BRPI0519242A2 - uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar - Google Patents

uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar

Info

Publication number
BRPI0519242A2
BRPI0519242A2 BRPI0519242-0A BRPI0519242A BRPI0519242A2 BR PI0519242 A2 BRPI0519242 A2 BR PI0519242A2 BR PI0519242 A BRPI0519242 A BR PI0519242A BR PI0519242 A2 BRPI0519242 A2 BR PI0519242A2
Authority
BR
Brazil
Prior art keywords
treatment
multiple sclerosis
emotional instability
pseudobulbar paralysis
aminocyclohexane derivatives
Prior art date
Application number
BRPI0519242-0A
Other languages
English (en)
Inventor
Jeffrey Jonas
Allison Mann
Wojciech Danysz
Christopher Graham Raphael Parsons
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of BRPI0519242A2 publication Critical patent/BRPI0519242A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

USO DE DERIVADOS DE l-AMINOCICLOHEXANO PARA O TRATAMENTO DE ESCLEROSE MéLTIPLA, INSTABILIDADE EMOCIONAL E PARALISIA PSEUDOBULBAR. A presente invenção relaciona-se ao tratamento de indivíduos diagnosticados com esclerose múltipla, instabilidade emocional ou paralisia pseudobulbar que compreende a administração ao referido individual de uma quantidade eficaz.de um derivado de l-aminociclohexano, ou seja, especialmente memantina ou neramexano.
BRPI0519242-0A 2004-12-22 2005-12-22 uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar BRPI0519242A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63842304P 2004-12-22 2004-12-22
PCT/US2005/046733 WO2006069294A1 (en) 2004-12-22 2005-12-22 1-aminocyclohexane-derivatives for the treatment of multiple sclerosis emotional lability and pseudobulbar affect

Publications (1)

Publication Number Publication Date
BRPI0519242A2 true BRPI0519242A2 (pt) 2009-01-06

Family

ID=36084339

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0519242-0A BRPI0519242A2 (pt) 2004-12-22 2005-12-22 uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar

Country Status (13)

Country Link
US (2) US20060205822A1 (pt)
EP (1) EP1838297A1 (pt)
JP (1) JP2008525488A (pt)
KR (1) KR20070086507A (pt)
CN (1) CN101087599A (pt)
AU (1) AU2005319078A1 (pt)
BR (1) BRPI0519242A2 (pt)
CA (1) CA2589671A1 (pt)
EA (1) EA200701351A1 (pt)
IL (1) IL183963A0 (pt)
MX (1) MX2007007416A (pt)
WO (1) WO2006069294A1 (pt)
ZA (1) ZA200705112B (pt)

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JP5882208B2 (ja) * 2009-07-30 2016-03-09 テバ ファーマシューティカル インダストリーズ リミティド ラキニモドによるクローン病の治療
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MX337614B (es) * 2010-03-03 2016-03-10 Teva Pharma Tratamiento de lupus nefritis usando laquinimod.
WO2012048871A1 (en) * 2010-10-12 2012-04-19 Merz Pharma Gmbh & Co. Kgaa Memantine for improving cognitive performance in subjects
EP2640391B1 (en) 2010-11-15 2015-11-11 Agenebio, Inc. Pyridazine derivatives, compositions and methods for treating cognitive impairment
KR20130124518A (ko) * 2010-12-07 2013-11-14 테바 파마슈티컬 인더스트리즈 리미티드 다발경화증 환자의 피로를 감소시키고, 기능 상태를 개선시키고, 삶의 질을 개선시키기 위한 라퀴니모드의 용도
CN102241678B (zh) 2011-04-26 2014-10-29 辽宁利锋科技开发有限公司 含有脂环结构化合物的抗肿瘤作用与应用
EP2766020A4 (en) 2011-10-12 2015-04-01 Teva Pharma TREATMENT OF MULTIPLE SCLEROSIS BY COMBINING LAQUINIMOD AND FINGOLIMOD
SG11201404214QA (en) 2012-02-03 2014-08-28 Teva Pharma USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
AU2013361057A1 (en) * 2012-12-21 2015-07-30 Teva Pharmaceutical Industries Ltd. Oral transmucosal delivery of glatiramer acetate
TWI508461B (zh) * 2013-01-04 2015-11-11 Mstar Semiconductor Inc 適用於數位電視廣播系統的信號處理方法以及接收器
WO2015095783A1 (en) 2013-12-20 2015-06-25 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
SG11201608674UA (en) 2014-04-29 2016-11-29 Teva Pharma Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status
JP6987384B2 (ja) 2015-06-19 2021-12-22 エージンバイオ， インコーポレイテッド ベンゾジアゼピン誘導体、組成物、および認知障害を処置するための方法
EP3474831A1 (en) 2016-06-23 2019-05-01 Corium International, Inc. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
KR102424270B1 (ko) 2016-07-27 2022-07-25 코리움, 인크. 경구 전달과 생물학적으로 동등한 약물동역학을 가진 경피 전달 시스템
SG11201900712SA (en) 2016-07-27 2019-02-27 Corium Int Inc Memantine transdermal delivery systems
CN109789106B (zh) 2016-07-27 2023-06-27 考里安有限责任公司 碳酸氢钠原位转化驱动胺药物的透皮递送
US20180170941A1 (en) 2016-12-19 2018-06-21 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US11505555B2 (en) 2016-12-19 2022-11-22 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
WO2019126531A1 (en) 2017-12-20 2019-06-27 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
BR112020026062B1 (pt) 2018-06-19 2023-04-04 Agenebio, Inc Compostos derivados de benzodiazepina ou um sal farmaceuticamente aceitavel, isômero ou combinação dos mesmos, composição farmacêutica compreendendo os mesmos e usos dos mesmos para o tratamento de comprometimento cognitivo, câncer cerebral e psicose da doença de parkinson
EP4103187A4 (en) * 2020-02-10 2024-04-10 Woolsey Pharmaceuticals, Inc. METHODS FOR TREATING PSEUDOBULBAR AFFECTION AND OTHER EMOTIONAL DISORDERS
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Also Published As

Publication number Publication date
CN101087599A (zh) 2007-12-12
CA2589671A1 (en) 2006-06-29
MX2007007416A (es) 2007-08-15
KR20070086507A (ko) 2007-08-27
EP1838297A1 (en) 2007-10-03
WO2006069294A1 (en) 2006-06-29
US20090081259A1 (en) 2009-03-26
EA200701351A1 (ru) 2007-12-28
US20060205822A1 (en) 2006-09-14
JP2008525488A (ja) 2008-07-17
AU2005319078A1 (en) 2006-06-29
ZA200705112B (en) 2008-10-29
IL183963A0 (en) 2008-12-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.