BR9803296A - Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma. - Google Patents
Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma.Info
- Publication number
- BR9803296A BR9803296A BR9803296-8A BR9803296A BR9803296A BR 9803296 A BR9803296 A BR 9803296A BR 9803296 A BR9803296 A BR 9803296A BR 9803296 A BR9803296 A BR 9803296A
- Authority
- BR
- Brazil
- Prior art keywords
- molecule
- fas
- antibody
- treatment
- prophylaxis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MOLéCULA, ANTICORPO, USO DE UMA MOLéCULA, DNA, VETOR DE DNA RECOMBINANTE, CéLULA HOSPEDEIRA, MICROORGANISMO, PROCESSO PARA PRODUZIR UM ANTICORPO, AGENTE PARA O TRATAMENTO OU PROFILAXIA DE CONDIçõES ATRIBUìVEIS A ANORMALIDADES DO SISTEMA LIGANDO FAS/FAS, USO DE UMA MOLéCULA E HIBRIDOMA". Anticorpos Fas anti-humanos que são reativos cruzados com Fas de camundongo e humano são utilizáveis no tratamento de condições atribuíveis a anormalidades no sistema ligando Fas/Fas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8295397 | 1997-04-01 | ||
JP16908897 | 1997-06-25 | ||
JP27606497 | 1997-10-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9803296A true BR9803296A (pt) | 2000-01-11 |
Family
ID=27304060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9803296-8A BR9803296A (pt) | 1997-04-01 | 1998-04-01 | Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0909816A1 (pt) |
KR (1) | KR19980080993A (pt) |
CN (1) | CN1207395A (pt) |
AR (1) | AR010139A1 (pt) |
AU (1) | AU734758B2 (pt) |
BR (1) | BR9803296A (pt) |
CA (1) | CA2233783A1 (pt) |
CZ (1) | CZ294340B6 (pt) |
HU (1) | HUP9800744A3 (pt) |
ID (1) | ID20117A (pt) |
IL (1) | IL123888A0 (pt) |
NO (1) | NO981454L (pt) |
NZ (1) | NZ330095A (pt) |
PL (1) | PL325667A1 (pt) |
RU (1) | RU2212412C2 (pt) |
TR (1) | TR199800604A2 (pt) |
TW (1) | TW526205B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6972323B1 (en) | 1997-04-01 | 2005-12-06 | Sankyo Company, Limited | Anti-Fas antibodies |
ATE553129T1 (de) * | 1998-01-23 | 2012-04-15 | Hoffmann La Roche | Antikörper gegen humanes il-12 |
AU4772299A (en) * | 1998-06-18 | 2000-01-05 | Karolinska Innovations Ab | Fas peptides and antibodies for modulating apoptosis |
AU757961B2 (en) * | 1998-09-30 | 2003-03-13 | Sankyo Company Limited | Anti-Fas antibodies |
NZ515598A (en) * | 1999-05-24 | 2004-05-28 | Sankyo Co | Synergistic medicinal compositions containing anti-Fas antibody and a compound having a folate antagonistic activity or a dihydrofolate reductase inhibiting activity |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
US20070129291A1 (en) * | 2001-08-01 | 2007-06-07 | Genset S.A. | Genobix agonists and antagonists for use in the treatment of metabolic disorders |
EP2383290B1 (en) | 2001-08-23 | 2019-05-08 | Rsr Limited | Epitope regions of a thyrotropin (tsh) receptor, uses thereof and antibodies thereto |
ES2357225T3 (es) | 2001-11-01 | 2011-04-20 | Uab Research Foundation | Combinaciones de anticuerpos anti-dr5 y anticuerpos anti-dr4 y otros agentes terapéuticos. |
TR201815885T4 (tr) | 2004-01-07 | 2018-11-21 | Novartis Vaccines & Diagnostics Inc | M-csf spesifik monoklonal antikorlar ve bunların kullanımı. |
WO2010013498A1 (ja) * | 2008-08-01 | 2010-02-04 | 学校法人聖マリアンナ医科大学 | 変形性関節症治療剤又は予防剤 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09503672A (ja) * | 1993-10-14 | 1997-04-15 | イミュネックス・コーポレーション | Fas拮抗剤とその利用 |
JPH09508009A (ja) * | 1994-01-07 | 1997-08-19 | イミュネックス・コーポレーション | Fas抗原を結合するリガンド |
AU6091496A (en) * | 1995-06-07 | 1996-12-30 | Chiron Corporation | Antibodies to fas antigen capable of inhibiting apoptosis |
GB9523469D0 (en) * | 1995-11-16 | 1996-01-17 | Sandoz Ltd | Organic compounds |
-
1998
- 1998-03-30 IL IL12388898A patent/IL123888A0/xx unknown
- 1998-03-30 AU AU59701/98A patent/AU734758B2/en not_active Ceased
- 1998-03-31 CA CA002233783A patent/CA2233783A1/en not_active Abandoned
- 1998-03-31 ID IDP980478A patent/ID20117A/id unknown
- 1998-03-31 NZ NZ330095A patent/NZ330095A/xx unknown
- 1998-03-31 TW TW087104806A patent/TW526205B/zh not_active IP Right Cessation
- 1998-03-31 NO NO981454A patent/NO981454L/no not_active Application Discontinuation
- 1998-03-31 RU RU98105631/13A patent/RU2212412C2/ru not_active IP Right Cessation
- 1998-04-01 CZ CZ1998985A patent/CZ294340B6/cs not_active IP Right Cessation
- 1998-04-01 HU HU9800744A patent/HUP9800744A3/hu unknown
- 1998-04-01 PL PL98325667A patent/PL325667A1/xx unknown
- 1998-04-01 CN CN98108265A patent/CN1207395A/zh active Pending
- 1998-04-01 EP EP98302575A patent/EP0909816A1/en not_active Withdrawn
- 1998-04-01 BR BR9803296-8A patent/BR9803296A/pt not_active IP Right Cessation
- 1998-04-01 TR TR1998/00604A patent/TR199800604A2/xx unknown
- 1998-04-01 AR ARP980101481A patent/AR010139A1/es unknown
- 1998-04-01 KR KR1019980011477A patent/KR19980080993A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2233783A1 (en) | 1998-10-01 |
TR199800604A3 (tr) | 1999-10-21 |
PL325667A1 (en) | 1998-10-12 |
NZ330095A (en) | 1998-12-23 |
CZ98598A3 (cs) | 1998-10-14 |
NO981454L (no) | 1998-10-02 |
ID20117A (id) | 1998-10-01 |
AR010139A1 (es) | 2000-05-17 |
CN1207395A (zh) | 1999-02-10 |
HU9800744D0 (en) | 1998-05-28 |
HUP9800744A2 (hu) | 1999-02-01 |
TR199800604A2 (xx) | 1999-10-21 |
IL123888A0 (en) | 1998-10-30 |
HUP9800744A3 (en) | 2001-04-28 |
AU734758B2 (en) | 2001-06-21 |
CZ294340B6 (cs) | 2004-12-15 |
NO981454D0 (no) | 1998-03-31 |
KR19980080993A (ko) | 1998-11-25 |
TW526205B (en) | 2003-04-01 |
RU2212412C2 (ru) | 2003-09-20 |
EP0909816A1 (en) | 1999-04-21 |
AU5970198A (en) | 1998-10-08 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 8A E 9A ANUIDADES |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1908 DE 31/07/2007. |