BR9711117A - Oligossacarídios modificados. - Google Patents
Oligossacarídios modificados.Info
- Publication number
- BR9711117A BR9711117A BR9711117-1A BR9711117A BR9711117A BR 9711117 A BR9711117 A BR 9711117A BR 9711117 A BR9711117 A BR 9711117A BR 9711117 A BR9711117 A BR 9711117A
- Authority
- BR
- Brazil
- Prior art keywords
- modified oligosaccharides
- natural
- modified
- oligosaccharides
- oligosacaries
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96810527 | 1996-08-08 | ||
EP96810526 | 1996-08-08 | ||
EP96810636 | 1996-09-26 | ||
PCT/EP1997/004279 WO1998006730A1 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9711117A true BR9711117A (pt) | 1999-09-08 |
Family
ID=27237868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9711117-1A BR9711117A (pt) | 1996-08-08 | 1997-08-06 | Oligossacarídios modificados. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0920437A1 (id) |
JP (1) | JP2000516224A (id) |
KR (1) | KR20000029862A (id) |
CN (1) | CN1227563A (id) |
AR (1) | AR008283A1 (id) |
AU (1) | AU720381B2 (id) |
BR (1) | BR9711117A (id) |
CA (1) | CA2260854A1 (id) |
CO (1) | CO4900075A1 (id) |
CZ (1) | CZ39099A3 (id) |
ID (1) | ID18010A (id) |
IL (1) | IL127908A0 (id) |
NO (1) | NO990497L (id) |
NZ (1) | NZ334048A (id) |
PE (1) | PE99298A1 (id) |
PL (1) | PL331286A1 (id) |
SK (1) | SK15699A3 (id) |
TR (1) | TR199900245T2 (id) |
WO (1) | WO1998006730A1 (id) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888984A (en) * | 1994-05-12 | 1999-03-30 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
EP1165097B1 (en) * | 1999-02-01 | 2007-05-02 | Dermal Research Laboratories, Inc. | A pharmaceutical composition of complex carbohydrates and their use |
US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
WO2004004636A2 (en) * | 2002-07-03 | 2004-01-15 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis |
BR0315231A (pt) | 2002-10-11 | 2005-08-23 | Yamanouchi Europ Bv | Compostos com base em glicose com afinidade para p-seletina |
WO2005054264A2 (en) * | 2003-11-19 | 2005-06-16 | Glycomimetics, Inc. | Glycomimetic antagonists for both e- and p-selectins |
WO2006127906A1 (en) * | 2005-05-25 | 2006-11-30 | Glycomimetics, Inc. | Heterobifunctional compounds for selectin inhibition |
PT1934236E (pt) | 2005-09-02 | 2012-12-26 | Glycomimetics Inc | Inibidores de pan-selectina heterobifuncionais |
WO2008100453A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines |
AU2008336249B2 (en) | 2007-12-10 | 2015-01-29 | The University Of Queensland | Treatment and prophylaxis |
US8895510B2 (en) | 2008-04-08 | 2014-11-25 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
EP3296310A1 (en) | 2011-12-22 | 2018-03-21 | GlycoMimetics, Inc. | E-selectin antagonist compounds, compositions, and methods of use |
HUE038423T2 (hu) | 2012-12-07 | 2018-10-29 | Glycomimetics Inc | E-szelektin antagonistákat felhasználó vegyületek, készítmények és eljárások vérképzõ sejtek mobilizációjára |
WO2016089872A1 (en) | 2014-12-03 | 2016-06-09 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
US11045485B2 (en) | 2016-01-22 | 2021-06-29 | Glycomimetics, Inc. | Glycomimetic inhibitors of PA-IL and PA-IIL lectins |
WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
WO2018031445A1 (en) | 2016-08-08 | 2018-02-15 | Glycomimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4 |
WO2018068010A1 (en) | 2016-10-07 | 2018-04-12 | Glycomimetics, Inc. | Highly potent multimeric e-selectin antagonists |
EP3596096A1 (en) | 2017-03-15 | 2020-01-22 | GlycoMimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
WO2019108750A1 (en) | 2017-11-30 | 2019-06-06 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
JP7304863B2 (ja) | 2017-12-29 | 2023-07-07 | グリコミメティクス, インコーポレイテッド | E-セレクチンおよびガレクチン-3のヘテロ二機能性阻害剤 |
CN108299525B (zh) * | 2018-01-05 | 2021-03-26 | 佛山科学技术学院 | 路易斯寡糖-x的合成方法 |
CA3091454A1 (en) | 2018-03-05 | 2019-09-12 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
CN109762032A (zh) * | 2019-01-16 | 2019-05-17 | 天津科技大学 | 一种磺酸化路易斯x三糖及其合成方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023031A1 (en) * | 1992-05-08 | 1993-11-25 | The Biomembrane Institute | Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response |
CA2157489A1 (en) * | 1993-03-04 | 1994-09-15 | Masaaki Numata | Lewis-associated compound, process for producing the same, and anti-inflammatory |
CN1125449A (zh) * | 1993-05-14 | 1996-06-26 | 萨依特尔有限公司 | 作为细胞粘附抑制剂的唾液基Lex类似物 |
MX9704893A (es) * | 1994-12-28 | 1997-10-31 | Sumitomo Pharma | Derivados de lewis x y procesos para producir los mismos. |
-
1997
- 1997-08-06 SK SK156-99A patent/SK15699A3/sk unknown
- 1997-08-06 TR TR1999/00245T patent/TR199900245T2/xx unknown
- 1997-08-06 CZ CZ99390A patent/CZ39099A3/cs unknown
- 1997-08-06 WO PCT/EP1997/004279 patent/WO1998006730A1/en not_active Application Discontinuation
- 1997-08-06 BR BR9711117-1A patent/BR9711117A/pt not_active Application Discontinuation
- 1997-08-06 KR KR1019997001025A patent/KR20000029862A/ko not_active Application Discontinuation
- 1997-08-06 PL PL97331286A patent/PL331286A1/xx unknown
- 1997-08-06 JP JP10509358A patent/JP2000516224A/ja active Pending
- 1997-08-06 CA CA002260854A patent/CA2260854A1/en not_active Abandoned
- 1997-08-06 NZ NZ334048A patent/NZ334048A/xx unknown
- 1997-08-06 AU AU43788/97A patent/AU720381B2/en not_active Ceased
- 1997-08-06 CN CN97197077A patent/CN1227563A/zh active Pending
- 1997-08-06 IL IL12790897A patent/IL127908A0/xx unknown
- 1997-08-06 EP EP97941916A patent/EP0920437A1/en not_active Withdrawn
- 1997-08-06 AR ARP970103580A patent/AR008283A1/es unknown
- 1997-08-07 PE PE1997000688A patent/PE99298A1/es not_active Application Discontinuation
- 1997-08-08 ID IDP972766A patent/ID18010A/id unknown
- 1997-08-08 CO CO97045596A patent/CO4900075A1/es unknown
-
1999
- 1999-02-03 NO NO990497A patent/NO990497L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
SK15699A3 (en) | 1999-07-12 |
AU4378897A (en) | 1998-03-06 |
JP2000516224A (ja) | 2000-12-05 |
EP0920437A1 (en) | 1999-06-09 |
IL127908A0 (en) | 1999-11-30 |
NO990497D0 (no) | 1999-02-03 |
CO4900075A1 (es) | 2000-03-27 |
CN1227563A (zh) | 1999-09-01 |
NZ334048A (en) | 2000-05-26 |
CZ39099A3 (cs) | 1999-05-12 |
AU720381B2 (en) | 2000-06-01 |
NO990497L (no) | 1999-03-24 |
PL331286A1 (en) | 1999-07-05 |
WO1998006730A1 (en) | 1998-02-19 |
TR199900245T2 (xx) | 1999-05-21 |
PE99298A1 (es) | 1999-01-21 |
AR008283A1 (es) | 1999-12-29 |
KR20000029862A (ko) | 2000-05-25 |
ID18010A (id) | 1998-02-19 |
CA2260854A1 (en) | 1998-02-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |