BRPI0815602A2 - PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM - Google Patents
PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEMInfo
- Publication number
- BRPI0815602A2 BRPI0815602A2 BRPI0815602-6A2A BRPI0815602A BRPI0815602A2 BR PI0815602 A2 BRPI0815602 A2 BR PI0815602A2 BR PI0815602 A BRPI0815602 A BR PI0815602A BR PI0815602 A2 BRPI0815602 A2 BR PI0815602A2
- Authority
- BR
- Brazil
- Prior art keywords
- trimethyzidine
- preparing
- proposed
- release compositions
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1533MU2007 | 2007-08-08 | ||
PCT/IN2008/000493 WO2009066315A2 (en) | 2007-08-08 | 2008-08-07 | Sustained release compositions of trimetazidine and process for preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0815602A2 true BRPI0815602A2 (en) | 2015-03-03 |
Family
ID=40667940
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0815602-6A2A BRPI0815602A2 (en) | 2007-08-08 | 2008-08-07 | PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2187874A2 (en) |
BR (1) | BRPI0815602A2 (en) |
WO (1) | WO2009066315A2 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010084397A2 (en) * | 2009-01-20 | 2010-07-29 | Micro Labs Limited | Modified release solid pharmaceutical compositions of trimetazidine and process thereof |
TR201001902A2 (en) * | 2010-03-12 | 2011-04-21 | Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. | Trimetazidine tablets with extended release |
ES2508490T3 (en) * | 2010-05-04 | 2014-10-16 | Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi | Formulation of trimetazidine with different release profiles |
EP2386302A1 (en) * | 2010-05-11 | 2011-11-16 | Ranbaxy Laboratories Limited | A controlled release pharmaceutical dosage form of trimetazidine and processes for the preparation thereof |
WO2013180676A1 (en) * | 2012-05-28 | 2013-12-05 | Mahmut Bilgic | A new sustained release formulation |
CN105434380A (en) * | 2015-12-11 | 2016-03-30 | 南京正科医药股份有限公司 | Trimetazidine dihydrochloride tablet |
WO2018094387A1 (en) * | 2016-11-21 | 2018-05-24 | Saghmos Therapeutics, Inc. | Prevention and/or treatment of contrast-induced acute kidney injury |
CA3068254A1 (en) | 2017-06-20 | 2018-12-27 | Imbria Pharmaceuticals, Inc. | Compositions and methods for increasing efficiency of cardiac metabolism |
CN110623934B (en) * | 2019-09-26 | 2022-05-13 | 杭州百诚医药科技股份有限公司 | Trimetazidine hydrochloride sustained release tablet and preparation method thereof |
US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
CN111888476A (en) * | 2020-08-17 | 2020-11-06 | 深圳市道科思医药有限公司 | Modified release pharmaceutical composition of trimetazidine dihydrochloride |
CN112315942B (en) * | 2020-11-04 | 2022-08-09 | 南京康川济医药科技有限公司 | Trimetazidine hydrochloride sustained release preparation and preparation method thereof |
US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1195160E (en) * | 2000-10-05 | 2009-12-07 | Usv Ltd | Sustained release trimetazidine pharmaceutical compositions and a method of their preparation |
FR2818549B1 (en) * | 2000-12-26 | 2003-02-07 | Servier Lab | SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF TRIMETAZIDINE |
FR2885807B1 (en) * | 2005-05-18 | 2008-05-16 | Mg Pharma | SOLID PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE, AND PREPARATION METHOD |
-
2008
- 2008-08-07 WO PCT/IN2008/000493 patent/WO2009066315A2/en active Application Filing
- 2008-08-07 EP EP08852448A patent/EP2187874A2/en not_active Withdrawn
- 2008-08-07 BR BRPI0815602-6A2A patent/BRPI0815602A2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2009066315A2 (en) | 2009-05-28 |
WO2009066315A3 (en) | 2009-09-24 |
EP2187874A2 (en) | 2010-05-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |