BRPI0411895A - formulações para o tratamento de condições de artrite - Google Patents

formulações para o tratamento de condições de artrite

Info

Publication number
BRPI0411895A
BRPI0411895A BRPI0411895-2A BRPI0411895A BRPI0411895A BR PI0411895 A BRPI0411895 A BR PI0411895A BR PI0411895 A BRPI0411895 A BR PI0411895A BR PI0411895 A BRPI0411895 A BR PI0411895A
Authority
BR
Brazil
Prior art keywords
formulations
arthritis conditions
treating arthritis
conditions
treatment
Prior art date
Application number
BRPI0411895-2A
Other languages
English (en)
Inventor
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of BRPI0411895A publication Critical patent/BRPI0411895A/pt
Publication of BRPI0411895B1 publication Critical patent/BRPI0411895B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/76—Salicaceae (Willow family), e.g. poplar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Saccharide Compounds (AREA)
  • Road Signs Or Road Markings (AREA)

Abstract

"FORMULAçõES PARA O TRATAMENTO DE CONDIçõES DE ARTRITE". A presente invenção refere-se a formulações contendo combinações de agentes analgésicos/antiinflamatórios, imunomoduladores e de reconstrução de cartilagem, em particular contendo saligenina, ácido boswélico, procianidinas, N-acetil-glicosamina e ácido glicurónico ou glicuronolactona, para o tratamento de artrite reumatóide e, mais geralmente, de condições de artrite.
BRPI0411895A 2003-06-27 2004-06-01 formulações contendo saligenina e ácido boswélico, e seu uso BRPI0411895B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001311A ITMI20031311A1 (it) 2003-06-27 2003-06-27 Formulazioni per il trattamento di disturbi artrosici.
PCT/EP2004/005875 WO2005002611A1 (en) 2003-06-27 2004-06-01 Formulations for the treatment of arhritis conditions

Publications (2)

Publication Number Publication Date
BRPI0411895A true BRPI0411895A (pt) 2006-08-29
BRPI0411895B1 BRPI0411895B1 (pt) 2015-11-10

Family

ID=30131307

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411895A BRPI0411895B1 (pt) 2003-06-27 2004-06-01 formulações contendo saligenina e ácido boswélico, e seu uso

Country Status (21)

Country Link
US (1) US8343554B2 (pt)
EP (1) EP1648484B1 (pt)
JP (1) JP2007513051A (pt)
KR (2) KR101119418B1 (pt)
CN (1) CN1812802A (pt)
AT (1) ATE414526T1 (pt)
AU (1) AU2004253242B2 (pt)
BR (1) BRPI0411895B1 (pt)
CA (1) CA2530494C (pt)
DE (1) DE602004017871D1 (pt)
DK (1) DK1648484T3 (pt)
ES (1) ES2315662T3 (pt)
IL (1) IL172773A (pt)
IT (1) ITMI20031311A1 (pt)
NO (1) NO333877B1 (pt)
NZ (1) NZ544400A (pt)
PL (1) PL1648484T3 (pt)
PT (1) PT1648484E (pt)
RU (1) RU2349336C2 (pt)
SI (1) SI1648484T1 (pt)
WO (1) WO2005002611A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20040439A1 (it) * 2004-09-16 2004-12-16 Ca Di Group S R L Prodotto con azione antinfiammatoria selettiva e azione contro la fibrogenesi tissutale.
ITMI20051349A1 (it) * 2005-07-14 2007-01-15 Indena Spa Estratto di salice uso e formulazioni che lo contengono
CN100417415C (zh) * 2006-06-28 2008-09-10 文彦春 浸润治疗关节炎的药物
EP1886712A1 (en) * 2006-08-08 2008-02-13 Indena S.P.A. Compositions for the treatment of chronic degenerative inflammatory conditions
FR2907339B1 (fr) * 2006-10-20 2009-04-24 Inneov Lab Composition comprenant de la glucosamine et au moins un polyphenol.
CN101371823B (zh) * 2007-03-19 2010-09-15 上海慈瑞医药科技有限公司 二乙酰大黄酸缓释胶囊的制备工艺
FR2918376B1 (fr) 2007-07-04 2011-10-28 Mathieu Borge Compositions liquides ou pateuses destinees a l'apport en elements essentiels a la synthese et a la constitution des proteoglycanes, notamment pour le traitement de la degradation du cartilage
US20100173028A1 (en) * 2007-09-04 2010-07-08 Jun-Ki Min Process for preparing vitis vinifera pip extract and pharmaceutical composition for preventing or treating rheumatoid arthritis comprising the same
KR101682512B1 (ko) 2008-09-15 2016-12-05 라일라 뉴트라슈티칼스 보스웰리아 세라타 추출물을 포함하는 상승적인 항-염증 조성물
KR101096574B1 (ko) * 2008-12-12 2011-12-20 에이치 엘 지노믹스(주) 유럽종 포도의 씨 추출물을 함유하는 골다공증 예방 또는 치료용 약학 조성물
KR101099021B1 (ko) * 2009-04-24 2011-12-28 에이치 엘 지노믹스(주) 유럽종 포도의 씨 추출물을 함유하는 골관절염 예방 또는 치료용 약학 조성물
JP5734578B2 (ja) * 2009-09-03 2015-06-17 ナガセケムテックス株式会社 ヒアルロン酸増量剤
EP2515693A1 (en) * 2009-12-23 2012-10-31 Bae Systems Aerospace And Defense Group, INC. Quick release buckle with dual release
JP2013519664A (ja) 2010-02-15 2013-05-30 ライラ ニュートラシューティカルズ 新規ボスウェリア低極性ゴム樹脂抽出物およびその相乗的組成物
US8828377B2 (en) 2010-03-15 2014-09-09 Laila Nutraceuticals Boswellia oil, its fractions and compositions for enhancing brain function
CN103889434B (zh) 2011-06-21 2017-02-15 Bvw控股公司 含有乳香酸的医疗装置
RU2476213C1 (ru) * 2012-02-15 2013-02-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия имени Н.Н. Бурденко Министерства здравоохранения и социального развития" (ГБОУ ВПО ВГМА им. Н.Н. Бурденко Минздравсоцразвития России) Способ комплексного лечения вторичного остеоартроза при ревматоидном артрите
JP6270362B2 (ja) * 2013-07-17 2018-01-31 日本水産株式会社 関節痛改善剤
JP6153436B2 (ja) * 2013-09-27 2017-06-28 小林製薬株式会社 経口組成物
US9975917B1 (en) 2017-09-20 2018-05-22 King Saud University Pentacyclic triterpenoidal derivatives
CN111110863A (zh) * 2020-01-21 2020-05-08 郑州大学 大黄酸磷脂复合物及其制备方法和应用、大黄酸磷脂复合物长循环脂质体及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3970M (pt) 1963-11-26 1966-02-28
GB1155973A (en) * 1965-06-26 1969-06-25 Ajinomoto Kk Spiroacetal Diamine Derivatives and their use as Curing Agents for Epoxy Resins
DE3347522A1 (de) * 1983-12-30 1985-07-11 Troponwerke GmbH & Co KG, 5000 Köln N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises
DE3602670A1 (de) 1986-01-29 1987-07-30 Speck Ulrich Verwendung von n-acetylglucosamin zur therapie degenerativer gelenkprozesse und verwandter erkrankungen
US5629351A (en) 1995-04-13 1997-05-13 Council Of Scientific & Industrial Research Boswellic acid compositions and preparation thereof
DE19531067A1 (de) 1995-08-23 1997-02-27 Hermann P T Prof Dr Med Ammon Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität
US5762936A (en) * 1996-09-04 1998-06-09 Biotics Research Corporation Antioxidant derived from lentil and its preparation and uses
JP4153057B2 (ja) 1997-03-10 2008-09-17 中国化薬株式会社 Ｄ−グルクロノラクトンの製造方法
US6107334A (en) * 1998-02-23 2000-08-22 Wake Forest University Dietary control of arachidonic acid metabolism
US6761903B2 (en) * 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
CA2368593A1 (en) * 1999-05-14 2000-11-23 Regents Of The University Of California Anti-inflammatory therapy for inflammatory mediated infection
JP2002153294A (ja) * 2000-11-21 2002-05-28 Hayashibara Biochem Lab Inc グルクロン酸類及び／又はｄ−グルクロノラクトンの製造方法とその用途
US6451045B1 (en) * 2001-02-22 2002-09-17 Alsius Corporation Heat exchange catheter having a helically wrapped heat exchanger
US6541045B1 (en) * 2002-01-04 2003-04-01 Nutraceutical Corporation Herbal composition and method for combating inflammation

Also Published As

Publication number Publication date
IL172773A (en) 2010-12-30
CA2530494C (en) 2013-04-30
DK1648484T3 (da) 2009-01-19
ITMI20031311A1 (it) 2004-12-28
US20060280811A1 (en) 2006-12-14
NZ544400A (en) 2009-04-30
PT1648484E (pt) 2009-01-09
IL172773A0 (en) 2006-04-10
AU2004253242B2 (en) 2010-02-18
BRPI0411895B1 (pt) 2015-11-10
ITMI20031311A0 (it) 2003-06-27
CN1812802A (zh) 2006-08-02
EP1648484B1 (en) 2008-11-19
NO20056161L (no) 2005-12-23
AU2004253242A1 (en) 2005-01-13
NO333877B1 (no) 2013-10-07
ES2315662T3 (es) 2009-04-01
CA2530494A1 (en) 2005-01-13
KR20110039400A (ko) 2011-04-15
EP1648484A1 (en) 2006-04-26
WO2005002611A1 (en) 2005-01-13
US8343554B2 (en) 2013-01-01
KR20060032147A (ko) 2006-04-14
KR101119418B1 (ko) 2012-02-22
DE602004017871D1 (de) 2009-01-02
SI1648484T1 (sl) 2009-02-28
RU2349336C2 (ru) 2009-03-20
RU2005140573A (ru) 2006-06-10
ATE414526T1 (de) 2008-12-15
JP2007513051A (ja) 2007-05-24
PL1648484T3 (pl) 2009-04-30

Similar Documents

Publication Publication Date Title
BRPI0411895A (pt) formulações para o tratamento de condições de artrite
BRPI0415397A (pt) métodos e reagentes para o tratamento de desordens imunoinflamatórias
BRPI0810848B8 (pt) água eletrolítica altamente estável com largura de meia linha de rmn reduzida
BRPI0502346A (pt) processo de tratamento cosmético para prevenir e/ou tratar as peles sensìveis e/ou secas, utilização de uma quantidade eficaz de pelo menos um microorganismo notadamente probiótico e/ou uma de suas frações e/ou um de seus metabólitos e composição cosméticas e/ou dermatológica
BR0304648A (pt) Combinação de inibidores de ciclooxigenase-2 e talidomida para o tratamento de neoplasia
BR9913288A (pt) Composição antioxidante compreendendo acetil l-carnitina e ácido alfa-lipóico
MXPA04001876A (es) Uso de fucanos en el tratamiento de adhesiones, artritis y psoriasis.
BR9707438A (pt) Esterilizador quìmico de ação rápida.
BR9906287A (pt) Bactéria pertencente ao gênero escherichia e que tem uma capacidade para produzir um l-aminoácido, e, processo para produzir um l-aminoácido
BR0001468A (pt) ácidos dioxiciclopentil hidroxânicos
BR9809819A (pt) Compostos e métodos para a inibição da expressão de vcam-1
BRPI0510761A (pt) métodos de tratar um paciente afligido com pelo menos uma enfermidade e de reduzir ou eliminar rugas
BRPI0509140A (pt) processos para o tratamento de infecção por hiv
CY1107688T1 (el) Δικυκλικες ενωσεις πυρρολιδινης
CY1108633T1 (el) Κοσμητικη συνθεση βασεως σουκραλφατ και θειικων αλατων χαλκου και ψευδαργυρου
PT1243262E (pt) Nova utilizacao de uma classe de compostos peptideos para o tratamento da dor inflamatoria nao neuropatica
WO2000074662A3 (en) Arthritis treatment
DE60327557D1 (de) Verwendung von spongosin (2-methoxyadenosin) zur behandlung von schmerzen, insbesondere hyperalgesie
BR9712141A (pt) Aplicação de 1-hifróxi-2-piridonas para tratamento de infecções cutâneas.
BR9805318A (pt) Método para tratamento de infecções dos olhos com azitromicina.
BRPI0411176A (pt) combinação farmacêutica consistindo de modafinil e outra droga
BR0211977A (pt) Uso de sulfato de condroitina e um inibidor seletivo de cicloxigenase-2, composição farmacêutica e kit
BR9906998A (pt) Método e composições para reduzir o envelhecimento dermatológico e para reduzir contusões
BR0211830A (pt) Dose única de azitromicina
PE103799A1 (es) Procedimiento de purificacion de mesilato de alatrofloxacino

Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: A61K 36/324 (2010.01), A61P 29/00 (2010.01), A61K

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/11/2015, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 16A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2594 DE 24-09-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.