BR9609285A - Diglycosylated diols-1,2 as mimetics of sialyl-lewis x and sialyl-lewis a - Google Patents

Diglycosylated diols-1,2 as mimetics of sialyl-lewis x and sialyl-lewis a

Info

Publication number: BR9609285A
Authority: BR; Brazil
Prior art keywords: sialyl; lewis; diglycosylated; mimetics; diols
Prior art date: 1995-06-29

Application number

BR9609285A

Other languages

Portuguese (pt)

Inventor

Hartmuth Christian Kolb

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-29

Filing date

1996-06-26

Publication date

1999-05-11

1996-06-26 Application filed by Novartis Ag filed Critical Novartis Ag

1999-05-11 Publication of BR9609285A publication Critical patent/BR9609285A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Oncology (AREA)
Rheumatology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Cosmetics (AREA)

BR9609285A 1995-06-29 1996-06-26 Diglycosylated diols-1,2 as mimetics of sialyl-lewis x and sialyl-lewis a BR9609285A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH191495		1995-06-29
PCT/EP1996/002785 WO1997001569A1 (en)	1995-06-29	1996-06-26	Diglycosylated 1,2-diols as mimetics of sialyl-lewis x and sialyl-lewis a

Publications (1)

Publication Number	Publication Date
BR9609285A true BR9609285A (en)	1999-05-11

Family

ID=4221546

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9609285A BR9609285A (en)	1995-06-29	1996-06-26	Diglycosylated diols-1,2 as mimetics of sialyl-lewis x and sialyl-lewis a

Country Status (19)

Country	Link
EP (1)	EP0836610A1 (en)
JP (1)	JPH11508548A (en)
KR (1)	KR19990028543A (en)
CN (1)	CN1196731A (en)
AU (1)	AU707474B2 (en)
BR (1)	BR9609285A (en)
CA (1)	CA2224346A1 (en)
CZ (1)	CZ419797A3 (en)
EA (1)	EA001356B1 (en)
HU (1)	HUP9801805A3 (en)
IL (1)	IL118740A0 (en)
MX (1)	MX9800218A (en)
NO (1)	NO976065L (en)
NZ (1)	NZ311686A (en)
PL (1)	PL324258A1 (en)
SI (1)	SI9620099A (en)
SK (1)	SK177897A3 (en)
TR (1)	TR199701728T1 (en)
WO (1)	WO1997001569A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE502928T1 (en)	2000-11-01	2011-04-15	Millennium Pharm Inc	NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
EP1577289A1 (en) *	2004-03-18	2005-09-21	Revotar Biopharmaceuticals AG	Non-glycosylated/-glycosidic/-peptidic small molecule selectin inhibitors for the treament of inflammatory disorders
DK2264043T3 (en) *	2005-09-02	2018-01-29	Glycomimetics Inc	Heterobifunctional pan-selectin inhibitors
EP1764095A1 (en)	2005-09-20	2007-03-21	Revotar Biopharmaceuticals AG	Novel nitrocatechol derivatives having selectin ligand activity
EP1764093A1 (en)	2005-09-20	2007-03-21	Revotar Biopharmaceuticals AG	Novel aromatic compounds and their use in medical applications
EP1764096A1 (en)	2005-09-20	2007-03-21	Revotar Biopharmaceuticals AG	Novel phloroglucinol derivatives having selectin ligand activity
CA2666103C (en) *	2006-10-12	2014-02-18	Glycomimetics, Inc.	Glycomimetic replacements for hexoses and n-acetyl hexosamines
EP2117561A1 (en) *	2007-02-09	2009-11-18	GlycoMimetics, Inc.	Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines
US8895510B2 (en)	2008-04-08	2014-11-25	Glycomimetics, Inc.	Pan-selectin inhibitor with enhanced pharmacokinetic activity
US8921328B2 (en)	2010-09-14	2014-12-30	Glycomimetics, Inc.	E-selectin antagonists
KR102055958B1 (en)	2011-12-22	2019-12-13	글리코미메틱스, 인크.	E-selectin antagonist compounds, compositions, and methods of use
US9867841B2 (en)	2012-12-07	2018-01-16	Glycomimetics, Inc.	Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells
JP6689854B2 (en)	2014-12-03	2020-04-28	グリコミメティクス，インコーポレイテッド	Heterobifunctional inhibitors of E-selectin and CXCR4 chemokine receptors
CA3009836A1 (en)	2016-01-22	2017-07-27	Glycomimetics, Inc.	Glycomimetic inhibitors of pa-il and pa-iil lectins
WO2017151708A1 (en)	2016-03-02	2017-09-08	Glycomimetics, Inc.	Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
EP3497131B1 (en)	2016-08-08	2022-03-09	GlycoMimetics, Inc.	Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4.
KR102607640B1 (en)	2016-10-07	2023-11-28	글리코미메틱스, 인크.	Very potent multimeric E-selectin antagonist
US11197877B2 (en)	2017-03-15	2021-12-14	Glycomimetics. Inc.	Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists
EP3717013A1 (en)	2017-11-30	2020-10-07	GlycoMimetics, Inc.	Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
AU2018395417B2 (en)	2017-12-29	2023-07-13	Glycomimetics, Inc.	Heterobifunctional inhibitors of E-selectin and galectin-3
CA3091454A1 (en)	2018-03-05	2019-09-12	Glycomimetics, Inc.	Methods for treating acute myeloid leukemia and related conditions
US11845771B2 (en)	2018-12-27	2023-12-19	Glycomimetics, Inc.	Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5326752A (en) *	1991-11-27	1994-07-05	Glycomed Incorporated	Substituted lactose and lactosamine derivatives as cell adhesion inhibitors
WO1993023031A1 (en) *	1992-05-08	1993-11-25	The Biomembrane Institute	Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response
CA2100412A1 (en) *	1992-07-15	1994-01-16	Yutaka Yamada	Glycolipid derivatives

