BRPI0513943A - uso de um composto ou de um sal farmaceuticamente aceitável - Google Patents

uso de um composto ou de um sal farmaceuticamente aceitável

Info

Publication number
BRPI0513943A
BRPI0513943A BRPI0513943-0A BRPI0513943A BRPI0513943A BR PI0513943 A BRPI0513943 A BR PI0513943A BR PI0513943 A BRPI0513943 A BR PI0513943A BR PI0513943 A BRPI0513943 A BR PI0513943A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
analogues
formulas
Prior art date
Application number
BRPI0513943-0A
Other languages
English (en)
Inventor
Richard Franklin
Original Assignee
Shire Holdings Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Holdings Ag filed Critical Shire Holdings Ag
Publication of BRPI0513943A publication Critical patent/BRPI0513943A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

USO DE UM COMPOSTO OU DE UM SAL FARMACEUTICAMENTE ACEITáVEL De acordo com a presente invenção, é provido um método para tratamento de doença arterial periférica num hospedeiro, compreendendo administrar uma quantidade terapeuticamente eficaz de compostos tendo as fórmulas de (I) a (III) ou análogos dos mesmos.
BRPI0513943-0A 2004-08-04 2005-08-04 uso de um composto ou de um sal farmaceuticamente aceitável BRPI0513943A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59843204P 2004-08-04 2004-08-04
PCT/US2005/028087 WO2006017823A2 (en) 2004-08-04 2005-08-04 Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors

Publications (1)

Publication Number Publication Date
BRPI0513943A true BRPI0513943A (pt) 2008-05-20

Family

ID=35839972

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513943-0A BRPI0513943A (pt) 2004-08-04 2005-08-04 uso de um composto ou de um sal farmaceuticamente aceitável

Country Status (22)

Country Link
US (1) US20060030574A1 (pt)
EP (2) EP1778235A4 (pt)
JP (1) JP4758993B2 (pt)
CN (1) CN101014344A (pt)
AT (1) ATE484278T1 (pt)
AU (1) AU2005271275A1 (pt)
BR (1) BRPI0513943A (pt)
CA (1) CA2575512C (pt)
CY (1) CY1110881T1 (pt)
DE (1) DE602005024192D1 (pt)
DK (1) DK1949893T3 (pt)
EA (1) EA200700406A1 (pt)
ES (1) ES2353848T3 (pt)
HR (1) HRP20100681T1 (pt)
MX (1) MX2007001513A (pt)
NO (1) NO20071098L (pt)
PL (1) PL1949893T3 (pt)
PT (1) PT1949893E (pt)
RS (1) RS51519B (pt)
SI (1) SI1949893T1 (pt)
WO (1) WO2006017823A2 (pt)
ZA (1) ZA200701850B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003509478A (ja) * 1999-09-21 2003-03-11 エモリー・ユニバーシティ 血小板関連障害を処置する方法および組成物
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) * 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
GB0623750D0 (en) * 2006-11-28 2007-01-10 Shire Llc Substituted quinazolines
GB0808947D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808968D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
GB0808967D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines
GB0808952D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines

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Also Published As

Publication number Publication date
EP1949893A2 (en) 2008-07-30
HRP20100681T1 (hr) 2011-01-31
ES2353848T3 (es) 2011-03-07
EP1949893A3 (en) 2008-08-20
JP4758993B2 (ja) 2011-08-31
CY1110881T1 (el) 2015-06-10
ATE484278T1 (de) 2010-10-15
CN101014344A (zh) 2007-08-08
AU2005271275A1 (en) 2006-02-16
PT1949893E (pt) 2011-01-04
EP1778235A2 (en) 2007-05-02
PL1949893T3 (pl) 2011-04-29
RS51519B (en) 2011-06-30
WO2006017823A3 (en) 2006-05-04
ZA200701850B (en) 2008-08-27
DK1949893T3 (da) 2011-01-31
WO2006017823A2 (en) 2006-02-16
EP1778235A4 (en) 2008-08-20
EA200700406A1 (ru) 2007-08-31
MX2007001513A (es) 2007-03-27
NO20071098L (no) 2007-05-03
US20060030574A1 (en) 2006-02-09
JP2008509163A (ja) 2008-03-27
CA2575512A1 (en) 2006-02-16
EP1949893B1 (en) 2010-10-13
DE602005024192D1 (de) 2010-11-25
CA2575512C (en) 2010-12-14
SI1949893T1 (sl) 2011-02-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.