BRPI0211200B8 - peptídeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células - Google Patents
peptídeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de célulasInfo
- Publication number
- BRPI0211200B8 BRPI0211200B8 BRPI0211200A BRPI0211200A BRPI0211200B8 BR PI0211200 B8 BRPI0211200 B8 BR PI0211200B8 BR PI0211200 A BRPI0211200 A BR PI0211200A BR PI0211200 A BRPI0211200 A BR PI0211200A BR PI0211200 B8 BRPI0211200 B8 BR PI0211200B8
- Authority
- BR
- Brazil
- Prior art keywords
- destruction
- removal
- cells
- tumors
- require
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
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- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
"peptídeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células". a presente invenção é relacionada a peptídeos, composições e a métodos de tratamento de condições que requerem remoção ou destruição de células danosas ou indesejadas em um paciente, tal como tumores benignos e malignos, utilizando proteínas (e peptídeos derivados de seqüência de amino ácidos de tais proteínas), as seqüências de amino ácidos as quais incluem pelo menos uma sequência de amino ácido derivada de proteínas em cadeia neural e outras moléculas relacionadas.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30616101P | 2001-07-19 | 2001-07-19 | |
US30615001P | 2001-07-19 | 2001-07-19 | |
US60/306,161 | 2001-07-19 | ||
US60/306,150 | 2001-07-19 | ||
US33147701P | 2001-11-16 | 2001-11-16 | |
US60/331,477 | 2001-11-16 | ||
PCT/CA2002/001106 WO2003008444A2 (en) | 2001-07-19 | 2002-07-19 | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0211200A BR0211200A (pt) | 2004-09-28 |
BRPI0211200B1 BRPI0211200B1 (pt) | 2020-03-17 |
BRPI0211200B8 true BRPI0211200B8 (pt) | 2021-07-27 |
Family
ID=27405149
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0211200A BRPI0211200B8 (pt) | 2001-07-19 | 2002-07-19 | peptídeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células |
BR0211199-3A BR0211199A (pt) | 2001-07-19 | 2002-07-19 | Peptìdeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0211199-3A BR0211199A (pt) | 2001-07-19 | 2002-07-19 | Peptìdeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células |
Country Status (22)
Country | Link |
---|---|
US (2) | US7192929B2 (pt) |
EP (2) | EP1417228B1 (pt) |
JP (4) | JP4587667B2 (pt) |
KR (2) | KR101005130B1 (pt) |
CN (1) | CN100475843C (pt) |
AT (1) | ATE353914T1 (pt) |
AU (2) | AU2002319050B2 (pt) |
BR (2) | BRPI0211200B8 (pt) |
CA (2) | CA2453967C (pt) |
CY (1) | CY1108009T1 (pt) |
DE (2) | DE60218179T2 (pt) |
DK (1) | DK1417228T3 (pt) |
EA (1) | EA006603B1 (pt) |
ES (2) | ES2281529T3 (pt) |
IL (2) | IL159903A0 (pt) |
MX (1) | MXPA04000561A (pt) |
NO (1) | NO333999B1 (pt) |
NZ (2) | NZ531115A (pt) |
PL (1) | PL207588B1 (pt) |
PT (1) | PT1417228E (pt) |
WO (2) | WO2003008443A2 (pt) |
ZA (1) | ZA200401320B (pt) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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US20050245451A1 (en) * | 2000-04-05 | 2005-11-03 | Pincus Matthew R | Peptides selectively lethal to malignant and transformed mammalian cells |
CA2439757A1 (en) * | 2001-03-08 | 2002-09-26 | Nymox Pharmaceutical Corporation | Methods of using neural thread proteins to treat tumors and other conditions requiring the removal or destruction of cells |
US7271240B2 (en) | 2001-03-14 | 2007-09-18 | Agensys, Inc. | 125P5C8: a tissue specific protein highly expressed in various cancers |
IL159903A0 (en) * | 2001-07-19 | 2004-06-20 | Nymox Corp | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
US7317077B2 (en) * | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
DE60234047D1 (de) * | 2001-12-04 | 2009-11-26 | Millenium Pharmaceuticals Inc | 15603, ein mitglied der humanen ionenkanal-familie |
EP1646648A2 (en) * | 2003-07-15 | 2006-04-19 | Genova Ltd. | Secreted polypeptide species reduced in cardiovascular disorders |
BRPI0412664A (pt) * | 2003-07-15 | 2006-09-26 | Ca Nat Research Council | método para tratar uma condição caracterizada por hiperproliferação de células da pele em um indivìduo em risco ou portador dessa condição e utilização de uma quantidade terapeuticamente efetiva de um análogo cìclico de hormÈnio de paratireóide humano (hpth) |
WO2005075647A1 (en) * | 2004-02-06 | 2005-08-18 | Nymox Corporation | Humanized antibody |
US20060173490A1 (en) | 2005-02-01 | 2006-08-03 | Boston Scientific Scimed, Inc. | Filter system and method |
JP2009528298A (ja) | 2006-02-28 | 2009-08-06 | ナイモックス コーポレーション | 細胞の除去または破壊を必要とする腫瘍および他の状態の治療に有効なペプチド |
WO2007104149A1 (en) * | 2006-03-10 | 2007-09-20 | Nymox Corporation | Method of preventing or reducing the risk or incidence of cancer using neural thread protein based peptides |
US20080027005A1 (en) * | 2006-07-31 | 2008-01-31 | Paul Averback | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
ES2824684T3 (es) * | 2007-10-25 | 2021-05-13 | Toray Industries | Inductor de la respuesta inmunitaria |
JP5572938B2 (ja) * | 2007-10-25 | 2014-08-20 | 東レ株式会社 | 免疫誘導剤 |
US9539327B2 (en) * | 2007-11-26 | 2017-01-10 | The Research Foundation For The State University Of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
US9662370B2 (en) * | 2008-04-24 | 2017-05-30 | Therimunex Pharmaceuticals, Inc. | Peptidyl diacylglycerides |
EP2621526B1 (en) | 2010-09-29 | 2018-06-06 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
RU2016117275A (ru) | 2013-11-01 | 2017-12-04 | Сфериум Биомед С.Л. | Тельца включения для трансдермальной доставки терапевтических и косметических средств |
US20160215031A1 (en) * | 2015-01-27 | 2016-07-28 | Nymox Pharnaceutical Corporation | Method of treating disorders requiring destruction or removal of cells |
US20160361380A1 (en) | 2015-06-12 | 2016-12-15 | Nymox Corporation | Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations |
US11628202B2 (en) | 2015-07-24 | 2023-04-18 | Nymox Corporation | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia |
US10183058B2 (en) * | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
US10172910B2 (en) * | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
US10835538B2 (en) | 2018-03-28 | 2020-11-17 | Nymox Corporation | Method of treating benign prostatic hyperlasia with antibiotics |
US20200061150A1 (en) | 2018-08-23 | 2020-02-27 | Nymox Corporation | Method of inducing selective prostate glandular pharmaco-ablation with sparing of nerves and preservation of sexual function |
US11278588B2 (en) | 2019-05-13 | 2022-03-22 | Nymox Corporation | Method of treating lower urinary tract symptoms with fexapotide triflutate |
US20200360466A1 (en) | 2019-05-13 | 2020-11-19 | Nymox Corporation | Method of improving lower urinary tract symptoms |
US11298400B2 (en) | 2019-05-13 | 2022-04-12 | Nymox Corporation | Method of enhancing the therapeutic efficacy of fexapotide triflutate in treating LUTS |
US11231421B2 (en) | 2019-07-31 | 2022-01-25 | Nymox Corporation | Methods of treating multifocal cancer |
US11331374B2 (en) | 2019-07-31 | 2022-05-17 | Nymox Corporation | Focal treatment of prostate cancer |
Family Cites Families (18)
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US5948634A (en) * | 1988-12-21 | 1999-09-07 | The General Hospital Coporation | Neural thread protein gene expression and detection of alzheimer's disease |
AU4837990A (en) * | 1988-12-21 | 1990-07-10 | General Hospital Corporation, The | Method of detecting neurological disease or dysfunction |
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