BRPI0412798A - uso de uma combinação de um antagonista de fator de crescimento endotelial vascular e um agente antiproliferativo, método de inibir ou reduzir o crescimento de tumor, composição farmacêutica, uso de uma combinação de um antagonista de vegf e um agente quimioterapêutico, e, artigo de fabricação - Google Patents
uso de uma combinação de um antagonista de fator de crescimento endotelial vascular e um agente antiproliferativo, método de inibir ou reduzir o crescimento de tumor, composição farmacêutica, uso de uma combinação de um antagonista de vegf e um agente quimioterapêutico, e, artigo de fabricaçãoInfo
- Publication number
- BRPI0412798A BRPI0412798A BRPI0412798-6A BRPI0412798A BRPI0412798A BR PI0412798 A BRPI0412798 A BR PI0412798A BR PI0412798 A BRPI0412798 A BR PI0412798A BR PI0412798 A BRPI0412798 A BR PI0412798A
- Authority
- BR
- Brazil
- Prior art keywords
- combination
- antagonist
- agent
- pharmaceutical composition
- inhibiting
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
"USO DE UMA COMBINAçãO DE UM ANTAGONISTA DE FATOR DE CRESCIMENTO ENDOTELIAL VASCULAR E UM AGENTE ANTIPROLIFERATIVO, MéTODO DE INIBIR OU REDUZIR O CRESCIMENTO DE TUMOR, COMPOSIçãO FARMACêUTICA, USO DE UMA COMBINAçãO DE UM ANTAGONISTA DE VEGF E UM AGENTE QUIMIOTERAPêUTICO, E, ARTIGO DE FABRICAçãO". Métodos de tratar câncer e/ou reduzir ou inibir o crescimento de tumor em um indivíduo em necessidade deste, que compreende administrar a composição farmacêutica que compreende um antagonista fator de crescimento celular endotelial vascular (VEGF), tais como uma armadilha de VEGF, um agente anti-proliferativo, tal como taxol e um carreador farmaceuticamente aceitável.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49000203P | 2003-07-25 | 2003-07-25 | |
US49397103P | 2003-08-08 | 2003-08-08 | |
PCT/US2004/023815 WO2005011734A2 (en) | 2003-07-25 | 2004-07-23 | Composition of a vegf antagonist and an anti-proliferative agent and its use for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0412798A true BRPI0412798A (pt) | 2006-09-26 |
Family
ID=34118812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0412798-6A BRPI0412798A (pt) | 2003-07-25 | 2004-07-23 | uso de uma combinação de um antagonista de fator de crescimento endotelial vascular e um agente antiproliferativo, método de inibir ou reduzir o crescimento de tumor, composição farmacêutica, uso de uma combinação de um antagonista de vegf e um agente quimioterapêutico, e, artigo de fabricação |
Country Status (17)
Country | Link |
---|---|
US (1) | US7354579B2 (pt) |
EP (1) | EP1648428A2 (pt) |
JP (1) | JP5355856B2 (pt) |
KR (1) | KR101175990B1 (pt) |
AR (1) | AR046510A1 (pt) |
AU (1) | AU2004261165C1 (pt) |
BR (1) | BRPI0412798A (pt) |
CA (1) | CA2529742C (pt) |
IL (1) | IL172406A (pt) |
MX (1) | MXPA05013642A (pt) |
MY (1) | MY149169A (pt) |
NO (1) | NO20060924L (pt) |
NZ (1) | NZ544570A (pt) |
RU (1) | RU2353353C2 (pt) |
TW (1) | TWI351953B (pt) |
UY (1) | UY28438A1 (pt) |
WO (1) | WO2005011734A2 (pt) |
Families Citing this family (69)
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US20050271663A1 (en) * | 2001-06-28 | 2005-12-08 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
US9321832B2 (en) * | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
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US7696320B2 (en) | 2004-08-24 | 2010-04-13 | Domantis Limited | Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor |
CA2511910A1 (en) * | 2002-12-27 | 2004-07-15 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
AU2004247095A1 (en) * | 2003-06-06 | 2004-12-23 | Regeneron Pharmaceuticals, Inc. | Use of VEGF inhibitors for tumor regression |
FR2878749B1 (fr) * | 2004-12-03 | 2007-12-21 | Aventis Pharma Sa | Combinaisons antitumorales contenant en agent inhibiteur de vegt et du 5fu ou un de ses derives |
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SI2364691T1 (sl) | 2006-06-16 | 2013-08-30 | Regeneron Pharmaceuticals, Inc. | Formulacije antagonista VEGF, primerne za intravitrealno dajanje |
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CA2683801A1 (en) * | 2007-06-06 | 2008-12-11 | Domantis Limited | Polypeptides, antibody variable domains and antagonists |
FR2918279B1 (fr) * | 2007-07-05 | 2010-10-22 | Aventis Pharma Sa | Combinaisons antitumorales contenant un agent inhibiteur de vegf et de l'irinotecan |
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ES2958968T3 (es) * | 2008-06-17 | 2024-02-16 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
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TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體-抗體組合物及其製造及使用方法 |
CA2998673C (en) | 2015-09-23 | 2023-12-12 | Aerpio Therapeutics, Inc. | Methods of treating intraocular pressure with activators of tie-2 |
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IL308505A (en) | 2021-05-17 | 2024-01-01 | Regeneron Pharma | Continuous high-dose VEGF antagonist regimens for the treatment of angiogenic ocular disorders |
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US6811779B2 (en) * | 1994-02-10 | 2004-11-02 | Imclone Systems Incorporated | Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy |
US6100071A (en) * | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
ATE269357T1 (de) * | 1999-04-28 | 2004-07-15 | Univ Texas | Zusammensetzungen und verfahren zur krebsbehandlung durch die selektive hemmung von vegf |
ES2237429T3 (es) * | 1999-06-08 | 2005-08-01 | Regeneron Pharmaceuticals, Inc. | Polipeptidos quimericos modificados con propiedades farmacocineticas mejoradas. |
AU2004247095A1 (en) * | 2003-06-06 | 2004-12-23 | Regeneron Pharmaceuticals, Inc. | Use of VEGF inhibitors for tumor regression |
-
2004
- 2004-07-21 AR ARP040102585A patent/AR046510A1/es unknown
- 2004-07-23 MX MXPA05013642A patent/MXPA05013642A/es not_active Application Discontinuation
- 2004-07-23 JP JP2006521281A patent/JP5355856B2/ja active Active
- 2004-07-23 RU RU2006105496/15A patent/RU2353353C2/ru active
- 2004-07-23 TW TW093121978A patent/TWI351953B/zh active
- 2004-07-23 CA CA2529742A patent/CA2529742C/en active Active
- 2004-07-23 KR KR1020067000521A patent/KR101175990B1/ko active IP Right Grant
- 2004-07-23 US US10/897,802 patent/US7354579B2/en active Active
- 2004-07-23 WO PCT/US2004/023815 patent/WO2005011734A2/en active Application Filing
- 2004-07-23 AU AU2004261165A patent/AU2004261165C1/en active Active
- 2004-07-23 NZ NZ544570A patent/NZ544570A/en unknown
- 2004-07-23 EP EP04779050A patent/EP1648428A2/en not_active Withdrawn
- 2004-07-23 MY MYPI20042968A patent/MY149169A/en unknown
- 2004-07-23 BR BRPI0412798-6A patent/BRPI0412798A/pt not_active Application Discontinuation
- 2004-07-26 UY UY28438A patent/UY28438A1/es not_active Application Discontinuation
-
2005
- 2005-12-06 IL IL172406A patent/IL172406A/en not_active IP Right Cessation
-
2006
- 2006-02-24 NO NO20060924A patent/NO20060924L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20060028654A (ko) | 2006-03-30 |
WO2005011734A2 (en) | 2005-02-10 |
WO2005011734A3 (en) | 2005-04-14 |
KR101175990B1 (ko) | 2012-08-23 |
TW200524589A (en) | 2005-08-01 |
RU2353353C2 (ru) | 2009-04-27 |
AU2004261165B2 (en) | 2009-07-16 |
MXPA05013642A (es) | 2006-03-10 |
TWI351953B (en) | 2011-11-11 |
US20050032699A1 (en) | 2005-02-10 |
AR046510A1 (es) | 2005-12-14 |
JP5355856B2 (ja) | 2013-11-27 |
JP2007500131A (ja) | 2007-01-11 |
IL172406A0 (en) | 2006-04-10 |
NO20060924L (no) | 2006-04-25 |
CA2529742A1 (en) | 2005-02-10 |
MY149169A (en) | 2013-07-31 |
AU2004261165A1 (en) | 2005-02-10 |
IL172406A (en) | 2016-04-21 |
UY28438A1 (es) | 2004-11-08 |
AU2004261165C1 (en) | 2009-12-17 |
US7354579B2 (en) | 2008-04-08 |
EP1648428A2 (en) | 2006-04-26 |
NZ544570A (en) | 2008-08-29 |
CA2529742C (en) | 2012-09-18 |
RU2006105496A (ru) | 2006-06-10 |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
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