BRPI0412492A - método para desinfectar sangue e frações de sangue - Google Patents
método para desinfectar sangue e frações de sangueInfo
- Publication number
- BRPI0412492A BRPI0412492A BRPI0412492-8A BRPI0412492A BRPI0412492A BR PI0412492 A BRPI0412492 A BR PI0412492A BR PI0412492 A BRPI0412492 A BR PI0412492A BR PI0412492 A BRPI0412492 A BR PI0412492A
- Authority
- BR
- Brazil
- Prior art keywords
- blood
- virus
- fractions
- ascorbate
- dye
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"MéTODO PARA DESINFECTAR SANGUE E FRAçõES DE SANGUE". O tratamento de sangue ou frações de sangue com uma mistura de azul de metileno e violeta cristal ('corante duplo') foi verificado como eliminado várias bactérias, vírus e parasitas sem danificar de modo apreciável as células de sangue ou proteínas. Uma redução de 4 log em Staphylococcus epidermitis, Staphylococcus Aureus, Bacillus subtilis, Escherichia coli, Yersinia enterocolitica, Pseudomonas aeruginosa, Pseudomonas fluorescens e Serratia marcescens foi observada. As mortes completas de vírus de estomatite vesicular, vírus de encefalomiocardite, vírus de diarréia viral bovina, e parvovirus porcino foram obtidas por adição de ascorbato suficiente para converter em grande parte os dois corantes em suas formas leuco. Finalmente, um método de filtração de PVA é usado para remover os corantes antes de uso do sangue ou componente de sangue desinfetado. Assim, o método de corante duplo-ascorbato-PVA é um modo eficaz, de baixo custo, para eliminar patógenos de sangue total, plaquetas, plasma ou outras frações de sangue.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48716003P | 2003-07-11 | 2003-07-11 | |
PCT/US2004/022583 WO2005006861A2 (en) | 2003-07-11 | 2004-07-12 | Double dye method to inactivate blood borne pathogens |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0412492A true BRPI0412492A (pt) | 2006-09-19 |
Family
ID=34079349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0412492-8A BRPI0412492A (pt) | 2003-07-11 | 2004-07-12 | método para desinfectar sangue e frações de sangue |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1643837B1 (pt) |
AT (1) | ATE430474T1 (pt) |
AU (1) | AU2004257761B2 (pt) |
BR (1) | BRPI0412492A (pt) |
DE (1) | DE602004020991D1 (pt) |
ES (1) | ES2328575T3 (pt) |
MX (1) | MXPA06000438A (pt) |
WO (1) | WO2005006861A2 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007038201A1 (en) * | 2005-09-23 | 2007-04-05 | Bioenvision, Inc. | Methylene blue therapy of parasitic infections |
EP2249661B1 (en) | 2008-01-22 | 2018-05-16 | Multimerics APS | Products and methods to prevent infection |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5742625A (en) * | 1980-08-28 | 1982-03-10 | Yutaka Idota | Remedy of prophylactic against various kinds of swine diseases |
FI942576A0 (fi) * | 1994-06-01 | 1994-06-01 | Suomen Punainen Risti Veripalv | Behandling av plasma |
US5811471A (en) * | 1997-09-15 | 1998-09-22 | Shanbrom Technologies Llc | Disinfectant plastic sponge material |
ES2197483T3 (es) * | 1998-07-16 | 2004-01-01 | Shanbrom Technologies, Llc | Eliminacion de colorantes desinfectantes. |
-
2004
- 2004-07-12 DE DE602004020991T patent/DE602004020991D1/de not_active Expired - Lifetime
- 2004-07-12 ES ES04778209T patent/ES2328575T3/es not_active Expired - Lifetime
- 2004-07-12 WO PCT/US2004/022583 patent/WO2005006861A2/en active Application Filing
- 2004-07-12 BR BRPI0412492-8A patent/BRPI0412492A/pt not_active IP Right Cessation
- 2004-07-12 AU AU2004257761A patent/AU2004257761B2/en not_active Ceased
- 2004-07-12 AT AT04778209T patent/ATE430474T1/de active
- 2004-07-12 EP EP04778209A patent/EP1643837B1/en not_active Expired - Lifetime
- 2004-07-12 MX MXPA06000438A patent/MXPA06000438A/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
AU2004257761B2 (en) | 2008-10-09 |
WO2005006861A3 (en) | 2005-04-21 |
AU2004257761A1 (en) | 2005-01-27 |
WO2005006861A2 (en) | 2005-01-27 |
DE602004020991D1 (de) | 2009-06-18 |
ATE430474T1 (de) | 2009-05-15 |
MXPA06000438A (es) | 2006-04-05 |
EP1643837A2 (en) | 2006-04-12 |
EP1643837B1 (en) | 2009-05-06 |
ES2328575T3 (es) | 2009-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2314 DE 12-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |