BRPI0509897A - aparelho e método para distribuição transdérmica de múltiplas vacinas - Google Patents
aparelho e método para distribuição transdérmica de múltiplas vacinasInfo
- Publication number
- BRPI0509897A BRPI0509897A BRPI0509897-1A BRPI0509897A BRPI0509897A BR PI0509897 A BRPI0509897 A BR PI0509897A BR PI0509897 A BRPI0509897 A BR PI0509897A BR PI0509897 A BRPI0509897 A BR PI0509897A
- Authority
- BR
- Brazil
- Prior art keywords
- array
- active agent
- immunologically active
- regions
- biocompatible coating
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000037317 transdermal delivery Effects 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 4
- 238000000576 coating method Methods 0.000 abstract 4
- 239000011248 coating agent Substances 0.000 abstract 3
- 239000002671 adjuvant Substances 0.000 abstract 1
- 210000004207 dermis Anatomy 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 210000000434 stratum corneum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
APARELHO E MéTODO PARA DISTRIBUIçãO TRANSDéRMICA DE MúLTIPLAS VACINAS. a presente invenção refere-se a um aparelho e método para a distribuição transdérmica de um agente imunologicamente ativo compreendendo um sistema de distribuição possuindo um conjunto de microprojeções que inclui uma pluraridade de microprojeções que são adaptadas para perfurar o stratum corneum e entrar na camada epidérmica subjacente,ou as camadas de ipiderme e derme, o conjunto de microprojeção uma pluraridade de regiões de conjunto, cada uma das regiões de conjunto, cada uma das regiões de conjunto posuindo um revesimento biocompatível diferente na mesma,onde pelo menos um dos revestimentos de região de conjunto iclui um agente imunologicamente ativo. Em uma modalidade, cada revestimento nas regiões de conjunto inclui um agente imunologicamente ativo diferente. Em outra modalidade,o revestimento biocompatível em uma primeira região de conjunto inclui um agente imunologicamente ativo e o revestimento biocompatível em uma segunda região de conjunto inclui um adjuvante de aumento de resposta imune.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56195304P | 2004-04-13 | 2004-04-13 | |
PCT/US2005/009152 WO2005103303A2 (en) | 2004-04-13 | 2005-03-18 | Apparatus and method for transdermal delivery of multiple vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0509897A true BRPI0509897A (pt) | 2007-08-07 |
Family
ID=35197563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509897-1A BRPI0509897A (pt) | 2004-04-13 | 2005-03-18 | aparelho e método para distribuição transdérmica de múltiplas vacinas |
Country Status (12)
Country | Link |
---|---|
US (1) | US20050271684A1 (pt) |
EP (1) | EP1735469A2 (pt) |
JP (1) | JP2007537783A (pt) |
KR (1) | KR20070011481A (pt) |
CN (1) | CN101120101A (pt) |
AR (1) | AR048545A1 (pt) |
AU (1) | AU2005235990A1 (pt) |
BR (1) | BRPI0509897A (pt) |
CA (1) | CA2562642A1 (pt) |
MX (1) | MXPA06011971A (pt) |
TW (1) | TW200600107A (pt) |
WO (1) | WO2005103303A2 (pt) |
Families Citing this family (31)
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US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
JP2008507590A (ja) * | 2004-05-19 | 2008-03-13 | アルザ コーポレイション | 免疫活性剤を経皮送達するための方法及び配合物 |
US20070299388A1 (en) * | 2006-04-25 | 2007-12-27 | Alza Corporation | Microprojection array application with multilayered microprojection member for high drug loading |
EP2146689B1 (en) | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
DE102007060599A1 (de) * | 2007-12-15 | 2009-06-18 | Merck Patent Gmbh | Verfahren zur Extraktion von Membranproteinen |
MX2011003277A (es) * | 2008-10-14 | 2012-09-21 | Salubrious Pharmaceuticals LLC | Proceso para el tratamiento de la artritis reumatoide, temblores/enfermedad de parkinson, esclerosis multiple y cancer de tipo no viral. |
US20110196299A1 (en) * | 2008-10-25 | 2011-08-11 | Youn-Sung Kim | Structure of needle for syringe |
CN102281897A (zh) * | 2008-10-31 | 2011-12-14 | T·S·顾巴 | 通过机械破坏表皮进行痘病毒载体的疫苗接种 |
US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
US20110006458A1 (en) * | 2009-04-24 | 2011-01-13 | Corium International, Inc. | Methods for manufacturing microprojection arrays |
WO2010127144A1 (en) | 2009-04-29 | 2010-11-04 | Muniyappa Pravin K | Device and method for the diagnosis of gastrointestinal allergy |
CA2798145C (en) | 2010-05-04 | 2022-10-18 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
JP5225364B2 (ja) | 2010-12-08 | 2013-07-03 | 住友ゴム工業株式会社 | ストリップ、その製造方法および空気入りタイヤの製造方法 |
WO2012151272A2 (en) * | 2011-05-02 | 2012-11-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
WO2014100750A1 (en) | 2012-12-21 | 2014-06-26 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
JPWO2014142135A1 (ja) | 2013-03-12 | 2017-02-16 | 武田薬品工業株式会社 | マイクロニードルパッチ |
BR122020006959B1 (pt) | 2013-03-12 | 2022-04-26 | Corium, Inc | Aplicador de microprojeções |
JP6700170B2 (ja) | 2013-03-15 | 2020-05-27 | コリウム, インコーポレイテッド | 治療剤の送達のためのマイクロアレイおよび使用の方法 |
US10384045B2 (en) | 2013-03-15 | 2019-08-20 | Corium, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
CN106061546A (zh) * | 2014-02-10 | 2016-10-26 | Lts勒曼治疗***股份公司 | 微针***及其制造方法 |
WO2016036866A1 (en) | 2014-09-04 | 2016-03-10 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
JP6724792B2 (ja) * | 2015-01-13 | 2020-07-15 | 凸版印刷株式会社 | 経皮投与デバイス |
WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
JP7217700B2 (ja) | 2016-09-13 | 2023-02-03 | アラーガン、インコーポレイテッド | 安定化非タンパク質クロストリジウム毒素組成物 |
US11241563B2 (en) * | 2016-12-22 | 2022-02-08 | Johnson & Johnson Consumer Inc. | Microneedle arrays and methods for making and using |
CN110831625A (zh) * | 2017-07-24 | 2020-02-21 | 株式会社培旺精廉宅 | 疫苗佐剂及微针制剂 |
WO2019190267A1 (ko) * | 2018-03-30 | 2019-10-03 | 랩앤피플주식회사 | 멀티형 마이크로 니들 |
KR20210025601A (ko) | 2018-06-29 | 2021-03-09 | 존슨 앤드 존슨 컨수머 인코포레이티드 | 활성제의 전달을 위한 3차원 미세유체학 장치 |
US11697009B2 (en) * | 2019-09-06 | 2023-07-11 | Industry-Academic Cooperation Foundation, Yonsei University | Microneedle patch, micro needle system and method of fabricating the same |
US11796548B2 (en) | 2020-04-22 | 2023-10-24 | The United States Of America, As Represented By The Secretary Of Agriculture | Continuous stable cell line for identification of infectious African swine fever virus in clinical samples |
CN115068602B (zh) * | 2022-08-22 | 2022-11-01 | 北京华诺泰生物医药科技有限公司 | 一种表面改性氧化铝的复合疫苗佐剂、制备方法及应用 |
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AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
US20040265365A1 (en) * | 2003-06-30 | 2004-12-30 | Daddona Peter E. | Method for coating skin piercing microprojections |
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US20050106227A1 (en) * | 2003-10-28 | 2005-05-19 | Samuel Zalipsky | Delivery of polymer conjugates of therapeutic peptides and proteins via coated microprojections |
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WO2005051456A2 (en) * | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
BRPI0509493A (pt) * | 2004-04-01 | 2007-09-11 | Alza Corp | aparelho e método para a liberação transdérmica de vacina da influenza |
AU2005244734A1 (en) * | 2004-05-13 | 2005-12-01 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
-
2005
- 2005-03-18 AU AU2005235990A patent/AU2005235990A1/en not_active Abandoned
- 2005-03-18 KR KR1020067023637A patent/KR20070011481A/ko not_active Application Discontinuation
- 2005-03-18 BR BRPI0509897-1A patent/BRPI0509897A/pt not_active Application Discontinuation
- 2005-03-18 MX MXPA06011971A patent/MXPA06011971A/es unknown
- 2005-03-18 EP EP05725915A patent/EP1735469A2/en not_active Withdrawn
- 2005-03-18 CN CNA2005800191879A patent/CN101120101A/zh active Pending
- 2005-03-18 CA CA002562642A patent/CA2562642A1/en not_active Abandoned
- 2005-03-18 WO PCT/US2005/009152 patent/WO2005103303A2/en active Application Filing
- 2005-03-18 JP JP2007508359A patent/JP2007537783A/ja active Pending
- 2005-03-18 US US11/084,635 patent/US20050271684A1/en not_active Abandoned
- 2005-04-12 TW TW094111542A patent/TW200600107A/zh unknown
- 2005-04-13 AR ARP050101445A patent/AR048545A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005103303A3 (en) | 2007-10-18 |
MXPA06011971A (es) | 2007-04-16 |
AR048545A1 (es) | 2006-05-03 |
AU2005235990A1 (en) | 2005-11-03 |
CA2562642A1 (en) | 2005-11-03 |
KR20070011481A (ko) | 2007-01-24 |
US20050271684A1 (en) | 2005-12-08 |
JP2007537783A (ja) | 2007-12-27 |
EP1735469A2 (en) | 2006-12-27 |
TW200600107A (en) | 2006-01-01 |
WO2005103303A2 (en) | 2005-11-03 |
CN101120101A (zh) | 2008-02-06 |
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Legal Events
Date | Code | Title | Description |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |