BRPI0507187A - composições para tratamento bucal compreendendo teores biodisponìveis mais altos de compostos antimicrobianos à base de amÈnio quaternário - Google Patents

composições para tratamento bucal compreendendo teores biodisponìveis mais altos de compostos antimicrobianos à base de amÈnio quaternário

Info

Publication number
BRPI0507187A
BRPI0507187A BRPI0507187-9A BRPI0507187A BRPI0507187A BR PI0507187 A BRPI0507187 A BR PI0507187A BR PI0507187 A BRPI0507187 A BR PI0507187A BR PI0507187 A BRPI0507187 A BR PI0507187A
Authority
BR
Brazil
Prior art keywords
quaternary ammonium
compositions
contents
compounds
formulated
Prior art date
Application number
BRPI0507187-9A
Other languages
English (en)
Inventor
Rebecca Lynn Roberge
Andrew Lee Wong
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BRPI0507187A publication Critical patent/BRPI0507187A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPOSIçõES PARA TRATAMENTO BUCAL COMPREENDENDO TEORES BIODISPONìVEIS MAIS ALTOS DE COMPOSTOS ANTIMICROBIANOS à BASE DE AMÈNIO QUATERNáRIO. A presente invenção refere-se a composições para tratamento bucal, inclusive enxágües terapêuticos e, especialmente, enxaguatórios bucais, bem como métodos de uso para a obtenção de atividade antimicrobiana significativamente acentuada, reduzindo a presença de bactérias na cavidade oral e promovendo a saúde bucal geral. As presentes composições são formuladas de modo a fornecer teores biodisponíveis elevados de compostos antimicrobianos catiónicos, particularmente compostos de amónio quaternário como cloreto de cetilpiridínio (CPC), e são úteis na prevenção e no tratamento de doenças ou problemas de saúde da cavidade bucal, inclusive placa dental, cárie, gengivite, doença periodontal e hálito com odor desagradável. As presentes composições são formuladas para serem essencialmente isentas de tensoativos aniónicos, não-iónicos ou anfotéricos que, segundo o que se descobriu, têm um efeito negativo sobre a biodisponibilidade dos compostos de amónio quaternário e, portanto, sobre sua eficácia antimicrobiana.
BRPI0507187-9A 2004-01-29 2005-01-27 composições para tratamento bucal compreendendo teores biodisponìveis mais altos de compostos antimicrobianos à base de amÈnio quaternário BRPI0507187A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54094904P 2004-01-29 2004-01-29
PCT/US2005/002917 WO2005072693A1 (en) 2004-01-29 2005-01-27 Oral care compositions comprising increased bioavailable levels of quaternary ammonium antimicrobials

Publications (1)

Publication Number Publication Date
BRPI0507187A true BRPI0507187A (pt) 2007-06-26

Family

ID=34826246

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507187-9A BRPI0507187A (pt) 2004-01-29 2005-01-27 composições para tratamento bucal compreendendo teores biodisponìveis mais altos de compostos antimicrobianos à base de amÈnio quaternário

Country Status (11)

