BR9812970A - Derivado de tetraidropiridopirimidinona 3-substituìda, e, uso deste - Google Patents

Derivado de tetraidropiridopirimidinona 3-substituìda, e, uso deste

Info

Publication number
BR9812970A
BR9812970A BR9812970-8A BR9812970A BR9812970A BR 9812970 A BR9812970 A BR 9812970A BR 9812970 A BR9812970 A BR 9812970A BR 9812970 A BR9812970 A BR 9812970A
Authority
BR
Brazil
Prior art keywords
derivative
substituted
tetrahydropyridopyrimidinone
substituted tetrahydropyridopyrimidinone
derivatives
Prior art date
Application number
BR9812970-8A
Other languages
English (en)
Inventor
Wilfried Lubisch
Uta Dullweber
Dorothea Starck
Gerd Steiner
Alfred Bach
Franz Emling
Xavier Garcia-Ladona
Hans-J Rgen Teschendorf
Karsten Wicke
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of BR9812970A publication Critical patent/BR9812970A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Structure And Mechanism Of Cameras (AREA)

Abstract

"DERIVADO DE TETRAIDROPIRIDOPIRIMIDINONA 3-SUBSTITUìDA, E, USO DESTE" A invenção refere-se a derivados de tetraidropiridopirimidinona 3-substituída de fórmula (I), em que os radicais possuem os significados dados na Descrição, a um processo para produzir estes derivados e a seu uso como antagonistas seletivos de 5HT~ 1B~ e 5HT~ 1A~.
BR9812970-8A 1997-10-24 1998-10-05 Derivado de tetraidropiridopirimidinona 3-substituìda, e, uso deste BR9812970A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19747063A DE19747063A1 (de) 1997-10-24 1997-10-24 3-substituierte Tetrahydropyridopyrimidinon-Derivate, ihre Herstellung und Verwendung
PCT/EP1998/006305 WO1999021857A1 (de) 1997-10-24 1998-10-05 3-substituierte tetrahydropyridopyrimidinon-derivate, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
BR9812970A true BR9812970A (pt) 2000-08-08

Family

ID=7846539

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812970-8A BR9812970A (pt) 1997-10-24 1998-10-05 Derivado de tetraidropiridopirimidinona 3-substituìda, e, uso deste

Country Status (27)

Country Link
US (1) US6414157B1 (pt)
EP (1) EP1025100B1 (pt)
JP (1) JP2001521035A (pt)
KR (1) KR20010015787A (pt)
CN (1) CN1277611A (pt)
AR (1) AR015466A1 (pt)
AT (1) ATE212346T1 (pt)
AU (1) AU748666B2 (pt)
BG (1) BG104291A (pt)
BR (1) BR9812970A (pt)
CA (1) CA2305258A1 (pt)
CO (1) CO4980862A1 (pt)
DE (2) DE19747063A1 (pt)
DK (1) DK1025100T3 (pt)
ES (1) ES2172222T3 (pt)
HR (1) HRP980554A2 (pt)
HU (1) HUP0004648A3 (pt)
ID (1) ID24633A (pt)
NO (1) NO20001934L (pt)
NZ (1) NZ503486A (pt)
PL (1) PL340034A1 (pt)
PT (1) PT1025100E (pt)
SK (1) SK3872000A3 (pt)
TR (1) TR200001102T2 (pt)
TW (1) TW432063B (pt)
WO (1) WO1999021857A1 (pt)
ZA (1) ZA989664B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900544A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Verbindungen der Formel I zur Prophylaxe und Therapie der zerebralen Ischämie
WO2004014909A1 (en) * 2002-08-13 2004-02-19 Warner-Lambert Company Llc Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors
US20040127501A1 (en) * 2002-09-24 2004-07-01 Zhengming Chen Therapeutic agents useful for treating pain
JP4654035B2 (ja) 2002-11-05 2011-03-16 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
CL2004000409A1 (es) * 2003-03-03 2005-01-07 Vertex Pharma Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu
US7160888B2 (en) * 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
DE102004020908A1 (de) 2004-04-28 2005-11-17 Grünenthal GmbH Substituierte 5,6,7,8,-Tetrahydro-pyrido[4,3-d]pyrimidin-2-yl- und 5,6,7,8,-Tetrahydro-chinazolin-2-yl-Verbindungen
MX2007012083A (es) * 2005-04-01 2007-11-20 Warner Lambert Co Tetrahidro-piridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofrenia.
CN101296914B (zh) * 2005-08-26 2012-07-18 盐野义制药株式会社 具有ppar激动活性的衍生物
CN102952129B (zh) * 2011-08-16 2015-09-23 上海师范大学 四氢吡啶并二氢嘧啶酮衍生物及其制备方法和应用
WO2022087011A1 (en) 2020-10-21 2022-04-28 Aligos Therapeutics, Inc. Bicyclic compounds
US11957683B2 (en) 2021-06-18 2024-04-16 Aligos Therapeutics, Inc. Bicyclic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0827149A (ja) * 1994-07-08 1996-01-30 Meiji Seika Kaisha Ltd ピリミジノン誘導体およびその塩

Also Published As

Publication number Publication date
HUP0004648A3 (en) 2001-11-28
SK3872000A3 (en) 2000-09-12
JP2001521035A (ja) 2001-11-06
US6414157B1 (en) 2002-07-02
DK1025100T3 (da) 2002-05-06
WO1999021857A1 (de) 1999-05-06
EP1025100A1 (de) 2000-08-09
NO20001934D0 (no) 2000-04-13
CN1277611A (zh) 2000-12-20
AU748666B2 (en) 2002-06-06
ATE212346T1 (de) 2002-02-15
PT1025100E (pt) 2002-07-31
PL340034A1 (en) 2001-01-15
HRP980554A2 (en) 1999-08-31
NO20001934L (no) 2000-04-13
DE59802922D1 (de) 2002-03-14
ID24633A (id) 2000-07-27
CO4980862A1 (es) 2000-11-27
TW432063B (en) 2001-05-01
BG104291A (en) 2001-05-31
TR200001102T2 (tr) 2000-08-21
AR015466A1 (es) 2001-05-02
CA2305258A1 (en) 1999-05-06
ZA989664B (en) 2000-04-25
KR20010015787A (ko) 2001-02-26
HUP0004648A2 (hu) 2001-05-28
DE19747063A1 (de) 1999-04-29
ES2172222T3 (es) 2002-09-16
NZ503486A (en) 2001-04-27
EP1025100B1 (de) 2002-01-23
AU9748498A (en) 1999-05-17

Similar Documents

Publication Publication Date Title
BR9812970A (pt) Derivado de tetraidropiridopirimidinona 3-substituìda, e, uso deste
ES2193391T3 (es) Antagonistas muscarinicos.
ES2175741T3 (es) Nuevos derivados del acido sulfinico, su procedimiento de preparacion y su utilizacion.
ECSP034924A (es) Derivados sustituidos del 1-oxa-2,8-daza-espiro[4,5]dec-2-eno
ES2195785B1 (es) Nuevos derivados de piridazin-3(2h)-ona.
UY27760A1 (es) Nuevos derivados de pirrolidinio.
PA8481301A1 (es) Derivados de 4,4-biarilpiperidina
PT1140944E (pt) Derivados de epotilona e sua utilizacao como agentes antitumorais
ES2134755T3 (es) Derivados de quinolina como antagonistas de leucotrieno d4, composiciones que contienen los mismos y procedimientos para su preparacion.
PT896533E (pt) Pentafluorobenzenosulfonamidas e analogos
BR9911682A (pt) Metano sulfonato de paroxetina
BR0011831A (pt) Compostos, processo para preparar os mesmos, composições farmacêuticas, e, uso dos compostos
BR9909468A (pt) Composto anti-bacteriano, composição oral anti-placas, e, processo para promoção da higiene oral
BR0007864A (pt) Composto, e, uso de um composto
AR018162A1 (es) Pirroles substituidos, composicion farmaceutica y el uso de los mismos para la preparacion de dicha composicion farmaceutica
AR021843A1 (es) Derivados de propanolamina sustituidos con heterociclos, procedimiento para su preparacion, y su utilizacion.
BR9812892A (pt) 2 4-diamino-1,3,5-triazinas substituìdas e seu emprego como herbicidas
BR9713159A (pt) Composição substancialmente sólida, composto, composição de sal substancialmente sólida, mistura, e, processo para preparar um composto
AR020563A1 (es) Compuestos (poli)tia-alquinoicos y sus derivados, composiciones que los incluyen y su utilizacion
BR0114367A (pt) Processo para a preparação de um composto, e, composto
BR9714215A (pt) Derivados de benzoato de 1,4-diazabiciclo[2.2.2]oct-2-ilmetila, seu preparo e sua aplicação em terapêutica
AR001813A1 (es) Derivados de cromona procedimiento para prepararlos y las composiciones farmacéutica que los contienen
BR9914811A (pt) Processo para a preparação de derivados de quercetina e isoquercetina
BR9912138A (pt) Compostos cìclicos úteis no tratamento de dislipidemia, aterosclerose e diabetes, composções farmacêuticas e processo para preparação
BR0309130A (pt) Derivados de acil-3-carboxifenil-uréia, processo para a sua preparação e sua aplicação

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A,7AE 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.