BRPI0813011A2 - Formulação injetável aquosa estéril, processo de preparação da mesma e sua utilização - Google Patents
Formulação injetável aquosa estéril, processo de preparação da mesma e sua utilizaçãoInfo
- Publication number
- BRPI0813011A2 BRPI0813011A2 BRPI0813011A BRPI0813011A2 BR PI0813011 A2 BRPI0813011 A2 BR PI0813011A2 BR PI0813011 A BRPI0813011 A BR PI0813011A BR PI0813011 A2 BRPI0813011 A2 BR PI0813011A2
- Authority
- BR
- Brazil
- Prior art keywords
- preparation process
- injectable formulation
- water injectable
- water
- formulation
- Prior art date
Links
- 239000007972 injectable composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0704772A FR2918276B1 (fr) | 2007-07-02 | 2007-07-02 | "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires" |
FR0704772 | 2007-07-02 | ||
PCT/FR2008/000948 WO2009024670A2 (fr) | 2007-07-02 | 2008-07-02 | Gel injectable d ' acide hyaluronique pour le traitement des degenerescences articulaires |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0813011A2 true BRPI0813011A2 (pt) | 2014-12-23 |
BRPI0813011B1 BRPI0813011B1 (pt) | 2019-10-08 |
BRPI0813011B8 BRPI0813011B8 (pt) | 2021-05-25 |
Family
ID=39167393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0813011A BRPI0813011B8 (pt) | 2007-07-02 | 2008-07-02 | formulação injetável aquosa estéril, processo de preparação da mesma e sua utilização |
Country Status (14)
Country | Link |
---|---|
US (1) | US9138405B2 (pt) |
EP (2) | EP3498262B1 (pt) |
JP (1) | JP5517133B2 (pt) |
KR (1) | KR20100028582A (pt) |
CN (2) | CN104825482A (pt) |
BR (1) | BRPI0813011B8 (pt) |
CA (1) | CA2691600C (pt) |
ES (2) | ES2898939T3 (pt) |
FR (1) | FR2918276B1 (pt) |
HU (1) | HUE056793T2 (pt) |
PL (2) | PL2173324T3 (pt) |
PT (2) | PT2173324T (pt) |
TR (1) | TR201909779T4 (pt) |
WO (1) | WO2009024670A2 (pt) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2945949B1 (fr) | 2009-05-26 | 2011-05-13 | Anteis Sa | Hydrogel injectable permettant une supplementation en glycerol dans la peau sur le long terme. |
US8273725B2 (en) | 2009-09-10 | 2012-09-25 | Genzyme Corporation | Stable hyaluronan/steroid formulation |
FR2954165B1 (fr) | 2009-12-18 | 2012-01-13 | Jean-Noel Thorel | Compositions injectables a usage intra-articulaire associant un agent de viscosupplementation et un milieu de croissance des fibroblastes |
JP5457238B2 (ja) * | 2010-03-17 | 2014-04-02 | 電気化学工業株式会社 | ヒアルロン酸及び/又はその塩の含有液の加熱滅菌方法 |
IT1402382B1 (it) * | 2010-09-09 | 2013-09-04 | Ibsa Inst Biochimique Sa | Complessi cooperativi ibridi di acido ialuronico |
US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US20140038917A1 (en) * | 2011-04-19 | 2014-02-06 | Anteis S.A. | Sterile and injectable aqueous formulation for administration in the intra-articular space of an intra-articular joint |
US8623839B2 (en) * | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
GB201118586D0 (en) * | 2011-10-27 | 2011-12-07 | Turzi Antoine | New A-PRP medical device, manufacturing machine and process |
WO2013076162A1 (en) * | 2011-11-21 | 2013-05-30 | Université Libre de Bruxelles | Formulations useful in the treatment of osteoarticular diseases |
WO2013076160A1 (en) * | 2011-11-21 | 2013-05-30 | Université Libre de Bruxelles | Sustained release formulations useful in the treatment of diseases |
FR2991876B1 (fr) | 2012-06-13 | 2014-11-21 | Vivacy Lab | Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate |
FR2994846B1 (fr) | 2012-08-29 | 2014-12-26 | Vivacy Lab | Composition, sterilisee, comprenant au moins un acide hyaluronique et de l'ascorbyl phosphate de magnesium |
KR20150104202A (ko) * | 2013-01-11 | 2015-09-14 | 카르빌란 테라퓨틱스, 인코포레이티드 | 히알루론산을 포함하는 안정화된 조성물 |
ES2837626T3 (es) | 2013-07-10 | 2021-07-01 | Matrix Biology Inst | Composiciones de hialuronano con alta elasticidad y usos de las mismas |
KR101582380B1 (ko) * | 2013-09-11 | 2016-01-05 | 주식회사 제네웰 | 손상 조직에 대한 세포 전달 및 조직 재생용 생체재료와 제조방법 |
EP3074427B1 (en) | 2013-11-25 | 2021-01-06 | Deuteria Biomaterials, LLC | Deuterium-enriched hyaluronan |
US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
FR3032617B1 (fr) * | 2015-02-16 | 2018-03-16 | Kylane Laboratoires Sa | Procede de preparation d un hydrogel injectable; hydrogel obtenu; utilisation de l hydrogel obtenu |
RU2727809C2 (ru) | 2015-09-24 | 2020-07-24 | Матрикс Байолэджи Инститьют | Композиции гиалуроновой кислоты с высокоэластичными свойствами и способы их применения |
CN105879124B (zh) * | 2016-04-26 | 2019-03-19 | 华熙福瑞达生物医药有限公司 | 一种注射用左旋聚乳酸填充剂及其制备方法 |
KR101916193B1 (ko) | 2016-08-25 | 2018-11-07 | 주식회사 파마리서치프로덕트 | 핵산 및 키토산을 포함하는 관절강 주사용 조성물 |
US10576099B2 (en) | 2016-10-21 | 2020-03-03 | Covidien Lp | Injectable scaffold for treatment of intracranial aneurysms and related technology |
FR3063649B1 (fr) | 2017-03-07 | 2021-05-21 | Laboratoire De Rhumatologie Appliquee | Nouvelle solution visco-elastique et son utilisation en rhumatologie |
CN111065423B (zh) * | 2017-08-22 | 2022-04-12 | 莫比斯医疗有限公司 | 用于关节润滑的脂质体制剂 |
IT201800007683A1 (it) | 2018-07-31 | 2020-01-31 | Altergon Sa | Composizioni cooperative sinergiche utili per aumento del tessuto molle, rilascio di farmaco e campi correlati |
WO2020111888A1 (ko) * | 2018-11-30 | 2020-06-04 | 주식회사 엘지화학 | 히알루론산을 포함하는 활액보충재용 조성물 |
US20220088589A1 (en) | 2019-01-21 | 2022-03-24 | Eclipse Medcorp, Llc | Methods, Systems and Apparatus for Separating Components of a Biological Sample |
US12007382B2 (en) | 2019-10-31 | 2024-06-11 | Crown Laboratories, Inc. | Systems, methods and apparatus for separating components of a sample |
EP3854377A1 (fr) * | 2020-01-22 | 2021-07-28 | Laboratoires Genevrier Sas | Composition comprenant de l'acide hyaluronique et un polyol ou de carboxyméthylcellulose |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL80298A (en) * | 1986-10-14 | 1993-01-31 | Res & Dev Co Ltd | Eye drops |
US5079236A (en) * | 1987-05-27 | 1992-01-07 | Hyal Pharmaceutical Corporation | Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use |
JP2756131B2 (ja) * | 1987-07-01 | 1998-05-25 | ジェネンテク,インコーポレイテッド | フィブリンの沈着または癒着の予防のための方法および治療学的組成物 |
US5095037B1 (en) * | 1989-12-21 | 1995-12-19 | Nissho Kk | Combined anti-inflammatory agent |
JP2788340B2 (ja) * | 1989-12-21 | 1998-08-20 | 株式会社ニッショー | 炎症治療剤 |
CA2060223C (en) * | 1991-02-12 | 1999-07-20 | Clarence C. Lee | Injectable medical lubricating fluid composition and method of use |
US7968110B2 (en) * | 1992-02-11 | 2011-06-28 | Merz Aesthetics, Inc. | Tissue augmentation material and method |
IT1291291B1 (it) * | 1997-04-30 | 1999-01-07 | Chemedica Sa | Uso di acido ialuronico e relativi sali per la preparazione di una soluzione acquosa utile come liquido di lavaggio intra-articolare |
EP1465596A1 (en) * | 2002-01-18 | 2004-10-13 | Control Delivery Systems, Inc. | Polymeric gel system for the controlled delivery of codrugs |
WO2004073759A1 (en) | 2003-02-19 | 2004-09-02 | Aventis Pharmaceuticals Holdings Inc. | Composition and method for intradermal soft tissue augmentation |
US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
FR2865737B1 (fr) * | 2004-02-03 | 2006-03-31 | Anteis Sa | Gel reticule biocompatible |
US20050215516A1 (en) * | 2004-03-29 | 2005-09-29 | Claudio Bucolo | New free-radical scavenger containing viscoelastic composition, methods of use and package |
CA2577022A1 (en) * | 2004-08-13 | 2006-02-23 | Angiotech International Ag | Compositions and methods using hyaluronic acid and hyluronidase inhibitors |
WO2006067608A1 (en) * | 2004-12-22 | 2006-06-29 | Laboratoire Medidom S.A. | Aqueous formulations based on sodium hyaluronate for parenteral use |
FR2895907B1 (fr) * | 2006-01-06 | 2012-06-01 | Anteis Sa | Gel viscoelastique a usage dermatologique |
FR2909560B1 (fr) | 2006-12-06 | 2012-12-28 | Fabre Pierre Dermo Cosmetique | Gel d'acide hyaluronique pour injection intradermique |
-
2007
- 2007-07-02 FR FR0704772A patent/FR2918276B1/fr active Active
-
2008
- 2008-07-02 ES ES19156054T patent/ES2898939T3/es active Active
- 2008-07-02 JP JP2010514043A patent/JP5517133B2/ja active Active
- 2008-07-02 HU HUE19156054A patent/HUE056793T2/hu unknown
- 2008-07-02 ES ES08827889T patent/ES2735376T3/es active Active
- 2008-07-02 KR KR20097027301A patent/KR20100028582A/ko not_active Application Discontinuation
- 2008-07-02 TR TR2019/09779T patent/TR201909779T4/tr unknown
- 2008-07-02 EP EP19156054.9A patent/EP3498262B1/fr active Active
- 2008-07-02 PL PL08827889T patent/PL2173324T3/pl unknown
- 2008-07-02 PT PT08827889T patent/PT2173324T/pt unknown
- 2008-07-02 WO PCT/FR2008/000948 patent/WO2009024670A2/fr active Application Filing
- 2008-07-02 CN CN201510090635.XA patent/CN104825482A/zh active Pending
- 2008-07-02 PL PL19156054T patent/PL3498262T3/pl unknown
- 2008-07-02 US US12/667,627 patent/US9138405B2/en active Active
- 2008-07-02 EP EP08827889.0A patent/EP2173324B1/fr active Active
- 2008-07-02 CN CN200880023126A patent/CN101686936A/zh active Pending
- 2008-07-02 PT PT191560549T patent/PT3498262T/pt unknown
- 2008-07-02 CA CA2691600A patent/CA2691600C/fr active Active
- 2008-07-02 BR BRPI0813011A patent/BRPI0813011B8/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP2173324A2 (fr) | 2010-04-14 |
EP3498262A1 (fr) | 2019-06-19 |
HUE056793T2 (hu) | 2022-03-28 |
US20100184720A1 (en) | 2010-07-22 |
CN104825482A (zh) | 2015-08-12 |
PT2173324T (pt) | 2019-07-09 |
CA2691600C (fr) | 2017-01-10 |
EP3498262B1 (fr) | 2021-09-01 |
KR20100028582A (ko) | 2010-03-12 |
TR201909779T4 (tr) | 2019-07-22 |
FR2918276B1 (fr) | 2010-01-22 |
US9138405B2 (en) | 2015-09-22 |
WO2009024670A3 (fr) | 2009-04-23 |
FR2918276A1 (fr) | 2009-01-09 |
CN101686936A (zh) | 2010-03-31 |
ES2735376T3 (es) | 2019-12-18 |
ES2898939T3 (es) | 2022-03-09 |
PL2173324T3 (pl) | 2019-09-30 |
CA2691600A1 (fr) | 2009-02-26 |
WO2009024670A2 (fr) | 2009-02-26 |
PT3498262T (pt) | 2021-11-11 |
EP2173324B1 (fr) | 2019-04-10 |
JP5517133B2 (ja) | 2014-06-11 |
JP2010531863A (ja) | 2010-09-30 |
PL3498262T3 (pl) | 2022-02-07 |
BRPI0813011B8 (pt) | 2021-05-25 |
BRPI0813011B1 (pt) | 2019-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: APTISSEN SA (CH) |
|
B25D | Requested change of name of applicant approved |
Owner name: APTISSEN SA (CH) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/10/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/10/2019, OBSERVADAS AS CONDICOES LEGAIS |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
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