Country Link
US (1) US9241885B2 (pt)
EP (1) EP1708791B1 (pt)
JP (1) JP2007518828A (pt)
CN (1) CN1909875B (pt)
BR (1) BRPI0507187A (pt)
CA (2) CA2774961C (pt)
ES (1) ES2606336T3 (pt)
MX (1) MXPA06008604A (pt)
PL (1) PL1708791T3 (pt)
RU (1) RU2325899C2 (pt)
WO (1) WO2005072693A1 (pt)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050100601A1 (en) * 2003-11-07 2005-05-12 Viratox, L.L.C. Virucidal activities of cetylpyridinium chloride
US20090232748A1 (en) * 2003-11-07 2009-09-17 Viratox, L.L.C. Virucidal activities of cetylpyridinium chloride
US9968526B1 (en) 2005-01-24 2018-05-15 Dental Alliance Holdings, Lll System for caries management by risk assessment
US8496914B2 (en) 2005-12-13 2013-07-30 Richard Paul Bonfiglio Antibacterial oral rinse formulation for preventing coronary artery disease
US9427384B2 (en) 2006-01-23 2016-08-30 Dental Alliance Holdings, Llc System for caries management by risk assessment
RU2493816C2 (ru) * 2006-04-07 2013-09-27 Дзе Проктер Энд Гэмбл Компани Способы и комплекты для ухода за полостью рта
EP2026650B1 (en) * 2006-06-14 2011-03-16 Basf Se Anti-microbial compositions
US20080025926A1 (en) * 2006-07-24 2008-01-31 Dr. Nick's White & Healthy, Llc Oral care formulations with hydrogen peroxide and lycopene
US10143633B2 (en) 2006-10-16 2018-12-04 Dental Alliance Holdings, Llc Treating cariogenic diseased oral biofilm with elevated pH
DE102006051891A1 (de) * 2006-10-31 2008-05-08 Schülke & Mayr GmbH Antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
EP2081542B2 (en) 2006-11-13 2017-09-13 The Procter and Gamble Company Products and methods for disclosing conditions in the oral cavity
US8741954B2 (en) * 2007-02-21 2014-06-03 Viratox, L.L.C. Synergistic enhancement of calcium propionate
JP5552725B2 (ja) * 2007-12-27 2014-07-16 ライオン株式会社 口腔用組成物及び口腔バイオフィルム殺菌剤
DE102008011691A1 (de) 2008-02-28 2009-09-10 Schülke & Mayr GmbH Stabilisierte, antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
US9849310B2 (en) 2008-06-24 2017-12-26 Dental Alliance Holdings, Llc Dental appliance, oral care product and method of preventing dental disease
WO2010129795A1 (en) * 2009-05-08 2010-11-11 3M Innovative Properties Company Oral care method and kit
EP2475431A2 (en) 2009-09-11 2012-07-18 The Procter & Gamble Company Methods and compositions for hydrophobic modification of oral cavity surfaces
TWI392514B (zh) 2010-01-29 2013-04-11 Colgate Palmolive Co 具有高微生物效力之不含氟化物及陰離子表面活性劑的潔牙劑
AU2011279823A1 (en) 2010-07-19 2013-02-07 The Procter & Gamble Company Compositions comprising derivatives of essential oil compounds and use in personal care products
EP2648705B1 (en) 2010-12-07 2016-11-16 Colgate-Palmolive Company Oral care compositions comprising a quinone and a further antimicrobial agent
BR112013018381A2 (pt) 2011-02-11 2017-09-05 Procter & Gamble Métodos, dispositivos e sistemas para reabstecimento de um dispensador de fluidos
US10426761B2 (en) 2011-04-19 2019-10-01 Arms Pharmaceutical, Llc Method for treatment of disease caused or aggravated by microorganisms or relieving symptoms thereof
CN103619341A (zh) 2011-04-19 2014-03-05 Arms制药有限公司 抑制有害微生物的方法及其阻隔形成组合物
WO2013052958A2 (en) 2011-10-08 2013-04-11 Microbial Defense Systems, Llc Antimicrobial compositions and methods employing same
CN103906500B (zh) * 2011-11-09 2017-08-08 高露洁-棕榄公司 无酒精漱口水
UA113298C2 (xx) * 2011-12-21 2017-01-10 Композиція для догляду за порожниною рота
US20150010479A1 (en) * 2012-03-20 2015-01-08 Sinclair Pharmaceuticals Limited Treatment of microbial infections
US10123953B2 (en) 2012-06-21 2018-11-13 The Procter & Gamble Company Reduction of tooth staining derived from cationic antimicrobials
US20130344120A1 (en) 2012-06-21 2013-12-26 Douglas Craig Scott Mouth Rinse Emulsions
WO2014074331A1 (en) * 2012-11-12 2014-05-15 ARMS Pharmaceutical LLC Low-tack surface anti-microbial coating composition and method of application
EP2934467B1 (en) * 2012-12-20 2018-09-26 Colgate-Palmolive Company Oral care composition containing ionic liquids
BR112015014993A2 (pt) * 2012-12-20 2017-07-11 Colgate Palmolive Co composição para higiene oral
US10398733B2 (en) 2013-03-15 2019-09-03 Cda Research Group, Inc. Topical copper ion treatments and methods of treatment using topical copper ion treatments in the dermatological areas of the body
US11318089B2 (en) 2013-03-15 2022-05-03 Cda Research Group, Inc. Topical copper ion treatments and methods of making topical copper ion treatments for use in various anatomical areas of the body
US11007143B2 (en) 2013-03-15 2021-05-18 Cda Research Group, Inc. Topical copper ion treatments and methods of treatment using topical copper ion treatments in the oral-respiratory-otic areas of the body
US11083750B2 (en) 2013-03-15 2021-08-10 Cda Research Group, Inc. Methods of treatment using topical copper ion formulations
US11000545B2 (en) 2013-03-15 2021-05-11 Cda Research Group, Inc. Copper ion compositions and methods of treatment for conditions caused by coronavirus and influenza
MX355921B (es) 2013-06-24 2018-05-03 Procter & Gamble Composicion para el cuidado bucal antimanchas.
US20150164778A1 (en) * 2013-12-18 2015-06-18 Honorio OBIAS Pre-mix and process for preparing personal care compositions, composition promoting improved and long-lasting cleansing sensory experience, improved oral care composition
EP2977109B1 (en) 2014-07-23 2020-03-11 Noxell Corporation Methods, devices and systems for refilling a liquid dispenser
EP2977108B1 (en) 2014-07-23 2018-12-12 Noxell Corporation Liquid refilling systems and devices
WO2016092499A1 (en) * 2014-12-12 2016-06-16 Jubilant Life Sciences Limited An improved process for the production of quaternary pyridinium salts
EP3252040B1 (en) * 2015-01-27 2023-04-19 BGI Shenzhen Stabilizer for preserving biological samples
JP6529158B2 (ja) * 2015-02-26 2019-06-12 ライオン株式会社 エアゾール型の歯間洗浄組成物
US20170151363A1 (en) 2015-11-27 2017-06-01 The Procter & Gamble Company Portable multi-fragrance compositional dispensing system and methods of use
CN105748507B (zh) * 2016-02-26 2018-04-17 陕西恒远生物科技有限公司 一种缓解口腔干燥的凝胶剂
WO2018031357A1 (en) 2016-08-11 2018-02-15 Colgate-Palmolive Company Oral care compositions
RU2687745C1 (ru) * 2018-03-21 2019-05-16 Закрытое акционерное общество "Институт фармацевтических технологий" (ЗАО "ИФТ") Комбинированное лекарственное средство в виде раствора для получения спрея для лечения заболеваний ротовой полости
BR112021010543A2 (pt) 2018-12-21 2021-08-24 Unilever Ip Holdings B.V. Composição antimicrobiana, método não terapêutico de tratamento da pele e/ou cavidade oral de um mamífero e uso de uma composição antimicrobiana
US11193184B2 (en) 2019-02-22 2021-12-07 Cda Research Group, Inc. System for use in producing a metal ion suspension and process of using same
EP3958983A1 (en) 2019-04-26 2022-03-02 The Procter & Gamble Company Reduction of tooth staining derived from cationic antimicrobials
JP7446099B2 (ja) 2019-12-06 2024-03-08 エア・ウォーター株式会社 歯の根管内および根管象牙細管内の感染治療用組成物

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988432A (en) * 1971-03-18 1976-10-26 Colgate-Palmolive Company Flavor and fragrant compositions
US3864472A (en) * 1972-11-06 1975-02-04 Colgate Palmolive Co Clear lemon-flavored mouthwash
GB1365030A (en) 1972-11-30 1974-08-29 Merck & Co Inc Oral compositions
US4022880A (en) * 1973-09-26 1977-05-10 Lever Brothers Company Anticalculus composition
US3956480A (en) * 1974-07-01 1976-05-11 Colgate-Palmolive Company Treatment of teeth
US4080440A (en) * 1974-12-13 1978-03-21 The Procter & Gamble Company Method for remineralizing tooth enamel
US4089880A (en) * 1975-03-13 1978-05-16 Sullivan Systems Inc. Proces for refining fatty oils
US4137303A (en) * 1975-06-18 1979-01-30 Colgate Palmolive Company Antibacterial oral composition
US4042679A (en) * 1975-11-07 1977-08-16 Colgate-Palmolive Company Antibacterial oral composition
US4370314A (en) * 1975-12-08 1983-01-25 Colgate-Palmolive Company Oral composition containing antibacterial agent
US4206215A (en) * 1976-02-25 1980-06-03 Sterling Drug Inc. Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes
US4118474A (en) * 1976-08-16 1978-10-03 Colgate-Palmolive Company Antibacterial oral composition
US4118476A (en) * 1976-08-16 1978-10-03 Colgate-Palmolive Company Antibacterial oral composition
US4118475A (en) * 1976-08-16 1978-10-03 Colgate-Palmolive Company Antibacterial oral composition
US4118472A (en) * 1976-08-16 1978-10-03 Colgate-Palmolive Company Antibacterial oral composition
US4118473A (en) * 1976-08-16 1978-10-03 Colgate-Palmolive Company Antibacterial oral composition
US4080441A (en) * 1976-12-27 1978-03-21 Colgate-Palmolive Company Antibacterial oral composition
US4188372A (en) * 1976-12-27 1980-02-12 Colgate-Palmolive Company Antibacterial oral composition
US4110429A (en) * 1976-12-30 1978-08-29 Colgate-Palmolive Company Antibacterial oral composition
US4183916A (en) * 1978-03-31 1980-01-15 Beecham Inc. Oral compositions
US4256730A (en) * 1978-08-24 1981-03-17 The Procter & Gamble Company Oral compositions
US4273759A (en) * 1979-05-18 1981-06-16 Colgate-Palmolive Company Antibacterial oral composition
US4224309A (en) * 1979-08-24 1980-09-23 Colgate-Palmolive Company Antibacterial oral composition
US4325939A (en) * 1980-09-22 1982-04-20 Richardson-Vicks Inc. Zinc derivatives and their use in dental compositions
US4289754A (en) * 1980-11-03 1981-09-15 Richardson-Vicks Inc. Zinc derivatives and their use in mouthwash compositions
US4339430A (en) * 1980-12-31 1982-07-13 Colgate-Palmolive Company Antibacterial oral composition
US4323551A (en) * 1981-02-19 1982-04-06 The Procter & Gamble Company Mouthwash compositions
US4663154A (en) * 1983-05-09 1987-05-05 The Procter & Gamble Company Oral compositions
US4472373A (en) * 1983-05-09 1984-09-18 The Procter & Gamble Company Oral compositions
US4959204A (en) * 1983-05-09 1990-09-25 The Proctor & Gamble Company Oral compositions
US4723759A (en) * 1986-12-17 1988-02-09 Davis Walker Corporation Welded wire fence panel
US5531982A (en) * 1987-01-30 1996-07-02 Colgate Palmolive Company Antimicrobial oral composition
US4994262A (en) * 1988-10-14 1991-02-19 The Procter & Gamble Company Oral compositions
US5256396A (en) * 1990-01-24 1993-10-26 Colgate-Palmolive Company Topical composition
JPH0684294B2 (ja) * 1990-05-29 1994-10-26 サンスター株式会社 口腔用組成物
US5158763A (en) * 1990-10-09 1992-10-27 Colgate-Palmolive Company Non-staining anti-bacterial oral composition
US5286479A (en) * 1991-12-10 1994-02-15 The Dow Chemical Company Oral compositions for suppressing mouth odors
US5374418A (en) * 1992-02-13 1994-12-20 Kao Corporation Composition for use in oral cavity
US5370865A (en) * 1992-05-15 1994-12-06 Kao Corporation Composition for use in oral cavity
US6440395B1 (en) * 1992-06-22 2002-08-27 Barry M. Libin Antiplaque mouth rinse
US5236699A (en) * 1992-06-22 1993-08-17 Libin Barry M Antiplaque mouth rinse
US5292527A (en) * 1992-07-02 1994-03-08 Bausch & Lomb Incorporated Non-alcoholic aqueous mouthwash
US5405604A (en) * 1992-10-16 1995-04-11 The Procter & Gamble Company Concentrated mouthrinse for efficient delivery of antimicrobials
GB9224598D0 (en) * 1992-11-24 1993-01-13 Smithkline Beecham Plc Novel compositions
DK0676948T3 (da) * 1992-12-16 2000-09-04 Colgate Palmolive Co Oral anti-plaque-, anti-gingivitis-, anti-caries-sammensætning
ZA94438B (en) 1993-02-19 1994-08-29 Warner Lambert Co Pre-brushing rinse composition
WO1994021386A2 (en) * 1993-03-25 1994-09-29 Research Corporation Technologies, Inc. Polymers useful in forming self-assembled bonded anisotropic ultrathin layers and their use
WO1994027566A1 (en) 1993-05-20 1994-12-08 Warner-Lambert Company Improved peppermint flavor for oral hygiene products
KR100304064B1 (ko) * 1993-08-12 2001-11-22 다카하시 미치나오 구강용조성물
US5451401A (en) * 1993-09-29 1995-09-19 The Procter & Gamble Company Diphosphonic acid esters as tartar control agents
EP0735856A1 (en) 1993-12-22 1996-10-09 The Procter & Gamble Company Concentrated mouthrinse for efficient delivery of antimicrobials
EP0764015B1 (en) * 1994-06-10 2000-04-19 The Procter & Gamble Company Mouthrinse compositions
WO1996015770A1 (en) 1994-11-17 1996-05-30 Warner-Lambert Company Antimicrobial oral compositions
US5560906A (en) * 1995-03-27 1996-10-01 Oral Technology Laboratories, Inc. Non-alcoholic antimicrobial mouthwash for removal of dental plaque
GB9611364D0 (en) * 1996-05-31 1996-08-07 Smithkline Beecham Plc Composition
US5948390A (en) * 1997-08-25 1999-09-07 Pfizer Inc. Stable zinc/citrate/CPC oral rinse formulations
US5980925A (en) * 1997-12-30 1999-11-09 Ethicon, Inc. High glycerin containing anti-microbial cleansers
US6861047B1 (en) 1999-01-27 2005-03-01 Victor Carnell Oral hygiene preparations; associated methods and kit
NO307168B1 (no) * 1999-03-01 2000-02-21 Orix As Oralt preparat som er effektivt mot halitose
US20020068039A1 (en) * 2000-07-28 2002-06-06 Pan Pauline C. Oral care compositions containing grapefruit seed extract
EP1370226A2 (en) * 2001-01-24 2003-12-17 Oraceutical LLC Topical oral care compositions
US6355229B1 (en) * 2001-06-27 2002-03-12 Church & Dwight Co., Inc. Oral composition containing cetylpyridinium chloride and guar hydroxypropyltrimonium chloride and method of using the same
US6723305B2 (en) 2002-03-04 2004-04-20 Colgate Palmolive Company Anti-microbial breath freshening mouthrinse

Also Published As

Publication number Publication date
EP1708791A1 (en) 2006-10-11
PL1708791T3 (pl) 2017-03-31
CA2774961C (en) 2014-01-07
ES2606336T3 (es) 2017-03-23
EP1708791B1 (en) 2016-10-05
US20050169852A1 (en) 2005-08-04
CA2554730A1 (en) 2005-08-11
MXPA06008604A (es) 2006-08-28
US9241885B2 (en) 2016-01-26
JP2007518828A (ja) 2007-07-12
CN1909875A (zh) 2007-02-07
RU2006127137A (ru) 2008-03-10
CA2774961A1 (en) 2005-08-11
CA2554730C (en) 2012-05-29
WO2005072693A1 (en) 2005-08-11
CN1909875B (zh) 2012-09-05
RU2325899C2 (ru) 2008-06-10

Similar Documents

Publication Publication Date Title
BRPI0507187A (pt) composições para tratamento bucal compreendendo teores biodisponìveis mais altos de compostos antimicrobianos à base de amÈnio quaternário
Ren et al. Orthodontic treatment with fixed appliances and biofilm formation—a potential public health threat?
Almaz et al. Ozone therapy in the management and prevention of caries
Fung et al. Arresting early childhood caries with silver diamine fluoride-a literature review
ES2632363T3 (es) Composición farmacéutica antiséptica para la higiene bucal y el tratamiento de enfermedades bucales de origen microbiano
Santamaria Jr et al. Antimicrobial effect of Melaleuca alternifolia dental gel in orthodontic patients
Meyer et al. Hydroxyapatite in oral biofilm management
JP5804307B2 (ja) 口腔用組成物
WO2005030141A3 (en) Morinda citrifolia-based oral care compositions and methods
ATE396772T1 (de) Feste orale anti-zahnstein- und anti- plaquezubereitungen
Delgado et al. A clinical investigation of a dual zinc plus arginine dentifrice in reducing established dental plaque and gingivitis over a six-month period of product use
Srinivasan et al. Ozone: A paradigm shift in dental therapy
EA200701152A1 (ru) Состав для профилактики заболеваний полости рта
Hu et al. A clinical investigation of the efficacy of a dual zinc plus arginine dentifrice for controlling oral malodor
Hosseinpour-Nader et al. Effect of nanomicelle curcumin-based photodynamic therapy on the dynamics of white spot lesions and virulence of Streptococcus mutans in patients undergoing fixed orthodontic treatment: A randomized double-blind clinical trial
PE103198A1 (es) Composiciones antimicrobianas para el cuidado bucal y composiciones para el tratamiento de la enfermedad periodontal y el mal olor del aliento
Sikka et al. Comparative anti-plaque and anti-gingivitis efficacy of two commercially available mouthwashes-4 weeks clinical study
Talasani et al. Efficacy of ozonated water over chlorhexidine mouth rinse in chronic gingivitis patients–A comparative clinical study
ATE322883T1 (de) Feste mundpflegezusammensetzungen
Haas et al. Daily biofilm control and oral health: an epidemiological challenge consensus brazilian advisory panel in oral health
McGrath et al. Effectiveness of mouthwashes in managing oral diseases and conditions: do they have a role?
Jyoti et al. Ozone in dental therapy: an outlook
ES2811799T3 (es) Utilización de estatinas para la enfermedad periodontal y regeneración ósea
PE102898A1 (es) Composiciones antimicrobianas para el cuidado bucal y composiciones para el tratamiento de la enfermedad periodontal y el mal olor del aliento
Habibullah Silver diamine fluoride: Is silver the new gold standard in caries prevention?: a narrative review

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 11, 13 E 25 DA LPI

B09B Decision: refusal

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.