BRPI0408680A - processo para produzir álcoois e aminas enantiomericamente enriquecidos - Google Patents
processo para produzir álcoois e aminas enantiomericamente enriquecidosInfo
- Publication number
- BRPI0408680A BRPI0408680A BRPI0408680-5A BRPI0408680A BRPI0408680A BR PI0408680 A BRPI0408680 A BR PI0408680A BR PI0408680 A BRPI0408680 A BR PI0408680A BR PI0408680 A BRPI0408680 A BR PI0408680A
- Authority
- BR
- Brazil
- Prior art keywords
- amines
- enantiomerically enriched
- producing enantiomerically
- enriched alcohols
- alcohols
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
- B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1786—Unsaturated ethers containing hydroxy or O-metal groups containing halogen
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/60—Reduction reactions, e.g. hydrogenation
- B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
- B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
- B01J2231/643—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of R2C=O or R2C=NR (R= C, H)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/821—Ruthenium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/28—Hydrogenated naphthalenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
Abstract
"PROCESSO PARA PRODUZIR áLCOOIS E AMINAS ENANTIOMERICAMENTE ENRIQUECIDOS". A presente invenção refere-se a um método conveniente para a preparação e utilização de um catalisador de rutênio para uma redução quiral de cetonas e iminas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45779103P | 2003-03-26 | 2003-03-26 | |
US45803503P | 2003-03-27 | 2003-03-27 | |
PCT/IB2004/000900 WO2004085058A1 (en) | 2003-03-26 | 2004-03-15 | Process to produce enantiomerically enriched alcohols and amines |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0408680A true BRPI0408680A (pt) | 2006-03-28 |
Family
ID=33101298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0408680-5A BRPI0408680A (pt) | 2003-03-26 | 2004-03-15 | processo para produzir álcoois e aminas enantiomericamente enriquecidos |
Country Status (8)
Country | Link |
---|---|
US (1) | US7045646B2 (pt) |
JP (1) | JP2006521201A (pt) |
AR (1) | AR043771A1 (pt) |
BR (1) | BRPI0408680A (pt) |
CA (1) | CA2520030A1 (pt) |
MX (1) | MXPA05010316A (pt) |
TW (1) | TW200510283A (pt) |
WO (1) | WO2004085058A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2520030A1 (en) | 2003-03-26 | 2004-10-07 | Pharmacia & Upjohn Company Llc | Process to produce enantiomerically enriched alcohols and amines |
GB0425320D0 (en) * | 2004-11-17 | 2004-12-22 | Johnson Matthey Plc | Diamines |
ATE493416T1 (de) * | 2007-05-04 | 2011-01-15 | Mallinckrodt Inc | Verbessertes verfahren zur herstellung von 6- alpha-hydroxy-n-alkylierten opiaten |
NZ582668A (en) * | 2007-07-17 | 2012-02-24 | Mallinckrodt Llc | Preparation of n-alkylated opiates by reductive amination |
PL2340253T3 (pl) | 2008-09-30 | 2014-04-30 | SpecGx LLC | Sposoby selektywnego aminowania ketomorfinanów |
US8946419B2 (en) | 2009-02-23 | 2015-02-03 | Mallinckrodt Llc | (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives |
ES2465066T3 (es) | 2009-06-11 | 2014-06-05 | Mallinckrodt Llc | Aminación reductora de 6-ceto-normorfinanos por transferencia de hidrógeno catalítica |
PL2440562T3 (pl) | 2009-06-11 | 2017-07-31 | Mallinckrodt Llc | Otrzymywanie 6-alfa-amino-N-podstawionych morfinanów w wyniku katalitycznego przeniesienia wodoru |
RU2013157298A (ru) | 2011-06-09 | 2015-07-20 | МАЛЛИНКРОДТ Эл-Эл-Си | Восстановительное аминирование 6-кетоморфинанов посредством каталитического переноса водорода |
JO3192B1 (ar) * | 2011-09-06 | 2018-03-08 | Novartis Ag | مركب بنزوثيازولون |
RU2014112493A (ru) | 2011-09-08 | 2015-10-20 | МАЛЛИНКРОДТ Эл-Эл-Си | Получения алкалоидов без выделения промежуточных продуктов |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0218675D0 (en) * | 2002-08-12 | 2002-09-18 | Ici Plc | Nitrogen-containing ligands |
