BR9808157A - Processo de inibição do desenvolvimento de células tumorais e de tumor e composição farmacêutica - Google Patents

Processo de inibição do desenvolvimento de células tumorais e de tumor e composição farmacêutica

Info

Publication number
BR9808157A
BR9808157A BR9808157-8A BR9808157A BR9808157A BR 9808157 A BR9808157 A BR 9808157A BR 9808157 A BR9808157 A BR 9808157A BR 9808157 A BR9808157 A BR 9808157A
Authority
BR
Brazil
Prior art keywords
tumor
pharmaceutical composition
inhibition
cell development
tumor cell
Prior art date
Application number
BR9808157-8A
Other languages
English (en)
Inventor
Charles E Elson
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of BR9808157A publication Critical patent/BR9808157A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

''PROCESSO DE INIBIçãO DO DESENVOLVIMENTO DE CéLULAS TUMORAIS E DE TUMOR E COMPOSIçãO FARMACêUTICA''. Um processo para inibir o desenvolvimento de células tumorais é apresentado. Em uma modalidade, este processo compreende a etapa de expor as células tumorais a uma quantidade eficaz de uma composição compreendendo pelo menos dois compostos selecionados do grupo consistindo de tocotrienóis, estatinas e iononas.
BR9808157-8A 1997-03-04 1998-02-23 Processo de inibição do desenvolvimento de células tumorais e de tumor e composição farmacêutica BR9808157A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3979097P 1997-03-04 1997-03-04
PCT/US1998/003470 WO1998038993A1 (en) 1997-03-04 1998-02-23 Method of suppressing tumor growth with combinations of isoprenoids and statins

Publications (1)

Publication Number Publication Date
BR9808157A true BR9808157A (pt) 2000-03-28

Family

ID=21907353

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808157-8A BR9808157A (pt) 1997-03-04 1998-02-23 Processo de inibição do desenvolvimento de células tumorais e de tumor e composição farmacêutica

Country Status (13)

Country Link
US (2) US6133312A (pt)
EP (1) EP0986383A1 (pt)
JP (1) JP2001507363A (pt)
KR (1) KR20000075919A (pt)
AU (1) AU729355B2 (pt)
BR (1) BR9808157A (pt)
CA (1) CA2283333A1 (pt)
HU (1) HUP0002049A2 (pt)
IL (1) IL131628A0 (pt)
NO (1) NO994309L (pt)
PL (1) PL335506A1 (pt)
RU (1) RU2179440C2 (pt)
WO (1) WO1998038993A1 (pt)

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US6239114B1 (en) * 1997-09-26 2001-05-29 Kgk Synergize Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
US6251400B1 (en) * 1997-09-26 2001-06-26 Kgk Synergize Inc Compositions and methods of treatment of neoplastic diseases and hypercholesterolemia with citrus limonoids and flavonoids and tocotrienols
US6703384B2 (en) * 1998-09-23 2004-03-09 Research Development Foundation Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof
CA2353475A1 (en) * 1998-12-07 2000-06-15 Ecosmart Technologies, Inc. Cancer treatment composition and method using natural plant essential oils with signal transduction modulators
CN1243000C (zh) * 2000-02-11 2006-02-22 研究发展基金会 生育酚、生育三烯酚、其它苯并二氢吡喃和侧链衍生物,及其用途
US20030104090A1 (en) * 2000-05-05 2003-06-05 Levy Pedro E. Supplements containing annatto extracts and carotenoids and methods for using the same
US6566397B2 (en) 2000-07-18 2003-05-20 Wisconsin Alumni Research Foundation Acyclic isoprenoid ether derivatives as chemotherapeutics
US20030236301A1 (en) * 2001-12-19 2003-12-25 Bob Sanders Liposomal delivery of vitamin E based compounds
US7074825B2 (en) * 2002-03-07 2006-07-11 Huanbiao Mo Composition and method for treating cancer
US7989006B2 (en) * 2003-04-08 2011-08-02 American River Nutrition, Inc. Annatto extract compositions, including geranyl geraniols and methods of use
ES2712944T3 (es) * 2003-04-08 2019-05-16 Barrie Tan Composiciones de extracto de achiote, que incluyen geranilgeranioles para su uso en la reducción del nivel de triglicéridos en sangre
US20050037102A1 (en) * 2003-07-18 2005-02-17 Barrie Tan Annatto extract compositions including tocotrienols and tocopherols and methods of use
JPWO2005094814A1 (ja) * 2004-03-31 2008-02-14 興和株式会社 外用剤
ZA200610168B (en) * 2004-05-26 2008-06-25 Kgk Synergize Inc Compositions comprising flavonoids and tocotrienols and methods thereof
DE102006008074B4 (de) * 2006-02-22 2013-08-14 RUHR-UNIVERSITäT BOCHUM Behandlung von Krebs mit Geruchsrezeptor-Liganden
US8288369B2 (en) * 2006-06-27 2012-10-16 University Of South Florida Delta-tocotrienol treatment and prevention of pancreatic cancer
US20090004290A1 (en) * 2007-06-30 2009-01-01 Voelker Kirk G Red yeast rice compound for cancer chemoprevention
WO2010124223A1 (en) * 2009-04-23 2010-10-28 First Tech International Limited Anti-cancer tocotrienol analogues and associated methods
EP2473044B1 (en) * 2009-09-01 2014-04-02 First Tech International Limited Tocotrienol compositions
US8969303B2 (en) * 2010-02-05 2015-03-03 First Tech International Limited Tocotrienol esters
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
JP2016530333A (ja) 2013-09-13 2016-09-29 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー 放射線の影響から防護するため及び放射線の影響を緩和するための組成物の調製及び使用
US20160324914A1 (en) 2015-05-05 2016-11-10 Tocol Pharmaceuticals, Llc Use of rice bran oil distillate extract for prevention and mitigation of the effects of radiation

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US34617A (en) * 1862-03-04 Improved cylinder for grain scouring and thrashing machines
US33885A (en) * 1861-12-10 Improvement
USRE33885E (en) 1975-11-03 1992-04-14 The Procter & Gamble Company Compositions for inhibiting absorption of cholesterol
US4005196A (en) 1976-02-12 1977-01-25 The Procter & Gamble Company Vitaminized compositions for treating hypercholesterolemia
US4789554A (en) * 1985-12-05 1988-12-06 The Procter & Gamble Company High temperature vacuum steam distillation process to purify and increase the frylife of edible oils
AU618791B2 (en) * 1988-03-16 1992-01-09 Bioindustry Development Centre Production of high concentration tocopherols and tocotrienols from palm oil by-product
DE3903991A1 (de) * 1989-02-10 1990-08-30 Basf Ag Phenylhydrazone des (beta)-jonons, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
US5217992A (en) * 1989-10-04 1993-06-08 Bristol-Myers Squibb Company Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
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US5554647A (en) * 1989-10-12 1996-09-10 Perricone; Nicholas V. Method and compositions for treatment and/or prevention of skin damage and aging
US5157132A (en) * 1990-05-18 1992-10-20 Carotech Associates Integrated process for recovery of carotenoids and tocotrienols from oil
US5393776A (en) * 1990-09-14 1995-02-28 Bristol-Myers Squibb Company Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
US5204373A (en) * 1991-08-26 1993-04-20 Bristol-Myers Squibb Company Farnesylated tetrahydro-naphthalenols as hypolipidemic agents
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
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CA2129732A1 (en) * 1992-02-25 1993-09-02 Alain Martin Cytoprotective compositions containing pyruvate and antioxidants
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Also Published As

Publication number Publication date
NO994309D0 (no) 1999-09-03
WO1998038993A1 (en) 1998-09-11
PL335506A1 (en) 2000-04-25
US6441029B1 (en) 2002-08-27
CA2283333A1 (en) 1998-09-11
AU6335198A (en) 1998-09-22
HUP0002049A2 (hu) 2000-10-28
KR20000075919A (ko) 2000-12-26
US6133312A (en) 2000-10-17
JP2001507363A (ja) 2001-06-05
NO994309L (no) 1999-09-03
RU2179440C2 (ru) 2002-02-20
EP0986383A1 (en) 2000-03-22
AU729355B2 (en) 2001-02-01
IL131628A0 (en) 2001-01-28

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Legal Events

Date Code Title Description
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI 1891 DE 03/04/2007