BRPI0510472A - implantes intra-oculares de liberação prolongada antiexcitotóxicos e métodos relacionados - Google Patents
implantes intra-oculares de liberação prolongada antiexcitotóxicos e métodos relacionadosInfo
- Publication number
- BRPI0510472A BRPI0510472A BRPI0510472-6A BRPI0510472A BRPI0510472A BR PI0510472 A BRPI0510472 A BR PI0510472A BR PI0510472 A BRPI0510472 A BR PI0510472A BR PI0510472 A BRPI0510472 A BR PI0510472A
- Authority
- BR
- Brazil
- Prior art keywords
- implants
- related methods
- prolonged release
- eye
- antiexcitotoxic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Abstract
IMPLANTES INTRA-OCULARES DE LIBERAçãO PROLONGADA ANTIEXCITOTóXICOS E MéTODOS RELACIONADOS. A presente invenção refere-se a implantes intra-oculares biocompatíveis que incluem um agente antiexcitotóxico e um polímero que seja eficaz para facilitar a liberação do agente antiexcitotóxico em um olho durante um período de tempo prolongado. Os agentes terapêuticos como antagonistas do receptor de NMDA, como adamantina ou memantina, podem ser associados com um matriz de polímero biodegradável, como uma matriz que seja substancialmente livre de um álcool polivinílico. Os implantes podem ser colocados em um olho para tratar ou reduzir a ocorrência de um ou mais estados oculares, como lesão retiniana, incluindo glaucoma e vitreorretinopatia proliferativa.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/837,142 US20050244478A1 (en) | 2004-04-30 | 2004-04-30 | Anti-excititoxic sustained release intraocular implants and related methods |
PCT/US2005/015034 WO2005107718A1 (en) | 2004-04-30 | 2005-04-28 | Anti-excitotoxic sustained release intraocular implants and related methods |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0510472A true BRPI0510472A (pt) | 2007-11-06 |
Family
ID=34968326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0510472-6A BRPI0510472A (pt) | 2004-04-30 | 2005-04-28 | implantes intra-oculares de liberação prolongada antiexcitotóxicos e métodos relacionados |
Country Status (11)
Country | Link |
---|---|
US (6) | US20050244478A1 (pt) |
EP (1) | EP1740157A1 (pt) |
JP (1) | JP2007535564A (pt) |
KR (1) | KR20070004927A (pt) |
CN (1) | CN1950069A (pt) |
AU (2) | AU2005240081C1 (pt) |
BR (1) | BRPI0510472A (pt) |
CA (1) | CA2565459A1 (pt) |
MX (1) | MXPA06012287A (pt) |
TW (1) | TW200603775A (pt) |
WO (1) | WO2005107718A1 (pt) |
Families Citing this family (25)
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AU2005209201B2 (en) | 2004-01-20 | 2010-06-03 | Allergan, Inc. | Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid |
US8119154B2 (en) | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
US8673341B2 (en) | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
US8147865B2 (en) | 2004-04-30 | 2012-04-03 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
US20080033053A1 (en) * | 2004-07-22 | 2008-02-07 | Wolfgang Curt D | Cross-Reference To Related Applications |
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US8142388B2 (en) * | 2006-10-30 | 2012-03-27 | Gomez Mario P | Apparatus to facilitate removal of cataracts of from the eyes |
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WO2008098027A2 (en) * | 2007-02-06 | 2008-08-14 | Allergan, Inc. | Treatment of ischemic retinal conditions with memantine |
US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
JP5591226B2 (ja) | 2008-05-12 | 2014-09-17 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 眼内薬物送達装置および関連する方法 |
US9095404B2 (en) | 2008-05-12 | 2015-08-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
US8349005B2 (en) | 2011-01-03 | 2013-01-08 | Masatoshi Murata | Method for burying implant to choroid |
WO2017093354A1 (en) * | 2015-11-30 | 2017-06-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Nmdar antagonists for the treatment of diseases associated with angiogenesis |
EP3897575A1 (en) * | 2018-12-21 | 2021-10-27 | Re-Vana Therapeutics Ltd | Coated ocular implants |
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-
2004
- 2004-04-30 US US10/837,142 patent/US20050244478A1/en not_active Abandoned
-
2005
- 2005-04-28 BR BRPI0510472-6A patent/BRPI0510472A/pt not_active IP Right Cessation
- 2005-04-28 KR KR1020067022641A patent/KR20070004927A/ko not_active Application Discontinuation
- 2005-04-28 JP JP2007511059A patent/JP2007535564A/ja active Pending
- 2005-04-28 CN CNA2005800135756A patent/CN1950069A/zh active Pending
- 2005-04-28 AU AU2005240081A patent/AU2005240081C1/en not_active Ceased
- 2005-04-28 EP EP05744059A patent/EP1740157A1/en not_active Withdrawn
- 2005-04-28 WO PCT/US2005/015034 patent/WO2005107718A1/en not_active Application Discontinuation
- 2005-04-28 CA CA002565459A patent/CA2565459A1/en not_active Abandoned
- 2005-04-28 MX MXPA06012287A patent/MXPA06012287A/es not_active Application Discontinuation
- 2005-04-29 TW TW094113963A patent/TW200603775A/zh unknown
- 2005-04-29 US US11/117,879 patent/US20050244473A1/en not_active Abandoned
-
2007
- 2007-02-28 US US11/680,613 patent/US20070141117A1/en not_active Abandoned
- 2007-02-28 US US11/680,615 patent/US20070148208A1/en not_active Abandoned
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2008
- 2008-04-17 US US12/105,232 patent/US20080193502A1/en not_active Abandoned
- 2008-04-17 US US12/105,233 patent/US20080193503A1/en not_active Abandoned
-
2010
- 2010-09-23 AU AU2010224394A patent/AU2010224394A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20070148208A1 (en) | 2007-06-28 |
US20070141117A1 (en) | 2007-06-21 |
US20080193503A1 (en) | 2008-08-14 |
JP2007535564A (ja) | 2007-12-06 |
CA2565459A1 (en) | 2005-11-17 |
EP1740157A1 (en) | 2007-01-10 |
KR20070004927A (ko) | 2007-01-09 |
US20050244478A1 (en) | 2005-11-03 |
TW200603775A (en) | 2006-02-01 |
AU2010224394A1 (en) | 2010-10-14 |
US20050244473A1 (en) | 2005-11-03 |
AU2005240081A1 (en) | 2005-11-17 |
WO2005107718A1 (en) | 2005-11-17 |
US20080193502A1 (en) | 2008-08-14 |
AU2005240081B2 (en) | 2010-06-24 |
MXPA06012287A (es) | 2006-12-15 |
CN1950069A (zh) | 2007-04-18 |
AU2005240081C1 (en) | 2011-02-10 |
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