BRPI0507294A - processo de fabricação de um gel reticulado biocompátivel, gel, e, utilização do gel - Google Patents
processo de fabricação de um gel reticulado biocompátivel, gel, e, utilização do gelInfo
- Publication number
- BRPI0507294A BRPI0507294A BRPI0507294-8A BRPI0507294A BRPI0507294A BR PI0507294 A BRPI0507294 A BR PI0507294A BR PI0507294 A BRPI0507294 A BR PI0507294A BR PI0507294 A BRPI0507294 A BR PI0507294A
- Authority
- BR
- Brazil
- Prior art keywords
- gel
- crosslinking
- manufacturing process
- solution
- polymer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
- C08J3/245—Differential crosslinking of one polymer with one crosslinking type, e.g. surface crosslinking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCESSO DE FABRICAçãO DE UM GEL RETICULADO BIOCOMPATìVEL,GEL,E,UTILIZAçãO DO GEL A invenção refere-se a um processo de fabricação de um gel reticulado biocompatível que envolve as etapas: de iniciação da reticulação de uma quantidade determinada de pelo menos um polímero biocompatível em solução por adição de uma quantidade de agente reticulante, de reação de reticulação da dita quantidade de polímero, de adição de uma quantidade suplementar de polímero de massa molecular superior a 500 000 Da em solução com diluição da mistura da reação de maneira a diminuir a concentração global do polímero em solução e de reticulação e de interrupção da reação de reticulação por eliminação do agente reticulante; assim como o dito gel e utilização do mesmo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0400987 | 2004-02-03 | ||
FR0400987A FR2865737B1 (fr) | 2004-02-03 | 2004-02-03 | Gel reticule biocompatible |
PCT/FR2005/000197 WO2005085329A1 (fr) | 2004-02-03 | 2005-01-31 | Gel reticule biocompatible |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0507294A true BRPI0507294A (pt) | 2007-07-03 |
BRPI0507294B1 BRPI0507294B1 (pt) | 2019-02-19 |
BRPI0507294B8 BRPI0507294B8 (pt) | 2021-07-27 |
Family
ID=34746373
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0507294A BRPI0507294B8 (pt) | 2004-02-03 | 2005-01-31 | processo de fabricação de um gel reticulado biocompatível, gel, e, utilização do gel |
Country Status (15)
Country | Link |
---|---|
US (1) | US8052990B2 (pt) |
EP (1) | EP1711552B1 (pt) |
JP (1) | JP5105274B2 (pt) |
KR (1) | KR101044339B1 (pt) |
CN (1) | CN100582146C (pt) |
AT (1) | ATE489420T1 (pt) |
AU (1) | AU2005219595B2 (pt) |
BR (1) | BRPI0507294B8 (pt) |
CA (1) | CA2554597C (pt) |
DE (1) | DE602005024919D1 (pt) |
ES (1) | ES2354699T3 (pt) |
FR (1) | FR2865737B1 (pt) |
PL (1) | PL1711552T3 (pt) |
RU (1) | RU2377260C2 (pt) |
WO (1) | WO2005085329A1 (pt) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2377479T3 (es) * | 2005-09-27 | 2012-03-28 | Universite Joseph Fourier - Grenoble 1 | Hidrogel funcionalizado con una porción polimerizable y sus utilizaciones como biosensores o biorreactores. |
WO2008034176A1 (en) * | 2006-09-19 | 2008-03-27 | Ultraceuticals R & D Pty Ltd | Cross-linked polysaccharide gels |
FR2909285A1 (fr) * | 2006-12-01 | 2008-06-06 | Anteis Sa | "utilisation d'un gel anti-adhesif et anti fibrotique" |
FR2909560B1 (fr) | 2006-12-06 | 2012-12-28 | Fabre Pierre Dermo Cosmetique | Gel d'acide hyaluronique pour injection intradermique |
US20080287633A1 (en) * | 2007-05-18 | 2008-11-20 | Drumheller Paul D | Hydrogel Materials |
FR2918276B1 (fr) * | 2007-07-02 | 2010-01-22 | Anteis Sa | "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires" |
FR2918377B1 (fr) | 2007-07-05 | 2010-10-08 | Estelle Piron | Gel co-reticule de polysaccharides |
WO2009021526A1 (de) * | 2007-07-25 | 2009-02-19 | S & V Technologies Ag | Hyaluronsäuredispersion, herstellung und anwendung |