1996
- 1996-06-26 CN CN96196452A patent/CN1196731A/en active Pending
- 1996-06-26 JP JP9504171A patent/JPH11508548A/en active Pending
- 1996-06-26 EA EA199800103A patent/EA001356B1/en not_active IP Right Cessation
- 1996-06-26 CZ CZ974197A patent/CZ419797A3/en unknown
- 1996-06-26 HU HU9801805A patent/HUP9801805A3/en unknown
- 1996-06-26 CA CA002224346A patent/CA2224346A1/en not_active Abandoned
- 1996-06-26 SI SI9620099A patent/SI9620099A/en unknown
- 1996-06-26 IL IL11874096A patent/IL118740A0/en unknown
- 1996-06-26 TR TR97/01728T patent/TR199701728T1/en unknown
- 1996-06-26 WO PCT/EP1996/002785 patent/WO1997001569A1/en not_active Application Discontinuation
- 1996-06-26 KR KR1019970709861A patent/KR19990028543A/en not_active Application Discontinuation
- 1996-06-26 SK SK1778-97A patent/SK177897A3/en unknown
- 1996-06-26 NZ NZ311686A patent/NZ311686A/en unknown
- 1996-06-26 PL PL96324258A patent/PL324258A1/en unknown
- 1996-06-26 AU AU63053/96A patent/AU707474B2/en not_active Ceased
- 1996-06-26 BR BR9609285A patent/BR9609285A/en not_active Application Discontinuation
- 1996-06-26 EP EP96922034A patent/EP0836610A1/en not_active Ceased
1997
- 1997-12-23 NO NO976065A patent/NO976065L/en not_active Application Discontinuation
1998
- 1998-01-07 MX MX9800218A patent/MX9800218A/en unknown

Also Published As

Publication number	Publication date
HUP9801805A3 (en)	2002-01-28
IL118740A0 (en)	1996-10-16
EP0836610A1 (en)	1998-04-22
PL324258A1 (en)	1998-05-11
SI9620099A (en)	1998-08-31
NO976065D0 (en)	1997-12-23
AU6305396A (en)	1997-01-30
AU707474B2 (en)	1999-07-08
CA2224346A1 (en)	1997-01-16
TR199701728T1 (en)	1998-03-21
CN1196731A (en)	1998-10-21
MX9800218A (en)	1998-07-31
CZ419797A3 (en)	1998-06-17
KR19990028543A (en)	1999-04-15
EA001356B1 (en)	2001-02-26
WO1997001569A1 (en)	1997-01-16
EA199800103A1 (en)	1998-08-27
SK177897A3 (en)	1998-08-05
HUP9801805A2 (en)	1998-12-28
NZ311686A (en)	2000-01-28
JPH11508548A (en)	1999-07-27
NO976065L (en)	1998-02-17

Legal Events

Date	Code	Title	Description
2005-04-19	B11A	Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
2005-09-13	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]

Publication	Publication Date	Title
BR9609285A (en)	1999-05-11	Diglycosylated diols-1,2 as mimetics of sialyl-lewis x and sialyl-lewis a
LV11614A (en)	1996-12-20	Alaninamide with antidiabetic activity
DE69617424D1 (en)	2002-01-10	ELASTIC CLOTHING
FI98968B (en)	1997-05-30	Keyboard and key
GB2303251B (en)	1998-11-25	Keyboard
PL323460A1 (en)	1998-03-30	Alphameric keyboard
DE19680279T1 (en)	1997-05-28	Antibacterial keyboard
DE69532591D1 (en)	2004-03-25	NEW KERATE SULFATE HYDROLASE
DE59606858D1 (en)	2001-06-13	Press section
BR9507572A (en)	1997-08-05	Post-filtering and post-filtering process
NO974334D0 (en)	1997-09-19	Fiber-containing polyurea lubricant
GB2297502B (en)	1999-12-08	Harvester-knife cylinder and blower-assist
LV11542A (en)	1996-10-20	Substituted 1,3,9,11-tetraoxa-4,5,7,8-tetraazaundecadien-4,7-dioxide-5,7, their uptake and application
DE59608536D1 (en)	2002-02-07	instrumentation fitting
FI98114B (en)	1997-01-15	transmission arrangement
IL110496A0 (en)	1994-10-21	Rekeyable cylinder and its keys
GB2306749B (en)	1997-10-29	Desk-mat with keyboard instrument
DE69516142D1 (en)	2000-05-11	keyboard
KR970030425U (en)	1997-07-24	Cylinder block and transmission assembly structure
FR2736832B1 (en)	1997-09-19	INTERFERON-GAMMA POTENTIALIZING AGENT
GB9618412D0 (en)	1996-10-16	Elongate fibrous members
KR200161841Y1 (en)	2000-03-15	Antibacterial keyboard
BR7502341U (en)	1998-04-28	Stamp arrangement
AU1608P (en)	2000-11-23	Bolta Trifolium michelianum
NO974154D0 (en)	1997-09-09	Pigg