BRPI0417810B8 - arilpirazóis substituídos como agentes parasiticidas, composição veterinária e uso dos mesmos - Google Patents

arilpirazóis substituídos como agentes parasiticidas, composição veterinária e uso dos mesmos

Info

Publication number
BRPI0417810B8
BRPI0417810B8 BRPI0417810A BRPI0417810A BRPI0417810B8 BR PI0417810 B8 BRPI0417810 B8 BR PI0417810B8 BR PI0417810 A BRPI0417810 A BR PI0417810A BR PI0417810 A BRPI0417810 A BR PI0417810A BR PI0417810 B8 BRPI0417810 B8 BR PI0417810B8
Authority
BR
Brazil
Prior art keywords
veterinary composition
parasiticidal agents
substituted arylpyrazoles
arylpyrazoles
substituted
Prior art date
Application number
BRPI0417810A
Other languages
English (en)
Inventor
Morris Gethin David
Billen Denis
Thomas Hall Kim
Richard Roberts Lee
Anthony Logan Chubb Nathan
Derek Arthur Walshe Nigel
Original Assignee
Ah Usa 42 Llc
Pfizer
Zoetis Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ah Usa 42 Llc, Pfizer, Zoetis Llc filed Critical Ah Usa 42 Llc
Publication of BRPI0417810A publication Critical patent/BRPI0417810A/pt
Publication of BRPI0417810B1 publication Critical patent/BRPI0417810B1/pt
Publication of BRPI0417810B8 publication Critical patent/BRPI0417810B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

"arilpirazóis substituídos como agentes parasiticidas". essa invenção se refere a uma faixa de 1-aril-4-ciclopropil-pirazóis nos quais existe pelo menos um flúor anexado ao anel ciclopropila, às composições compreendendo tais compostos, aos processos para sua síntese e seu uso como parasiticidas.
BRPI0417810A 2003-12-18 2004-12-15 arilpirazóis substituídos como agentes parasiticidas, composição veterinária e uso dos mesmos BRPI0417810B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329314.9A GB0329314D0 (en) 2003-12-18 2003-12-18 Substituted arylpyrazoles
PCT/IB2004/004193 WO2005060749A1 (en) 2003-12-18 2004-12-15 Substituted arylpyrazoles as parasiticidal agents

Publications (3)

Publication Number Publication Date
BRPI0417810A BRPI0417810A (pt) 2007-04-10
BRPI0417810B1 BRPI0417810B1 (pt) 2018-11-21
BRPI0417810B8 true BRPI0417810B8 (pt) 2021-05-25

Family

ID=30471290

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417810A BRPI0417810B8 (pt) 2003-12-18 2004-12-15 arilpirazóis substituídos como agentes parasiticidas, composição veterinária e uso dos mesmos

Country Status (33)

Country Link
US (1) US7435753B2 (pt)
EP (1) EP1705989B8 (pt)
JP (2) JP4805164B2 (pt)
KR (1) KR100815637B1 (pt)
CN (1) CN100377645C (pt)
AR (1) AR046942A1 (pt)
AT (1) ATE413809T1 (pt)
AU (1) AU2004304717B2 (pt)
BR (1) BRPI0417810B8 (pt)
CA (1) CA2549479C (pt)
CY (1) CY1108649T1 (pt)
DE (1) DE602004017782D1 (pt)
DK (1) DK1705989T3 (pt)
EA (1) EA010740B1 (pt)
ES (1) ES2315724T3 (pt)
GB (1) GB0329314D0 (pt)
HK (1) HK1096824A1 (pt)
IL (1) IL175992A0 (pt)
IS (1) IS8492A (pt)
MA (1) MA28269A1 (pt)
MX (1) MXPA06007006A (pt)
NO (1) NO20062549L (pt)
NZ (1) NZ547565A (pt)
PL (1) PL1705989T3 (pt)
PT (1) PT1705989E (pt)
RS (1) RS51111B (pt)
SI (1) SI1705989T1 (pt)
TN (1) TNSN06187A1 (pt)
TW (1) TW200526605A (pt)
UA (1) UA83397C2 (pt)
UY (1) UY28670A1 (pt)
WO (1) WO2005060749A1 (pt)
ZA (1) ZA200604715B (pt)