CA2520030A1 (en) | 2003-03-26 | 2004-10-07 | Pharmacia & Upjohn Company Llc | Process to produce enantiomerically enriched alcohols and amines |
-
2004
- 2004-03-15 CA CA002520030A patent/CA2520030A1/en not_active Abandoned
- 2004-03-15 BR BRPI0408680-5A patent/BRPI0408680A/pt not_active Application Discontinuation
- 2004-03-15 MX MXPA05010316A patent/MXPA05010316A/es not_active Application Discontinuation
- 2004-03-15 JP JP2006506386A patent/JP2006521201A/ja active Pending
- 2004-03-15 WO PCT/IB2004/000900 patent/WO2004085058A1/en active Application Filing
- 2004-03-19 US US10/804,295 patent/US7045646B2/en not_active Expired - Fee Related
- 2004-03-23 TW TW093107781A patent/TW200510283A/zh unknown
- 2004-03-24 AR ARP040100980A patent/AR043771A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US7045646B2 (en) | 2006-05-16 |
US20040230081A1 (en) | 2004-11-18 |
MXPA05010316A (es) | 2005-11-17 |
AR043771A1 (es) | 2005-08-10 |
WO2004085058A1 (en) | 2004-10-07 |
CA2520030A1 (en) | 2004-10-07 |
TW200510283A (en) | 2005-03-16 |
JP2006521201A (ja) | 2006-09-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0204307A2 (hu) | Pregabalin aszimmetrikus szintézise | |
UY28851A1 (es) | Bioconversión estereoselectiva de dinitrilos alifáticos en ácidos cianocarboxílicos | |
BRPI0408680A (pt) | processo para produzir álcoois e aminas enantiomericamente enriquecidos | |
EA200800908A1 (ru) | Получение прегабалина и родственных соединений | |
ATE546586T1 (de) | Verbesserte krepphilfsmittel modifizierer und verfahren zur herstellung von papierprodukten | |
ATE445587T1 (de) | Verfahren zur herstellung von cinacalcet hydrochlorid kristallform i | |
EA201170240A1 (ru) | Новые замещенные производные сульфамидов | |
DE602005018532D1 (de) | Verfahren zur permanenten formung von haar mit einem kationischen zellulosederivat | |
ATE279388T1 (de) | Verfahren zur herstellung enantiomerenangereicherter beta-aminosäure | |
ATE353869T1 (de) | Verfahren zur herstellung von 3-aminomethyl-3,5,5-trimethylcyclohexylamin | |
ATE312809T1 (de) | Verfahren zur herstellung von gabapentin | |
DE60101575D1 (de) | Verfahren zur herstellung von pharmazeutisch annehmbaren salzen des (ss,rs)-s-adenosyl-l-menthionin | |
ATE395326T1 (de) | Verfahren zur herstellung von (7-methoxy-1- naphthyl) acetonitril und dessen anwendung in der synthese von agomelatin | |
DE602005018358D1 (de) | Verfahren zur verminderung der talgproduktion und porengrösse | |
ATE543818T1 (de) | -n(2-hydroxyethyl)-n-methyl-4-(chinolin-8-yl-(1 (thiazol-4-ylmethyl)piperidin-4- yliden)methyl)benzamid, verfahren zu dessen herstellung sowie dessen verwendung zur behandlung von schmerzen, angst und depression | |
ATE488492T1 (de) | Verfahren zur herstellung von gabapentin | |
ATE337796T1 (de) | Verfahren zur herstellung von hyperpolarisiertem 129xe | |
DE602005017073D1 (de) | Verfahren zur herstellung von s)-(+)-10,11-dihydro-10-hydroxy-5h-dibenzäb,füazepin-5-carboxamid | |
ATE549315T1 (de) | Verfahren zur herstellung von kristallinem perindopril | |
ATE252543T1 (de) | Verfahren zur herstellung chiraler (s)-2,3- disubstituierter 1-propylamin-derivate | |
BRPI0414377A (pt) | processo para a sìntese de 6-amino-4-(3-cloro-4-flúor-fenilamino)-7-etóxi-quinoli na-3-carbonitrila | |
DE502005005620D1 (de) | Verfahren zur herstellung einer lösung, zugehörige anordnung sowie anwendungen des verfahrens und der anordnung | |
ATE341558T1 (de) | Verfahren zur herstellung von topiramate | |
ATE541032T1 (de) | Verfahren zur herstellung und anwendung von protozoenkulturen | |
ATE315030T1 (de) | Verfahren zur herstellung von racemischen und enantiomerenreinen derivaten von 1,5-diaryl-3- trifluormethyl-delta2-pyrazolinen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |