BRPI0408437A - derivados de p-diaminobenzeno substituìdos, composição farmacêutica, e, uso da mesma - Google Patents

derivados de p-diaminobenzeno substituìdos, composição farmacêutica, e, uso da mesma

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Publication number
BRPI0408437A
BRPI0408437A BRPI0408437-3A BRPI0408437A BRPI0408437A BR PI0408437 A BRPI0408437 A BR PI0408437A BR PI0408437 A BRPI0408437 A BR PI0408437A BR PI0408437 A BRPI0408437 A BR PI0408437A
Authority
BR
Brazil
Prior art keywords
substituted
pharmaceutical composition
diaminobenzene derivatives
derivatives
diaminobenzene
Prior art date
Application number
BRPI0408437-3A
Other languages
English (en)
Inventor
Nikolay Khanzhin
Mario Rottlonder
Ritz N Andreas
William Patrick Watson
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of BRPI0408437A publication Critical patent/BRPI0408437A/pt

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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
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    • C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
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    • C07C217/86—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
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    • C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
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    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
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Abstract

"DERIVADOS DE p-DIAMINOBENZENO SUBSTITUìDOS, COMPOSIçãO FARMACêUTICA, E, USO DA MESMA". A presente invenção refere-se aos derivados de anilina de fórmula geral I ou aos seus sais farmaceuticamente aceitáveis e ao seu uso.
BRPI0408437-3A 2003-03-21 2004-03-18 derivados de p-diaminobenzeno substituìdos, composição farmacêutica, e, uso da mesma BRPI0408437A (pt)

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US45669803P 2003-03-21 2003-03-21
DKPA200300441 2003-03-21
PCT/DK2004/000186 WO2004082677A1 (en) 2003-03-21 2004-03-18 Substituted p-diaminobenzene derivatives

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JP5615700B2 (ja) * 2007-05-25 2014-10-29 アボット ゲーエムベーハー ウント カンパニー カーゲー 代謝型グルタミン酸受容体２（ｍｇｌｕ２受容体）の陽性調節剤としての複素環化合物
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EP2398764B1 (de) 2009-02-19 2014-11-26 Basf Se Verfahren zur herstellung von 2-aminobiphenylen
CN103073455B (zh) * 2011-10-25 2015-08-19 中国科学院上海药物研究所 一类新型的kcnq钾通道激动剂、其制备方法和用途
AU2013240219A1 (en) * 2012-03-28 2014-10-09 Neuropore Therapies, Inc. Phenyl-urea and phenyl-carbamate derivatives as inhibitors of protein aggregation
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CO5700734A2 (es) 2006-11-30
MXPA05010000A (es) 2005-11-17
WO2004082677A1 (en) 2004-09-30
NO20054848L (no) 2005-10-20
AU2004222626B2 (en) 2010-06-24
EP1613303A1 (en) 2006-01-11
SG157231A1 (en) 2009-12-29
AU2004222626A1 (en) 2004-09-30

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