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US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
ATE456557T1 (de) * 2005-06-15 2010-02-15 Pfizer Ltd Substituierte arylpyrazole zur verwendung gegen parasiten
EP1968578A4 (en) 2005-12-14 2011-02-23 Makhteshim Chem Works Ltd POLYMORPHIC AND AMORPHOUS FORMS OF 5-AMINO-L- [2,6-DICHLORO-4- (TRIFLUOROMETHYL) PHENYL] -4- [(TRIFLUOROMETHYL) SULFINYL] -IH-PYRAZOLE-3-CARBONITRIL
FR2928919B1 (fr) * 2008-03-19 2011-07-29 Rhodia Operations Procede de preparation de l'acide difluoroacetique et de ses sels
WO2010017902A1 (de) 2008-08-14 2010-02-18 Bayer Cropscience Aktiengesellschaft Insektizide 4-phenyl-1h-pyrazole
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
PL2443093T3 (pl) * 2009-03-16 2014-04-30 Basf Agro B V Arnhem Nl Zuerich Branch Sposób wytwarzania pochodnych pirazolu
EP2253617A1 (de) 2009-05-20 2010-11-24 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
WO2011066505A2 (en) * 2009-11-30 2011-06-03 Pathak Holdings Llc Methods and compositions for filling fleshy fruits and vegetables
JP2013523805A (ja) 2010-04-08 2013-06-17 ゾエティス・エルエルシー 殺虫剤および殺ダニ剤としての置換３，５−ジフェニル−イソオキサゾリン誘導体
JP2012046486A (ja) * 2010-07-30 2012-03-08 Sumitomo Chemical Co Ltd 動物外部寄生虫防除剤
JP5409968B2 (ja) 2010-08-05 2014-02-05 ゾエティス・エルエルシー 駆虫剤としてのイソオキサゾリン誘導体
EP2619189B1 (en) 2010-09-24 2020-04-15 Zoetis Services LLC Isoxazoline oximes as antiparasitic agents
FR2972452B1 (fr) * 2011-03-09 2013-03-15 Rhodia Operations Procede de preparation du difluoroacetonitrile et de ses derives
RU2566083C3 (ru) 2011-03-10 2017-11-09 Зоетис Сервисиз ЛЛК Спироциклические производные изоксазолина в качестве противопаразитарных агентов
EP2688876A1 (en) 2011-03-22 2014-01-29 Zoetis Llc Isoxazoline derivatives as antiparasitic agents
MX336430B (es) 2012-02-03 2016-01-18 Zoetis Services Llc Derivados de dihidrofurano-azetadina como agentes antiparasitarios.
US9073912B2 (en) 2012-05-09 2015-07-07 Zoetis Services Llc Azetidine derivatives as antiparasitic agents
WO2014093481A1 (en) 2012-12-12 2014-06-19 Zoetis Llc Phenylpyrazole injectable compositions

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Also Published As

Publication number Publication date
UY28670A1 (es) 2005-07-29
HK1096824A1 (en) 2007-06-15
AR046942A1 (es) 2006-01-04
KR20060101777A (ko) 2006-09-26
US20050148649A1 (en) 2005-07-07
UA83397C2 (uk) 2008-07-10
ZA200604715B (en) 2007-03-28
IL175992A0 (en) 2006-10-05
CN1893825A (zh) 2007-01-10
CN100377645C (zh) 2008-04-02
TW200526605A (en) 2005-08-16
PL1705989T3 (pl) 2009-04-30
KR100815637B1 (ko) 2008-03-20
EP1705989B8 (en) 2009-03-25
MA28269A1 (fr) 2006-11-01
ATE413809T1 (de) 2008-11-15
JP4805164B2 (ja) 2011-11-02
AU2004304717B2 (en) 2010-11-18
TNSN06187A1 (fr) 2007-11-15
JP2007514735A (ja) 2007-06-07
RS51111B (sr) 2010-10-31
EP1705989B1 (en) 2008-11-12
JP2008174563A (ja) 2008-07-31
DK1705989T3 (da) 2009-01-19
WO2005060749A1 (en) 2005-07-07
GB0329314D0 (en) 2004-01-21
DE602004017782D1 (de) 2008-12-24
US7435753B2 (en) 2008-10-14
SI1705989T1 (sl) 2009-02-28
NO20062549L (no) 2006-06-27
BRPI0417810A (pt) 2007-04-10
AU2004304717A1 (en) 2005-07-07
PT1705989E (pt) 2009-01-20
MXPA06007006A (es) 2006-08-31
IS8492A (is) 2006-05-31
EP1705989A1 (en) 2006-10-04
CA2549479A1 (en) 2005-07-07
CA2549479C (en) 2009-08-18
EA200600979A1 (ru) 2006-10-27
CY1108649T1 (el) 2014-04-09
BRPI0417810B1 (pt) 2018-11-21
NZ547565A (en) 2009-07-31
EA010740B1 (ru) 2008-10-30
ES2315724T3 (es) 2009-04-01

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