリコシル化ポリペプチドおよびその使用方法 |
-
2008
- 2008-08-20 WO PCT/EP2008/006835 patent/WO2009027041A1/en active Application Filing
- 2008-08-20 CN CN200880104294A patent/CN101784670A/zh active Pending
- 2008-08-20 BR BRPI0815889-4A2A patent/BRPI0815889A2/pt not_active IP Right Cessation
- 2008-08-20 AU AU2008291358A patent/AU2008291358A1/en not_active Abandoned
- 2008-08-20 CA CA2697091A patent/CA2697091A1/en not_active Abandoned
- 2008-08-20 US US12/674,980 patent/US20110117601A1/en not_active Abandoned
- 2008-08-20 EP EP08785644A patent/EP2188382A1/en not_active Withdrawn
- 2008-08-20 JP JP2010521356A patent/JP2010536355A/ja active Pending
- 2008-08-20 KR KR1020107004464A patent/KR20100038235A/ko not_active Application Discontinuation
- 2008-08-20 RU RU2010112236/10A patent/RU2010112236A/ru not_active Application Discontinuation
- 2008-08-29 TW TW097133322A patent/TW200916585A/zh unknown
-
2009
- 2009-12-07 IL IL202566A patent/IL202566A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
RU2010112236A (ru) | 2011-10-10 |
TW200916585A (en) | 2009-04-16 |
WO2009027041A1 (en) | 2009-03-05 |
EP2188382A1 (en) | 2010-05-26 |
IL202566A0 (en) | 2010-06-30 |
CA2697091A1 (en) | 2009-03-05 |
KR20100038235A (ko) | 2010-04-13 |
CN101784670A (zh) | 2010-07-21 |
US20110117601A1 (en) | 2011-05-19 |
JP2010536355A (ja) | 2010-12-02 |
AU2008291358A1 (en) | 2009-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
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B350 | Update of information on the portal [chapter 15.35 patent gazette] |