BRPI0516327A - sistemas de policetìdeo sintase de pufa e usos dos mesmos - Google Patents
sistemas de policetìdeo sintase de pufa e usos dos mesmosInfo
- Publication number
- BRPI0516327A BRPI0516327A BRPI0516327-7A BRPI0516327A BRPI0516327A BR PI0516327 A BRPI0516327 A BR PI0516327A BR PI0516327 A BRPI0516327 A BR PI0516327A BR PI0516327 A BRPI0516327 A BR PI0516327A
- Authority
- BR
- Brazil
- Prior art keywords
- systems
- pks
- pufa
- relates
- polyketide synthase
- Prior art date
Links
- 108010030975 Polyketide Synthases Proteins 0.000 title abstract 8
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 9
- 244000005700 microbiome Species 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 235000003869 genetically modified organism Nutrition 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
SISTEMAS DE POLICETìDEO SINTASE DE PUFA E USOS DOS MESMOS. Esta invenção se refere a sistemas de policetídeo sintase (PKS) de ácido grado poliinsaturado (PUFA) de microorganismos bacterianos. Mais especificamente, esta invenção se refere a ácidos nucléicos codificando sistemas PKS PUFA, a proteínas e domínios dos mesmos que compreendem sistema PKS PUFA, a organismos geneticamente modificados compreendendo estes sistemas PKS PUFA, e a métodos para fazer e usar os sistemas PKS PUFA revelados aqui. Esta invenção também se refere a plantas e microorganismos geneticamente modificados e a métodos para produzir eficientemente lipídeos enriquecidos em vários ácidos graxos poliinsaturados (PUFAs) por manipulação de um sistema de policetídeo sintase (PKS) de PUFA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/965,017 US7217856B2 (en) | 1999-01-14 | 2004-10-13 | PUFA polyketide synthase systems and uses thereof |
PCT/US2005/036998 WO2006044646A2 (en) | 2004-10-13 | 2005-10-13 | Pufa polyketide synthase systems and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0516327A true BRPI0516327A (pt) | 2008-09-02 |
Family
ID=36203549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0516327-7A BRPI0516327A (pt) | 2004-10-13 | 2005-10-13 | sistemas de policetìdeo sintase de pufa e usos dos mesmos |
Country Status (11)
Country | Link |
---|---|
US (15) | US7217856B2 (pt) |
EP (1) | EP1805315A4 (pt) |
JP (1) | JP2008515461A (pt) |
KR (1) | KR20070084187A (pt) |
CN (1) | CN101437950A (pt) |
AU (1) | AU2005295598A1 (pt) |
BR (1) | BRPI0516327A (pt) |
CA (1) | CA2584004A1 (pt) |
IL (1) | IL182548A0 (pt) |
MX (1) | MX2007004502A (pt) |
WO (1) | WO2006044646A2 (pt) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
US7271315B2 (en) * | 1999-01-14 | 2007-09-18 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US7211418B2 (en) | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
US7807849B2 (en) | 2004-04-22 | 2010-10-05 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
CA3023314C (en) | 2004-04-22 | 2019-12-10 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
EP2630869B1 (en) | 2005-07-01 | 2016-12-14 | DSM IP Assets B.V. | Polyunsaturated fatty acid-containing oil product and uses and production thereof |
KR101524398B1 (ko) * | 2006-03-15 | 2015-06-04 | 디에스엠 아이피 어셋츠 비.브이. | Pufa 폴리케티드 신타제 시스템을 이용한 이종 생물체내 다불포화 지방산의 제조 |
CN101473038B (zh) * | 2006-03-15 | 2014-05-28 | Dsmip资产公司 | 含有多不饱和脂肪酸的植物种子油 |
CN101466270A (zh) * | 2006-04-11 | 2009-06-24 | 马泰克生物科学公司 | 包含长链多不饱和脂肪酸的食品及其制备方法 |
ES2668640T5 (es) | 2006-06-22 | 2022-05-12 | Dsm Ip Assets Bv | Composiciones de compuestos lábiles encapsulados y métodos para preparar las mismas |
EP2059588A4 (en) | 2006-08-29 | 2010-07-28 | Commw Scient Ind Res Org | FATTY ACID SYNTHESIS |
MY152880A (en) | 2006-08-29 | 2014-11-28 | Dsm Ip Assets Bv | Use of dpa(n-6) oils in infant formula |
US20080233628A1 (en) * | 2006-09-14 | 2008-09-25 | The Salk Institute For Biological Studies | Incorporation of type III polyketide synthases into multidomain proteins of the type I and III polyketide synthase and fatty acid synthase families |
WO2009006317A1 (en) * | 2007-06-29 | 2009-01-08 | Martek Biosciences Corporation | Production and purification of esters of polyunsaturated fatty acids |
JP5110511B2 (ja) * | 2007-09-05 | 2012-12-26 | 独立行政法人産業技術総合研究所 | 微生物を用いた高度不飽和脂肪酸及び高度不飽和脂質の製造方法 |
US20110076379A1 (en) * | 2008-06-13 | 2011-03-31 | Means Michael M | High omega saturated fat free meat products |
DK2358882T3 (da) | 2008-11-18 | 2017-11-06 | Commw Scient Ind Res Org | Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer |
EP2405018A4 (en) * | 2009-03-04 | 2013-02-20 | Univ Miyazaki | METHOD FOR DETERMINING FATTY ACID SYNTHESIS PATHWAYS OF A MICROORGANISM, AND PCR PRIMER GROUP USED IN SAID METHOD |
CN104263729B (zh) | 2009-03-16 | 2020-09-15 | 帝斯曼知识产权资产有限公司 | 在网粘菌门微生物中产生蛋白质 |
CN102741267B (zh) * | 2009-03-19 | 2020-06-23 | 帝斯曼知识产权资产有限公司 | 多不饱和脂肪酸合酶核酸分子和多肽,及其组合物、制备方法和用途 |
WO2011090730A1 (en) * | 2009-12-28 | 2011-07-28 | Martek Biosciences Corporation | Recombinant thraustochytrids that grow on xylose, and compositions, methods of making, and uses thereof |
TW201144442A (en) | 2010-05-17 | 2011-12-16 | Dow Agrosciences Llc | Production of DHA and other LC-PUFAs in plants |
WO2012021703A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Du Pont De Nemours And Company | A sustainable aquaculture feeding strategy |
WO2012021686A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Du Pont De Nemours And Company | Improved aquaculture meat products |
US20120040076A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Du Pont De Nemours And Company | Aquaculture feed compositions |
CA2823678A1 (en) * | 2010-10-01 | 2012-04-05 | Kyushu University, National University Corporation | Transformation of a stramenopile for production of a microbial oil |
US20140024555A1 (en) * | 2011-03-31 | 2014-01-23 | Los Alamos National Security, Llc | Method of identifying soluble proteins and soluble protein complexes |
TW201307553A (zh) | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術 |
US10385327B2 (en) * | 2012-01-05 | 2019-08-20 | University Of Puerto Rico | Enhanced E. coli for the production of fatty acids and method of producing the same |
KR102197208B1 (ko) | 2012-06-15 | 2021-01-04 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 식물 세포에서 장쇄 다중불포화 지방산의 생성 |
WO2014026162A1 (en) | 2012-08-10 | 2014-02-13 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
US10184140B2 (en) | 2013-01-23 | 2019-01-22 | Iowa State University Research Foundation, Inc. | Materials and methods for production of bi-functional fatty acids in recombinant bacteria |
US9809804B2 (en) | 2013-01-23 | 2017-11-07 | Iowa State University Research Foundation, Inc. | Materials and methods for characterizing and using KASIII for production of bi-functional fatty acids |
US20150119601A1 (en) | 2013-03-15 | 2015-04-30 | Opx Biotechnologies, Inc. | Monofunctional mcr + 3-hp dehydrogenase |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
CN106795483A (zh) | 2013-07-19 | 2017-05-31 | 嘉吉公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
EP2843043A1 (en) * | 2013-08-27 | 2015-03-04 | Evonik Industries AG | A method for producing acyl amino acids |
US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
TW201525136A (zh) | 2013-11-26 | 2015-07-01 | Dow Agrosciences Llc | 利用破囊壺菌PUFA合成酶於油籽作物中生成ω-3長鏈多不飽和脂肪酸 |
PE20170253A1 (es) | 2013-12-18 | 2017-04-14 | Nuseed Pty Ltd | Lipido que comprende acidos grasos poliinsaturados de cadena larga |
WO2015116671A2 (en) | 2014-01-28 | 2015-08-06 | Dsm Ip Assets B.V. | Factors for the production and accumulation of polyunsaturated fatty acids (pufas) derived from pufa synthases |
WO2015134547A1 (en) | 2014-03-03 | 2015-09-11 | Synthetic Genomics, Inc. | Molecules associated with fatty acid biosynthetic pathways and uses thereof |
CA2948896A1 (en) * | 2014-05-08 | 2015-11-12 | Scfm Ventures, Llc | Method for optimizing production of eicosapentaenoic acid (epa) in a recombinant host |
CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
CN105567715B (zh) * | 2014-10-17 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌α-微管蛋白相关序列及其应用 |
WO2016140925A1 (en) | 2015-03-02 | 2016-09-09 | Synthetic Genomics, Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
CN105176942A (zh) * | 2015-08-04 | 2015-12-23 | 北京农学院 | 来源于树莓的聚酮合酶RinPKS1及其相关生物材料与应用 |
CN107529783A (zh) | 2015-10-01 | 2018-01-02 | 帝斯曼知识产权资产管理有限公司 | 用于宠物食品中的补充物质 |
AU2017235543B2 (en) | 2016-03-16 | 2020-05-14 | Conagen, Inc. | Production of proteins in labyrinthulomycetes |
BR112018073164A2 (pt) | 2016-05-12 | 2019-04-30 | Dsm Ip Assets Bv | método de aumento de produção de ácidos graxos poli-insaturados ômega-3 em microalgas |
CN106591388A (zh) * | 2016-10-13 | 2017-04-26 | 中国农业科学院生物技术研究所 | 具有聚酮类化合物合成功能的基因Dr2091 |
EP3532055A4 (en) * | 2016-10-28 | 2020-10-21 | Ginkgo Bioworks Inc. | COMPOSITIONS AND PROCESSES FOR THE PRODUCTION OF COMPOUNDS |
US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
US11345938B2 (en) | 2017-02-02 | 2022-05-31 | Cargill, Incorporated | Genetically modified cells that produce C6-C10 fatty acid derivatives |
CN108753810B (zh) * | 2018-05-22 | 2021-06-18 | 昆明理工大学 | 一种转录调节蛋白基因orf2的用途 |
BR112021002299A2 (pt) * | 2018-08-10 | 2021-05-04 | Kyowa Hakko Bio Co., Ltd | micro-organismo produzindo ácido graxo poli-insaturado e método para produzir ácido graxo poli-insaturado |
US11613728B2 (en) | 2018-08-10 | 2023-03-28 | Kyowa Hakko Bio Co., Ltd. | Microorganism producing eicosapentaenoic acid and method for producing eicosapentaenoic acid |
WO2023070027A2 (en) * | 2021-10-20 | 2023-04-27 | University Of Puerto Rico | Fatty acid production in escherichia coli |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US674574A (en) * | 1900-08-01 | 1901-05-21 | Charles Decrette | Metal-bending machine. |
US781861A (en) * | 1903-11-07 | 1905-02-07 | Alonzo W Allen | Thread or yarn tension device. |
US778594A (en) * | 1904-06-29 | 1904-12-27 | Pancrazio M Megaro | Shaving composition. |
US777277A (en) * | 1904-09-07 | 1904-12-13 | American Clay Working Machinery Company | Tile-press. |
US781882A (en) * | 1904-11-22 | 1905-02-07 | William Hinckle Smith | Compressed product from bone. |
US5246841A (en) | 1986-12-26 | 1993-09-21 | Sagami Chemical Research Center | Microbial process for production of eicosapentaenoic acid |
US5130242A (en) * | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
US5340742A (en) * | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
US5639790A (en) | 1991-05-21 | 1997-06-17 | Calgene, Inc. | Plant medium-chain thioesterases |
US5683898A (en) | 1992-05-15 | 1997-11-04 | Sagami Chemical Research Center | Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid |
US5798259A (en) * | 1992-05-15 | 1998-08-25 | Sagami Chemical Research Center | Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid |
AU673359B2 (en) | 1992-05-15 | 1996-11-07 | Sagami Chemical Research Center | Gene which codes for eicosapentaenoic acid synthetase group and process for producing eicosapentaenoic acid |
US5310242A (en) * | 1992-09-28 | 1994-05-10 | Golder Kimberly A | Portable infant seat |
DE4323727A1 (de) * | 1993-07-15 | 1995-03-09 | Boehringer Mannheim Gmbh | Verfahren zur Identifizierung von menschlichen und tierischen Zellen mit der Fähigkeit zu unbegrenzter Proliferation oder zur Tumorbildung |
US5672491A (en) | 1993-09-20 | 1997-09-30 | The Leland Stanford Junior University | Recombinant production of novel polyketides |
EP0831149A4 (en) | 1995-01-13 | 2000-12-06 | Sagami Chem Res | GENES CODING FOR THE GROUP OF ENZYMES FOR BIOSYNTHESIS OF EICOSAPENTIC ACID AND METHOD FOR PRODUCING EICOSAPENTIC ACID |
WO1996033263A1 (fr) | 1995-04-17 | 1996-10-24 | JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | Nouveaux micro-organismes capables de produire des acides gras hautement insatures et procede de production d'acides gras hautement insatures utilisant ces micro-organismes |
WO1998001565A1 (fr) | 1996-07-10 | 1998-01-15 | Sagami Chemical Research Center | Procede de production d'acide icosapentaenoique par recombinaison genetique |
US6033883A (en) | 1996-12-18 | 2000-03-07 | Kosan Biosciences, Inc. | Production of polyketides in bacteria and yeast |
HUP0001603A3 (en) * | 1997-03-14 | 2004-05-28 | Basf Ag | Cycloalkylalkanecarboxamides and the production and use thereof |
CA2285939C (en) | 1997-04-11 | 2010-06-15 | Calgene Llc | Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants |
US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
BR9809946A (pt) | 1997-06-04 | 2000-08-01 | Calgene Llc | Produção de ácidos graxos poliinsaturados por expressão de genes de sìntese semelhantes a policetìdeo em plantas |
US6626260B2 (en) * | 1998-04-09 | 2003-09-30 | Bombardier Inc. | All terrain vehicle |
US6677145B2 (en) * | 1998-09-02 | 2004-01-13 | Abbott Laboratories | Elongase genes and uses thereof |
US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
US7271315B2 (en) * | 1999-01-14 | 2007-09-18 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US7247461B2 (en) | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
US6246841B1 (en) * | 2000-05-10 | 2001-06-12 | Lexmark International, Inc. | Removable toner cartridge |
AU2001268296B2 (en) | 2000-06-08 | 2006-05-25 | Miami University | Fatty acid elongase 3-ketoacyl coa synthase polypeptides |
US20040010817A1 (en) * | 2000-07-21 | 2004-01-15 | Washington State University Research Foundation | Plant acyl-CoA synthetases |
DE60141760D1 (de) * | 2000-09-28 | 2010-05-20 | Bioriginal Food & Science Corp | Fad4, fad5, fad5-2, and fad6, mitglieder der fettsäuredesaturasefamilie und ihre verwendungen |
TWI350854B (en) * | 2001-04-16 | 2011-10-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
TWI426126B (zh) | 2001-04-16 | 2014-02-11 | Dsm Ip Assets Bv | 多不飽和脂肪酸(pufa)聚乙醯合成酶系統及其用途(二) |
US20040005672A1 (en) | 2002-02-22 | 2004-01-08 | Santi Daniel V. | Heterologous production of polyketides |
GB2385852A (en) * | 2002-02-27 | 2003-09-03 | Rothamsted Ex Station | Delta 6-desaturases from Primulaceae |
US7705202B2 (en) * | 2002-03-16 | 2010-04-27 | The University Of York | Transgenic plants expressing enzymes involved in fatty acid biosynthesis |
US7089432B2 (en) * | 2002-12-27 | 2006-08-08 | Matsushita Electric Industrial Co., Ltd. | Method for operating a processor at first and second rates depending upon whether the processor is executing code to control predetermined hard drive operations |
US20040172682A1 (en) * | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
ES2516641T3 (es) | 2003-03-26 | 2014-10-31 | Dsm Ip Assets B.V. | Sistemas de policétido sintasa de AGPI y usos de los mismos |
EP3121269A1 (de) | 2003-03-31 | 2017-01-25 | University Of Bristol | Neue pflanzliche acyltransferase spezifisch für langkettige mehrfach ungesättigte fettsäuren |
US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
US7208590B2 (en) | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
JP4858818B2 (ja) * | 2004-02-17 | 2012-01-18 | 東レ株式会社 | 二軸配向ポリエステルフィルム |
DE102004060340A1 (de) | 2004-07-16 | 2006-02-09 | Basf Plant Science Gmbh | Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen |
AR050881A1 (es) | 2004-09-20 | 2006-11-29 | Basf Plant Science Gmbh | Genes de arabidopsis que codifican proteinas que participan en el metabolismo de azucares y lipidos y metodos de uso |
KR101524398B1 (ko) * | 2006-03-15 | 2015-06-04 | 디에스엠 아이피 어셋츠 비.브이. | Pufa 폴리케티드 신타제 시스템을 이용한 이종 생물체내 다불포화 지방산의 제조 |
US20080044784A1 (en) * | 2006-08-15 | 2008-02-21 | Park Keith K | Multi-component lighter |
US7669708B2 (en) * | 2006-08-31 | 2010-03-02 | Martin Engineering Company | Bulk material handling system and control |
-
2004
- 2004-10-13 US US10/965,017 patent/US7217856B2/en not_active Expired - Lifetime
-
2005
- 2005-10-13 CN CNA2005800428032A patent/CN101437950A/zh active Pending
- 2005-10-13 MX MX2007004502A patent/MX2007004502A/es not_active Application Discontinuation
- 2005-10-13 BR BRPI0516327-7A patent/BRPI0516327A/pt not_active Application Discontinuation
- 2005-10-13 WO PCT/US2005/036998 patent/WO2006044646A2/en active Application Filing
- 2005-10-13 KR KR1020077010711A patent/KR20070084187A/ko not_active Application Discontinuation
- 2005-10-13 AU AU2005295598A patent/AU2005295598A1/en not_active Abandoned
- 2005-10-13 JP JP2007536936A patent/JP2008515461A/ja active Pending
- 2005-10-13 EP EP05816098A patent/EP1805315A4/en not_active Withdrawn
- 2005-10-13 CA CA002584004A patent/CA2584004A1/en not_active Abandoned
-
2007
- 2007-03-21 US US11/689,459 patent/US7626009B2/en not_active Expired - Fee Related
- 2007-03-21 US US11/689,451 patent/US7601522B2/en not_active Expired - Fee Related
- 2007-03-21 US US11/689,439 patent/US7902427B2/en not_active Expired - Fee Related
- 2007-03-21 US US11/689,453 patent/US7803620B2/en not_active Expired - Fee Related
- 2007-03-21 US US11/689,450 patent/US7906706B2/en not_active Expired - Fee Related
- 2007-03-21 US US11/689,443 patent/US7939716B2/en not_active Expired - Fee Related
- 2007-04-12 IL IL182548A patent/IL182548A0/en unknown
- 2007-07-23 US US11/781,871 patent/US7718431B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,875 patent/US7897392B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,867 patent/US7897391B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,880 patent/US7897393B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,874 patent/US7560539B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,870 patent/US7629450B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,879 patent/US7879608B2/en not_active Expired - Fee Related
- 2007-07-23 US US11/781,877 patent/US7799564B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0516327A (pt) | sistemas de policetìdeo sintase de pufa e usos dos mesmos | |
WO2006135866A3 (en) | Pufa polyketide synthase systems and uses thereof | |
MX2009012395A (es) | Sistema de sintasa de policetida de acido graso poli insaturado (pufa) quimericos y usos de los mismos. | |
AR092778A1 (es) | Produccion de dha (acido docosahexaenoico) y otros acidos grasos poli insaturados de cadena larga en plantas | |
EA201291223A1 (ru) | Получение докогексаеновой кислоты и других длинноцепочечных полиненасыщенных жирных кислот из растений | |
Funck et al. | Aquatic hyphomycetes: a potential source of polyunsaturated fatty acids in detritus-based stream food webs | |
EA200870001A1 (ru) | Гидролизат биомассы, его применение и производство | |
NO20082466L (no) | Delta-9-forlengelser og deres anvendelse ved merking av polyumettede fettsyrer | |
BRPI0910457A2 (pt) | variante de fitase, ácido nucléico, vetor, célula hospedeira, método de produção de uma variante de fitase, composição enzimática, usos, método para a produção de um alimento ou ração para animal e respectivos alimento ou composição de ração para animal e método de redução dos níveis de redução de fósforo em estrume animal | |
AR080353A1 (es) | Plantas tolerantes a herbicidas inhibidores de las hppd | |
AR075897A1 (es) | Moleculas de acido nucleico de sintasa de acido graso poliinsaturado y polipeptidos composiciones y metodos elaboracion y usos de estos. | |
BR112012009668A2 (pt) | proteínas engendradas com dedo de zinco que visam genes vegetais envolvidos na biossíntese de ácidos graxos. | |
BRPI0413786A (pt) | ácido graxo dessaturases de primula | |
CL2009000879A1 (es) | Metodo para fabricar un producto en un biorreactor que comprende cultivar microorganismos que son adaptados o mutagenizados para que exhiban por lo menos un 150% de tolerancia al producto; sistema para fabricar un producto; biorreactor. | |
CL2011002518A1 (es) | Proceso para producir un vegetal, una semilla o su progenie, basado en transformar células vegetales con una secuencia de ácido nucleico que codifica una proteína quinasa relacionada con snf1, vector que comprende dicha secuencia; y métodos de aplicación. | |
ATE493893T1 (de) | Feste enymformulierungen und verfahren zu deren herstellung | |
BRPI0409046A (pt) | sistemas policetìdio sintase (pks) de ácido graxo poliinsaturado (pufa) e usos dos mesmos | |
AR061366A1 (es) | Epsp sintasas mejoradas: composiciones y metodos de uso de las mismas | |
CO6640205A2 (es) | Microorganismos y metodos para la biosintesis de p-toluato y tereftalato | |
UY32994A (es) | Proteínas encapsulantes de lípidos neutros modificadas y sus usos | |
ES2623454T3 (es) | Reducción del contenido de ácidos grasos saturados en semillas de plantas | |
AR036962A1 (es) | Metiltransferasas aromaticas y usos de las mismas | |
WO2007090121A3 (en) | Phosphopantetheinyl transferases from bacteria | |
HN2008001793A (es) | Enzima mdo modificada y metodo para su utilizacion | |
Siódmiak et al. | The High ‘Lipolytic Jump’of Immobilized Amano A Lipase from Aspergillus niger in Developed ‘ESS Catalytic Triangles’ Containing Natural Origin Substrates |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |