BRPI0506536A - células tronco do tipo embriÈnico pluripotentes derivadas do limbus da córnea, métodos de isolamento e uso das mesmas - Google Patents

células tronco do tipo embriÈnico pluripotentes derivadas do limbus da córnea, métodos de isolamento e uso das mesmas

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Publication number
BRPI0506536A
BRPI0506536A BRPI0506536-4A BRPI0506536A BRPI0506536A BR PI0506536 A BRPI0506536 A BR PI0506536A BR PI0506536 A BRPI0506536 A BR PI0506536A BR PI0506536 A BRPI0506536 A BR PI0506536A
Authority
BR
Brazil
Prior art keywords
stem cells
elscs
pluripotent embryonic
embryonic
isolation methods
Prior art date
Application number
BRPI0506536-4A
Other languages
English (en)
Inventor
Satish Totey Mahadeorao
Subhadra Devi Kashyap
Firdos Alam Khan
Rajarshi Pal
Aparna Khanna
Shabri Tipnis
Geeta Ravindran
Original Assignee
Reliance Life Sciences Pvt Ltd
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Publication date
Application filed by Reliance Life Sciences Pvt Ltd filed Critical Reliance Life Sciences Pvt Ltd
Publication of BRPI0506536A publication Critical patent/BRPI0506536A/pt
Publication of BRPI0506536C1 publication Critical patent/BRPI0506536C1/pt

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    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/067—Hepatocytes
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/08—Coculture with; Conditioned medium produced by cells of the nervous system
    • C12N2502/085—Coculture with; Conditioned medium produced by cells of the nervous system eye cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

CéLULAS TRONCO DO TIPO EMBRIÈNICO PLURIPOTENTES DERIVADAS DO LIMBUS DA CóRNEA, MéTODOS DE ISOLAMENTO E USOS DAS MESMAS, mais precisamente a presente invenção apresenta células tronco do tipo embriónico (ELSCs) pluripotentes de um mamífero isoladas de tecidos límbico de córnea, um tecido não embriónico, onde as ELSCs têm a capacidade de proliferar em uma cultura in vitro, mantêm o potencial para se diferenciar em células da linhagem de endoderme, mesoderme, e ectoderme em cultura, e têm a capacidade de formar corpos do tipo embrióide quando colocadas em cultura em suspensão e, desse modo, essas célula possuem o potencial de diferenciação de múltiplas linhagens e capacidade de se auto-renovarem, sendo que as ditas ELSCs podem ser uma ferramenta terapêutica promissora, e podem fornecer novas alternativas terapêuticas para várias doenças, condições e ferimentos.
BRC10506536-4A 2004-02-26 2005-02-23 neurÈnios dopaminérgicos derivados do limbus corneal, métodos de isolamento e usos dos mesmos BRPI0506536C1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN240MU2004 2004-02-26
US62147604P 2004-10-22 2004-10-22
PCT/IB2005/000516 WO2005084119A2 (en) 2004-02-26 2005-02-23 Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof

Publications (2)

Publication Number Publication Date
BRPI0506536A true BRPI0506536A (pt) 2007-05-15
BRPI0506536C1 BRPI0506536C1 (pt) 2007-05-22

Family

ID=34921522

Family Applications (1)

Application Number Title Priority Date Filing Date
BRC10506536-4A BRPI0506536C1 (pt) 2004-02-26 2005-02-23 neurÈnios dopaminérgicos derivados do limbus corneal, métodos de isolamento e usos dos mesmos

Country Status (6)

Country Link
EP (1) EP1758984A2 (pt)
KR (3) KR100840979B1 (pt)
AU (1) AU2005220066B2 (pt)
BR (1) BRPI0506536C1 (pt)
IL (2) IL177672A (pt)
WO (1) WO2005084119A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186672A1 (en) * 2004-01-27 2005-08-25 Reliance Life Sciences Pvt. Ltd. Tissue system with undifferentiated stem cells derived from corneal limbus
WO2008026226A2 (en) * 2006-09-01 2008-03-06 Stempeutics Research Private Limited Self-renewing master adult pluripotent stem cells
EP2539441B1 (en) * 2010-02-22 2016-09-28 Université Pierre et Marie Curie (Paris 6) Cell culture medium for the growth and differentiation of cells of the hematopoietic lineage
KR101323650B1 (ko) * 2011-05-04 2013-11-05 연세대학교 산학협력단 미분화 전능성 줄기세포의 제거방법
KR102038503B1 (ko) * 2015-08-12 2019-11-26 (주) 넥셀 고기능성 간세포의 분화방법
KR101645901B1 (ko) * 2015-12-31 2016-08-04 가톨릭대학교 산학협력단 양막 슬라이드 지지체를 이용한 윤부줄기세포 배양방법
KR101789917B1 (ko) 2016-03-29 2017-10-26 가톨릭대학교 산학협력단 윤부줄기세포의 증식 및 줄기세포능을 증대시키는 방법
CN107345897A (zh) * 2016-05-04 2017-11-14 上海米洋杨生物科技有限公司 一种视网膜感光细胞特异性表面蛋白的筛选方法
US20190352611A1 (en) * 2016-11-18 2019-11-21 Regents Of The University Of Minnesota Surface markers for the isolation of myogenic stem/progenitor cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703047A (en) 1992-09-21 1997-12-30 Board Of Regents, The University Of Texas System Methods and treatments for corneal healing with growth factors
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US20030161817A1 (en) * 2001-03-28 2003-08-28 Young Henry E. Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
ITRM20010476A1 (it) * 2001-08-03 2003-02-03 Idi Irccs Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.
US7422736B2 (en) * 2002-07-26 2008-09-09 Food Industry Research And Development Institute Somatic pluripotent cells

Also Published As

Publication number Publication date
KR100840979B1 (ko) 2008-06-24
EP1758984A2 (en) 2007-03-07
KR20090021229A (ko) 2009-02-27
AU2005220066B2 (en) 2010-01-21
KR20060114372A (ko) 2006-11-06
IL177671A0 (en) 2008-03-20
KR100931887B1 (ko) 2009-12-15
AU2005220066A1 (en) 2005-09-15
WO2005084119A2 (en) 2005-09-15
KR20080036636A (ko) 2008-04-28
WO2005084119A3 (en) 2010-06-17
BRPI0506536C1 (pt) 2007-05-22
IL177672A (en) 2011-03-31
IL177672A0 (en) 2008-03-20

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