BR9807671A - Circuito analógico para um sistema de microscópio de foco automático - Google Patents

Circuito analógico para um sistema de microscópio de foco automático

Info

Publication number
BR9807671A
BR9807671A BR9807671-0A BR9807671A BR9807671A BR 9807671 A BR9807671 A BR 9807671A BR 9807671 A BR9807671 A BR 9807671A BR 9807671 A BR9807671 A BR 9807671A
Authority
BR
Brazil
Prior art keywords
focus
microscope
autofocus
real time
degree
Prior art date
Application number
BR9807671-0A
Other languages
English (en)
Inventor
Jeffrey H Price
Miguel Bravo-Zanoguera
Original Assignee
Q3Dm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Q3Dm Llc filed Critical Q3Dm Llc
Publication of BR9807671A publication Critical patent/BR9807671A/pt

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/244—Devices for focusing using image analysis techniques

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Automatic Focus Adjustment (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

Patente de Invenção: <B>"CIRCUITO ANALóGICO PARA UM SISTEMA DE MICROSCóPIO DE FOCO AUTOMáTICO"<D>. Um circuito analógico para um sistema de microscópio de foco automático mede um grau de foco de um objeto diretamente de um sinal de vídeo de uma câmera CCD de microscópio. O circuito então retorna um índice de foco para um computador hospedeiro para o propósito de ajustar a posição da lente objetiva do microscópio para trazer o objeto em foco. O melhor foco é encontrado comparando índices em diversas, diferentes posições verticais. O critério adotado para a determinação do grau de foco é derivado da distribuição de energia do espectro do sinal de vídeo. O sinal passa através de um filtro de passa alta, uma porta (para remover artefatos de exploração), um elemento de quadratura e um integrador. A energia de alta freq³ência do espectro de vídeo é um máximo no melhor foco e como a desfocagem ótica, a distribuição desloca-se para freq³ências mais baixas. é conseguido, foco automático em tempo real, de baixo custo, com o circuito analógico desta invenção, substituindo equipamento de processamento de imagem em tempo real dedicado mais caro.
BR9807671-0A 1997-02-07 1998-01-14 Circuito analógico para um sistema de microscópio de foco automático BR9807671A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/796,196 US5995143A (en) 1997-02-07 1997-02-07 Analog circuit for an autofocus microscope system
PCT/US1998/000318 WO1998035256A1 (en) 1997-02-07 1998-01-14 Analog circuit for an autofocus microscope system

Publications (1)

Publication Number Publication Date
BR9807671A true BR9807671A (pt) 2000-02-15

Family

ID=25167583

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9807671-0A BR9807671A (pt) 1997-02-07 1998-01-14 Circuito analógico para um sistema de microscópio de foco automático

Country Status (10)

Country Link
US (2) US5995143A (pt)
EP (1) EP1021741B1 (pt)
JP (1) JP2001511903A (pt)
CN (1) CN1246929A (pt)
AT (1) ATE223070T1 (pt)
AU (1) AU5909998A (pt)
BR (1) BR9807671A (pt)
CA (1) CA2283088C (pt)
DE (1) DE69807512T2 (pt)
WO (1) WO1998035256A1 (pt)

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US7034883B1 (en) * 1999-08-10 2006-04-25 Cellavision Ab Automatic focusing
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DE10159239A1 (de) * 2001-12-03 2003-06-26 Leica Microsystems Mikroskopobjektiv, Mikroskop und Verfahren zum Abbilden einer Probe
US7756305B2 (en) * 2002-01-23 2010-07-13 The Regents Of The University Of California Fast 3D cytometry for information in tissue engineering
FR2836520B1 (fr) * 2002-02-28 2004-07-16 Univ Joseph Fourier Actionneur et moteur osmotiques
IL148664A0 (en) * 2002-03-13 2002-09-12 Yeda Res & Dev Auto-focusing method and device
US20040002154A1 (en) * 2002-04-19 2004-01-01 Palsson Bernhard O. Methods for preparing libraries of unique tags and related screening methods
US7235353B2 (en) * 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
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CN101278190B (zh) * 2005-09-29 2012-12-19 奥林巴斯株式会社 焦点位置决定方法、焦点位置决定装置、微弱光检测装置及微弱光检测方法
US7933435B2 (en) * 2005-11-21 2011-04-26 Vala Sciences, Inc. System, method, and kit for processing a magnified image of biological material to identify components of a biological object
DE102008005355B4 (de) * 2008-01-21 2016-10-06 Carl Zeiss Smt Gmbh Autofokusvorrichtung und Autofokussierverfahren für eine Abbildungsvorrichtung
US9229209B2 (en) * 2008-01-21 2016-01-05 Carl Zeiss Smt Gmbh Autofocus device and autofocusing method for an imaging device
DE102008005356B4 (de) * 2008-01-21 2017-01-26 Carl Zeiss Smt Gmbh Autofokusvorrichtung und Autofokussierverfahren für eine Abbildungsvorrichtung
GB2473814B (en) * 2009-09-16 2014-06-11 Spheritech Ltd Hollow particulate support
JP5626367B2 (ja) * 2011-01-21 2014-11-19 株式会社ニコン 焦点位置維持装置及び顕微鏡
US10001622B2 (en) 2011-10-25 2018-06-19 Sanford Burnham Medical Research Institute Multifunction autofocus system and method for automated microscopy
US9903806B2 (en) 2013-12-17 2018-02-27 Nanometrics Incorporated Focusing system with filter for open or closed loop control
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CN105120161A (zh) * 2015-08-28 2015-12-02 苏州南光电子科技有限公司 一种基于摄像头的全自动显微镜控制***
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Also Published As

Publication number Publication date
WO1998035256A1 (en) 1998-08-13
US5995143A (en) 1999-11-30
AU5909998A (en) 1998-08-26
CA2283088A1 (en) 1998-08-13
JP2001511903A (ja) 2001-08-14
EP1021741A1 (en) 2000-07-26
DE69807512T2 (de) 2003-04-24
CA2283088C (en) 2002-12-03
USRE40674E1 (en) 2009-03-24
ATE223070T1 (de) 2002-09-15
CN1246929A (zh) 2000-03-08
DE69807512D1 (de) 2002-10-02
EP1021741B1 (en) 2002-08-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A,8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1887 DE 06/03/2007.