BR9907997A - Specific pollen promoter - Google Patents

Specific pollen promoter

Info

Publication number
BR9907997A
BR9907997A BR9907997-6A BR9907997A BR9907997A BR 9907997 A BR9907997 A BR 9907997A BR 9907997 A BR9907997 A BR 9907997A BR 9907997 A BR9907997 A BR 9907997A
Authority
BR
Brazil
Prior art keywords
promoter
pollen
nucleic acid
well
transformation
Prior art date
Application number
BR9907997-6A
Other languages
Portuguese (pt)
Inventor
Andrew James Greenland
Hilary Joan Rogers
Patrick Joseph Hussey
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9803661.9A external-priority patent/GB9803661D0/en
Priority claimed from GBGB9803660.1A external-priority patent/GB9803660D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of BR9907997A publication Critical patent/BR9907997A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8222Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
    • C12N15/823Reproductive tissue-specific promoters
    • C12N15/8231Male-specific, e.g. anther, tapetum, pollen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237Externally regulated expression systems
    • C12N15/8238Externally regulated expression systems chemically inducible, e.g. tetracycline
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C12N15/8289Male sterility

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"PROMOTOR ESPECìFICO DE PóLEN" Um ácido nucléico recombinante que compreende uma seq³ência promotora do gene ZmC5 em milho, ou uma sua variante ou fragmento, que atua como como um promotor em pólen. A seq³ência de DNA do promotor é mostrada na Figura 5. Cassetes de expressão e sistemas de expressão assim como processos de transformação, plantas transformadas incluindo a seq³ência promotora da invenção também são reivindicados. O ácido nucléico pode ser usado inter alia na produção de plantas estéreis machos e/ou híbridos assim como na transformação de pólen."PóLEN-SPECIFIC PROMOTOR" A recombinant nucleic acid comprising a promoter sequence of the ZmC5 gene in maize, or a variant or fragment thereof, which acts as a pollen promoter. The DNA sequence of the promoter is shown in Figure 5. Expression cassettes and expression systems as well as transformation processes, transformed plants including the promoter sequence of the invention are also claimed. Nucleic acid can be used inter alia in the production of sterile male and / or hybrid plants as well as in the transformation of pollen.

BR9907997-6A 1998-02-20 1999-01-22 Specific pollen promoter BR9907997A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9803661.9A GB9803661D0 (en) 1998-02-20 1998-02-20 Pollen specific promoter
GBGB9803660.1A GB9803660D0 (en) 1998-02-20 1998-02-20 Expression system
PCT/GB1999/000232 WO1999042587A1 (en) 1998-02-20 1999-01-22 Pollen specific promoter

Publications (1)

Publication Number Publication Date
BR9907997A true BR9907997A (en) 2000-10-24

Family

ID=26313163

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907997-6A BR9907997A (en) 1998-02-20 1999-01-22 Specific pollen promoter

Country Status (11)

Country Link
EP (1) EP1054970A1 (en)
JP (1) JP2002504335A (en)
KR (1) KR20010041129A (en)
CN (1) CN1301300A (en)
AU (1) AU751438B2 (en)
BR (1) BR9907997A (en)
CA (1) CA2319079A1 (en)
DZ (1) DZ2725A1 (en)
HU (1) HUP0100787A3 (en)
IL (1) IL137971A0 (en)
WO (1) WO1999042587A1 (en)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774282B1 (en) 1999-03-08 2004-08-10 Pioneer Hi-Bred International, Inc. Maize metallothionein gene and promoter
AU2002315526A1 (en) 2001-07-06 2003-01-21 Monsanto Technology Llc Methods for enhancing segregation of transgenes in plants and compositions thereof
US7205454B2 (en) * 2002-07-31 2007-04-17 Bayer Bioscience N.V. Corn root preferential promoters and uses thereof
KR100537955B1 (en) * 2003-10-29 2005-12-20 학교법인고려중앙학원 A solely pollen-specific promoter
US7667097B2 (en) 2004-04-14 2010-02-23 Bayer Bioscience N.V. Rice pollen-preferential promoters and uses thereof
NZ600546A (en) 2010-01-22 2014-08-29 Dow Agrosciences Llc Excision of transgenes in genetically modified organisms
CN102010864B (en) * 2010-12-14 2012-10-17 安徽农业大学 Maize pollen tissue specific promoter and expression vector thereof
CN102533761B (en) * 2011-12-12 2013-03-20 华中科技大学 Pollen-specific promoter and expression vector and application thereof
CN104219950B (en) 2012-02-01 2018-02-06 陶氏益农公司 Chloroplast transit peptides derived from artificial Btassica
RU2662672C2 (en) 2012-02-02 2018-07-26 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Pesticide compositions and related methods
CA2867377A1 (en) 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
EA201491670A1 (en) * 2012-03-13 2015-07-30 Пайонир Хай-Бред Интернэшнл, Инк. GENETIC REDUCTION OF MALE REPRODUCTIVE FUNCTION IN PLANTS
EP2825656A1 (en) 2012-03-13 2015-01-21 Pioneer Hi-Bred International Inc. Genetic reduction of male fertility in plants
AU2013205557B2 (en) 2012-04-17 2016-04-21 Corteva Agriscience Llc Synthetic brassica-derived chloroplast transit peptides
CA2884162C (en) 2012-09-07 2020-12-29 Dow Agrosciences Llc Fad3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
CN102864166B (en) * 2012-09-07 2014-04-09 江苏大学 Specific expression method of beta-D-glucuronidase gene on stigma and torus of plant
UA118090C2 (en) 2012-09-07 2018-11-26 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Fad2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
JP6385644B2 (en) * 2013-03-13 2018-09-05 静岡県公立大学法人 Optical switch construct for expressing the target gene
CN104837334B (en) * 2013-05-23 2017-06-23 深圳市作物分子设计育种研究院 The new maintainer of plant and sterile line foundation and application thereof
CN109593778A (en) * 2018-11-08 2019-04-09 浙江大学 A kind of plant artificial intelligence male sterile line and application
CN110093354B (en) * 2019-04-17 2020-06-05 湖南杂交水稻研究中心 Seed sorting method for fixing plant heterosis
CA3160186A1 (en) 2019-11-05 2021-05-14 Pairwise Plants Services, Inc. Compositions and methods for rna-encoded dna-replacement of alleles
WO2021113788A1 (en) 2019-12-06 2021-06-10 Pairwise Plants Services, Inc. Recruitment methods and compounds, compositions and systems for recruitment
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AU2021212189A1 (en) 2020-01-30 2022-08-04 Pairwise Plants Services, Inc. Compositions, systems, and methods for base diversification
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WO2021168288A1 (en) 2020-02-21 2021-08-26 Pairwise Plants Services, Inc. Improved resistance to soybean cyst nematode through gene editing
WO2021188526A1 (en) 2020-03-16 2021-09-23 Pairwise Plants Services, Inc. Natural guide architectures and methods of making and using the same
US11999946B2 (en) 2020-03-26 2024-06-04 Pairwise Plants Services, Inc. Methods for controlling meristem size for crop improvement
US11882808B2 (en) 2020-03-27 2024-01-30 Pairwise Plants Services, Inc. Methods for improving resistance to soybean rust
US20230175006A1 (en) 2020-04-06 2023-06-08 Pairwise Plants Services, Inc. Methods and compositions for increasing resistance to ear rot and stem rot disease in maize
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WO2022006226A1 (en) 2020-06-30 2022-01-06 Pairwise Plants Services, Inc. Compositions, systems, and methods for base diversification
WO2022047135A1 (en) 2020-08-28 2022-03-03 Pairwise Plants Services, Inc. Engineered crispr-cas proteins and methods of use thereof
JP2023549339A (en) 2020-11-06 2023-11-24 ペアワイズ・プランツ・サーヴィシズ,インコーポレイテッド Compositions and methods for allelic, RNA-encoded DNA replacement
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US20220403475A1 (en) 2021-06-14 2022-12-22 Pairwise Plants Services, Inc. Reporter constructs, compositions comprising the same, and methods of use thereof
CN117897050A (en) 2021-06-17 2024-04-16 成对植物服务股份有限公司 Modification of growth regulator family transcription factors in soybean
UY39827A (en) 2021-06-24 2023-01-31 Pairwise Plants Services Inc MODIFICATION OF UBIQUITIN LIGASE E3 HECT GENES TO IMPROVE PERFORMANCE TRAITS
WO2023278651A1 (en) 2021-07-01 2023-01-05 Pairwise Plants Services, Inc. Methods and compositions for enhancing root system development
US20230078990A1 (en) 2021-08-12 2023-03-16 Pairwise Plants Services, Inc. Modification of brassinosteroid receptor genes to improve yield traits
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US20230074699A1 (en) 2021-08-30 2023-03-09 Pairwise Plants Services, Inc. Modification of ubiquitin binding peptidase genes in plants for yield trait improvement
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AU2022352997A1 (en) 2021-09-21 2024-04-04 Pairwise Plants Services, Inc. Methods and compositions for reducing pod shatter in canola
WO2023049728A1 (en) 2021-09-21 2023-03-30 Pairwise Plants Services, Inc. Color-based and/or visual methods for identifying the presence of a transgene and compositions and constructs relating to the same
US20230108968A1 (en) 2021-10-04 2023-04-06 Pairwise Plants Services, Inc. Methods for improving floret fertility and seed yield
US20230116819A1 (en) 2021-10-07 2023-04-13 Pairwise Plants Services, Inc. Methods for improving floret fertility and seed yield
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WO2023114750A1 (en) 2021-12-13 2023-06-22 Pairwise Plants Services, Inc. Model editing systems and methods relating to the same
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US20230383271A1 (en) 2022-02-28 2023-11-30 Pairwise Plants Services, Inc. Engineered proteins and methods of use thereof
WO2023168217A1 (en) 2022-03-02 2023-09-07 Pairwise Plants Services, Inc. Modification of brassinosteroid receptor genes to improve yield traits
WO2023192838A1 (en) 2022-03-31 2023-10-05 Pairwise Plants Services, Inc. Early flowering rosaceae plants with improved characteristics
US20230357789A1 (en) 2022-04-07 2023-11-09 Pairwise Plants Services, Inc. Methods and compositions for improving resistance to fusarium head blight
WO2023205714A1 (en) 2022-04-21 2023-10-26 Pairwise Plants Services, Inc. Methods and compositions for improving yield traits
WO2023215704A1 (en) 2022-05-02 2023-11-09 Pairwise Plants Services, Inc. Methods and compositions for enhancing yield and disease resistance
WO2023215809A1 (en) 2022-05-05 2023-11-09 Pairwise Plants Services, Inc. Methods and compositions for modifying root architecture and/or improving plant yield traits
US20230416771A1 (en) 2022-06-27 2023-12-28 Pairwise Plants Services, Inc. Methods and compositions for modifying shade avoidance in plants
WO2024006792A1 (en) 2022-06-29 2024-01-04 Pairwise Plants Services, Inc. Methods and compositions for controlling meristem size for crop improvement
WO2024006791A1 (en) 2022-06-29 2024-01-04 Pairwise Plants Services, Inc. Methods and compositions for controlling meristem size for crop improvement
US20240043857A1 (en) 2022-08-04 2024-02-08 Pairwise Plants Services, Inc. Methods and compositions for improving yield traits
US20240060081A1 (en) 2022-08-11 2024-02-22 Pairwise Plants Services, Inc. Methods and compositions for controlling meristem size for crop improvement
US20240090466A1 (en) 2022-09-08 2024-03-21 Pairwise Plants Services, Inc. Methods and compositions for improving yield characteristics in plants
US20240200102A1 (en) 2022-12-16 2024-06-20 Pairwise Plants Services, Inc. Fusion proteins comprising an intein polypeptide and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901677D0 (en) * 1989-01-26 1989-03-15 Ici Plc Hybrid seed production
EP0644943B1 (en) * 1992-06-12 2005-10-05 Bayer BioScience N.V. Maintenance of male-sterile plants
GB9515161D0 (en) * 1995-07-24 1995-09-20 Zeneca Ltd Production of male sterile plants
US5677175A (en) * 1995-10-13 1997-10-14 Purdue Research Foundation Plant pathogen induced proteins
GB9607517D0 (en) * 1996-04-11 1996-06-12 Gene Shears Pty Ltd The use of DNA Sequences
AU5140998A (en) * 1997-08-18 1999-03-08 Zakrytoe Aktsionernoe Obschestvo "Firma Novye Sistemnye Tekhnologii" Method of laser welding of thin sheet metallic components

Also Published As

Publication number Publication date
HUP0100787A3 (en) 2003-04-28
JP2002504335A (en) 2002-02-12
AU751438B2 (en) 2002-08-15
KR20010041129A (en) 2001-05-15
CA2319079A1 (en) 1999-08-26
AU2287699A (en) 1999-09-06
WO1999042587A1 (en) 1999-08-26
DZ2725A1 (en) 2003-09-01
IL137971A0 (en) 2001-10-31
CN1301300A (en) 2001-06-27
HUP0100787A2 (en) 2002-04-29
EP1054970A1 (en) 2000-11-29

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