BR9807916A - Conjunto de dispositivo biomédico, método para inibir substancialmente a reestenose em um vaso sanguìneo de um paciente, método para fabricar um conjunto de dispositivo biomédico. - Google Patents

Conjunto de dispositivo biomédico, método para inibir substancialmente a reestenose em um vaso sanguìneo de um paciente, método para fabricar um conjunto de dispositivo biomédico.

Info

Publication number
BR9807916A
BR9807916A BR9807916-6A BR9807916A BR9807916A BR 9807916 A BR9807916 A BR 9807916A BR 9807916 A BR9807916 A BR 9807916A BR 9807916 A BR9807916 A BR 9807916A
Authority
BR
Brazil
Prior art keywords
biomedical device
device set
stent
patient
antibody
Prior art date
Application number
BR9807916-6A
Other languages
English (en)
Inventor
Solomon Mosseri
Original Assignee
Set Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Set Ltd filed Critical Set Ltd
Publication of BR9807916A publication Critical patent/BR9807916A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6957Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a device or a kit, e.g. stents or microdevices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Radiation-Therapy Devices (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Massaging Devices (AREA)

Abstract

"CONJUNTO DE DISPOSITIVO BIOMéDICO, MéTODO PARA INIBIR SUBSTANCIALMENTE A REESTENOSE EM UM VASO SANGuìNEO DE UM PACIENTE, MéTODO PARA FABRICAR UM CONJUNTO DE DISPOSITIVO BIOMéDICO". Um conjunto de dispositivo biomédico tal como um stent, para o tratamento dirigido de um tecido, tal como a inibição da reestenose. O stent é revestido com um antígeno, que é um exemplo de bloqueio. O antígeno pode ser ligado por um anticorpo traçado, que é o exemplo de uma chave e um efetor. O anticorpo é preferivelmente traçado com uma fonte radioativa. De acordo com um método de preparar o conjunto de dispositivo biomédico depois que o stent foi colocado no vaso sang³íneo do paciente, é injetado o anticorpo. O anticorpo então se liga ao antígeno no stent, dessa maneira localizando a fonte radioativa na área a ser tratada, por exemplo contra reestenose. Outros dispositivos biomédicos, tais como uma espiral, uma válvula artificial ou um enxerto vascular também podem ser usados no lugar do stent. O dispositivo biomédico pode ser colocado em um tecido sólido tal como um tumor sólido ou outra pasagem biológica, tal como o trato gastrintestinal, as vias respiratórias ou o trato gênito-urinário.
BR9807916-6A 1997-04-01 1998-03-30 Conjunto de dispositivo biomédico, método para inibir substancialmente a reestenose em um vaso sanguìneo de um paciente, método para fabricar um conjunto de dispositivo biomédico. BR9807916A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/831,387 US5925353A (en) 1997-04-01 1997-04-01 Targeted radioimmunotherapy
PCT/IL1998/000154 WO1998043694A1 (en) 1997-04-01 1998-03-30 Targeted therapy to a biomedical device

Publications (1)

Publication Number Publication Date
BR9807916A true BR9807916A (pt) 2000-02-22

Family

ID=25258943

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9807916-6A BR9807916A (pt) 1997-04-01 1998-03-30 Conjunto de dispositivo biomédico, método para inibir substancialmente a reestenose em um vaso sanguìneo de um paciente, método para fabricar um conjunto de dispositivo biomédico.

Country Status (10)

Country Link
US (1) US5925353A (pt)
EP (1) EP0979122A1 (pt)
JP (1) JP2002501408A (pt)
AU (1) AU6744498A (pt)
BR (1) BR9807916A (pt)
CA (1) CA2285324A1 (pt)
IL (1) IL132045A0 (pt)
NO (1) NO994574L (pt)
TR (1) TR199902438T2 (pt)
WO (1) WO1998043694A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0633041T3 (da) 1993-07-01 2000-04-03 Schneider Europ Gmbh Medicinske apparater til behandling af blodkar ved hjælp af ioniserende stråling
US5857956A (en) 1994-06-08 1999-01-12 United States Surgical Corporation Flexible source wire for localized internal irradiation of tissue
ATE170708T1 (de) 1994-06-10 1998-09-15 Schneider Europ Gmbh Arzneigerät für die behandlung eines teiles von körpergefäss mittels ionisierungsbestrahlung
DE69426071T2 (de) 1994-06-24 2001-05-10 Schneider (Europe) Gmbh, Buelach Arzneigerät für die Behandlung eines Teiles eines Körpergefässes mittels Ionisierungsbestrahlung
US6234951B1 (en) 1996-02-29 2001-05-22 Scimed Life Systems, Inc. Intravascular radiation delivery system
IT1289728B1 (it) * 1996-12-10 1998-10-16 Sorin Biomedica Cardio Spa Dispositivo di impianto e corredo che lo comprende
US6238872B1 (en) * 1997-04-01 2001-05-29 S.E.T.-Smart Endolumenal Technologies Ltd. Targeted therapy to a biomedical device
WO1999009912A1 (en) * 1997-08-26 1999-03-04 Technion Research And Development Foundation Ltd. Intravascular apparatus and method
WO1999015234A1 (en) 1997-09-23 1999-04-01 United States Surgical Corporation Source wire for radiation treatment
US6264596B1 (en) * 1997-11-03 2001-07-24 Meadox Medicals, Inc. In-situ radioactive medical device
DE19853067A1 (de) * 1998-11-17 2000-05-18 Jomed Implantate Gmbh Radioaktiver Stent
US6416457B1 (en) 2000-03-09 2002-07-09 Scimed Life Systems, Inc. System and method for intravascular ionizing tandem radiation therapy
US6302865B1 (en) 2000-03-13 2001-10-16 Scimed Life Systems, Inc. Intravascular guidewire with perfusion lumen
US20030229393A1 (en) * 2001-03-15 2003-12-11 Kutryk Michael J. B. Medical device with coating that promotes cell adherence and differentiation
US20070055367A1 (en) * 2000-03-15 2007-03-08 Orbus Medical Technologies, Inc. Medical device with coating that promotes endothelial cell adherence and differentiation
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
WO2003054544A2 (de) * 2001-12-21 2003-07-03 Viscum Ag Verfahren zur bestimmung der responsivität eines individuums für mistellektin
US6918869B2 (en) 2002-12-02 2005-07-19 Scimed Life Systems System for administering a combination of therapies to a body lumen
GB2420976B (en) * 2004-11-19 2006-12-20 Zvi Finkelstein Therapeutic implant
US10219884B2 (en) 2006-07-10 2019-03-05 First Quality Hygienic, Inc. Resilient device
BRPI0714288B1 (pt) 2006-07-10 2018-06-26 Mcneil-Ppc, Inc. Dispositivo de incontinência urinária intravaginal
US8613698B2 (en) 2006-07-10 2013-12-24 Mcneil-Ppc, Inc. Resilient device
US10004584B2 (en) 2006-07-10 2018-06-26 First Quality Hygienic, Inc. Resilient intravaginal device
US8177706B2 (en) 2006-07-10 2012-05-15 Mcneil-Ppc, Inc. Method of treating urinary incontinence
ATE518504T1 (de) * 2006-12-07 2011-08-15 Mallinckrodt Inc Medizinische vorrichtungen zur lokalen arzneimittelabgabe
KR101023164B1 (ko) * 2007-06-19 2011-03-18 (주)바이오니아 화학물질로 코팅된 금도금 스텐트, 올리고뉴클레오타이드를 바인딩시킨 금도금 스텐트 및 이들의제조방법
EP2226083A4 (en) * 2007-12-25 2013-01-23 Univ Yamaguchi ACTIVE RELEASE SYSTEM
US20100305688A1 (en) * 2009-05-26 2010-12-02 Mallinckrodt Inc. Medical Devices for Localized Drug Delivery
CN112206421A (zh) * 2012-03-06 2021-01-12 天津市调序脑科学研究所 一种能对脑功能实现整体调序的调序治疗仪

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
ES2004281A6 (es) * 1986-04-04 1988-12-16 Univ Jefferson Una superficie protesica implantable para implantacion en un paciente humano
US5571166A (en) * 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
US5643712A (en) * 1994-05-20 1997-07-01 Brasile; Lauren Method for treating and rendering grafts nonthrombogenic and substantially nonimmunogenic using an extracellular matrix coating
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method

Also Published As

Publication number Publication date
CA2285324A1 (en) 1998-10-08
EP0979122A1 (en) 2000-02-16
IL132045A0 (en) 2001-03-19
WO1998043694A1 (en) 1998-10-08
US5925353A (en) 1999-07-20
JP2002501408A (ja) 2002-01-15
NO994574D0 (no) 1999-09-20
NO994574L (no) 1999-11-26
AU6744498A (en) 1998-10-22
TR199902438T2 (xx) 2000-01-21

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]