HUE042931T2 (hu) | 2007-11-16 | 2019-07-29 | Aclaris Therapeutics Inc | Kompozíciók és eljárások purpura kezelésére |
US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
FR2924615B1 (fr) * | 2007-12-07 | 2010-01-22 | Vivacy Lab | Hydrogel cohesif biodegradable. |
FR2927255B1 (fr) * | 2008-02-07 | 2011-08-12 | Keysan Consulting | Produits injectables biocompatibles a liberation de zinc et/ou de sel de saccharide sous forme de zinc et leurs utilisations. |
JP5574083B2 (ja) * | 2008-08-01 | 2014-08-20 | アンタイス エス.エイ. | 高い残留性及び容量を与える高い能力を有する注入可能なヒドロゲル |
US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
AU2009288118B2 (en) | 2008-09-02 | 2014-12-11 | Allergan, Inc. | Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
US9339514B2 (en) | 2008-09-12 | 2016-05-17 | Aptissen Sa | Method for treating glaucoma |
US8715266B2 (en) * | 2008-09-12 | 2014-05-06 | Aptissen Sa | Glaucoma surgery |
FR2938187B1 (fr) | 2008-11-07 | 2012-08-17 | Anteis Sa | Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur |
FR2945293B1 (fr) * | 2009-05-11 | 2011-06-17 | Teoxane | Procede de preparation d'un gel reticule. |
US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
FR2957254B1 (fr) | 2010-03-12 | 2016-10-14 | Allergan Ind Sas | Compositions fluides pour ameliorer les etats de la peau |
US8691279B2 (en) | 2010-03-22 | 2014-04-08 | Allergan, Inc. | Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation |
FR2962040B3 (fr) * | 2010-07-05 | 2012-08-10 | Alain Villette | Composition injectable comprenant un medicament injectable et un gel |
US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
FR2968305B1 (fr) | 2010-12-06 | 2014-02-28 | Teoxane | Procede de preparation d'un gel reticule |
FR2968996B1 (fr) | 2010-12-17 | 2013-04-12 | Anteis Sa | Formulation aqueuse injectable sterile utilisee en ophtalmologie |
WO2012143876A1 (en) | 2011-04-19 | 2012-10-26 | Anteis S.A. | A sterile and injectable aqueous formulation for administration in the intra-articular space of an intra-articular joint |
JP6009550B2 (ja) | 2011-06-03 | 2016-10-19 | アラーガン、インコーポレイテッドAllergan,Incorporated | 抗酸化物質を含む皮膚充填剤組成物 |
US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
KR20210125119A (ko) * | 2011-09-14 | 2021-10-15 | 알러간, 인코포레이티드 | 잔주름 치료를 위한 진피 필러 조성물 |
ITAN20110138A1 (it) | 2011-10-12 | 2012-01-11 | Regenyal Lab S R L | Sintesi di un gel iniettabile multifasico a base di acido ialuronico monofasico libero e reticolato e di acido ialuronico bifasico associato con idrossiapatite con inibitore della ialuronidasi microincapsulato. |
ITMI20120732A1 (it) | 2012-05-03 | 2013-11-04 | B S Srl | Polisaccaridi reticolati a memoria di forma |
FR2991876B1 (fr) | 2012-06-13 | 2014-11-21 | Vivacy Lab | Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate |
IN2014DN10147A (pt) | 2012-06-15 | 2015-08-21 | Merz Pharma Gmbh & Co Kgaa | |
US20140315828A1 (en) | 2013-04-22 | 2014-10-23 | Allergan, Inc. | Cross-linked silk-hyaluronic acid compositions |
FR3006689A1 (fr) | 2013-06-11 | 2014-12-12 | Benedicte Vincente Tauzin | Procede de reticulation de l'acide hyaluronique; procede de preparation d'un hydrogel injectable; hydrogel obtenu; utilisation de l'hydroget obtenu |
WO2014198406A1 (en) | 2013-06-11 | 2014-12-18 | Anteis S.A. | Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel |
CN110003360A (zh) * | 2013-06-28 | 2019-07-12 | 盖尔德玛公司 | 用于制备交联的透明质酸产物的方法 |
US10272181B2 (en) | 2013-09-27 | 2019-04-30 | Anteis S.A. | Method for obtaining an injectable hydrogel based on hyaluronic acid containing lidocaine and an alkaline agent, sterilized with heat |
AR099900A1 (es) | 2014-04-01 | 2016-08-24 | Merz Pharma Gmbh & Co Kgaa | Rellenos para tejidos blandos con polisacáridos con persistencia mejorada, kit, procedimiento, uso |
US10722444B2 (en) | 2014-09-30 | 2020-07-28 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
FR3029928B1 (fr) | 2014-12-15 | 2018-03-09 | Teoxane | Gel reticule |
FR3037797B1 (fr) | 2015-06-24 | 2018-08-17 | Kylane Laboratoires Sa | Procede de preparation d'un hydrogel reticule injectable; hydrogel obtenu; utilisation de l'hydrogel obtenu |
WO2017001057A1 (en) | 2015-06-30 | 2017-01-05 | Merz Pharma Gmbh & Co. Kgaa | Method of preparing a composition based on hyaluronic acid |
US10836840B2 (en) * | 2015-06-30 | 2020-11-17 | Merz Pharma Gmbh & Co. Kgaa | Method for producing crosslinked hyaluronic acid |
DE102015009271A1 (de) * | 2015-07-19 | 2017-01-19 | Tracey Lennemann | Neue Verwendung von Hyaluronsäure |
US20190000874A1 (en) * | 2015-08-13 | 2019-01-03 | Newven Sprl | Composition for the Treatment of Joint Conditions |
LT3347061T (lt) * | 2015-09-09 | 2021-09-10 | ETH Zürich | Įšvirkščiami makroporiniai hidrogeliai |
EP3162813A1 (en) | 2015-11-02 | 2017-05-03 | Merz Pharma GmbH & Co. KGaA | Process for depleting epoxide species in crosslinked poly-saccharide gel compositions and compositions obtained thereby |
KR20170060599A (ko) | 2015-11-24 | 2017-06-01 | (주)한국비엠아이 | 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 |
FR3044557B1 (fr) | 2015-12-07 | 2017-12-01 | Benedicte Vincente Gavard Molliard Tauzin | Nouvelle composition injectable; procede de preparation de ladite composition; utilisation de ladite composition |
FR3047666A1 (fr) | 2016-02-15 | 2017-08-18 | Benedicte Vincente Gavard Molliard Tauzin | Composition injectable; procede de preparation de ladite composition; utilisation de ladite composition |
TWI727014B (zh) | 2016-03-24 | 2021-05-11 | 德商梅茲製藥有限兩合公司 | 修飾透明質酸與其製造方法及其用途 |
CA2961868A1 (en) * | 2016-04-08 | 2017-10-08 | Johnson & Johnson Consumer Inc. | Topical compositions containing cross-linked glycosaminoglycans |
EP3503841A4 (en) | 2016-08-24 | 2020-04-22 | Allergan, Inc. | CO-CROSSLINKED HYALURONIC ACID-FIBROIN HYDROGELS FOR IMPROVING THE SUSTAINABILITY OF TISSUE GRAFTS AND FOR INCREASING SOFT TISSUES |
CN106397795B (zh) * | 2016-08-31 | 2018-12-21 | 陕西佰傲再生医学有限公司 | 一种混合透明质酸凝胶及其制备方法 |
EP3535031B1 (en) | 2016-11-03 | 2024-04-10 | Merz Pharma GmbH & Co. KGaA | Method for preparing hyaluronic acid dermal fillers, dermal fillers obtained thereby and their use |
EP3538066B1 (en) | 2016-11-11 | 2021-12-29 | Anteis SA | Hyaluronic acid dermal fillers crosslinked with citric acid, method for making same and uses thereof |
WO2018220283A1 (fr) | 2017-05-29 | 2018-12-06 | Kh Medtech Sarl | Composition injectable sterile contenant de l'acide hyaluronique reticule et de l'articaine |
WO2019121688A1 (en) | 2017-12-22 | 2019-06-27 | Nestlé Skin Health Sa | Injectable gel product |
EP3743079A1 (en) * | 2018-02-06 | 2020-12-02 | Regen Lab SA | Cross-linked hyaluronic acids and combinations with prp/bmc |
US20190240335A1 (en) * | 2018-02-07 | 2019-08-08 | Promedon S.A. | Biocompatible Hydrogel Compositions |
WO2020030629A1 (en) | 2018-08-07 | 2020-02-13 | Merz Pharma Gmbh & Co. Kgaa | Method for dynamic filtration of a cross-linked hydrogel |
LU101045B1 (en) | 2018-12-11 | 2020-06-11 | Qventis GmbH | Method for the manufacture and use of a bionic hydrogel composition for medical applications |
WO2021116069A1 (en) | 2019-12-09 | 2021-06-17 | Merz Pharma Gmbh & Co. Kgaa | Process for producing a composition comprising a crosslinked hydrogel |
WO2023275278A1 (en) | 2021-06-30 | 2023-01-05 | Merz Pharma Gmbh & Co. Kgaa | Hyaluronic acid dermal fillers crosslinked with polyethylene glycol diglycidyl ether, method for making same and uses thereof |
CN114470333B (zh) * | 2022-03-09 | 2023-05-23 | 哈尔滨敷尔佳科技股份有限公司 | 交联重组胶原蛋白凝胶的制备方法 |
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JPS5951789A (ja) * | 1982-09-18 | 1984-03-26 | Wako Pure Chem Ind Ltd | 安定化酵素 |
US4716224A (en) * | 1984-05-04 | 1987-12-29 | Seikagaku Kogyo Co. Ltd. | Crosslinked hyaluronic acid and its use |
US6174999B1 (en) * | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
ES2153378T3 (es) * | 1992-02-28 | 2001-03-01 | Univ Texas | Hidrogeles biodegradables fotopolimerizables como materiales de contacto de tejidos y portadores de descarga controlada. |
HUT71776A (en) * | 1994-03-21 | 1996-01-29 | Ciba Geigy Ag | Antibody conjugates with improved properties |
EP0713707A1 (en) * | 1994-11-23 | 1996-05-29 | Collagen Corporation | In situ crosslinkable, injectable collagen composition for tissue augmention |
FR2733426B1 (fr) * | 1995-04-25 | 1997-07-18 | Debacker Yves | Dispositif medical pour le comblement des deformations du volume de la peau telles que rides et cicatrices par injection de 2 formes physico-chimiques differentes d'un polymere biologique |
US5827937A (en) * | 1995-07-17 | 1998-10-27 | Q Med Ab | Polysaccharide gel composition |
GB9902652D0 (en) * | 1999-02-05 | 1999-03-31 | Fermentech Med Ltd | Process |
FR2811996B1 (fr) | 2000-07-19 | 2003-08-08 | Corneal Ind | Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations |
AU2002230102B9 (en) * | 2001-01-31 | 2008-05-01 | Seikagaku Corporation | Crosslinked polysaccharide sponge |
DE60323943D1 (de) * | 2002-02-21 | 2008-11-20 | Encelle Inc | Immobilisierte bioaktive hydrogel matrizen für oberflächenbeschichtungen |
JP4958368B2 (ja) * | 2002-02-28 | 2012-06-20 | 電気化学工業株式会社 | 架橋ヒアルロン酸 |
-
2004
- 2004-02-03 FR FR0400987A patent/FR2865737B1/fr not_active Expired - Fee Related
-
2005
- 2005-01-31 KR KR1020067015505A patent/KR101044339B1/ko active IP Right Grant
- 2005-01-31 ES ES05717516T patent/ES2354699T3/es active Active
- 2005-01-31 JP JP2006551875A patent/JP5105274B2/ja active Active
- 2005-01-31 US US10/588,186 patent/US8052990B2/en active Active
- 2005-01-31 CA CA2554597A patent/CA2554597C/fr active Active
- 2005-01-31 RU RU2006127591/04A patent/RU2377260C2/ru active
- 2005-01-31 BR BRPI0507294A patent/BRPI0507294B8/pt active IP Right Grant
- 2005-01-31 CN CN200580003963A patent/CN100582146C/zh active Active
- 2005-01-31 PL PL05717516T patent/PL1711552T3/pl unknown
- 2005-01-31 DE DE602005024919T patent/DE602005024919D1/de active Active
- 2005-01-31 AU AU2005219595A patent/AU2005219595B2/en active Active
- 2005-01-31 AT AT05717516T patent/ATE489420T1/de active
- 2005-01-31 EP EP05717516A patent/EP1711552B1/fr active Active
- 2005-01-31 WO PCT/FR2005/000197 patent/WO2005085329A1/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FR2865737B1 (fr) | 2006-03-31 |
AU2005219595A1 (en) | 2005-09-15 |
CN100582146C (zh) | 2010-01-20 |
US8052990B2 (en) | 2011-11-08 |
PL1711552T3 (pl) | 2011-04-29 |
KR101044339B1 (ko) | 2011-06-29 |
WO2005085329A1 (fr) | 2005-09-15 |
AU2005219595B2 (en) | 2010-07-29 |
JP2007520612A (ja) | 2007-07-26 |
DE602005024919D1 (de) | 2011-01-05 |
FR2865737A1 (fr) | 2005-08-05 |
CA2554597C (fr) | 2012-04-24 |
ES2354699T3 (es) | 2011-03-17 |
EP1711552A1 (fr) | 2006-10-18 |
KR20070004611A (ko) | 2007-01-09 |
EP1711552B1 (fr) | 2010-11-24 |
ATE489420T1 (de) | 2010-12-15 |
CA2554597A1 (fr) | 2005-09-15 |
RU2006127591A (ru) | 2008-02-10 |
US20070196426A1 (en) | 2007-08-23 |
JP5105274B2 (ja) | 2012-12-26 |
CN1918219A (zh) | 2007-02-21 |
RU2377260C2 (ru) | 2009-12-27 |
BRPI0507294B1 (pt) | 2019-02-19 |
BRPI0507294B8 (pt) | 2021-07-27 |
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